ObesityNCT03297931
Comparison of Pulse Chips and Commercial Snacks on Food Intake, Appetite and Blood Glucose in Healthy Young Adults
A study testing Corn Chips + Onion Dip, Yellow pea chip + hummus and Pinto bean chip + hummus in people with Obesity and Diabetes, run by University of Toronto at 1 site in Canada.
Trial summary
Consumers are often forced to eat fast, convenient foods and snacks ("eat on the go") in order to match the pace of their lifestyles. However, these snack options more often than not offer little health benefit to the consumer. Read more about this study
- Who is it for?
- Ages 18 to 45 yearsHealthy volunteers can take part
- What is being tested?
- Corn Chips + Onion Dip, Yellow pea chip + hummus and Pinto bean chip + hummus
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 26 participants
- Where
- 1 siteCanada
- Study dates
- 19 Jul 2017to 31 May 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Age: ≥18 and ≤45 years
- BMI: ≥ 18.5 and ≤ 29.9 kg/m2
- Fasting serum glucose: ≤ 5.6 mmol/L
- Willing to maintain habitual diet, physical activity pattern, and body weight throughout the trial.
- Willing to maintain current dietary supplement use throughout the trial. On test days, subject agrees not to take any dietary supplements until dismissal from the Department of Nutritional Sciences. Failure to comply will result in a rescheduled test visit.
- Willing to abstain from alcohol consumption for 24 h prior to all test visits.
- Willing to avoid vigorous physical activity for 24 h prior to all test visits.
- Understanding the study procedures and willing to provide informed consent to participate in the study and authorization to release relevant protected health information to the study investigator.
Who cannot join
- Fasting blood glucose > 5.6 mmol/L
- Smoking
- Thyroid problems
- Previous history of cardiovascular disease, diabetes, liver or kidney disease, inflammatory bowel disease, celiac disease, short bowel syndrome, any malabsorptive syndrome, pancreatitis, gallbladder or biliary disease.
- Presence of gastrointestinal disorder or surgeries within the past year.
- Consuming prescription or non-prescription drug, herbal or nutritional supplements known to affect blood glucose or that could affect the outcome of the study as per investigator's judgement.
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- Patients who have undergone bariatric surgery at any point.
- Known to be pregnant or lactating.
- Unwillingness or inability to comply with the experimental procedures
- Known intolerance, sensitivity or allergy to pulses or dairy.
- Extreme dietary habits (ie. Atkins diet, very high protein diets, etc.).
- Uncontrolled hypertension (systolic blood pressure ≥ 140 mm Hg or diastolic blood pressure ≥ 90 mm Hg) as defined by the average blood pressure measured at screening.
- Weight gain or loss of at least 10 lbs in previous three months.
- Excessive alcohol intake (more than 2 drinks per day or more than 9 drinks per week)
- Restrained Eaters
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of Roasted Pulse Snacks, Pulse Chips and Commercial Snacks on Post-prandial Food Intake, Appetite and Glycemic Response in Healthy Young Adults
Consumers are often forced to eat fast, convenient foods and snacks ("eat on the go") in order to match the pace of their lifestyles. However, these snack options more often than not offer little health benefit to the consumer. In fact, 55% of calories consumed by Canadians are ultra processed foods, which are limited in their nutrient profile and only offer empty calories. Subsequently, these foods lead the consumer to eat more and provides little to no feelings of satiety or satiation. the proposed objectives of the current project are to examine the physiological benefit(s) of consuming readily available pulse snacks and compare them to other commonly consumed snack varieties. This work aims to incentivize consumers to seek out pulses as valuable snacking options and highlight the benefit of including these as alternatives to other energy-dense snacks that lack the nutritional composition of pulses.
Read the detailed description
Hypothesis of the study: Inclusion of pulses as part of a snack will lower appetite and post-prandial glycemia (PPG) in comparison to commercial, commonly consumed non-pulse snacks.
Overall Objective of the study: To investigate and compare the effects of pulse and non-pulse snacks served as chips and dip on appetite and PPG in healthy adults.
Specific objectives of the study: To test the acute effects of different pulse snacks on: 1) PPG and appetite for three hours, and 2) food intake 1 hour following consumption of snacks.
- Being tested
- Corn Chips + Onion Dip, Yellow pea chip + hummus, Pinto bean chip + hummus, Pinto bean chip + onion dip, Yellow pea chip + onion dip
- Keywords
- Pulse, Snack, Post-prandial glycemia, Appetite, Food intake, Young adults, Satiety
- Medical subject headings
- Obesity, Diabetes Mellitus
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Corn Chips + Onion DipDietary supplement
Non-pulse chip + non-pulse dip
Yellow pea chip + hummusDietary supplement
Novel pulse chip + pulse spread
Pinto bean chip + hummusDietary supplement
Commercial pulse chip + pulse spread
Pinto bean chip + onion dipDietary supplement
Commercial pulse chip + non-pulse spread
Yellow pea chip + onion dipDietary supplement
Novel pulse chip + non-pulse spread
Corn chips + hummusDietary supplement
Non-pulse chip + pulse spread
| Study group | Role | What they receive |
|---|---|---|
| Commercial corn chips + Onion dip | Active comparator | Corn chips + onion dip Receives: Dietary Supplement: Corn Chips + Onion Dip |
| Commercial pulse chip + pulse spread | Experimental | Pinto bean chip + hummus Receives: Dietary Supplement: Pinto bean chip + hummus |
| Novel pulse chip + pulse spread | Experimental | Yellow pea chip + hummus Receives: Dietary Supplement: Yellow pea chip + hummus |
| Commercial pulse chip + non-pulse spread | Experimental | Pinto bean chip + onion dip Receives: Dietary Supplement: Pinto bean chip + onion dip |
| Novel pulse chip + non-pulse spread | Experimental | Yellow pea chip + onion dip Receives: Dietary Supplement: Yellow pea chip + onion dip |
| Non-pulse chip + pulse spread | Experimental | Corn chips + hummus Receives: Dietary Supplement: Corn chips + hummus |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in blood glucose levels
Each participant will attend 6 sessions in total (randomized 6-arm cross-over design)
Measured: Starting at the beginning of each session (0 minutes, before consumption of treatment) and every 15 - 30 minutes up to 190 minutes (time of completion of each session)
Subjective appetite
Measured using Visual Analog Scales (VAS)
Measured: Measured every 15-30 minutes up to 190 minutes
Food intake
Food intake is measured by the amount of pizza (in grams) consumed during the 20 minute period (pizza is served ad libitum)
Measured: 65 minutes after completion of treatment, 20 minutes is allocated to allow for pizza consumption
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Sep 2017
- Study start19 Jul 2017
- Primary completion31 Dec 2023
- Study completion31 May 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ObesityStudies of the same condition, open and under way.
- More trials run by University of TorontoThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 26 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Toronto
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, G. Harvey Anderson, University of Toronto
- Investigators
- Harvey G Anderson, PhD, Principal investigator, University of Toronto
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03297931
- Sponsor's protocol ID
- SPG_Snack Study
- Status last verified
- Mar 2025
- First submitted
- 25 Sep 2017
- Last updated
- 28 Mar 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Mar 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Roasted Pulse Snacks, Pulse Chips and Commercial Snacks on Post-prandial Food Intake, Appetite and Glycemic Response in Healthy Young Adults
- ClinicalTrials.gov ID
- NCT03297931
- Acronym / sponsor ID
- SPG_Snack Study
- Keywords
- Pulse, Snack, Post-prandial glycemia, Appetite, Food intake, Young adults, Satiety
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 26 participants (actual)
- Lead sponsor
- University of TorontoUniversity, hospital or other
- Study start
- 19 Jul 2017 (actual)
- Primary completion
- 31 Dec 2023 (actual)
- Study completion
- 31 May 2024 (actual)
- First posted
- 29 Sep 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Consumers are often forced to eat fast, convenient foods and snacks ("eat on the go") in order to match the pace of their lifestyles. However, these snack options more often than not offer little health benefit to the consumer. In fact, 55% of calories consumed by Canadians are ultra processed foods, which are limited in their nutrient profile and only offer empty calories. Subsequently, these foods lead the consumer to eat more and provides little to no feelings of satiety or satiation. the proposed objectives of the current project are to examine the physiological benefit(s) of consuming readily available pulse snacks and compare them to other commonly consumed snack varieties. This work aims to incentivize consumers to seek out pulses as valuable snacking options and highlight the benefit of including these as alternatives to other energy-dense snacks that lack the nutritional composition of pulses.
Detailed description
Hypothesis of the study: Inclusion of pulses as part of a snack will lower appetite and post-prandial glycemia (PPG) in comparison to commercial, commonly consumed non-pulse snacks.
Overall Objective of the study: To investigate and compare the effects of pulse and non-pulse snacks served as chips and dip on appetite and PPG in healthy adults.
Specific objectives of the study: To test the acute effects of different pulse snacks on: 1) PPG and appetite for three hours, and 2) food intake 1 hour following consumption of snacks.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (participant)
- Number of arms
- 6
| Arm | Type | Receives |
|---|---|---|
| Commercial corn chips + Onion dip | Active comparator | Dietary Supplement: Corn Chips + Onion DipCorn chips + onion dip |
| Commercial pulse chip + pulse spread | Experimental | Dietary Supplement: Pinto bean chip + hummusPinto bean chip + hummus |
| Novel pulse chip + pulse spread | Experimental | Dietary Supplement: Yellow pea chip + hummusYellow pea chip + hummus |
| Commercial pulse chip + non-pulse spread | Experimental | Dietary Supplement: Pinto bean chip + onion dipPinto bean chip + onion dip |
| Novel pulse chip + non-pulse spread | Experimental | Dietary Supplement: Yellow pea chip + onion dipYellow pea chip + onion dip |
| Non-pulse chip + pulse spread | Experimental | Dietary Supplement: Corn chips + hummusCorn chips + hummus |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (8 listed)
- Age: ≥18 and ≤45 years
- BMI: ≥ 18.5 and ≤ 29.9 kg/m2
- Fasting serum glucose: ≤ 5.6 mmol/L
- Willing to maintain habitual diet, physical activity pattern, and body weight throughout the trial.
- Willing to maintain current dietary supplement use throughout the trial. On test days, subject agrees not to take any dietary supplements until dismissal from the Department of Nutritional Sciences. Failure to comply will result in a rescheduled test visit.
Key exclusion criteria (15 listed)
- Fasting blood glucose > 5.6 mmol/L
- Smoking
- Thyroid problems
- Previous history of cardiovascular disease, diabetes, liver or kidney disease, inflammatory bowel disease, celiac disease, short bowel syndrome, any malabsorptive syndrome, pancreatitis, gallbladder or biliary disease.
- Presence of gastrointestinal disorder or surgeries within the past year.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Corn Chips + Onion DipNon-pulse chip + non-pulse dip | Dietary supplement | Commercial corn chips + Onion dip |
| Yellow pea chip + hummusNovel pulse chip + pulse spread | Dietary supplement | Novel pulse chip + pulse spread |
| Pinto bean chip + hummusCommercial pulse chip + pulse spread | Dietary supplement | Commercial pulse chip + pulse spread |
| Pinto bean chip + onion dipCommercial pulse chip + non-pulse spread | Dietary supplement | Commercial pulse chip + non-pulse spread |
| Yellow pea chip + onion dipNovel pulse chip + non-pulse spread | Dietary supplement | Novel pulse chip + non-pulse spread |
| Corn chips + hummusNon-pulse chip + pulse spread | Dietary supplement | Non-pulse chip + pulse spread |
Primary outcome
Change in blood glucose levels
Time frame: Starting at the beginning of each session (0 minutes, before consumption of treatment) and every 15 - 30 minutes up to 190 minutes (time of completion of each session)
Each participant will attend 6 sessions in total (randomized 6-arm cross-over design)
Subjective appetite
Time frame: Measured every 15-30 minutes up to 190 minutes
Measured using Visual Analog Scales (VAS)
Food intake
Time frame: 65 minutes after completion of treatment, 20 minutes is allocated to allow for pizza consumption
Food intake is measured by the amount of pizza (in grams) consumed during the 20 minute period (pizza is served ad libitum)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Mar 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Harvey G Anderson, PhD principal investigator
University of Toronto
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Corn Chips + Onion Dip, Yellow pea chip + hummus and Pinto bean chip + hummus in people with Obesity and Diabetes, run by University of Toronto at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 15 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in blood glucose levels (time frame: Starting at the beginning of each session (0 minutes, before consumption of treatment) and every 15 - 30 minutes up to 190 minutes (time of completion of each session)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Mar 2025.