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Stroke, AcuteAVC-endovascNCT02879123

Early Neurological Clinical Recovery, 3 Months After Endovascular Treatment of an Acute Ischemic Stroke

An observational study of Stroke, Acute, run by Fondation Ophtalmologique Adolphe de Rothschild at 1 site in France.

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Official record

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Trial summary

This trial aims at collecting standardized data concerning the early neurological clinical recovery of patients, 3 months after endovascular treatment of an acute ischemic stroke. Although this outcome is a major issue of patients' prognosis, it is rarely collected at this stage of their follow-up. Read more about this study

Who is it for?
Any age
Conditions the study is for
Stroke, Acute
How many people
5,000 participants
Where
1 siteFrance
Study dates
12 Nov 2015to 12 May 2031
Phase
Observational

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages Any age
  • All sexes
  • No healthy volunteers
  • Child, Adult, Older adult

Study population: patients undergoing endovascular treatment for an acute ischemic stroke

Who may be able to join

  • acute ischemic stroke
  • endovascular treatment

Who cannot join

  • none

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Raphaël Blanc, MD contact

+ 33 01 48 03 68 28

rblanc@for.paris

Amélie Yavchitz, MD contact

+33 01 48 03 64 54

ayavchitz@for.paris

France1 site, 1 recruiting
  • Fondation Ophtalmologique Adolphe de Rothschild

    Paris, 75019

    Patrick Vachey, ADM, +33 1 48 03 64 33, pvachey@for.paris

    Raphaël Blanc, MD

    Recruiting

Other trials in France

About this study

Official title: Assessment of Patients' Early Neurological Clinical Recovery, 3 Months After Endovascular Treatment of an Acute Ischemic Stroke

This trial aims at collecting standardized data concerning the early neurological clinical recovery of patients, 3 months after endovascular treatment of an acute ischemic stroke.

Although this outcome is a major issue of patients' prognosis, it is rarely collected at this stage of their follow-up.

Read the detailed description

Stroke affects 1 patient every 4 minutes in France, with around 130,000 new patients each year. Early recanalisation is a major prognostic factor and the main therapeutic target in the acute phase of this disease. The recanalisation techniques currently developed are intravenous thrombolysis, intra-arterial thrombolysis and thrombectomy (or embolectomy). These therapies can be combined. Thrombectomy involves endovascular capture of the clot obstructing the intracranial artery.

Recent improvements in thrombectomy techniques have also contributed to the spread of this technique. Neurovascular units include endovascular treatment in their strategy for the early management of acute proximal occlusions of intracranial arteries in almost 1 in 3 cases. This approach is currently the subject of professional agreements. Mechanical thrombectomy has now been validated by studies showing a major reduction (-35%) in the disability associated with severe cerebral infarction and a reduction in mortality, with recanalisation rates ranging from 58 to 72%. This "recanalisation" criterion is of major importance because it largely determines the functional prognosis of patients following a cerebral infarction.

Patients are often followed up in the months following the operation by the neurology department that initially treated them, and in the first few weeks they may be admitted to follow-up care units. As a result, although the clinical outcome at 3 months is a major factor in patient prognosis, this information is rarely available. The aim of this study is to obtain standardised 3-month follow-up data for a large series of patients who have undergone endovascular treatment for stroke.

Conditions
Stroke, Acute
Medical subject headings
Stroke

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. early neurological clinical recovery

    modified RANKIN score

    Measured: 3 months after endovascular treatment of an acute ischemic stroke

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted25 Aug 2016 (estimated)
  2. Study start12 Nov 2015
  3. Primary completion12 Nov 2030 (estimated)
  4. Study completion12 May 2031 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Other
Time perspective
Prospective
Enrolment
5,000 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT02879123
Sponsor's protocol ID
RBC_2015_19
Acronym
AVC-endovasc
Status last verified
Jan 2026
First submitted
22 Aug 2016
Last updated
22 Jan 2026
Results posted
No

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