Childhood ObesityJBCNCT03217656
The Jiaxing Birth Cohort in China
An observational study of Childhood Obesity and Anemia, run by Zhejiang University at 1 site in China.
Trial summary
The Jiaxing Birth Cohort (JBC) is the largest prospective cohort study to explore prenatal risk factors, early life feeding practice and growth pattern/ adiposity in Chinese children.Between 1999 and 2013, 338 413 mother-child pairs were recruited in Jiaxing area in south-east China.Children of the recruited women… Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Childhood Obesity, Anemia, Pregnancy Complications
- How many people
- 500,000 participants
- Where
- 1 siteChina
- Study dates
- Jan 1999to Jan 2029
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Between 1999 and 2013, 363 416 pregnancies were followed from initial registration to the end of the pregnancy, with 25 003 children born to the above women having no further information (registration) after the birth. Therefore, a total of 338 413 live mother-child pairs registered at local clinics, and were enrolled in the Jiaxing Birth Cohort. Among the 338 413 children, there were 332 532 singletons, 2883 pairs of twins (n = 5766), 37 pairs of triplets (n= 111), and 1 pair of quadruplets (n = 4).
Who may be able to join
- Pregnant women came to clinic visit at one of the local hospitals during pregnancy at Jiaxing area
- Pregnant women were followed up during pregnancy and their children were born alive at local hospital or clinics
Who cannot join
- Those who did not want to participant
- The infant was dead at the birth
- Those pregnant mothers who dropped out during follow-up at pregnancy or moved out of the Jiaxing area
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Duo Li, PhD contact
Ju-Sheng Zheng, PhD contact
China1 site, 1 recruiting
- Recruiting
Zhejiang University
Hangzhou, Zhejiang, 310058
Duo Li, Ph.D., +86 571 88982024, duoli@zju.edu.cn
Duo Li, PhD
About this study
The Jiaxing Birth Cohort (JBC) is the largest prospective cohort study to explore prenatal risk factors, early life feeding practice and growth pattern/ adiposity in Chinese children.Between 1999 and 2013, 338 413 mother-child pairs were recruited in Jiaxing area in south-east China.Children of the recruited women were followed up at 1-2, 3, 6, 9 and 12 months of age, and subsequently followed up every 6 months to 36 months of age (toddler stage), and every year to 6-7 years of age before they went to school (pre-school stage). Follow-up rate was 70.8% at the toddler stage and 68.9% at the pre-school stage up to June 2013.
- Conditions
- Childhood Obesity, Anemia, Pregnancy Complications, Pregnancy; Hypertension, Feeding Behavior
- Being tested
- No intervention
- Medical subject headings
- Pediatric Obesity, Anemia, Pregnancy Complications, Hypertension, Pregnancy-Induced, Feeding Behavior
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No interventionOther
| Study group | Role | What they receive |
|---|---|---|
| Mother-child birth cohort | Not described Receives: Other: No intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
overweight and obesity
BMI-z-score was calculated from height and weight. BMI-z-score>1 was defined as overweight/obesity
Measured: Up to 6-7 years old for these children
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jul 2017
- Study startJan 1999
- Primary completionJan 2019 (estimated)
- Study completionJan 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Childhood ObesityStudies of the same condition, open and under way.
- More trials run by Zhejiang UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 500,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Zhejiang University
- Sponsor type
- University, hospital or other
- Collaborators
- Jiaxing Maternity and Child Health Care Hospital, Qingdao University, Westlake University
- Responsible party
- Principal investigator, Duo li, Zhejiang University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03217656
- Sponsor's protocol ID
- ZJU_JBC2013013
- Acronym
- JBC
- Status last verified
- Jan 2018
- First submitted
- 18 Jun 2017
- Last updated
- 23 Jan 2018
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Zheng JS, Liu H, Jiang J, Huang T, Wang F, Guan Y, Li D. Cohort Profile: The Jiaxing Birth Cohort in China. Int J Epidemiol. 2017 Oct 1;46(5):1382-1382g. doi: 10.1093/ije/dyw203. No abstract available.
PubMed 27940484
Study at a glance
From the registry record, last updated by the sponsor on 23 Jan 2018. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Jiaxing Birth Cohort in China
- ClinicalTrials.gov ID
- NCT03217656
- Acronym / sponsor ID
- JBC / ZJU_JBC2013013
- Conditions
- Childhood Obesity, Anemia, Pregnancy Complications, Pregnancy; Hypertension, Feeding Behavior
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 500,000 participants (estimated)
- Lead sponsor
- Zhejiang UniversityUniversity, hospital or other
- Collaborators
- Jiaxing Maternity and Child Health Care Hospital, Qingdao University, Westlake University
- Study start
- Jan 1999 (actual)
- Primary completion
- Jan 2019 (estimated)
- Study completion
- Jan 2029 (estimated)
- First posted
- 14 Jul 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The Jiaxing Birth Cohort (JBC) is the largest prospective cohort study to explore prenatal risk factors, early life feeding practice and growth pattern/ adiposity in Chinese children.Between 1999 and 2013, 338 413 mother-child pairs were recruited in Jiaxing area in south-east China.Children of the recruited women were followed up at 1-2, 3, 6, 9 and 12 months of age, and subsequently followed up every 6 months to 36 months of age (toddler stage), and every year to 6-7 years of age before they went to school (pre-school stage). Follow-up rate was 70.8% at the toddler stage and 68.9% at the pre-school stage up to June 2013.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Mother-child birth cohort | – | Other: No intervention |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Between 1999 and 2013, 363 416 pregnancies were followed from initial registration to the end of the pregnancy, with 25 003 children born to the above women having no further information (registration) after the birth. Therefore, a total of 338 413 live mother-child pairs registered at local clinics, and were enrolled in the Jiaxing Birth Cohort. Among the 338 413 children, there were 332 532 singletons, 2883 pairs of twins (n = 5766), 37 pairs of triplets (n= 111), and 1 pair of quadruplets (n = 4).
Key inclusion criteria (2 listed)
- Pregnant women came to clinic visit at one of the local hospitals during pregnancy at Jiaxing area
- Pregnant women were followed up during pregnancy and their children were born alive at local hospital or clinics
Key exclusion criteria (3 listed)
- Those who did not want to participant
- The infant was dead at the birth
- Those pregnant mothers who dropped out during follow-up at pregnancy or moved out of the Jiaxing area
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No intervention | Other | Mother-child birth cohort |
Primary outcome
overweight and obesity
Time frame: Up to 6-7 years old for these children
BMI-z-score was calculated from height and weight. BMI-z-score>1 was defined as overweight/obesity
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jan 2018.
- Background: PubMed 27940484Zheng JS, Liu H, Jiang J, Huang T, Wang F, Guan Y, Li D. Cohort Profile: The Jiaxing Birth Cohort in China. Int J Epidemiol. 2017 Oct 1;46(5):1382-1382g. doi: 10.1093/ije/dyw203. No abstract available.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Duo Li, PhD contact
Ju-Sheng Zheng, PhD contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Childhood Obesity and Anemia, run by Zhejiang University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 23 Jan 2018. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Duo Li, PhD (duoli@zju.edu.cn), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
overweight and obesity (time frame: Up to 6-7 years old for these children). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03217656, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jan 2018.