Dry EyeNCT02925884
Effects of Gunnar Computer Glasses on Viewing Comfort and Performance
A study testing Gunnar OTC Glasses in people with Dry Eye and Eye Strain, run by Pacific University at 1 site in United States.
Trial summary
The proposed study aims to test if Gunnar computer glasses provide any advantages, in comparison to no glasses, on the following aspects in computer-related office work: Any enhancement on the visual performance of the basic visual function, including visual acuity, contrast sensitivity, color discrimination, etc. Read more about this study
- Who is it for?
- Ages 18 to 42 yearsHealthy volunteers can take part
- Conditions the study is for
- Dry Eye, Eye Strain, Visual Acuity
- What is being tested?
- Gunnar OTC Glasses
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 35 participants
- Where
- 1 siteUnited States
- Study dates
- Jun 2013to Sep 2013
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 42 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Subjects must be between 18 to 42 years old.
- Subjects must have a normal color vision (be able to identify the numbers in the color blind test.
- Subjects' near and far visual acuity with the better eye needs to be 20/25 or better (measured with a vision chart). Subjects can wear contact lenses (but not glasses) if usually wear them while working on computers.
- Subjects must routinely work on a computer or digital display for an average of 4 hours or more each day.
- Subjects can communicate in English fluently and are used to read English documents on a computer.
- Subjects must have a valid tax number or social security number to receive monetary compensation.
Who cannot join
- The difference in the prescription for both eyes is equal to or larger than 2 Diopters.
- Subjects have a cataract or have had cataract surgery.
- Subjects are sensitive to lights (photosensitivity).
- Subjects have prior incidents or are known to have claustrophobia.
- Subjects have been diagnosed with oculomotor diseases or central nervous system diseases, or with developmental, neurological, or psychiatric disorders (e.g., attention deficit hyperactivity disorder, autism, mental retardation).
Trial locations and contacts
1 site in 1 country.
United States1 site
Vision Performance Institute, 129 Scott Hall, Pacific University
Forest Grove, Oregon, 97116
About this study
Official title: The Effect of Computer Eyewear on Viewing Comfort and Performance in Office Work
The proposed study aims to test if Gunnar computer glasses provide any advantages, in comparison to no glasses, on the following aspects in computer-related office work:
- Any enhancement on the visual performance of the basic visual function, including visual acuity, contrast sensitivity, color discrimination, etc.
- Any enhancement on the visual performance of typical office work, including reading, word-spelling check, number searching, or target identification.
- Any benefit in objective viewing comfort measured with viewing distance, blink frequency, post-viewing pupil size.
- Any benefit in subjective viewing comfort reflected on the questionnaire of viewing symptom survey.
- Any benefit in viewing comfort and visual performance with increased environmental ventilation or under the strong glare.
- Any benefit in life quality from daily wearing (e.g., better comfort or sleep quality).
Read the detailed description
<Introduction>
When performing near work, one must focus at (accommodate) and point toward (converge) at a closer distance and constantly re-focus the eyes to see small text and images with clarity. Sustaining such efforts can lead to eye fatigue and eye strain, among a host of vision problems. Most visual tasks on a screen also demand heightened visual concentration, and this decreases blink rate. Working in a heated or air-conditioned office environment leads to over-evaporation of the tear film, and lipid deficiency, irritation, and dryness to the corneal surface are expected. Disruptive glare from excessive screen reflection and ambient lighting also deteriorates the image quality and heaps on viewing discomfort. Extensive screen viewing also exacerbates discomfort in people with existing vision problems like eye muscle imbalance, astigmatism, farsightedness, and presbyopia. Since technology is almost unavoidable to modern life, preventions should be taken to lessen the total toll on the eyes and visual system. Gunnar computer glasses address the above issues by providing mild yellow tint anti-reflection coating to shield the harmful blue light and lessen strong glare. The glasses also have a small amount of magnification (+0.5 D) to enhance acuity. The curved frame is designed to retain moisture and reduce dry eye symptoms. All these special characters are devised to enhance visual performance and minimize eye fatigue and visual discomfort in digital viewing. The current study aimed to validate the benefits mentioned above.
Gunnar over-the-counter (OTC) computer glasses adopt yellow lenses to cut off the active short wavelength and lessen the bright glare, which often induces the detrimental effect caused by excessive illumination or intense scattered reflection. While the benefit of glare reduction is well received, the benefit on visual performance has been inconclusive. Some studies reported a significant enhancement in contrast sensitivity, but some failed to see any improvement in visual acuity and contrast sensitivity, even with color distortion. Without argument, tinted lenses reduce the transmittance of the visible spectrum and change the visible color to a certain degree. However, there has been a report that reducing the retinal illumination level does not necessarily lead to reduced brightness; instead, the visual system automatically adjusts for the illumination discounting, possibly with the help of increased pupil size. In addition, with the decrement of blue lights arriving at the eyes, both scattered reflection and chromatic aberration are reduced. Together, it is reasonable to believe that the visual acuity, contrast sensitivity, and chromatic discrimination will not suffer and may, instead, benefit from the filter of yellow lenses. These basic visual functions may, in turn, lead to enhancement in general visual performance such as routine office work. These will be tested in the proposed study.
The current study tested if Gunnar's OTC computer glasses provide any advantages, in comparison to no glasses, on the following aspects in computer-related office work:
- Any enhancement on the visual performance of the basic visual function, including visual acuity, contrast sensitivity, color discrimination, etc.
- Any enhancement on the visual performance of typical office work, including reading, word-spelling check, number searching, or target identification.
- Any benefit in preventing dry eye by measuring the humidity outside and inside the frame (only in the visit with Gunnar glasses) and the tear film break-up time after viewing for a prolonged period.
- Any benefit in objective viewing comfort measured with viewing distance, blink frequency, post-viewing pupil size.
- Any benefit in subjective viewing comfort reflected on the questionnaire of viewing symptom survey.
- Any benefit in viewing comfort and visual performance with increased environmental ventilation.
- Any benefit in viewing comfort and visual performance with increased environment under the intense glare.
- Any benefit in life quality from daily wearing (e.g., viewing comfort, sleep quality, or quantity due to the amount of stimulation from blue light)?
- Their willingness to purchase (select) the tested Gunnar OTC glasses and the price willing to pay for.
<Study design>
Thirty-four subjects, age 18 to 42, were planned to be recruited. This sample size is based on a priori power analysis with 80% and a medium effect size at alpha equal to 0.05. Subjects will be stratified into four age groups. An about equal number (8±1) of subjects should have been recruited for each group:
- 18-23 yr old
- 24-29 yr old
- 30-35 yr old
- 36-42 yr old
Each subject was scheduled for three visits: Visit 1 for screening and consenting, visit 2 for lab test after treatment 1, and visit 3 for lab test after treatment 2. Between visits was an adaptation period for the assigned treatment.
Visit 1: A screening visit
- Day 1, when a subject first joins the study
- Obtain informed consent and screening measurements (VA, contrast sensitivity, tear film break-up time as dry eye measurement, Dry eye questionnaire (OSDI), viewing symptom survey (VSS), history of dry eye, and computer work behavior).
- At the end of the visit, half of the subjects were given a pair of Gunnar OTC glasses for adaptation for 3 - 7 days; the other half were given no treatment. All subjects were told to work in front of a computer for at least 4 hours a day, with the assigned glasses if given.
Adaptation 1:
- Starting on Day 1, for 3 to 7 days, the subject was asked to work in front of computers for at least 4 hours each day with assigned treatment 1.
Visit 2: Lab test for treatment 1
- On a day between day four and day 8 convenient to the subject, the subject came to the lab with the assigned glasses condition.
- Baseline measurements will be taken, followed by a few visual tasks under three viewing conditions. The subject was asked to fill out the VSS, given a break, before being tested on another round of tasks under a different viewing condition.
- The total testing time is about 70 minutes for each condition and about 4 hours to complete the visit.
- The lab testing procedure is described below.
- At the end of visit 2, treatment was alternated for another 3-7 days of adaptation.
Adaptation 2 with treatment 2:
- Starting on the day of Visit 2 after the test, the subject adapts to the second treatment (with Gunnar glasses or without any glasses) for another 3 to 7 days.
Visit 3: Lab test for treatment 2
- The same procedure of Visit 2 was repeated.
- Subject was asked to rate their preference of wearing the Gunnar Glasses over no-glasses when performing computer tasks.
- After this visit, the study was completed for the subject.
Details of lab testing procedures:
- The study adopted a crossover design. Each subject went through three viewing conditions (control, bright light, strong ventilating) based on a Latin Square order.
- In the control condition, the subject will perform all tasks under regular office lighting (500 lux) and the default lab ventilation condition.
- In the bright light condition, the ambient light will be increased to 1500 lux.
- In the strong ventilation condition, a ceiling fan will be positioned on top of the subject at the ceiling light location to increase the airflow. Visual performance tasks:
- Baseline measurements (10 min): Upon arrival, the subject was asked to fill out VSS and OSDI. Measurements of dry eye condition, pupil size, accommodation status, and blink rate were taken as the baseline for a visit.
- Under viewing condition 1:
- Visual tasks (60 minutes): Visual acuity, contrast sensitivity, color perception, visual search of numbers among a number matrix, low-contrast target search, text reading, and spelling check were performed by a fixed order.
- Post-task measurements of dry eye measure (Tear break uptime), pupil size, accommodation, and blink rate, as well as VSS were taken.
- Break time of 5-10 minutes.
- Repeat the above procedures for the other two viewing conditions.
- Total time for one lab visit was about 4 hours.
- Conditions
- Dry Eye, Eye Strain, Visual Acuity, Color Perception
- Being tested
- Gunnar OTC Glasses
- Keywords
- Computer Glasses, Dry eye, Eye strain, Gunnar Glasses
- Medical subject headings
- Dry Eye Syndromes, Asthenopia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Gunnar OTC GlassesDevice
Gunnar Over-the-Counter Computer Glasses have optical power of 0.5 diopters for reducing accommodation demands at a typical computer-viewing distance. The lens also have a partially transmissive yellow tinting and anti-reflective coating for filtering part of the spectral peaks in typical fluorescent or incandescent light. The frame has a wrape-around design meant to reduce air flow in the vicinity of the eyes.
| Study group | Role | What they receive |
|---|---|---|
| Experimenter: Gunnar OTC Glasses, Then Control | Experimental | On Visit 1, after the screening and baseline measurements, participants were given a pair of Gunnar OTC glasses (Intervention 1) and asked to work on the computer with the glasses for at least 4 hours for 5+/-2 days of adaptation (Habituation 1).
On Visit 2, they performed the designated computer tasks with the glasses to complete the Gunnar condition. Then they were asked to work on the computers for at least 4 hours without any glasses (Intervention 2) for another 5+/-2 days (Habituation 2).
On Visit 3, they performed the same tasks without any glasses to complete the Control condition. Then Participants responded if they prefer wearing the Gunnar OTC Glasses when working on a computer. Receives: Device: Gunnar OTC Glasses |
| Experimenter: Control, Then Gunnar OTC Glasses | Experimental | On Visit 1, after the screening and baseline measurements, participants were told to work on the computer for at least 4 hours without glasses (Intervention 1) for 5+/-2 days of adaptation (Habituation 1).
On Visit 2, they performed the designated computer tasks without glasses to complete the Control condition. Then they were given a pair of Gunnar OTC Glasses to wear (Intervention 2) while working on the computers for 4+ hours daily for another 5+/-2 days (Habituation 2).
On Visit 3, they performed the same tasks with the Gunnar glasses to complete the Gunnar condition. Then Participants responded if they prefer wearing the Gunnar OTC Glasses when working on a computer. Receives: Device: Gunnar OTC Glasses |
What is being measured
The primary outcome is the main question the study is designed to answer.
Subjective Rating of Gunnar Computer Glasses Preference
At the end of the study in Visit 3, subjects were asked to respond if they felt the Gunnar TC Glasses improved their computer viewing comfort and visual performance (choose between "Yes" and "No").
Measured: at the end of the study in Visit 3, up to day 16
Secondary outcomes (10)
Subjective Viewing Discomfort Rating
Subjective rating of viewing comfort on the Viewing Symptom Survey (15 items, 5-pt Likert scale, 0: no discomfort; 4: extremely discomfort). Factor Analysis reduced the information dimension from 15 items to 5 factors:
- Decreased cognitive function: sleepy, can't concentrate, can't think clearly, difficulty to remember
- Eyestrain: eye strain, tired eyes
- Physical discomfort: body discomfort, neckache, headache
- Decreased visual function: blurry, double vision, can't focus, moving text
- Poor balance: vertigo, dizzy A factor score is a linear transformation of the variables with weights. Its unit is arbitrary and meaningless; no min or max. However, as the values (correlation between variable and factor) in the Structure Matrix are positive, the sign of the factor is the same as the variables. Positive larger values mean more discomfort. A linear mixed model compares the relative impact of the interventions (Gunnar OTC glasses vs. Control_No glasses) on each factor.
Measured: Data were collected at the end of Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, up to Day 16).
Visual Acuity
The participant's ability to identify high-contrast objects was measured in Visits 2 and 3. Measurements were recorded in the logarithmic Measure of Angle of Resolution (logMAR) scale, in which each 'line' of the symbols on a vision chart corresponds to a unit of 0.1 and represents a 10-fold difference in acuity compared to the adjacent line of the vision. Normal (6/6 or 20/20) vision in Snellen notation equals 0.0 logMAR (logarithmic of 1.0 arc minute or 1/60 of a degree). A negative logMAR value means better than normal (20/20) vision, and a smaller logMAR represents better vision in distinguishing finer details.
Measured: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, up to Day 16)
Color Perception
Participants' best performance in discriminating the number of color saturation levels was measured during visits 2 and 3. In each trial, six circles of the same color in 1-6 shades were presented. Participants responded with the number of color shades presented. Four colors (red, green, blue, and gray) were tested and analyzed separately. Performance in gray was used as the covariate for analysis.
Measured: during Visit 2 (at leadays after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, up to Day 16)
Spelling Check Accuracy
subject's accuracy in spelling check.
Measured: Performance was measured during visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and visit 3 (at least 3 days after Visit 2, up to Day 16).
Dry Eye Measurements (1): Tear Film Break-up Time (Seconds)
Tear film break-up time (TBUT) measures the duration the tear covers the cornea surface fully until it evaporates. It reflects the stability of the tear film and is commonly used in clinics to check for evaporative dry eye syndrome. In testing for TBUT, sodium fluorescein dye is added to the eye, and the tear film is observed under the slit lamp while the patient avoids blinking until tiny dry spots develop. Larger numbers mean the tear stays on the cornea surface longer and is less severe for dry eye symptoms. Usually, TBUT values range from 3-132 seconds (average 27 seconds). TBUT less than 10 seconds suggests an abnormal tear film, 5-10 seconds considered marginal, and less than 5 seconds indicative of dry eye.
Measured: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, upto Day 16)
Contrast Sensitivity
The participant's ability to identify low-contrast objects was measured in Visits 2 and 3.
A letter contrast sensitivity test by M\&S Technology measures the subject's ability to detect objects without a clear outline and distinguish them from their background. The M\&S Letter Contrast Sensitivity Test uses standard Snellen and Sloan Letters presented at contrast levels from 100% to 0.8%, with smaller numbers indicating better performance (better contrast sensitivity).
Measured: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, up to Day 16)
Spelling Check Speed (Words Per Minute, WPM)
This measures the subject's speed (words per minute) in spelling check. Higher values mean better performance or more words being checked within one minute.
Measured: Performance was measured during visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and visit 3 (at least 3 days after Visit 2, up to Day 16).
Dry Eye Measurements 2: Tear Osmolarity Index Measured With TearLab
Tear osmolarity measures the number of milliosmoles of the solutes (e.g., salt) per liter (mOsm/L) of tear. Normal values range from 275 to 295 mOsm/L. Higher values indicate higher concentrations of electrolytes in the tear, which reflect worse dry eye conditions. A diagnosis of dry eye syndrome is made if the osmolarity of either eye is larger than 308 mOsm/L, or when the difference in measured osmolarity between eyes is >8 mOsmol/L
Measured: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, upto Day 16)
Dry Eye Measurements (3): Rating of the Corneal Integrity With Lissamine Green Staining (0-4, Lower is Better)
A score on a scale (0-4, lower number indicating a better, healthier cornea); A subjective grade on the Corneal Integrity Rating with Lissamine Green Evaluation Form, which is a clinical grading system used to assess the health and integrity of the corneal surface, particularly focusing on ocular surface damage, dryness, or irritation. It has 5 levels (0-4), with lower numbers being better. Here is the description of each level:
0: No staining; corneal surface completely intact, no signs of damage. Best possible score.
- Minimal staining; few scattered dots of stain, very mild damage or dryness.
- Moderate staining; more noticeable punctate staining but no confluent areas.
- Marked staining; numerous punctate stains, possible small areas of confluent staining.
- Severe staining; large confluent areas of stain, significant epithelial damage. Worst score.
Measured: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, upto Day 16)
Dry Eye Measurements (4): Blink Duration (Milliseconds) Measured Through Real-time Blink-contingent Visual Acuity Task
While the subject detected the orientation of a tumbling E, we measured the average interval between two blinks. Larger numbers mean a longer duration of a blink sustained.
Measured: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, upto Day 16)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Oct 2016 (estimated)
- Study startJun 2013
- Primary completionSep 2013
- Study completionSep 2013
Why it stopped: The sponsor failed to provide financial support as promised.
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Other trials for Dry EyeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 35 participants (actual)
Sponsor and investigators
- Lead sponsor
- Pacific University
- Sponsor type
- University, hospital or other
- Collaborators
- Gunnar Optiks
- Responsible party
- Principal investigator, Yu-Chi Tai, Pacific University
- Investigators
- Yu-Chi Tai, PhD, Principal investigator, Pacific University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02925884
- Sponsor's protocol ID
- PUIRB075-13
- Other IDs
- Gunnar2013
- Status last verified
- Jun 2025
- First submitted
- 17 Jun 2013
- Last updated
- 16 Jul 2025
- Results posted
- Yes, on ClinicalTrials.gov
- Data monitoring committee
- No
- Individual data sharing
- No: There is not a plan to make IPD available.
Study at a glance
From the registry record, last updated by the sponsor on 16 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Computer Eyewear on Viewing Comfort and Performance in Office Work
- ClinicalTrials.gov ID
- NCT02925884
- Acronym / sponsor ID
- PUIRB075-13
- Conditions
- Dry Eye, Eye Strain, Visual Acuity, Color Perception
- Keywords
- Computer Glasses, Dry eye, Eye strain, Gunnar Glasses
- Study type
- Interventional
- Recruitment status
- TerminatedReason stopped: The sponsor failed to provide financial support as promised.
- Enrolment
- 35 participants (actual)
- Lead sponsor
- Pacific UniversityUniversity, hospital or other
- Collaborators
- Gunnar Optiks
- Study start
- Jun 2013
- Primary completion
- Sep 2013 (actual)
- Study completion
- Sep 2013 (actual)
- First posted
- 6 Oct 2016 (estimated)
- Results
- Posted 16 Jul 2025
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The proposed study aims to test if Gunnar computer glasses provide any advantages, in comparison to no glasses, on the following aspects in computer-related office work:
- Any enhancement on the visual performance of the basic visual function, including visual acuity, contrast sensitivity, color discrimination, etc.
- Any enhancement on the visual performance of typical office work, including reading, word-spelling check, number searching, or target identification.
- Any benefit in objective viewing comfort measured with viewing distance, blink frequency, post-viewing pupil size.
- Any benefit in subjective viewing comfort reflected on the questionnaire of viewing symptom survey.
- Any benefit in viewing comfort and visual performance with increased environmental ventilation or under the strong glare.
- Any benefit in life quality from daily wearing (e.g., better comfort or sleep quality).
Detailed description
<Introduction>
When performing near work, one must focus at (accommodate) and point toward (converge) at a closer distance and constantly re-focus the eyes to see small text and images with clarity. Sustaining such efforts can lead to eye fatigue and eye strain, among a host of vision problems. Most visual tasks on a screen also demand heightened visual concentration, and this decreases blink rate. Working in a heated or air-conditioned office environment leads to over-evaporation of the tear film, and lipid deficiency, irritation, and dryness to the corneal surface are expected. Disruptive glare from excessive screen reflection and ambient lighting also deteriorates the image quality and heaps on viewing discomfort. Extensive screen viewing also exacerbates discomfort in people with existing vision problems like eye muscle imbalance, astigmatism, farsightedness, and presbyopia. Since technology is almost unavoidable to modern life, preventions should be taken to lessen the total toll on the eyes and visual system. Gunnar computer glasses address the above issues by providing mild yellow tint anti-reflection coating to shield the harmful blue light and lessen strong glare. The glasses also have a small amount of magnification (+0.5 D) to enhance acuity. The curved frame is designed to retain moisture and reduce dry eye symptoms. All these special characters are devised to enhance visual performance and minimize eye fatigue and visual discomfort in digital viewing. The current study aimed to validate the benefits mentioned above.
Gunnar over-the-counter (OTC) computer glasses adopt yellow lenses to cut off the active short wavelength and lessen the bright glare, which often induces the detrimental effect caused by excessive illumination or intense scattered reflection. While the benefit of glare reduction is well received, the benefit on visual performance has been inconclusive. Some studies reported a significant enhancement in contrast sensitivity, but some failed to see any improvement in visual acuity and contrast sensitivity, even with color distortion. Without argument, tinted lenses reduce the transmittance of the visible spectrum and change the visible color to a certain degree. However, there has been a report that reducing the retinal illumination level does not necessarily lead to reduced brightness; instead, the visual system automatically adjusts for the illumination discounting, possibly with the help of increased pupil size. In addition, with the decrement of blue lights arriving at the eyes, both scattered reflection and chromatic aberration are reduced. Together, it is reasonable to believe that the visual acuity, contrast sensitivity, and chromatic discrimination will not suffer and may, instead, benefit from the filter of yellow lenses. These basic visual functions may, in turn, lead to enhancement in general visual performance such as routine office work. These will be tested in the proposed study.
The current study tested if Gunnar's OTC computer glasses provide any advantages, in comparison to no glasses, on the following aspects in computer-related office work:
- Any enhancement on the visual performance of the basic visual function, including visual acuity, contrast sensitivity, color discrimination, etc.
- Any enhancement on the visual performance of typical office work, including reading, word-spelling check, number searching, or target identification.
- Any benefit in preventing dry eye by measuring the humidity outside and inside the frame (only in the visit with Gunnar glasses) and the tear film break-up time after viewing for a prolonged period.
- Any benefit in objective viewing comfort measured with viewing distance, blink frequency, post-viewing pupil size.
- Any benefit in subjective viewing comfort reflected on the questionnaire of viewing symptom survey.
- Any benefit in viewing comfort and visual performance with increased environmental ventilation.
- Any benefit in viewing comfort and visual performance with increased environment under the intense glare.
- Any benefit in life quality from daily wearing (e.g., viewing comfort, sleep quality, or quantity due to the amount of stimulation from blue light)?
- Their willingness to purchase (select) the tested Gunnar OTC glasses and the price willing to pay for.
<Study design>
Thirty-four subjects, age 18 to 42, were planned to be recruited. This sample size is based on a priori power analysis with 80% and a medium effect size at alpha equal to 0.05. Subjects will be stratified into four age groups. An about equal number (8±1) of subjects should have been recruited for each group:
- 18-23 yr old
- 24-29 yr old
- 30-35 yr old
- 36-42 yr old
Each subject was scheduled for three visits: Visit 1 for screening and consenting, visit 2 for lab test after treatment 1, and visit 3 for lab test after treatment 2. Between visits was an adaptation period for the assigned treatment.
Visit 1: A screening visit
- Day 1, when a subject first joins the study
- Obtain informed consent and screening measurements (VA, contrast sensitivity, tear film break-up time as dry eye measurement, Dry eye questionnaire (OSDI), viewing symptom survey (VSS), history of dry eye, and computer work behavior).
- At the end of the visit, half of the subjects were given a pair of Gunnar OTC glasses for adaptation for 3 - 7 days; the other half were given no treatment. All subjects were told to work in front of a computer for at least 4 hours a day, with the assigned glasses if given.
Adaptation 1:
- Starting on Day 1, for 3 to 7 days, the subject was asked to work in front of computers for at least 4 hours each day with assigned treatment 1.
Visit 2: Lab test for treatment 1
- On a day between day four and day 8 convenient to the subject, the subject came to the lab with the assigned glasses condition.
- Baseline measurements will be taken, followed by a few visual tasks under three viewing conditions. The subject was asked to fill out the VSS, given a break, before being tested on another round of tasks under a different viewing condition.
- The total testing time is about 70 minutes for each condition and about 4 hours to complete the visit.
- The lab testing procedure is described below.
- At the end of visit 2, treatment was alternated for another 3-7 days of adaptation.
Adaptation 2 with treatment 2:
- Starting on the day of Visit 2 after the test, the subject adapts to the second treatment (with Gunnar glasses or without any glasses) for another 3 to 7 days.
Visit 3: Lab test for treatment 2
- The same procedure of Visit 2 was repeated.
- Subject was asked to rate their preference of wearing the Gunnar Glasses over no-glasses when performing computer tasks.
- After this visit, the study was completed for the subject.
Details of lab testing procedures:
- The study adopted a crossover design. Each subject went through three viewing conditions (control, bright light, strong ventilating) based on a Latin Square order.
- In the control condition, the subject will perform all tasks under regular office lighting (500 lux) and the default lab ventilation condition.
- In the bright light condition, the ambient light will be increased to 1500 lux.
- In the strong ventilation condition, a ceiling fan will be positioned on top of the subject at the ceiling light location to increase the airflow. Visual performance tasks:
- Baseline measurements (10 min): Upon arrival, the subject was asked to fill out VSS and OSDI. Measurements of dry eye condition, pupil size, accommodation status, and blink rate were taken as the baseline for a visit.
- Under viewing condition 1:
- Visual tasks (60 minutes): Visual acuity, contrast sensitivity, color perception, visual search of numbers among a number matrix, low-contrast target search, text reading, and spelling check were performed by a fixed order.
- Post-task measurements of dry eye measure (Tear break uptime), pupil size, accommodation, and blink rate, as well as VSS were taken.
- Break time of 5-10 minutes.
- Repeat the above procedures for the other two viewing conditions.
- Total time for one lab visit was about 4 hours.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Experimenter: Gunnar OTC Glasses, Then Control | Experimental | Device: Gunnar OTC GlassesOn Visit 1, after the screening and baseline measurements, participants were given a pair of Gunnar OTC glasses (Intervention 1) and asked to work on the computer with the glasses for at least 4 hours for 5+/-2 days of adaptation (Habituation 1). On Visit 2, they performed the designated computer tasks with the glasses to complete the Gunnar condition. Then they were asked to work on the computers for at least 4 hours without any glasses (Intervention 2) for another 5+/-2 days (Habituation 2). On Visit 3, they performed the same tasks without any glasses to complete the Control condition. Then Participants responded if they prefer wearing the Gunnar OTC Glasses when working on a computer. |
| Experimenter: Control, Then Gunnar OTC Glasses | Experimental | Device: Gunnar OTC GlassesOn Visit 1, after the screening and baseline measurements, participants were told to work on the computer for at least 4 hours without glasses (Intervention 1) for 5+/-2 days of adaptation (Habituation 1). On Visit 2, they performed the designated computer tasks without glasses to complete the Control condition. Then they were given a pair of Gunnar OTC Glasses to wear (Intervention 2) while working on the computers for 4+ hours daily for another 5+/-2 days (Habituation 2). On Visit 3, they performed the same tasks with the Gunnar glasses to complete the Gunnar condition. Then Participants responded if they prefer wearing the Gunnar OTC Glasses when working on a computer. |
Who may qualify
- Ages
- 18 to 42 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Subjects must be between 18 to 42 years old.
- Subjects must have a normal color vision (be able to identify the numbers in the color blind test.
- Subjects' near and far visual acuity with the better eye needs to be 20/25 or better (measured with a vision chart). Subjects can wear contact lenses (but not glasses) if usually wear them while working on computers.
- Subjects must routinely work on a computer or digital display for an average of 4 hours or more each day.
- Subjects can communicate in English fluently and are used to read English documents on a computer.
Key exclusion criteria (5 listed)
- The difference in the prescription for both eyes is equal to or larger than 2 Diopters.
- Subjects have a cataract or have had cataract surgery.
- Subjects are sensitive to lights (photosensitivity).
- Subjects have prior incidents or are known to have claustrophobia.
- Subjects have been diagnosed with oculomotor diseases or central nervous system diseases, or with developmental, neurological, or psychiatric disorders (e.g., attention deficit hyperactivity disorder, autism, mental retardation).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Gunnar OTC GlassesGunnar Over-the-Counter Computer Glasses have optical power of 0.5 diopters for reducing accommodation demands at a typical computer-viewing distance. The lens also have a partially transmissive yellow tinting and anti-reflective coating for filtering part of the spectral peaks in typical fluorescent or incandescent light. The frame has a wrape-around design meant to reduce air flow in the vicinity of the eyes. | Device | Experimenter: Control, Then Gunnar OTC Glasses, Experimenter: Gunnar OTC Glasses, Then Control |
Primary outcome
Subjective Rating of Gunnar Computer Glasses Preference
Time frame: at the end of the study in Visit 3, up to day 16
At the end of the study in Visit 3, subjects were asked to respond if they felt the Gunnar TC Glasses improved their computer viewing comfort and visual performance (choose between "Yes" and "No").
10 secondary outcomes
Subjective Viewing Discomfort Rating
Time frame: Data were collected at the end of Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, up to Day 16).
Visual Acuity
Time frame: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, up to Day 16)
Color Perception
Time frame: during Visit 2 (at leadays after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, up to Day 16)
Spelling Check Accuracy
Time frame: Performance was measured during visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and visit 3 (at least 3 days after Visit 2, up to Day 16).
Dry Eye Measurements (1): Tear Film Break-up Time (Seconds)
Time frame: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, upto Day 16)
Contrast Sensitivity
Time frame: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, up to Day 16)
Spelling Check Speed (Words Per Minute, WPM)
Time frame: Performance was measured during visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and visit 3 (at least 3 days after Visit 2, up to Day 16).
Dry Eye Measurements 2: Tear Osmolarity Index Measured With TearLab
Time frame: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, upto Day 16)
Dry Eye Measurements (3): Rating of the Corneal Integrity With Lissamine Green Staining (0-4, Lower is Better)
Time frame: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, upto Day 16)
Dry Eye Measurements (4): Blink Duration (Milliseconds) Measured Through Real-time Blink-contingent Visual Acuity Task
Time frame: during Visit 2 (at least 3 days after Visit 1, between Day 4 and Day 8) and Visit 3 (at least 3 days after Visit 2, upto Day 16)
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jul 2025.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Summary of the current findingsLink provided by the sponsor.
- Individual participant dataSharing planned: No. There is not a plan to make IPD available.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Yu-Chi Tai, PhD principal investigator
Pacific University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Gunnar OTC Glasses in people with Dry Eye and Eye Strain, run by Pacific University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 16 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 16 Jul 2025). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Subjective Rating of Gunnar Computer Glasses Preference (time frame: at the end of the study in Visit 3, up to day 16). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jul 2025.