Poisoning by Psychoactive SubstancesMusitox®NCT03203213
Musitox® Project: Consumption of Psychoactive Substances at Music Festivals in Aquitaine
A study testing Sampling of a few drops of blood, lock of hair and urine in people with Poisoning by Psychoactive Substances, run by University Hospital, Bordeaux at 1 site in France.
Trial summary
Poisoning by psychoactive substances is increasingly common in Europe and can be responsible for deaths. These substances, also called "festive drugs", circulate among other places in festive gatherings (night clubs, concerts, free music, feria, etc.). Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Poisoning by Psychoactive Substances
- What is being tested?
- Sampling of a few drops of blood, lock of hair and urine
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 25 participants
- Where
- 1 siteFrance
- Study dates
- 30 Jun 2017to 3 Jul 2017
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Any patient admitted to the Emergency Medical Post with neurological and / or behavioral disorders:
- agitated at the time of admission to the PMA or during surveillance at the LDC
- and who will say (or for whom his entourage will say that he has) consumed psychoactive substances
- or who will be unable to say that they have taken a psychoactive substance and for which no other etiology is evident
- and / or for which the seriousness of the case necessitates admission to the emergency or intensive care, whether or not the physician is aware of a psychoactive substance (and in the absence of an obvious etiology)
- and / or if the PMA physician considers that analytical research is needed for further care
- Oral Express Consent
- any patient who is in possession of an identity document proving his / her majority (over 18 years).
Who cannot join
- Refusal of the patient to take a sample, or to participate in the study
- Minors (under 18 years of age)
- Pregnant women
- Breastfeeding women
- Patient who can not prove his / her age by the production of an identity document.
Trial locations and contacts
1 site in 1 country.
About this study
Poisoning by psychoactive substances is increasingly common in Europe and can be responsible for deaths. These substances, also called "festive drugs", circulate among other places in festive gatherings (night clubs, concerts, free music, feria, etc.). The main objective of this study is to determine the molecules that circulate in festive events in Aquitaine, in order to implement prevention actions by looking at whether the circulating substances vary with the style of event.
Read the detailed description
Poisoning by psychoactive substances is increasingly common in Europe and can be responsible for deaths. These substances, also called "festive drugs", circulate among other places in festive gatherings (night clubs, concerts, free music, feria, etc.).
There is also a significant increase in the number of new psychoactive substances (NSPs) whose toxicity is unknown: by 2014, 101 new substances were detected for the first time in Europe. These molecules, because of this regular and rapid emergence, are not included in the narcotics list, in the great majority of cases.
Poison control centers, as well as addictovigilance centers, are regularly called upon for serious poisoning resulting in hospitalization, for which analytical evidence is most often missing or difficult to obtain. The lack of documentation, both analytical and clinical, of these files limits its expertise. As a result, medical knowledge, in particular clinical knowledge, progresses little which limits the efficiency of the management of these poisonings.
A 2015 pilot study on the Dax and Mont-de-Marsan (FERIATOX) fertilization sites on 27 patients showed that although several psychoactive substances have been identified in these patients (cocaine, ketamine, MDMA, cannabis, etc.) No DK was identified in this study. It is possible, however, that the profile of people who frequent ferias is different from that of music festivals, which explains the lack of identification of these substances in the FERIATOX study. To support this hypothesis, it seems important to renew this study on festive events of the type of music festival. The Garorock Festival (Marmande), held at the beginning of July, seems to be relevant for the study.
- Conditions
- Poisoning by Psychoactive Substances
- Being tested
- Sampling of a few drops of blood, lock of hair and urine
- Keywords
- Poisoning, Psychoactive substances
- Medical subject headings
- Poisoning
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Sampling of a few drops of blood, lock of hair and urineProcedure or surgery
Sampling of a few additional drops of blood to deposit them on blotting paper (DBS: Dried Blood Spot) ad hoc and to send this sample for analysis and identification of a possible toxic cause by psychoactive substance in relation to the clinical picture presented by the patient. An oriented capillary sampling is also performed if possible. Similarly a urine sample is taken if possible.
| Study group | Role | What they receive |
|---|---|---|
| Interventional arm | Experimental | * Sampling of a few additional drops of blood and sending this sample for analysis and identification of a possible toxic cause by psychoactive substance in relation to the clinical picture presented by the patient
* Oriented hair removal is also carried out if possible (small wick cut and not torn the size of a pencil mine of paper taken at the level of the occipital region). This technique has been used many times, and evaluates the previous consumption (memory consumption)
* A urine sample is taken if possible. Receives: Procedure: Sampling of a few drops of blood, lock of hair and urine |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of patients who have consumed new psychoactive substances
Number of patients who have consumed new psychoactive substances
Measured: baseline
Secondary outcomes (4)
number of toxidomas observed clinically
number of toxidomas observed clinically
Measured: Baseline
number of patients who have previously used new psychoactive substances (hair, urine
number of patients who have previously used new psychoactive substances (hair, urine
Measured: Baseline
number of classes of new psychoactive substances found in the analyzes
number of classes of new psychoactive substances found in the analyzes
Measured: baseline
severity evaluated secondarily from the clinical data sheets and according to poisoning severity score
severity evaluated secondarily from the clinical data sheets and according to poisoning severity score
Measured: baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jun 2017
- Study start30 Jun 2017
- Primary completion3 Jul 2017
- Study completion3 Jul 2017
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Poisoning by Psychoactive SubstancesStudies of the same condition, open and under way.
- More trials run by University Hospital, BordeauxThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- monocentric study
- Masking
- None (open label)
- Enrolment
- 25 participants (actual)
Sponsor and investigators
- Lead sponsor
- University Hospital, Bordeaux
- Sponsor type
- University, hospital or other
- Collaborators
- Regional Health Agency New Aquitaine
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03203213
- Sponsor's protocol ID
- CHUBX 2017/12
- Other IDs
- NCT03203213
- Acronym
- Musitox®
- Status last verified
- Jul 2017
- First submitted
- 27 Jun 2017
- Last updated
- 29 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Musitox® Project: Consumption of Psychoactive Substances at Music Festivals in Aquitaine
- ClinicalTrials.gov ID
- NCT03203213
- Acronym / sponsor ID
- Musitox® / CHUBX 2017/12
- Conditions
- Poisoning by Psychoactive Substances
- Keywords
- Poisoning, Psychoactive substances
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 25 participants (actual)
- Lead sponsor
- University Hospital, BordeauxUniversity, hospital or other
- Collaborators
- Regional Health Agency New Aquitaine
- Study start
- 30 Jun 2017 (actual)
- Primary completion
- 3 Jul 2017 (actual)
- Study completion
- 3 Jul 2017 (actual)
- First posted
- 29 Jun 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Poisoning by psychoactive substances is increasingly common in Europe and can be responsible for deaths. These substances, also called "festive drugs", circulate among other places in festive gatherings (night clubs, concerts, free music, feria, etc.). The main objective of this study is to determine the molecules that circulate in festive events in Aquitaine, in order to implement prevention actions by looking at whether the circulating substances vary with the style of event.
Detailed description
Poisoning by psychoactive substances is increasingly common in Europe and can be responsible for deaths. These substances, also called "festive drugs", circulate among other places in festive gatherings (night clubs, concerts, free music, feria, etc.).
There is also a significant increase in the number of new psychoactive substances (NSPs) whose toxicity is unknown: by 2014, 101 new substances were detected for the first time in Europe. These molecules, because of this regular and rapid emergence, are not included in the narcotics list, in the great majority of cases.
Poison control centers, as well as addictovigilance centers, are regularly called upon for serious poisoning resulting in hospitalization, for which analytical evidence is most often missing or difficult to obtain. The lack of documentation, both analytical and clinical, of these files limits its expertise. As a result, medical knowledge, in particular clinical knowledge, progresses little which limits the efficiency of the management of these poisonings.
A 2015 pilot study on the Dax and Mont-de-Marsan (FERIATOX) fertilization sites on 27 patients showed that although several psychoactive substances have been identified in these patients (cocaine, ketamine, MDMA, cannabis, etc.) No DK was identified in this study. It is possible, however, that the profile of people who frequent ferias is different from that of music festivals, which explains the lack of identification of these substances in the FERIATOX study. To support this hypothesis, it seems important to renew this study on festive events of the type of music festival. The Garorock Festival (Marmande), held at the beginning of July, seems to be relevant for the study.
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- monocentric study
| Arm | Type | Receives |
|---|---|---|
| Interventional arm | Experimental | Procedure: Sampling of a few drops of blood, lock of hair and urine* Sampling of a few additional drops of blood and sending this sample for analysis and identification of a possible toxic cause by psychoactive substance in relation to the clinical picture presented by the patient * Oriented hair removal is also carried out if possible (small wick cut and not torn the size of a pencil mine of paper taken at the level of the occipital region). This technique has been used many times, and evaluates the previous consumption (memory consumption) * A urine sample is taken if possible. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Any patient admitted to the Emergency Medical Post with neurological and / or behavioral disorders:
- agitated at the time of admission to the PMA or during surveillance at the LDC
- Oral Express Consent
- any patient who is in possession of an identity document proving his / her majority (over 18 years).
Key exclusion criteria (5 listed)
- Refusal of the patient to take a sample, or to participate in the study
- Minors (under 18 years of age)
- Pregnant women
- Breastfeeding women
- Patient who can not prove his / her age by the production of an identity document.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Sampling of a few drops of blood, lock of hair and urineSampling of a few additional drops of blood to deposit them on blotting paper (DBS: Dried Blood Spot) ad hoc and to send this sample for analysis and identification of a possible toxic cause by psychoactive substance in relation to the clinical picture presented by the patient. An oriented capillary sampling is also performed if possible. Similarly a urine sample is taken if possible. | Procedure or surgery | Interventional arm |
Primary outcome
Number of patients who have consumed new psychoactive substances
Time frame: baseline
Number of patients who have consumed new psychoactive substances
4 secondary outcomes
number of toxidomas observed clinically
Time frame: Baseline
number of patients who have previously used new psychoactive substances (hair, urine
Time frame: Baseline
number of classes of new psychoactive substances found in the analyzes
Time frame: baseline
severity evaluated secondarily from the clinical data sheets and according to poisoning severity score
Time frame: baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Sampling of a few drops of blood, lock of hair and urine in people with Poisoning by Psychoactive Substances, run by University Hospital, Bordeaux at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of patients who have consumed new psychoactive substances (time frame: baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 May 2026.