Fourth Cranial Nerve PalsyIVPareseZahnNCT02149355
Teeth and Jaw Misalignment in Patients Suffering From Congenital Fourth Cranial Nerve Palsy
An observational study of Fourth Cranial Nerve Palsy, run by University of Zurich at 1 site in Switzerland.
Trial summary
Patients suffering from congenital fourth cranial nerve palsy may have misalignment of jaws as well as teeth due to head tilt in childhood. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Fourth Cranial Nerve Palsy
- What is being tested?
- teeth molding
- How many people
- 50 participants
- Where
- 1 siteSwitzerland
- Study dates
- Mar 2014to Dec 2017
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: patients suffering from congenital fourth nerve palsy
Who may be able to join
- unilateral congenital fourth nerve palsy
- natural teeth occlusion
- age > 18 years
Who cannot join
- bilateral fourth nerve palsy
- no natural teeth occlusion
Trial locations and contacts
1 site in 1 country.
Switzerland1 site, 1 recruiting
- Recruiting
UniversityHospital Zurich
Zurich, Canton of Zurich, 8091
Gregor Jaggi, MD, 0041 44 255 49 00, gregor.jaggi@usz.ch
Gregor Jaggi, MD
About this study
Patients suffering from congenital fourth cranial nerve palsy may have misalignment of jaws as well as teeth due to head tilt in childhood.
Read the detailed description
Measurement of teeth and jaw parameters in patients suffering from congenital fourth cranial nerve palsy compared to patients without fourth cranial nerve palsy.
- Conditions
- Fourth Cranial Nerve Palsy
- Being tested
- teeth molding
- Keywords
- teeth position, jaw alignment
- Medical subject headings
- Trochlear Nerve Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
teeth moldingOther
teeth molding in patients suffering from congenital fourth nerve palsy
| Study group | Role | What they receive |
|---|---|---|
| controls | teeth molding in subjects without congenital fourth nerve palsy Receives: Other: teeth molding | |
| congenital fourth nerve palsy | teeth molding in patients suffering from congenital fourth nerve palsy Receives: Other: teeth molding |
What is being measured
The primary outcome is the main question the study is designed to answer.
angle between teeth positions from upper and lower jaw
The angle between teeth positions from upper and lower jaw will be measured using teeth molding.
Measured: 3 to 6 months after recruitment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 May 2014 (estimated)
- Study startMar 2014
- Primary completionMar 2017 (estimated)
- Study completionDec 2017 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Fourth Cranial Nerve PalsyStudies of the same condition, open and under way.
- More trials run by University of ZurichThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Retrospective
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Zurich
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Klara Landau, Prof MD, Study chair, University Hospital Zurich, ophthalmology department
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02149355
- Sponsor's protocol ID
- KEK-ZH 2013-0342
- Other IDs
- KEK-ZH 2013-0342
- Acronym
- IVPareseZahn
- Status last verified
- May 2014
- First submitted
- 7 Apr 2014
- Last updated
- 29 May 2014
- Results posted
- No
- Data monitoring committee
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 29 May 2014. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Teeth and Jaw Misalignment in Patients Suffering From Congenital Fourth Cranial Nerve Palsy
- ClinicalTrials.gov ID
- NCT02149355
- Acronym / sponsor ID
- IVPareseZahn / KEK-ZH 2013-0342
- Conditions
- Fourth Cranial Nerve Palsy
- Keywords
- teeth position, jaw alignment
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- University of ZurichUniversity, hospital or other
- Study start
- Mar 2014
- Primary completion
- Mar 2017 (estimated)
- Study completion
- Dec 2017 (estimated)
- First posted
- 29 May 2014 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Patients suffering from congenital fourth cranial nerve palsy may have misalignment of jaws as well as teeth due to head tilt in childhood.
Detailed description
Measurement of teeth and jaw parameters in patients suffering from congenital fourth cranial nerve palsy compared to patients without fourth cranial nerve palsy.
Study design
- Observational model
- Case-control
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| controls | – | Other: teeth moldingteeth molding in subjects without congenital fourth nerve palsy |
| congenital fourth nerve palsy | – | Other: teeth moldingteeth molding in patients suffering from congenital fourth nerve palsy |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- patients suffering from congenital fourth nerve palsy
Key inclusion criteria (3 listed)
- unilateral congenital fourth nerve palsy
- natural teeth occlusion
- age > 18 years
Key exclusion criteria (2 listed)
- bilateral fourth nerve palsy
- no natural teeth occlusion
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| teeth moldingteeth molding in patients suffering from congenital fourth nerve palsy | Other | congenital fourth nerve palsy, controls |
Primary outcome
angle between teeth positions from upper and lower jaw
Time frame: 3 to 6 months after recruitment
The angle between teeth positions from upper and lower jaw will be measured using teeth molding.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 May 2014.
- official homepage of swiss federal governmentLink provided by the sponsor.
Related trials for Fourth Cranial Nerve Palsy
RecruitingObservational study
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies
Congenital Fibrosis of Extraocular Muscles, Duane Retraction Syndrome
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Klara Landau, Prof MD study chair
University Hospital Zurich, ophthalmology department
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Fourth Cranial Nerve Palsy, run by University of Zurich at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 29 May 2014. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Gregor Jaggi, MD (0041 44 255 49 00, gregor.jaggi@usz.ch), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
angle between teeth positions from upper and lower jaw (time frame: 3 to 6 months after recruitment). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 May 2014.