AnemiaNCT02466672
The Role and Effect of Anemia in Children With Pneumonia
An observational study of Anemia and Pneumonia, run by Massachusetts General Hospital at 1 site in Uganda.
Trial summary
This study will measure the effect of anemia on the outcomes of hospitalized children with severe pneumonia. Read more about this study
- Who is it for?
- Ages 6 to 59 months
- What is being tested?
- none - observational only
- How many people
- 212 participants
- Where
- 1 siteUganda
- Study dates
- Feb 2015to Jan 2016
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 to 59 months
- All sexes
- No healthy volunteers
- Child
Study population: Children age 6 months to 59 months admitted to the hospital with WHO-defined severe pneumonia
Who may be able to join
- Age 6 months to 59 months
- WHO-defined severe pneumonia
Who cannot join
- Congenital heart disease
Trial locations and contacts
1 site in 1 country.
About this study
This study will measure the effect of anemia on the outcomes of hospitalized children with severe pneumonia.
- Being tested
- none - observational only
- Medical subject headings
- Anemia, Pneumonia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
none - observational onlyOther
What is being measured
The primary outcome is the main question the study is designed to answer.
Time to recovery from pneumonia
Measured: participants will be followed for the duration of hospital stay, an expected average of 5 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jun 2015 (estimated)
- Study startFeb 2015
- Primary completionJan 2016
- Study completionJan 2016
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for AnemiaStudies of the same condition, open and under way.
- More trials run by Massachusetts General HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 212 participants (actual)
Sponsor and investigators
- Lead sponsor
- Massachusetts General Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Mbarara University of Science and Technology, Thrasher Research Fund, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
- Responsible party
- Principal investigator, Peter Moschovis, Massachusetts General Hospital
- Investigators
- Peter P Moschovis, MD, Principal investigator, Massachusetts General Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02466672
- Sponsor's protocol ID
- 2014P001325
- Other IDs
- 5F32HL124951-03
- Status last verified
- Jul 2019
- First submitted
- 3 Jun 2015
- Last updated
- 25 Jul 2019
- Results posted
- No
- Data monitoring committee
- No
Publications
Moschovis PP, Sharfi A, Chaudhury S, Sharma A, Wiens MO, Kumbakumba E, Keneema O, Nyehengane D, Kabakyenga J, Ansermino JM, Kissoon N, Christiani DC, Dzik W, Kiwanuka JP, Hibberd PL. The Effect of Anemia on Mortality in Children Hospitalized with Severe Pneumonia in Uganda. J Pediatr. 2026 Jul;294:115090. doi: 10.1016/j.jpeds.2026.115090. Epub 2026 Mar 30.
PubMed 41921770
Study at a glance
From the registry record, last updated by the sponsor on 25 Jul 2019. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Role and Effect of Anemia in Children With Pneumonia
- ClinicalTrials.gov ID
- NCT02466672
- Acronym / sponsor ID
- 2014P001325
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 212 participants (actual)
- Lead sponsor
- Massachusetts General HospitalUniversity, hospital or other
- Collaborators
- Mbarara University of Science and Technology, Thrasher Research Fund, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
- Study start
- Feb 2015
- Primary completion
- Jan 2016 (actual)
- Study completion
- Jan 2016 (actual)
- First posted
- 9 Jun 2015 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will measure the effect of anemia on the outcomes of hospitalized children with severe pneumonia.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 6 to 59 months
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
- Study population
- Children age 6 months to 59 months admitted to the hospital with WHO-defined severe pneumonia
Key inclusion criteria (2 listed)
- Age 6 months to 59 months
- WHO-defined severe pneumonia
Key exclusion criteria (1 listed)
- Congenital heart disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| none - observational only | Other | – |
Primary outcome
Time to recovery from pneumonia
Time frame: participants will be followed for the duration of hospital stay, an expected average of 5 days
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Jul 2019.
- Derived from this study: PubMed 41921770Moschovis PP, Sharfi A, Chaudhury S, Sharma A, Wiens MO, Kumbakumba E, Keneema O, Nyehengane D, Kabakyenga J, Ansermino JM, Kissoon N, Christiani DC, Dzik W, Kiwanuka JP, Hibberd PL. The Effect of Anemia on Mortality in Children Hospitalized with Severe Pneumonia in Uganda. J Pediatr. 2026 Jul;294:115090. doi: 10.1016/j.jpeds.2026.115090. Epub 2026 Mar 30.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Peter P Moschovis, MD principal investigator
Massachusetts General Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Anemia and Pneumonia, run by Massachusetts General Hospital at 1 site in Uganda.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Jul 2019. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Uganda. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Time to recovery from pneumonia (time frame: participants will be followed for the duration of hospital stay, an expected average of 5 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02466672, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Jul 2019.