Cardiopulmonary ResuscitationNCT02715180
Optimum Hand Position During Cardiopulmonary Resuscitation
A study testing low dose chest computed tomography in people with Cardiopulmonary Resuscitation and Hand Position, run by Seoul National University Bundang Hospital.
Trial summary
The almost evidences of the optimal hand position during compression had been based on chest computed tomography (CT) or chest plain films of patients for investigating the effective location for compressing the left ventricle of the heart during cardiopulmonary resuscitation (CPR). Read more about this study
- Who is it for?
- Ages 19 years and olderHealthy volunteers can take part
- Conditions the study is for
- Cardiopulmonary Resuscitation, Hand Position
- What is being tested?
- low dose chest computed tomography
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 127 participants
- Where
- No sites listed yet
- Study dates
- Aug 2015to Dec 2015
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 19 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- over 18 years of age
- no history of heart or lung disease
- no history of chest or abdominal surgery
Who cannot join
- abnormal findings in LDCT, which might influence inspiration or expiration, were excluded after image interpretation by the board certified radiologists
About this study
Official title: Optimum Hand Position During Cardiopulmonary Resuscitation: Comparing Expiration and Inspiration View of the Scout Film of the Low Dose Chest Computed Tomography
The almost evidences of the optimal hand position during compression had been based on chest computed tomography (CT) or chest plain films of patients for investigating the effective location for compressing the left ventricle of the heart during cardiopulmonary resuscitation (CPR).
However every study was conducted at full inspired state of respiration. A prospective cohort study to evaluate the proper hand position during CPR based on expired respiratory state CT as the health screening would be needed.
- Conditions
- Cardiopulmonary Resuscitation, Hand Position
- Being tested
- low dose chest computed tomography
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
low dose chest computed tomographyRadiation
All participants were evaluated 2 scout films during LDCT screenings. The first scout film was obtained while a participant was holding a comfortable expiration with the arms at down position, and the second scout film was obtained while a full inspiration with the arms at raised position. The axial images of LDCT were taken during participants' full inspiration. The radio-opaque marker was attached to the participants' skin where the lowest part of sternum was palpable, because the sternum moves according to the position of arms and respiration.
| Study group | Role | What they receive |
|---|---|---|
| Chest computed tomography | Other | Low dose chest computed tomography during expiration and inspiration Receives: Radiation: low dose chest computed tomography |
What is being measured
The primary outcome is the main question the study is designed to answer.
proper hand position during CPR using the scout film of low dose chest computed tomography
proper hand position during CPR based on comparison between expiration with the arms at down position and inspiration the arms at raised position.
Measurement will be assessed with a length of xiphoid process to arbitrary center of heart
Measured: five months
Secondary outcomes (1)
predicted compressed organs in CPR using the scout film of low dose chest computed tomography Measurement will be assessed with scout film silhouette of organs under quarterly divided sternum.
Measured: five months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Mar 2016 (estimated)
- Study startAug 2015
- Primary completionDec 2015
- Study completionDec 2015
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (7)Papers the sponsor has linked to this study.
- Other trials for Cardiopulmonary ResuscitationStudies of the same condition, open and under way.
- More trials run by Seoul National University Bundang HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 127 participants (actual)
Sponsor and investigators
- Lead sponsor
- Seoul National University Bundang Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hyuksool Kwon, Seoul National University Bundang Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02715180
- Sponsor's protocol ID
- Hear_position_01
- Status last verified
- Apr 2018
- First submitted
- 14 Mar 2016
- Last updated
- 18 Apr 2018
- Results posted
- No
- Data monitoring committee
- No
- Individual data sharing
- No
Publications
Klouche K, Weil MH, Sun S, Tang W, Povoas H, Bisera J. Stroke volumes generated by precordial compression during cardiac resuscitation. Crit Care Med. 2002 Dec;30(12):2626-31. doi: 10.1097/00003246-200212000-00002.
PubMed 12483049Perkins GD, Handley AJ, Koster RW, Castren M, Smyth MA, Olasveengen T, Monsieurs KG, Raffay V, Grasner JT, Wenzel V, Ristagno G, Soar J; Adult basic life support and automated external defibrillation section Collaborators. European Resuscitation Council Guidelines for Resuscitation 2015: Section 2. Adult basic life support and automated external defibrillation. Resuscitation. 2015 Oct;95:81-99. doi: 10.1016/j.resuscitation.2015.07.015. Epub 2015 Oct 15. No abstract available.
PubMed 26477420Travers AH, Perkins GD, Berg RA, Castren M, Considine J, Escalante R, Gazmuri RJ, Koster RW, Lim SH, Nation KJ, Olasveengen TM, Sakamoto T, Sayre MR, Sierra A, Smyth MA, Stanton D, Vaillancourt C; Basic Life Support Chapter Collaborators. Part 3: Adult Basic Life Support and Automated External Defibrillation: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation. 2015 Oct 20;132(16 Suppl 1):S51-83. doi: 10.1161/CIR.0000000000000272.
PubMed 26472859Cha KC, Kim HJ, Shin HJ, Kim H, Lee KH, Hwang SO. Hemodynamic effect of external chest compressions at the lower end of the sternum in cardiac arrest patients. J Emerg Med. 2013 Mar;44(3):691-7. doi: 10.1016/j.jemermed.2012.09.026. Epub 2012 Dec 4.
PubMed 23218197Qvigstad E, Kramer-Johansen J, Tomte O, Skalhegg T, Sorensen O, Sunde K, Olasveengen TM. Clinical pilot study of different hand positions during manual chest compressions monitored with capnography. Resuscitation. 2013 Sep;84(9):1203-7. doi: 10.1016/j.resuscitation.2013.03.010. Epub 2013 Mar 15.
PubMed 23499897Orlowski JP. Optimum position for external cardiac compression in infants and young children. Ann Emerg Med. 1986 Jun;15(6):667-73. doi: 10.1016/s0196-0644(86)80423-1.
PubMed 3706857Pickard A, Darby M, Soar J. Radiological assessment of the adult chest: implications for chest compressions. Resuscitation. 2006 Dec;71(3):387-90. doi: 10.1016/j.resuscitation.2006.04.012. Epub 2006 Sep 18.
PubMed 16982125
Study at a glance
From the registry record, last updated by the sponsor on 18 Apr 2018. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Optimum Hand Position During Cardiopulmonary Resuscitation: Comparing Expiration and Inspiration View of the Scout Film of the Low Dose Chest Computed Tomography
- ClinicalTrials.gov ID
- NCT02715180
- Acronym / sponsor ID
- Hear_position_01
- Conditions
- Cardiopulmonary Resuscitation, Hand Position
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 127 participants (actual)
- Lead sponsor
- Seoul National University Bundang HospitalUniversity, hospital or other
- Study start
- Aug 2015
- Primary completion
- Dec 2015 (actual)
- Study completion
- Dec 2015 (actual)
- First posted
- 22 Mar 2016 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The almost evidences of the optimal hand position during compression had been based on chest computed tomography (CT) or chest plain films of patients for investigating the effective location for compressing the left ventricle of the heart during cardiopulmonary resuscitation (CPR).
However every study was conducted at full inspired state of respiration. A prospective cohort study to evaluate the proper hand position during CPR based on expired respiratory state CT as the health screening would be needed.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Chest computed tomography | Other | Radiation: low dose chest computed tomographyLow dose chest computed tomography during expiration and inspiration |
Who may qualify
- Ages
- 19 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- over 18 years of age
- no history of heart or lung disease
- no history of chest or abdominal surgery
Key exclusion criteria (1 listed)
- abnormal findings in LDCT, which might influence inspiration or expiration, were excluded after image interpretation by the board certified radiologists
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| low dose chest computed tomographyAll participants were evaluated 2 scout films during LDCT screenings. The first scout film was obtained while a participant was holding a comfortable expiration with the arms at down position, and the second scout film was obtained while a full inspiration with the arms at raised position. The axial images of LDCT were taken during participants' full inspiration. The radio-opaque marker was attached to the participants' skin where the lowest part of sternum was palpable, because the sternum moves according to the position of arms and respiration. | Radiation | Chest computed tomography |
Primary outcome
proper hand position during CPR using the scout film of low dose chest computed tomography
Time frame: five months
proper hand position during CPR based on comparison between expiration with the arms at down position and inspiration the arms at raised position. Measurement will be assessed with a length of xiphoid process to arbitrary center of heart
1 secondary outcome
predicted compressed organs in CPR using the scout film of low dose chest computed tomography Measurement will be assessed with scout film silhouette of organs under quarterly divided sternum.
Time frame: five months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Apr 2018.
- Background: PubMed 12483049Klouche K, Weil MH, Sun S, Tang W, Povoas H, Bisera J. Stroke volumes generated by precordial compression during cardiac resuscitation. Crit Care Med. 2002 Dec;30(12):2626-31. doi: 10.1097/00003246-200212000-00002.
- Background: PubMed 26477420Perkins GD, Handley AJ, Koster RW, Castren M, Smyth MA, Olasveengen T, Monsieurs KG, Raffay V, Grasner JT, Wenzel V, Ristagno G, Soar J; Adult basic life support and automated external defibrillation section Collaborators. European Resuscitation Council Guidelines for Resuscitation 2015: Section 2. Adult basic life support and automated external defibrillation. Resuscitation. 2015 Oct;95:81-99. doi: 10.1016/j.resuscitation.2015.07.015. Epub 2015 Oct 15. No abstract available.
- Background: PubMed 26472859Travers AH, Perkins GD, Berg RA, Castren M, Considine J, Escalante R, Gazmuri RJ, Koster RW, Lim SH, Nation KJ, Olasveengen TM, Sakamoto T, Sayre MR, Sierra A, Smyth MA, Stanton D, Vaillancourt C; Basic Life Support Chapter Collaborators. Part 3: Adult Basic Life Support and Automated External Defibrillation: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation. 2015 Oct 20;132(16 Suppl 1):S51-83. doi: 10.1161/CIR.0000000000000272.
- Background: PubMed 23218197Cha KC, Kim HJ, Shin HJ, Kim H, Lee KH, Hwang SO. Hemodynamic effect of external chest compressions at the lower end of the sternum in cardiac arrest patients. J Emerg Med. 2013 Mar;44(3):691-7. doi: 10.1016/j.jemermed.2012.09.026. Epub 2012 Dec 4.
- Background: PubMed 23499897Qvigstad E, Kramer-Johansen J, Tomte O, Skalhegg T, Sorensen O, Sunde K, Olasveengen TM. Clinical pilot study of different hand positions during manual chest compressions monitored with capnography. Resuscitation. 2013 Sep;84(9):1203-7. doi: 10.1016/j.resuscitation.2013.03.010. Epub 2013 Mar 15.
- Background: PubMed 3706857Orlowski JP. Optimum position for external cardiac compression in infants and young children. Ann Emerg Med. 1986 Jun;15(6):667-73. doi: 10.1016/s0196-0644(86)80423-1.
- Background: PubMed 16982125Pickard A, Darby M, Soar J. Radiological assessment of the adult chest: implications for chest compressions. Resuscitation. 2006 Dec;71(3):387-90. doi: 10.1016/j.resuscitation.2006.04.012. Epub 2006 Sep 18.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing low dose chest computed tomography in people with Cardiopulmonary Resuscitation and Hand Position, run by Seoul National University Bundang Hospital.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 18 Apr 2018. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
proper hand position during CPR using the scout film of low dose chest computed tomography (time frame: five months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02715180, which also lists 7 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Apr 2018.