StrokeCEOPSNCT02132364
Controlled Education Of Patients After Stroke
A study testing optimised follow-up in people with Stroke and Hypertension, run by University Hospital, Lille at 17 sites in France.
Trial summary
The main objective of the study is to compare the benefit of optimised follow-up by nursing personnel from the vascular neurology department, including therapeutic follow-up and an educational program directed to the patient and a caregiving member of his social circle, with that of a typical follow-up. Read more about this study
- Who is it for?
- Ages 60 to 90 years
- Conditions the study is for
- Stroke, Hypertension
- What is being tested?
- optimised follow-up
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 290 participants
- Where
- 17 sitesFrance
- Study dates
- 30 Jan 2014to 16 Dec 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 to 90 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients over 60 years of age
- Patients who have had a first stroke, transient or permanent, ischaemic or haemorrhagic, justifying hospitalisation
- Patients with high blood pressure already treated or discovered at the time of the stroke and justifying the start of a treatment
- Patients who have had a stroke with sequelae allowing immediate return home or justifying a stay of less than one month in rehabilitation
- Patient having a member of his social circle who has agreed to provide follow-up for two years in association with the assigned nursing personnel in case of randomisation into the "optimised follow-up" group.
Who cannot join
- Patients less than 60 years of age
- Patients with a history of stroke
- Patients who do not have high blood pressure discovered by a treatment prior to the stroke or by abnormal blood pressure figures during hospitalisation
- Patients who have had a stroke causing serious sequelae, justifying an extended stay in a rehabilitation department
- Patient who has no one in his social circle capable of working with the assigned nursing personnel, or patient living in an institution
Trial locations and contacts
17 sites in 1 country.
17 sites in 1 country
France17 sites
Chu Amiens Picardie
Amiens
CHU
Besançon, 25000
CHU
Bordeaux, 33076
Chru Brest
Brest
Hopital Pierre Wertheimer - Hcl
Bron
CH
Calais, 62100
Samsah Ghicl Capinghem
Capinghem
Ch Intercommunal Compiègne-Noyon - Compiegne
Compiègne
CHU
Dijon, 21000
Chu de Grenoble Alpes - Grenoble 9
Grenoble
CHRU
Lille, 59037
C H U Dupuytren Limoges
Limoges
Ch Sambre Avesnois Maubeuge
Maubeuge
Ch Saint Joseph
Paris, 75674
Chu La Miletrie - Poitiers
Poitiers
CHU
Rouen, 76031
Chru Nancy - Hopitaux de Braboi
Vandœuvre-lès-Nancy
About this study
The main objective of the study is to compare the benefit of optimised follow-up by nursing personnel from the vascular neurology department, including therapeutic follow-up and an educational program directed to the patient and a caregiving member of his social circle, with that of a typical follow-up.
- Conditions
- Stroke, Hypertension
- Being tested
- optimised follow-up
- Keywords
- stroke, hypertension, secondary prevention, educational program
- Medical subject headings
- Stroke, Hypertension
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
optimised follow-upOther
optimised follow-up will be done by nursing personnel associated with a caregiving member of his social circle.
| Study group | Role | What they receive |
|---|---|---|
| optimised follow-up | Other | optimised follow-up will be done by nursing personnel associated with a caregiving member of his social circle. Receives: Other: optimised follow-up |
| typical follow-up | No intervention | no intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
blood pressure
blood pressure will be measured by nursing personnel who do not know the group into which the patient has been randomised.
Measured: 12 months
Secondary outcomes (1)
Outcome of stroke
functional handicap (Rankin scale) cognitive state (MoCA scale)
Measured: 6 months 12 months 2 years.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 May 2014 (estimated)
- Study start30 Jan 2014
- Primary completion16 Dec 2021
- Study completion16 Dec 2021
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by University Hospital, LilleThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 290 participants (actual)
Sponsor and investigators
- Lead sponsor
- University Hospital, Lille
- Sponsor type
- University, hospital or other
- Collaborators
- Ministry of Health, France
- Responsible party
- Sponsor
- Investigators
- REGIS BORDET, MD phD, Principal investigator, University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02132364
- Sponsor's protocol ID
- 2011_34
- Other IDs
- 2012-A00473-40, PHRIP 2012 - N°12-019-0306
- Acronym
- CEOPS
- Status last verified
- Feb 2023
- First submitted
- 5 May 2014
- Last updated
- 16 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- Individual data sharing
- No
Publications
Mendyk AM, Duhamel A, Bejot Y, Leys D, Derex L, Dereeper O, Detante O, Garcia PY, Godefroy O, Montoro FM, Neau JP, Richard S, Rosolacci T, Sibon I, Sablot D, Timsit S, Zuber M, Cordonnier C, Bordet R; on the behalf of Strokavenir network. Controlled Education of patients after Stroke (CEOPS)- nurse-led multimodal and long-term interventional program involving a patient's caregiver to optimize secondary prevention of stroke: study protocol for a randomized controlled trial. Trials. 2018 Feb 22;19(1):137. doi: 10.1186/s13063-018-2483-0.
PubMed 29471839Crocker TF, Brown L, Lam N, Wray F, Knapp P, Forster A. Information provision for stroke survivors and their carers. Cochrane Database Syst Rev. 2021 Nov 23;11(11):CD001919. doi: 10.1002/14651858.CD001919.pub4.
PubMed 34813082
Study at a glance
From the registry record, last updated by the sponsor on 16 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Controlled Education Of Patients After Stroke
- ClinicalTrials.gov ID
- NCT02132364
- Acronym / sponsor ID
- CEOPS / 2011_34
- Conditions
- Stroke, Hypertension
- Keywords
- stroke, hypertension, secondary prevention, educational program
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 290 participants (actual)
- Lead sponsor
- University Hospital, LilleUniversity, hospital or other
- Collaborators
- Ministry of Health, France
- Study start
- 30 Jan 2014 (actual)
- Primary completion
- 16 Dec 2021 (actual)
- Study completion
- 16 Dec 2021 (actual)
- First posted
- 7 May 2014 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The main objective of the study is to compare the benefit of optimised follow-up by nursing personnel from the vascular neurology department, including therapeutic follow-up and an educational program directed to the patient and a caregiving member of his social circle, with that of a typical follow-up.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| optimised follow-up | Other | Other: optimised follow-upoptimised follow-up will be done by nursing personnel associated with a caregiving member of his social circle. |
| typical follow-up | No intervention | –no intervention |
Who may qualify
- Ages
- 60 to 90 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Patients over 60 years of age
- Patients who have had a first stroke, transient or permanent, ischaemic or haemorrhagic, justifying hospitalisation
- Patients with high blood pressure already treated or discovered at the time of the stroke and justifying the start of a treatment
- Patients who have had a stroke with sequelae allowing immediate return home or justifying a stay of less than one month in rehabilitation
- Patient having a member of his social circle who has agreed to provide follow-up for two years in association with the assigned nursing personnel in case of randomisation into the "optimised follow-up" group.
Key exclusion criteria (5 listed)
- Patients less than 60 years of age
- Patients with a history of stroke
- Patients who do not have high blood pressure discovered by a treatment prior to the stroke or by abnormal blood pressure figures during hospitalisation
- Patients who have had a stroke causing serious sequelae, justifying an extended stay in a rehabilitation department
- Patient who has no one in his social circle capable of working with the assigned nursing personnel, or patient living in an institution
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| optimised follow-upoptimised follow-up will be done by nursing personnel associated with a caregiving member of his social circle. | Other | optimised follow-up |
Primary outcome
blood pressure
Time frame: 12 months
blood pressure will be measured by nursing personnel who do not know the group into which the patient has been randomised.
1 secondary outcome
Outcome of stroke
Time frame: 6 months 12 months 2 years.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Dec 2025.
- Background: PubMed 29471839Mendyk AM, Duhamel A, Bejot Y, Leys D, Derex L, Dereeper O, Detante O, Garcia PY, Godefroy O, Montoro FM, Neau JP, Richard S, Rosolacci T, Sibon I, Sablot D, Timsit S, Zuber M, Cordonnier C, Bordet R; on the behalf of Strokavenir network. Controlled Education of patients after Stroke (CEOPS)- nurse-led multimodal and long-term interventional program involving a patient's caregiver to optimize secondary prevention of stroke: study protocol for a randomized controlled trial. Trials. 2018 Feb 22;19(1):137. doi: 10.1186/s13063-018-2483-0.
- Derived from this study: PubMed 34813082Crocker TF, Brown L, Lam N, Wray F, Knapp P, Forster A. Information provision for stroke survivors and their carers. Cochrane Database Syst Rev. 2021 Nov 23;11(11):CD001919. doi: 10.1002/14651858.CD001919.pub4.
- Individual participant dataSharing planned: No
Related trials for Stroke
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ELATE Study: Evaluating Large-vessel Acute Thrombectomy in Extended Time Window
Acute Ichemic Stroke
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Web-Based Tele-Rehabilitation Using Action Observation and Mirror Therapy for Subacute Stroke: A Randomized Controlled Trial
Stroke, Upper Extremity Paresis
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Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Subarachnoid Aneurysm Hemorrhage
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Selective Intra-Arterial Hypothermia After Endovascular Treatment for Acute Basilar Artery Occlusion
Acute Ischemic Stroke, Basilar Artery Occlusion
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
REGIS BORDET, MD phD principal investigator
University Hospital
17 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing optimised follow-up in people with Stroke and Hypertension, run by University Hospital, Lille at 17 sites in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 17 sites in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
blood pressure (time frame: 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02132364, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Dec 2025.