Cardiac Arrest, SuddenNCT02473679
Influence of the Education in Layperson in Out of Hospital Resuscitation
An observational study of Cardiac Arrest, Sudden and Heart Arrest, run by University of Zurich at 1 site in Switzerland.
Trial summary
Cardiac arrest occurs frequently and the outcome after out-of-hospital resuscitation is often fatal. Disturbing is that more than half of the surviving patients suffer from permanent impairment of cognitive functions, such attention, memory and executive functioning. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Cardiac Arrest, Sudden, Heart Arrest
- How many people
- 1,662 participants
- Where
- 1 siteSwitzerland
- Study dates
- Jan 2003to Jul 2016
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Out of hospital patients suffered or suffering cardiac arrest, who were or will be resuscitated by laypersons, city police and/or trained emergency medical services teams who were called to the emergency
Who may be able to join
- All Out of hospital patients suffering cardiac arrest in Zurich City, resuscitated by lay persons, city police and or trained emergency medical services
Who cannot join
- individuals with cardiac arrest occurring in the presence of EMS
- individuals in whom there were apparent toxic, traumatic or suicidal etiologies for unconsciousness
- drowned individuals and individuals with terminal illness
- documented negation of data collection
Trial locations and contacts
1 site in 1 country.
Switzerland1 site
University Hospital Zurich
Zurich, Canton of Zurich, 8091
About this study
Official title: Influence of the Education in Layperson Resuscitation and Preparation the Patrol Car of the City Police With Automatic External Defibrillators and Automated Ventilation Equipment on Out of Hospital Resuscitation Outcome
Cardiac arrest occurs frequently and the outcome after out-of-hospital resuscitation is often fatal. Disturbing is that more than half of the surviving patients suffer from permanent impairment of cognitive functions, such attention, memory and executive functioning. With all the efforts to achieve a high quality initial resuscitation management the time delay between cardiac arrest and the beginning the initial resuscitation maneuver is the main reason for the still poor outcome. To shorten this fatal time delay, current efforts of national and supranational health authorities aime at the non-medically trained lay person, who should carry out basic life support directly on the scene supported by the use of public available semi-automatic defibrillators (AED).
Read the detailed description
It is a combined retrospective and prospective observational single center study. Data of all Out of Hospital patients suffered a cardiac arrest in Zurich city will be collected according to the Utstein criteria. The aim of this study is to investigate the impact of trained police forces in the resuscitation outcome.
- Conditions
- Cardiac Arrest, Sudden, Heart Arrest
- Keywords
- First Responder, BLS, AED, Resuscitation
- Medical subject headings
- Death, Sudden, Cardiac, Heart Arrest
What is being measured
The primary outcome is the main question the study is designed to answer.
Time line for restoration the circulation
Timeline for restoration the circulation after layperson started the reanimation
Measured: participants will be followed from origin of the event up to 12 month or death
Secondary outcomes (4)
Time interval to first shock ,
Time interval from the emergency call to first shock for ventricular fibrillation
Measured: participants will be followed from origin of the event up to 12 month or death
Neurologic outcome
Data will be collected according to Utstein criteria
Measured: participants will be followed from origin of the event for duration of hospital stay, follow up after 12 month or death
Time interval removal from ICU as well as discharged from hospital
Time interval up to the removal from ICU as well as duration of hospital stay
Measured: participants will be followed from origin of the event up to 12 month or death
Definitive survival rate
Survival rate of participants resuscitated by layperson after cardiac arrest
Measured: participants will be followed from origin of the event up to 12 month or death
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jun 2015 (estimated)
- Study startJan 2003
- Primary completionJul 2016
- Study completionJul 2016
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cardiac Arrest, SuddenStudies of the same condition, open and under way.
- More trials run by University of ZurichThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Enrolment
- 1,662 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Zurich
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Donat R Spahn, Prof, Principal investigator, IFA, University Hospital Zurich
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02473679
- Sponsor's protocol ID
- KEK2014 - 0665
- Status last verified
- Nov 2016
- First submitted
- 13 May 2015
- Last updated
- 2 Nov 2016
- Results posted
- No
- Data monitoring committee
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Nov 2016. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influence of the Education in Layperson Resuscitation and Preparation the Patrol Car of the City Police With Automatic External Defibrillators and Automated Ventilation Equipment on Out of Hospital Resuscitation Outcome
- ClinicalTrials.gov ID
- NCT02473679
- Acronym / sponsor ID
- KEK2014 - 0665
- Conditions
- Cardiac Arrest, Sudden, Heart Arrest
- Keywords
- First Responder, BLS, AED, Resuscitation
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 1,662 participants (actual)
- Lead sponsor
- University of ZurichUniversity, hospital or other
- Study start
- Jan 2003
- Primary completion
- Jul 2016 (actual)
- Study completion
- Jul 2016 (actual)
- First posted
- 16 Jun 2015 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Cardiac arrest occurs frequently and the outcome after out-of-hospital resuscitation is often fatal. Disturbing is that more than half of the surviving patients suffer from permanent impairment of cognitive functions, such attention, memory and executive functioning. With all the efforts to achieve a high quality initial resuscitation management the time delay between cardiac arrest and the beginning the initial resuscitation maneuver is the main reason for the still poor outcome. To shorten this fatal time delay, current efforts of national and supranational health authorities aime at the non-medically trained lay person, who should carry out basic life support directly on the scene supported by the use of public available semi-automatic defibrillators (AED).
Detailed description
It is a combined retrospective and prospective observational single center study. Data of all Out of Hospital patients suffered a cardiac arrest in Zurich city will be collected according to the Utstein criteria. The aim of this study is to investigate the impact of trained police forces in the resuscitation outcome.
Study design
- Observational model
- Cohort
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Out of hospital patients suffered or suffering cardiac arrest, who were or will be resuscitated by laypersons, city police and/or trained emergency medical services teams who were called to the emergency
Key inclusion criteria (1 listed)
- All Out of hospital patients suffering cardiac arrest in Zurich City, resuscitated by lay persons, city police and or trained emergency medical services
Key exclusion criteria (4 listed)
- individuals with cardiac arrest occurring in the presence of EMS
- individuals in whom there were apparent toxic, traumatic or suicidal etiologies for unconsciousness
- drowned individuals and individuals with terminal illness
- documented negation of data collection
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Time line for restoration the circulation
Time frame: participants will be followed from origin of the event up to 12 month or death
Timeline for restoration the circulation after layperson started the reanimation
4 secondary outcomes
Time interval to first shock ,
Time frame: participants will be followed from origin of the event up to 12 month or death
Neurologic outcome
Time frame: participants will be followed from origin of the event for duration of hospital stay, follow up after 12 month or death
Time interval removal from ICU as well as discharged from hospital
Time frame: participants will be followed from origin of the event up to 12 month or death
Definitive survival rate
Time frame: participants will be followed from origin of the event up to 12 month or death
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Nov 2016.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Donat R Spahn, Prof principal investigator
IFA, University Hospital Zurich
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cardiac Arrest, Sudden and Heart Arrest, run by University of Zurich at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Nov 2016. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Time line for restoration the circulation (time frame: participants will be followed from origin of the event up to 12 month or death). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Nov 2016.