DehydrationHANDsOnNCT02230774
Hydration Amongst Nurses and Doctors Oncall
An observational study of Dehydration, run by University of Nottingham at 1 site in United Kingdom.
Trial summary
The main purpose of this study is to assess and compare the hydration status of medical and nursing staff and to investigate the relationship between the hydration status, cognitive function and serum cortisol (marker of stress). Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Dehydration
- How many people
- 88 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- Mar 2013to Jul 2014
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Nurses and doctors oncall working on acute medical and surgical admissions wards at the Queens Medical Centre Nottingham
Who may be able to join
- All medical and nursing staff working on acute medical and surgical admissions at the Queens Medical Centre Nottingham
Who cannot join
- Pregnancy Pre-existing kidney disease Patients on diuretics Unwell in the past 6 week with acute illness that warrants hospital admission or prescribed medication.
Trial locations and contacts
1 site in 1 country.
United Kingdom1 site
Queens Medical Centre
Nottingham, Nottinghamshire, NG7 2UH
About this study
The main purpose of this study is to assess and compare the hydration status of medical and nursing staff and to investigate the relationship between the hydration status, cognitive function and serum cortisol (marker of stress).
We hypothesise that a significant proportion of doctors and nurses will be dehydrated at the end of their working day. Some, as in other occupations, may be dehydrated at the start of their working day. This is likely to be associated with impairment in cognitive performance at the end of the working day compared to the beginning and expected to be more pronounced after a night shift. There may be less noticeable difference amongst nursing staff given the protected break time. Dehydration and associated impairment in cognition is of important clinical value as it can impact patient care. participants will be involved in the study for two shifts (one day and one night), aiming at 15 medical and 15 surgical nurses as well as 15 medical (total 15 day and 15 night shifts from each group) and surgical doctors (total 15 day and 15 night shifts from each group). Those that do not work both day and night shifts will participate for only one shift and a new participant will be recruited until target number of shifts is achieved.
Read the detailed description
End points
- To assess the hydration status of hospital staff nurses and doctors oncall at work by measuring the following:
- Urine and serum osmolality
- Urine mass produced during the shift
- Kidney function (U \&Es)
- Bioimpedance measures 2- To assess the effect of hydration on status of cognitive function and subjective feelings. 3- To assess the association between hydration status on stress hormone (cortisol) levels. Inclusion criteria All medical and nursing staff working on acute medical and surgical admissions at the Queens Medical Centre Nottingham. Exclusion Criteria: Pregnancy Pre-existing kidney disease Patients on diuretics Unwell in the past 6 week with acute illness that warrants hospital admission or prescribed medication.
- Conditions
- Dehydration
- Keywords
- hydration, cognitive function, doctors, nurses, Nurses and Doctors oncall
- Medical subject headings
- Dehydration
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| medical staff | Nurses and doctors oncall |
What is being measured
The primary outcome is the main question the study is designed to answer.
Assess the prevalence of dehydration in nurses and doctors oncall.
Using urine osmolality as a marker of hydration we aim to assess the prevalence of dehydration in health care professionals before and after day and night shifts. Comparing nurses and doctors oncall, day and night as well diffrence between those working in medical and surgical admissions.
Measured: Participants will be followed up for the duration of their shift, approximately 12- 14 hours.
Secondary outcomes (2)
Impact of hydration status on cognitive function
We aim to assess the impact of hydration on key executive cognitive before and after day and night shifts, comparing day and night using the following tests:
- Visual search
- Stroop
- Sternberg
- Corsi
Measured: Participants will be followed up for the duration of their shift, approximately 12- 14 hours.
The impact of hydration status on serum cortisol concentrations
The impact of hydration status on serum cortisol concentrations as a surrogate marker of stress will be assessed before and after day and night shifts. with day and night shifts assessed separately given the diurnal variations in cortisol.
Measured: Participants will be followed up for the duration of their shift, approximately 12- 14 hours.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Sep 2014 (estimated)
- Study startMar 2013
- Primary completionJul 2014
- Study completionJul 2014
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for DehydrationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 88 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Nottingham
- Sponsor type
- University, hospital or other
- Collaborators
- European Hydration Institute, Loughborough University
- Responsible party
- Sponsor
- Investigators
- Dileep N Lobo, MBBS,DM,FRCS, Study chair, University of NottinghamDileep N Lobo, MBBS,DM,FRCS, Principal investigator, University of Nottingham
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02230774
- Sponsor's protocol ID
- 12118
- Acronym
- HANDsOn
- Status last verified
- Sep 2014
- First submitted
- 14 Jul 2014
- Last updated
- 3 Sep 2014
- Results posted
- No
- Data monitoring committee
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Sep 2014. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Hydration Amongst Nurses and Doctors Oncall
- ClinicalTrials.gov ID
- NCT02230774
- Acronym / sponsor ID
- HANDsOn / 12118
- Conditions
- Dehydration
- Keywords
- hydration, cognitive function, doctors, nurses, Nurses and Doctors oncall
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 88 participants (actual)
- Lead sponsor
- University of NottinghamUniversity, hospital or other
- Collaborators
- European Hydration Institute, Loughborough University
- Study start
- Mar 2013
- Primary completion
- Jul 2014 (actual)
- Study completion
- Jul 2014 (actual)
- First posted
- 3 Sep 2014 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The main purpose of this study is to assess and compare the hydration status of medical and nursing staff and to investigate the relationship between the hydration status, cognitive function and serum cortisol (marker of stress).
We hypothesise that a significant proportion of doctors and nurses will be dehydrated at the end of their working day. Some, as in other occupations, may be dehydrated at the start of their working day. This is likely to be associated with impairment in cognitive performance at the end of the working day compared to the beginning and expected to be more pronounced after a night shift. There may be less noticeable difference amongst nursing staff given the protected break time. Dehydration and associated impairment in cognition is of important clinical value as it can impact patient care. participants will be involved in the study for two shifts (one day and one night), aiming at 15 medical and 15 surgical nurses as well as 15 medical (total 15 day and 15 night shifts from each group) and surgical doctors (total 15 day and 15 night shifts from each group). Those that do not work both day and night shifts will participate for only one shift and a new participant will be recruited until target number of shifts is achieved.
Detailed description
End points
- To assess the hydration status of hospital staff nurses and doctors oncall at work by measuring the following:
- Urine and serum osmolality
- Urine mass produced during the shift
- Kidney function (U \&Es)
- Bioimpedance measures 2- To assess the effect of hydration on status of cognitive function and subjective feelings. 3- To assess the association between hydration status on stress hormone (cortisol) levels. Inclusion criteria All medical and nursing staff working on acute medical and surgical admissions at the Queens Medical Centre Nottingham. Exclusion Criteria: Pregnancy Pre-existing kidney disease Patients on diuretics Unwell in the past 6 week with acute illness that warrants hospital admission or prescribed medication.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| medical staff | – | –Nurses and doctors oncall |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Nurses and doctors oncall working on acute medical and surgical admissions wards at the Queens Medical Centre Nottingham
Key inclusion criteria (1 listed)
- All medical and nursing staff working on acute medical and surgical admissions at the Queens Medical Centre Nottingham
Key exclusion criteria (1 listed)
- Pregnancy Pre-existing kidney disease Patients on diuretics Unwell in the past 6 week with acute illness that warrants hospital admission or prescribed medication.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Assess the prevalence of dehydration in nurses and doctors oncall.
Time frame: Participants will be followed up for the duration of their shift, approximately 12- 14 hours.
Using urine osmolality as a marker of hydration we aim to assess the prevalence of dehydration in health care professionals before and after day and night shifts. Comparing nurses and doctors oncall, day and night as well diffrence between those working in medical and surgical admissions.
2 secondary outcomes
Impact of hydration status on cognitive function
Time frame: Participants will be followed up for the duration of their shift, approximately 12- 14 hours.
The impact of hydration status on serum cortisol concentrations
Time frame: Participants will be followed up for the duration of their shift, approximately 12- 14 hours.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Sep 2014.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Dileep N Lobo, MBBS,DM,FRCS study chair
University of Nottingham
Dileep N Lobo, MBBS,DM,FRCS principal investigator
University of Nottingham
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Dehydration, run by University of Nottingham at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Sep 2014. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Assess the prevalence of dehydration in nurses and doctors oncall. (time frame: Participants will be followed up for the duration of their shift, approximately 12- 14 hours.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Sep 2014; AzTrials last refreshed its copy on 29 Oct 2026.