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Coronary ArteriesMAIN COMPARENCT02791412

Ten-Year Outcomes of Stents Versus Coronary-Artery Bypass Grafting for Left Main Coronary Artery Disease

An observational study of Coronary Arteries, run by Seung-Jung Park at 12 sites in South Korea.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The purpose of this study is to evaluate long-term outcome of treatment(percutaneous coronary intervention or coronary-artery bypass graft) in unprotected left main coronary artery stenosis in Korea. Read more about this study

Who is it for?
Ages 19 years and older
Conditions the study is for
Coronary Arteries
What is being tested?
percutaneous coronary intervention or coronary-artery bypass graft
Type of treatment
Surgery or procedure
How many people
2,240 participants
Where
12 sitesSouth Korea
Study dates
13 Jan 2017to 30 May 2018
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 19 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: Patients undergone percutaneous coronary intervention or coronary-artery bypass graft for treatment of unprotected left main disease

Who may be able to join

  • Unprotected left main disease

Who cannot join

  • No exclusion criteria

Trial locations and contacts

12 sites in 1 country.

12 sites in 1 country

South Korea12 sites

  • Kyungpook National University Hospital

    Daegu

  • Chungnam National University Hospital

    Daejeon

  • Chonnam National University Hospital

    Gwangju

  • Gachon University Gil Hospital

    Incheon

  • Asan Medical Center

    Seoul, Songpa-gu, 138-736

  • Samsung Medical Center

    Seoul

  • Seoul National University Hospital

    Seoul

  • Severance Hospital

    Seoul

  • The Catholic University of Korea Seoul St. Mary's Hospital

    Seoul

  • The Catholic University of Korea, Yeouido St. Mary's Hospital

    Seoul

  • Seoul National University Bundang hospital

    Sungnam

  • Ajou University Hospital

    Suwon

Other trials in South Korea

About this study

Official title: Ten-Year Outcomes of Stents Versus Coronary-Artery Bypass Grafting for Left Main Coronary Artery Disease in Korea : Multicenter, Long-term, Observational Trial

The purpose of this study is to evaluate long-term outcome of treatment(percutaneous coronary intervention or coronary-artery bypass graft) in unprotected left main coronary artery stenosis in Korea.

Being tested
percutaneous coronary intervention or coronary-artery bypass graft
Keywords
left main, unprotected, percutaneous coronary intervention, coronary-artery bypass graft

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • percutaneous coronary intervention or coronary-artery bypass graftProcedure or surgery

Study groups in NCT02791412
Study groupRoleWhat they receive
unprotected left mainundergone percutaneous coronary intervention or coronary artery bypass graft
Receives: Procedure: percutaneous coronary intervention or coronary-artery bypass graft

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. composite event

    all-cause death, myocardiac infarction, revascularization

    Measured: 10 years

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted6 Jun 2016 (estimated)
  2. Study start13 Jan 2017
  3. Primary completion30 May 2018
  4. Study completion30 May 2018

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Retrospective
Enrolment
2,240 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT02791412
Sponsor's protocol ID
AMCCV2016-08
Acronym
MAIN COMPARE
Status last verified
Jun 2018
First submitted
30 May 2016
Last updated
26 Jun 2018
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: This is not a publicly funded trial.

Publications

  • Kim TO, Kang DY, Ahn JM, Kim MJ, Lee PH, Kim H, Choi Y, Lee J, Lee JM, Jo HH, Park YS, Lim SM, Park SJ, Park DW. Impact of Target Lesion Revascularization on Long-Term Mortality After Percutaneous Coronary Intervention for Left Main Disease. JACC Cardiovasc Interv. 2024 Jan 8;17(1):32-42. doi: 10.1016/j.jcin.2023.10.068.

    PubMed 38199751

  • Yoon YH, Ahn JM, Lee JB, Kang DY, Park H, Jeong YJ, Lee J, Kim JH, Yang Y, Hyun J, Lee PH, Park DW, Park SJ. Time-Dependent Impact of Sex on the Long-Term Outcomes After Left Main Revascularization. J Am Heart Assoc. 2022 Mar;11(5):e021720. doi: 10.1161/JAHA.121.021720. Epub 2022 Feb 22.

    PubMed 35189706

  • Kang DY, Ahn JM, Yun SC, Park H, Cho SC, Kim TO, Park S, Lee PH, Lee SW, Park SW, Park DW, Park SJ. Long-Term Clinical Impact of Intravascular Ultrasound Guidance in Stenting for Left Main Coronary Artery Disease. Circ Cardiovasc Interv. 2021 Oct;14(10):e011011. doi: 10.1161/CIRCINTERVENTIONS.121.011011. Epub 2021 Oct 19.

    PubMed 34665659

  • Lee K, Ahn JM, Yoon YH, Kang DY, Park SY, Ko E, Park H, Cho SC, Park S, Kim TO, Lee PH, Lee SW, Park SW, Park DW, Park SJ. Long-Term (10-Year) Outcomes of Stenting or Bypass Surgery for Left Main Coronary Artery Disease in Patients With and Without Diabetes Mellitus. J Am Heart Assoc. 2020 Apr 21;9(8):e015372. doi: 10.1161/JAHA.119.015372. Epub 2020 Apr 20.

    PubMed 32310027

  • Kim TO, Ahn JM, Kang DY, Kim SO, Park S, Park H, Lee PH, Lee SW, Park SW, Park DW, Park SJ. Rates and Independent Correlates of 10-Year Major Adverse Events and Mortality in Patients Undergoing Left Main Coronary Arterial Revascularization. Am J Cardiol. 2020 Apr 15;125(8):1148-1153. doi: 10.1016/j.amjcard.2020.01.023. Epub 2020 Jan 29.

    PubMed 32085865

  • Yoon YH, Ahn JM, Kang DY, Park H, Cho SC, Lee PH, Lee SW, Park SW, Park DW, Park SJ. Impact of SYNTAX Score on 10-Year Outcomes After Revascularization for Left Main Coronary Artery Disease. JACC Cardiovasc Interv. 2020 Feb 10;13(3):361-371. doi: 10.1016/j.jcin.2019.10.020.

    PubMed 32029254

  • Park DW, Ahn JM, Yun SC, Yoon YH, Kang DY, Lee PH, Lee SW, Park SW, Seung KB, Gwon HC, Jeong MH, Jang Y, Kim HS, Seong IW, Park HS, Ahn T, Chae IH, Tahk SJ, Park SJ. 10-Year Outcomes of Stents Versus Coronary Artery Bypass Grafting for Left Main Coronary Artery Disease. J Am Coll Cardiol. 2018 Dec 11;72(23 Pt A):2813-2822. doi: 10.1016/j.jacc.2018.09.012. Epub 2018 Sep 24.

    PubMed 30261236

Questions about this trial

What is this clinical trial studying?

An observational study of Coronary Arteries, run by Seung-Jung Park at 12 sites in South Korea.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 26 Jun 2018. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 12 sites in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

composite event (time frame: 10 years). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT02791412, which also lists 7 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jun 2018.

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