NeuropsychologyGeSTWoMNCT02859649
Gestural Short Term and Working Memory Task
A study testing neuropsychological test in people with Neuropsychology and Gesture, run by Centre Hospitalier Universitaire de Besancon at 1 site in France.
Trial summary
According to the working memory model, which accounts for the organisation of working memory, the processing of non-meaningful gestures is not clear. Some authors suggest that working memory for non-meaningful gestures has the same characteristics as the phonological loop, made up of a phonological store and of a… Read more about this study
- Who is it for?
- Ages 18 to 50 yearsHealthy volunteers can take part
- Conditions the study is for
- Neuropsychology, Gesture
- What is being tested?
- neuropsychological test
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteFrance
- Study dates
- Apr 2016to Oct 2016
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- healthy adult volunteers
- 18/50 years old
- they must speak fluent French and give their informed consent
Who cannot join
- neurological or psychiatric disorder
- uncorrected visual or hearing loss
Trial locations and contacts
1 site in 1 country.
About this study
According to the working memory model, which accounts for the organisation of working memory, the processing of non-meaningful gestures is not clear. Some authors suggest that working memory for non-meaningful gestures has the same characteristics as the phonological loop, made up of a phonological store and of a revival process (articulatory rehearsal). These characteristics are evidenced in memory span tasks, memory span which is itself determined by the duration of the memory trace and the time required to refresh the trace by subvocal rehearsal.
The investigators therefore aim to set up a gestural working memory task, which is specific, simple and reproducible, in the manner of verbal and visuospatial span tasks. It will first be an exploratory and descriptive study with healthy subjects.
Read the detailed description
In the first instance, each subject performs the gestural working memory test. The test is based on the model of verbal or visuospatial working memory tests. Video clips that display the movement of two, then three, then four different fingers are shown to the subject, who must then reproduce them. There are nine different sub-tests: forward span and backward span for both hands then for each hand, i.e. six sub-tests, in addition to three sub-tests with concomitant interference tasks (verbal, gestural or both). Each sub-test comes to an end when the subject fails both attempts of the same item. The entire test takes approximately 30 minutes.
A questionnaire is then handed to the subject: the subject provides their full name, date of birth, profession, education level (number of years of study post compulsory education), laterality, as well as potential professional or leisure activities that might involve fine finger movement. They also complete the Edinburgh Handedness Inventory assessment.
In order to correlate this new test with other validated tasks, each subject is then required to perform a verbal and visuospatial working memory task: the digit span test and then the spatial memory test, which last approximately 10 minutes.
The entire protocol lasts approximately 45 minutes per subject. The data is then anonymized and processed confidentially.
- Conditions
- Neuropsychology, Gesture
- Being tested
- neuropsychological test
- Keywords
- working memory, short term memory, gesture
- Medical subject headings
- Gestures
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
neuropsychological testBehavioural
neuropsychological test
| Study group | Role | What they receive |
|---|---|---|
| healthy volunteers | Experimental | Not described Receives: Behavioral: neuropsychological test |
What is being measured
The primary outcome is the main question the study is designed to answer.
Gestural span
Measure and description of the gestural span during the tests of short-term memory and gestural working memory, and correlation with the verbal and visuo-spatial spans.
Measured: 1 day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Aug 2016 (estimated)
- Study startApr 2016
- Primary completionJul 2016
- Study completionOct 2016 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (6)Papers the sponsor has linked to this study.
- Other trials for NeuropsychologyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire de Besancon
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02859649
- Sponsor's protocol ID
- P/2016/283
- Acronym
- GeSTWoM
- Status last verified
- Aug 2016
- First submitted
- 14 Apr 2016
- Last updated
- 9 Aug 2016
- Results posted
- No
- Data monitoring committee
- No
Publications
Baddeley A. The episodic buffer: a new component of working memory? Trends Cogn Sci. 2000 Nov 1;4(11):417-423. doi: 10.1016/s1364-6613(00)01538-2.
PubMed 11058819Baddeley AD, Allen RJ, Hitch GJ. Binding in visual working memory: the role of the episodic buffer. Neuropsychologia. 2011 May;49(6):1393-400. doi: 10.1016/j.neuropsychologia.2010.12.042. Epub 2011 Jan 20.
PubMed 21256143Wilson M, Fox G. Working memory for language is not special: evidence for an articulatory loop for novel stimuli. Psychon Bull Rev. 2007 Jun;14(3):470-3. doi: 10.3758/bf03194091.
PubMed 17874590Conway AR, Kane MJ, Bunting MF, Hambrick DZ, Wilhelm O, Engle RW. Working memory span tasks: A methodological review and user's guide. Psychon Bull Rev. 2005 Oct;12(5):769-86. doi: 10.3758/bf03196772.
PubMed 16523997Cowan N. The magical number 4 in short-term memory: a reconsideration of mental storage capacity. Behav Brain Sci. 2001 Feb;24(1):87-114; discussion 114-85. doi: 10.1017/s0140525x01003922.
PubMed 11515286CONRAD R, HULL AJ. INFORMATION, ACOUSTIC CONFUSION AND MEMORY SPAN. Br J Psychol. 1964 Nov;55:429-32. doi: 10.1111/j.2044-8295.1964.tb00928.x. No abstract available.
PubMed 14237884
Study at a glance
From the registry record, last updated by the sponsor on 9 Aug 2016. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Gestural Short Term and Working Memory Task
- ClinicalTrials.gov ID
- NCT02859649
- Acronym / sponsor ID
- GeSTWoM / P/2016/283
- Conditions
- Neuropsychology, Gesture
- Keywords
- working memory, short term memory, gesture
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Centre Hospitalier Universitaire de BesanconUniversity, hospital or other
- Study start
- Apr 2016
- Primary completion
- Jul 2016 (actual)
- Study completion
- Oct 2016 (estimated)
- First posted
- 9 Aug 2016 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
According to the working memory model, which accounts for the organisation of working memory, the processing of non-meaningful gestures is not clear. Some authors suggest that working memory for non-meaningful gestures has the same characteristics as the phonological loop, made up of a phonological store and of a revival process (articulatory rehearsal). These characteristics are evidenced in memory span tasks, memory span which is itself determined by the duration of the memory trace and the time required to refresh the trace by subvocal rehearsal.
The investigators therefore aim to set up a gestural working memory task, which is specific, simple and reproducible, in the manner of verbal and visuospatial span tasks. It will first be an exploratory and descriptive study with healthy subjects.
Detailed description
In the first instance, each subject performs the gestural working memory test. The test is based on the model of verbal or visuospatial working memory tests. Video clips that display the movement of two, then three, then four different fingers are shown to the subject, who must then reproduce them. There are nine different sub-tests: forward span and backward span for both hands then for each hand, i.e. six sub-tests, in addition to three sub-tests with concomitant interference tasks (verbal, gestural or both). Each sub-test comes to an end when the subject fails both attempts of the same item. The entire test takes approximately 30 minutes.
A questionnaire is then handed to the subject: the subject provides their full name, date of birth, profession, education level (number of years of study post compulsory education), laterality, as well as potential professional or leisure activities that might involve fine finger movement. They also complete the Edinburgh Handedness Inventory assessment.
In order to correlate this new test with other validated tasks, each subject is then required to perform a verbal and visuospatial working memory task: the digit span test and then the spatial memory test, which last approximately 10 minutes.
The entire protocol lasts approximately 45 minutes per subject. The data is then anonymized and processed confidentially.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| healthy volunteers | Experimental | Behavioral: neuropsychological test |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- healthy adult volunteers
- 18/50 years old
- they must speak fluent French and give their informed consent
Key exclusion criteria (2 listed)
- neurological or psychiatric disorder
- uncorrected visual or hearing loss
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| neuropsychological testneuropsychological test | Behavioural | healthy volunteers |
Primary outcome
Gestural span
Time frame: 1 day
Measure and description of the gestural span during the tests of short-term memory and gestural working memory, and correlation with the verbal and visuo-spatial spans.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Aug 2016.
- Background: PubMed 11058819Baddeley A. The episodic buffer: a new component of working memory? Trends Cogn Sci. 2000 Nov 1;4(11):417-423. doi: 10.1016/s1364-6613(00)01538-2.
- Background: PubMed 21256143Baddeley AD, Allen RJ, Hitch GJ. Binding in visual working memory: the role of the episodic buffer. Neuropsychologia. 2011 May;49(6):1393-400. doi: 10.1016/j.neuropsychologia.2010.12.042. Epub 2011 Jan 20.
- Background: PubMed 17874590Wilson M, Fox G. Working memory for language is not special: evidence for an articulatory loop for novel stimuli. Psychon Bull Rev. 2007 Jun;14(3):470-3. doi: 10.3758/bf03194091.
- Background: PubMed 16523997Conway AR, Kane MJ, Bunting MF, Hambrick DZ, Wilhelm O, Engle RW. Working memory span tasks: A methodological review and user's guide. Psychon Bull Rev. 2005 Oct;12(5):769-86. doi: 10.3758/bf03196772.
- Background: PubMed 11515286Cowan N. The magical number 4 in short-term memory: a reconsideration of mental storage capacity. Behav Brain Sci. 2001 Feb;24(1):87-114; discussion 114-85. doi: 10.1017/s0140525x01003922.
- Background: PubMed 14237884CONRAD R, HULL AJ. INFORMATION, ACOUSTIC CONFUSION AND MEMORY SPAN. Br J Psychol. 1964 Nov;55:429-32. doi: 10.1111/j.2044-8295.1964.tb00928.x. No abstract available.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing neuropsychological test in people with Neuropsychology and Gesture, run by Centre Hospitalier Universitaire de Besancon at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 9 Aug 2016. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Gestural span (time frame: 1 day). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02859649, which also lists 6 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Aug 2016.