Adolescent BehaviorAVIDNCT03059433
Randomized Trial of a Social Networks Intervention
An observational study of Adolescent Behavior, run by University of California, Los Angeles at 1 site in United States.
Trial summary
Advancement via Individual Determination (AVID) is a college preparatory program that provides a unique opportunity to determine whether schools can reduce substance use by re-grouping at-risk students with high-performing students, while providing additional academic and emotional support. Read more about this study
- Who is it for?
- Ages 13 to 18 yearsHealthy volunteers can take part
- Conditions the study is for
- Adolescent Behavior
- What is being tested?
- AVID Intervention
- How many people
- 446 participants
- Where
- 1 siteUnited States
- Study dates
- 21 Apr 2017to 6 Jul 2022
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 to 18 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Study population: Participants must be eighth grade students who are entering a Los Angeles Unified School District high school that is having a lottery for admission into their AVID program.
Who may be able to join
- applied to and was deemed eligible for AVID by the AVID coordinator
- Student participated in the AVID lottery
- Parent consents to participate in study
- Student assents to participate in study
- OR
- Middle school Grade Point Average (GPA) >3.5
Show all 9Show fewer
- Planning to attend study high school
- Parent consents to participate in study
- Student assents to participate in study
Who cannot join
- Student did not apply to AVID
- Student was deemed ineligible for AVID by the AVID coordinator/local AVID admissions process
- Student did not participate in the AVID lottery
- Parent does not consent for study participation
- Student does not assent for study participation
- OR
Show all 10Show fewer
- Middle school Grade Point Average (GPA)<3.5
- Not planning to attend study high school
- Parent does not consent for study participation
- Student does not assent for study participation
Trial locations and contacts
1 site in 1 country.
United States1 site
University of California, Los Angeles (UCLA)
Los Angeles, California, 90095
About this study
Official title: Leveraging School Environments to Shape Social Networks and Reduce Adolescent Substance Use-A Pilot Randomized Trial of a Social Networks Intervention
Advancement via Individual Determination (AVID) is a college preparatory program that provides a unique opportunity to determine whether schools can reduce substance use by re-grouping at-risk students with high-performing students, while providing additional academic and emotional support. Operating in 4,837 K-12th grade schools worldwide and across 45 US states, this widely-disseminated program targets students from groups traditionally underrepresented in higher education who are currently performing in the academic middle (i.e., a 2.0-3.5 grade point average). AVID removes these students from typical classrooms and exposes them to a peer network in which academic performance and positive social norms are valued. In addition, by strengthening the student/teacher relationship, AVID expands students' networks of supportive adults. For low-income minority students in the academic middle, relatively small investments in prevention might significantly impact their academic and health trajectories. AVID capitalizes on a moment when social networks are in flux-the transition to high school-to shift these students' trajectories.
This study is a longitudinal, randomized pilot evaluation of AVID among low-income minority adolescents entering high school, comparing academic performance and drug use, as well as other risky behaviors, over 3 years. Although social networks are hypothesized to have a strong influence on behavior, few studies have tried to re-wire networks to change behaviors. This study will provide a clearer understanding of whether schools can intentionally shape networks and whether these changes can reduce substance use. This study will also explore important mechanistic questions about whether and how AVID changes peer networks and relationships with teachers, whether those changes lead to improvements in academic and behavioral outcomes and, if so, what the relative importance of peer versus adult network changes are.
Read the detailed description
Substance use is an increasing problem among adolescents. Despite decades of prevention work, most recent data suggest that, by the end of high school, a quarter of teens regularly use marijuana and nearly half regularly use alcohol. While adolescent marijuana use has increased across the country in the last decade, rates in California are higher than the national average. This may be partially attributable to increased social acceptance and access through legalized dispensaries. As the movement to legalize marijuana gains traction, similar changes are likely to occur throughout the country. The high prevalence of alcohol and marijuana use is particularly disturbing in light of evidence that even intermittent adolescent exposure may have long-term impacts on brain development, in addition to associations with other risky health behaviors and future substance abuse disorders. African American and Latino youth are especially at risk, making adolescent substance use prevention a potentially important strategy to address health disparities.
Few effective and sustainable substance use interventions exist for high school students. Preventing substance use becomes more challenging as adolescents age, with fewer prevention programs demonstrating success for high school youth than for middle school youth. The challenge is to identify modifiable predictors of substance use for high-school youth and harness them for prevention. Furthermore, most interventions are difficult to disseminate and sustain due to limits on financial and human capital. AVID is already widely implemented in public schools. Thus, if AVID is effective in reducing substance use while also improving academic outcomes, the program would serve as a promising model for future interventions.
Social networks are likely to powerfully influence adolescent substance use. There is strong and consistent evidence that adolescent substance use is closely tied to the behaviors and attitudes of individuals in their social network. Social network structure and composition are shaped by cultural and environmental factors. In school environments, these factors include policies like tracking of students based on prior achievement. Social networks then determine sources of support, transmission of social norms, and access and opportunity to engage in substance use. Although peers are powerful points of influence during adolescence, relationships with supportive adults can continue to protect against substance use.
Despite great interest in social networks as potential determinants of risky behaviors, causal pathways linking social networks with adolescent health have yet to be fully categorized. Studies suggest that changes in social networks can impact substance use, but little is known about how to harness this relationship effectively. Answering this question may have applications across many social environments and health domains. Interventions that re-wire social networks might offer a relatively low-cost, self-sustaining, and effective means to prevent some of the most challenging behaviors that lead to poor health outcomes. School environments present a critical opportunity to impact adolescent health. Through near-daily exposure, school environments have the potential to shape adolescents' relationships, social norms, sense of identity, and educational attainment. These factors are likely to be mutually reinforcing and are strongly associated with substance use.
AVID, a widely used educational intervention, offers an important opportunity to test whether schools can re-wire social networks to improve adolescent health. AVID removes middle-performing students from a typical school environment, where social pressure often reinforces low academic achievement and problem behaviors, and places them alongside high-performing students in a college-preparatory environment where positive social norms are valued. AVID capitalizes on a natural transition point, when social networks are in flux, by targeting students at the beginning of 9th grade. Perhaps not coincidentally, 9th grade is also an enormously vulnerable period-36% of high school drop-outs do so in 9th grade, and only 15% of 9th graders who are held back will ever graduate. Finally, the program emphasizes the student/teacher relationship, training teachers to serve as mentors and student advocates, providing both academic and emotional support to cultivate a family-like atmosphere. Through the proposed randomized controlled pilot evaluation of AVID, investigators can measure whether the program successfully changes social networks, and test whether changes in social networks motivate changes in substance use. Understanding whether AVID's return on investment extends to health outcomes is vitally important given the limited resources available to support multiple competing K-12 education initiatives.
The Los Angeles Unified School District (LAUSD) implemented AVID to provide academic and social support to students from groups traditionally under-represented in higher education (e.g., students of color, first generation to attend college). AVID is an international non-profit institution originally established in 1980 by a San Diego high school teacher. AVID's goal is to prepare vulnerable students functioning in the academic middle for success at a 4-year university. Students in each school must actively apply to the program to demonstrate both eligibility and interest. AVID's eligibility criteria include having a grade point average of 2.0-3.5 and returning a contract signed by the student and a parent indicating that the student chooses to participate in the program, has a desire to go to college, and agrees to enroll in rigorous academic courses. Identification of eligible candidates for AVID occurs during the second half of 8th grade, prior to high school entry, and is led by the AVID coordinator. At nearly every AVID high school, the number of students who qualify for AVID far outweighs the program's capacity-there are, on average, 40 AVID slots per school, which results in AVID serving only 12% of the student body. In LAUSD, the demographics of AVID students match those of the district-low-income, and African American or Latino. For example, in 2014, 86% of LAUSD's AVID students were Latino, 6% were African American, and 89% qualified for free or reduced lunch.
LAUSD's AVID program has agreed to allow investigators to recruit study participants from the pool of students who meet the AVID eligibility requirements as well as a group of high performing (middle school grade point average (GPA) >3.5) students who are not AVID eligible. Near the end of 8th grade, LAUSD will randomize all AVID eligible applicants through a lottery into either AVID or a waitlist group. Prior to the random assignments being revealed, investigators will ask all students randomized into AVID and an equal number of students randomized into the waitlist group to return a signed parental consent form for study participation and to complete a survey. Students will be recruited and surveyed prior to revealing their assignment to avoid any response biases caused by happiness or disappointment at the lottery result. Decisions to participate in the study will have no impact on the lottery itself. Investigators will survey all study participants at the end of 8th grade, 9th grade, 10th grade, and 11th grade.
- Conditions
- Adolescent Behavior
- Being tested
- AVID Intervention
- Keywords
- Substance use, adolescent, health, social network
- Medical subject headings
- Adolescent Behavior, Substance-Related Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
AVID InterventionOther
Also called AVID
Advancement via Individual Determination (AVID) is a college preparatory program that participating high schools have available to students.
| Study group | Role | What they receive |
|---|---|---|
| AVID Intervention | 175 students will be randomized via lottery by the participating high school to be part of the AVID program. These students will receive 4 surveys (8th, 9th, 10th, and 11th grade). Receives: Other: AVID Intervention | |
| Non AVID | 175 students will be randomized via lottery by the participating high school to be part of our control group. This group of students will be similar to the AVID group, except they will not be in the AVID program. They will also complete 4 surveys (8th, 9th, 10th, and 11th grade). | |
| High Performing | 175 students who are identified as high performing (middle school grade point average >3.5) by the participating high school. They will also complete 4 surveys (8th, 9th, 10th, and 11th grade). |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in health of social network
Investigators will evaluate whether students randomized to AVID report healthier social networks (lower proportion of peers engaging in risky behaviors and a higher number of supportive adults) than control students.
Measured: change in health of social network between baseline and 3 year follow up
Secondary outcomes (3)
Frequency of risky health behaviors
Investigators will determine whether AVID students report decreased frequency of risky health behaviors, such as substance use, violence, and delinquency, compared to control students and whether associations between AVID and risky health behaviors are modified by gender.
Measured: change in frequency of risky health behaviors between baseline and 3 year follow up
Change in peer or adult social network
Investigators will examine whether peer or adult social network changes predict changes in risky health behaviors and, if exposure to AVID is associated with health behaviors, whether these associations are mediated by changes in peer or adult networks.
Measured: change in risky behavior between baseline and 3 year follow up
Assumptions of AVID students' level of their own risky health behaviors
Investigators will test whether AVID students assume similar levels of risky health behaviors as reported by high-performing, non-AVID peers, and whether, for high-performing non-AVID peers, a greater proportion of AVID peers in their social network is associated with increased frequency of risky health behaviors.
Measured: change in student assumption of risky behavior between baseline and 3 year follow up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Feb 2017
- Study start21 Apr 2017
- Primary completion2 Jul 2021
- Study completion6 Jul 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Adolescent BehaviorStudies of the same condition, open and under way.
- More trials run by University of California, Los AngelesThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 446 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of California, Los Angeles
- Sponsor type
- University, hospital or other
- Collaborators
- Robert Wood Johnson Foundation
- Responsible party
- Principal investigator, Rebecca Dudovitz, MD, MSHS, University of California, Los Angeles
- Investigators
- Rebecca Dudovitz, MD, MS, Principal investigator, University of California, Los Angeles
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03059433
- Sponsor's protocol ID
- IRB#15-001190
- Acronym
- AVID
- Status last verified
- Sep 2022
- First submitted
- 13 Feb 2017
- Last updated
- 3 Oct 2022
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Participants will be assigned a study ID number to link their name, address, and phone number to their survey responses. This ID will be used for all data collection. The computer file linking the personal identifiers and the study ID number will be kept separate from the survey data. Personally identifying information pertaining to individual participants will not be shared or made available to other researchers. Any data request will be made to the Principal Investigator and any data shared will be encrypted and will not include any personal identifying information.
Study at a glance
From the registry record, last updated by the sponsor on 3 Oct 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Leveraging School Environments to Shape Social Networks and Reduce Adolescent Substance Use-A Pilot Randomized Trial of a Social Networks Intervention
- ClinicalTrials.gov ID
- NCT03059433
- Acronym / sponsor ID
- AVID / IRB#15-001190
- Conditions
- Adolescent Behavior
- Keywords
- Substance use, adolescent, health, social network
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 446 participants (actual)
- Lead sponsor
- University of California, Los AngelesUniversity, hospital or other
- Collaborators
- Robert Wood Johnson Foundation
- Study start
- 21 Apr 2017 (actual)
- Primary completion
- 2 Jul 2021 (actual)
- Study completion
- 6 Jul 2022 (actual)
- First posted
- 23 Feb 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Advancement via Individual Determination (AVID) is a college preparatory program that provides a unique opportunity to determine whether schools can reduce substance use by re-grouping at-risk students with high-performing students, while providing additional academic and emotional support. Operating in 4,837 K-12th grade schools worldwide and across 45 US states, this widely-disseminated program targets students from groups traditionally underrepresented in higher education who are currently performing in the academic middle (i.e., a 2.0-3.5 grade point average). AVID removes these students from typical classrooms and exposes them to a peer network in which academic performance and positive social norms are valued. In addition, by strengthening the student/teacher relationship, AVID expands students' networks of supportive adults. For low-income minority students in the academic middle, relatively small investments in prevention might significantly impact their academic and health trajectories. AVID capitalizes on a moment when social networks are in flux-the transition to high school-to shift these students' trajectories.
This study is a longitudinal, randomized pilot evaluation of AVID among low-income minority adolescents entering high school, comparing academic performance and drug use, as well as other risky behaviors, over 3 years. Although social networks are hypothesized to have a strong influence on behavior, few studies have tried to re-wire networks to change behaviors. This study will provide a clearer understanding of whether schools can intentionally shape networks and whether these changes can reduce substance use. This study will also explore important mechanistic questions about whether and how AVID changes peer networks and relationships with teachers, whether those changes lead to improvements in academic and behavioral outcomes and, if so, what the relative importance of peer versus adult network changes are.
Detailed description
Substance use is an increasing problem among adolescents. Despite decades of prevention work, most recent data suggest that, by the end of high school, a quarter of teens regularly use marijuana and nearly half regularly use alcohol. While adolescent marijuana use has increased across the country in the last decade, rates in California are higher than the national average. This may be partially attributable to increased social acceptance and access through legalized dispensaries. As the movement to legalize marijuana gains traction, similar changes are likely to occur throughout the country. The high prevalence of alcohol and marijuana use is particularly disturbing in light of evidence that even intermittent adolescent exposure may have long-term impacts on brain development, in addition to associations with other risky health behaviors and future substance abuse disorders. African American and Latino youth are especially at risk, making adolescent substance use prevention a potentially important strategy to address health disparities.
Few effective and sustainable substance use interventions exist for high school students. Preventing substance use becomes more challenging as adolescents age, with fewer prevention programs demonstrating success for high school youth than for middle school youth. The challenge is to identify modifiable predictors of substance use for high-school youth and harness them for prevention. Furthermore, most interventions are difficult to disseminate and sustain due to limits on financial and human capital. AVID is already widely implemented in public schools. Thus, if AVID is effective in reducing substance use while also improving academic outcomes, the program would serve as a promising model for future interventions.
Social networks are likely to powerfully influence adolescent substance use. There is strong and consistent evidence that adolescent substance use is closely tied to the behaviors and attitudes of individuals in their social network. Social network structure and composition are shaped by cultural and environmental factors. In school environments, these factors include policies like tracking of students based on prior achievement. Social networks then determine sources of support, transmission of social norms, and access and opportunity to engage in substance use. Although peers are powerful points of influence during adolescence, relationships with supportive adults can continue to protect against substance use.
Despite great interest in social networks as potential determinants of risky behaviors, causal pathways linking social networks with adolescent health have yet to be fully categorized. Studies suggest that changes in social networks can impact substance use, but little is known about how to harness this relationship effectively. Answering this question may have applications across many social environments and health domains. Interventions that re-wire social networks might offer a relatively low-cost, self-sustaining, and effective means to prevent some of the most challenging behaviors that lead to poor health outcomes. School environments present a critical opportunity to impact adolescent health. Through near-daily exposure, school environments have the potential to shape adolescents' relationships, social norms, sense of identity, and educational attainment. These factors are likely to be mutually reinforcing and are strongly associated with substance use.
AVID, a widely used educational intervention, offers an important opportunity to test whether schools can re-wire social networks to improve adolescent health. AVID removes middle-performing students from a typical school environment, where social pressure often reinforces low academic achievement and problem behaviors, and places them alongside high-performing students in a college-preparatory environment where positive social norms are valued. AVID capitalizes on a natural transition point, when social networks are in flux, by targeting students at the beginning of 9th grade. Perhaps not coincidentally, 9th grade is also an enormously vulnerable period-36% of high school drop-outs do so in 9th grade, and only 15% of 9th graders who are held back will ever graduate. Finally, the program emphasizes the student/teacher relationship, training teachers to serve as mentors and student advocates, providing both academic and emotional support to cultivate a family-like atmosphere. Through the proposed randomized controlled pilot evaluation of AVID, investigators can measure whether the program successfully changes social networks, and test whether changes in social networks motivate changes in substance use. Understanding whether AVID's return on investment extends to health outcomes is vitally important given the limited resources available to support multiple competing K-12 education initiatives.
The Los Angeles Unified School District (LAUSD) implemented AVID to provide academic and social support to students from groups traditionally under-represented in higher education (e.g., students of color, first generation to attend college). AVID is an international non-profit institution originally established in 1980 by a San Diego high school teacher. AVID's goal is to prepare vulnerable students functioning in the academic middle for success at a 4-year university. Students in each school must actively apply to the program to demonstrate both eligibility and interest. AVID's eligibility criteria include having a grade point average of 2.0-3.5 and returning a contract signed by the student and a parent indicating that the student chooses to participate in the program, has a desire to go to college, and agrees to enroll in rigorous academic courses. Identification of eligible candidates for AVID occurs during the second half of 8th grade, prior to high school entry, and is led by the AVID coordinator. At nearly every AVID high school, the number of students who qualify for AVID far outweighs the program's capacity-there are, on average, 40 AVID slots per school, which results in AVID serving only 12% of the student body. In LAUSD, the demographics of AVID students match those of the district-low-income, and African American or Latino. For example, in 2014, 86% of LAUSD's AVID students were Latino, 6% were African American, and 89% qualified for free or reduced lunch.
LAUSD's AVID program has agreed to allow investigators to recruit study participants from the pool of students who meet the AVID eligibility requirements as well as a group of high performing (middle school grade point average (GPA) >3.5) students who are not AVID eligible. Near the end of 8th grade, LAUSD will randomize all AVID eligible applicants through a lottery into either AVID or a waitlist group. Prior to the random assignments being revealed, investigators will ask all students randomized into AVID and an equal number of students randomized into the waitlist group to return a signed parental consent form for study participation and to complete a survey. Students will be recruited and surveyed prior to revealing their assignment to avoid any response biases caused by happiness or disappointment at the lottery result. Decisions to participate in the study will have no impact on the lottery itself. Investigators will survey all study participants at the end of 8th grade, 9th grade, 10th grade, and 11th grade.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| AVID Intervention | – | Other: AVID Intervention175 students will be randomized via lottery by the participating high school to be part of the AVID program. These students will receive 4 surveys (8th, 9th, 10th, and 11th grade). |
| Non AVID | – | –175 students will be randomized via lottery by the participating high school to be part of our control group. This group of students will be similar to the AVID group, except they will not be in the AVID program. They will also complete 4 surveys (8th, 9th, 10th, and 11th grade). |
| High Performing | – | –175 students who are identified as high performing (middle school grade point average >3.5) by the participating high school. They will also complete 4 surveys (8th, 9th, 10th, and 11th grade). |
Who may qualify
- Ages
- 13 to 18 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
- Study population
- Participants must be eighth grade students who are entering a Los Angeles Unified School District high school that is having a lottery for admission into their AVID program.
Key inclusion criteria (9 listed)
- applied to and was deemed eligible for AVID by the AVID coordinator
- Student participated in the AVID lottery
- Parent consents to participate in study
- Student assents to participate in study
- OR
Key exclusion criteria (10 listed)
- Student did not apply to AVID
- Student was deemed ineligible for AVID by the AVID coordinator/local AVID admissions process
- Student did not participate in the AVID lottery
- Parent does not consent for study participation
- Student does not assent for study participation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| AVID InterventionAlso: AVIDAdvancement via Individual Determination (AVID) is a college preparatory program that participating high schools have available to students. | Other | AVID Intervention |
Primary outcome
Change in health of social network
Time frame: change in health of social network between baseline and 3 year follow up
Investigators will evaluate whether students randomized to AVID report healthier social networks (lower proportion of peers engaging in risky behaviors and a higher number of supportive adults) than control students.
3 secondary outcomes
Frequency of risky health behaviors
Time frame: change in frequency of risky health behaviors between baseline and 3 year follow up
Change in peer or adult social network
Time frame: change in risky behavior between baseline and 3 year follow up
Assumptions of AVID students' level of their own risky health behaviors
Time frame: change in student assumption of risky behavior between baseline and 3 year follow up
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Oct 2022.
- Individual participant dataSharing planned: No. Participants will be assigned a study ID number to link their name, address, and phone number to their survey responses. This ID will be used for all data collection. The computer file linking the personal identifiers and the study ID number will be kept separate from the survey data. Personally identifying information pertaining to individual participants will not be shared or made available to other researchers. Any data request will be made to the Principal Investigator and any data shared will be encrypted and will not include any personal identifying information.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Rebecca Dudovitz, MD, MS principal investigator
University of California, Los Angeles
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Adolescent Behavior, run by University of California, Los Angeles at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Oct 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in health of social network (time frame: change in health of social network between baseline and 3 year follow up). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Oct 2022.