Adolescent and Young Adult (AYA) Cancer SurvivorsNCT03363711
AYA STEPS RCT: AYA Self-Management Via Texting, Education & Plans for Survivors
An observational study of Adolescent and Young Adult (AYA) Cancer Survivors, run by Abramson Cancer Center at Penn Medicine at 1 site in United States.
Trial summary
The proposed project will leverage two programs of research at UPenn and CHOP that are delivering technology-based interventions to adolescent and young adult (AYA) cancer survivors. In the proposed study, all AYA survivors will receive a care plan via a tool (Smart-ALACC). Read more about this study
- Who is it for?
- Ages 15 to 29 years
- Conditions the study is for
- Adolescent and Young Adult (AYA) Cancer Survivors
- What is being tested?
- AYA STEPS
- How many people
- 25 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Mar 2017to 31 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 15 to 29 years
- All sexes
- No healthy volunteers
- Child, Adult
Study population: 15-29 year olds with a history of malignant cancer diagnosis.
Who may be able to join
- AYA is 15-29 year old with a history of a malignant cancer diagnosis;
- Completed cancer treatment and are currently in remission or receiving cancer survivorship care;
- Seen for follow-up oncology care at CHOP or Penn;
- For AYA less than 18 years old, must have a caregiver to provide informed consent.
Who cannot join
- Cognitive impairments that would limit AYA ability to independently care for health as determined by the medical team.
- Absence of the inclusion criteria
Trial locations and contacts
1 site in 1 country.
United States1 site
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104
About this study
The proposed project will leverage two programs of research at UPenn and CHOP that are delivering technology-based interventions to adolescent and young adult (AYA) cancer survivors.
In the proposed study, all AYA survivors will receive a care plan via a tool (Smart-ALACC). They will then be randomized to receive (or not) a mobile health application (AYA STEPS) that will provide tailored messages to enhance uptake of their care plan.
- Being tested
- AYA STEPS
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
AYA STEPSOther
a mobile health application
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of Completed mobile data and questionnaires
Measured: 10 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Dec 2017
- Study start1 Mar 2017
- Primary completion1 Dec 2019
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Adolescent and Young Adult (AYA) Cancer SurvivorsStudies of the same condition, open and under way.
- More trials run by Abramson Cancer Center at Penn MedicineThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 25 participants (actual)
Sponsor and investigators
- Lead sponsor
- Abramson Cancer Center at Penn Medicine
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Christine Hill-Kayser, MD, Principal investigator, Abramson Cancer Center at Penn Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03363711
- Sponsor's protocol ID
- UPCC 26916
- Status last verified
- Jan 2026
- First submitted
- 1 Dec 2017
- Last updated
- 8 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Darabos K, Deatrick JA, Wolk CB, O'Hagan B, King-Dowling S, Szalda D, Hobbie W, Barakat LP, Hill-Kayser C, Schwartz LA. Perspectives on Care Plans for Adolescent and Young Adult Survivors of Childhood Cancer: A Qualitative Evaluation of Survivors, Caregivers, and Oncology and Primary Care Practitioners. J Adolesc Young Adult Oncol. 2026 Apr;15(2):115-123. doi: 10.1177/21565333251362113. Epub 2026 Mar 10.
PubMed 40719621Psihogios AM, King-Dowling S, O'Hagan B, Darabos K, Maurer L, Young J, Fleisher L, Barakat LP, Szalda D, Hill-Kayser CE, Schwartz LA. Contextual Predictors of Engagement in a Tailored mHealth Intervention for Adolescent and Young Adult Cancer Survivors. Ann Behav Med. 2021 Nov 18;55(12):1220-1230. doi: 10.1093/abm/kaab008.
PubMed 33674863
Study at a glance
From the registry record, last updated by the sponsor on 8 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- AYA STEPS RCT: AYA Self-Management Via Texting, Education & Plans for Survivors
- ClinicalTrials.gov ID
- NCT03363711
- Acronym / sponsor ID
- UPCC 26916
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 25 participants (actual)
- Lead sponsor
- Abramson Cancer Center at Penn MedicineUniversity, hospital or other
- Study start
- 1 Mar 2017 (actual)
- Primary completion
- 1 Dec 2019 (actual)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 6 Dec 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The proposed project will leverage two programs of research at UPenn and CHOP that are delivering technology-based interventions to adolescent and young adult (AYA) cancer survivors.
In the proposed study, all AYA survivors will receive a care plan via a tool (Smart-ALACC). They will then be randomized to receive (or not) a mobile health application (AYA STEPS) that will provide tailored messages to enhance uptake of their care plan.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 15 to 29 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
- Study population
- 15-29 year olds with a history of malignant cancer diagnosis.
Key inclusion criteria (4 listed)
- AYA is 15-29 year old with a history of a malignant cancer diagnosis;
- Completed cancer treatment and are currently in remission or receiving cancer survivorship care;
- Seen for follow-up oncology care at CHOP or Penn;
- For AYA less than 18 years old, must have a caregiver to provide informed consent.
Key exclusion criteria (2 listed)
- Cognitive impairments that would limit AYA ability to independently care for health as determined by the medical team.
- Absence of the inclusion criteria
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| AYA STEPSa mobile health application | Other | – |
Primary outcome
Number of Completed mobile data and questionnaires
Time frame: 10 years
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jan 2026.
- Derived from this study: PubMed 40719621Darabos K, Deatrick JA, Wolk CB, O'Hagan B, King-Dowling S, Szalda D, Hobbie W, Barakat LP, Hill-Kayser C, Schwartz LA. Perspectives on Care Plans for Adolescent and Young Adult Survivors of Childhood Cancer: A Qualitative Evaluation of Survivors, Caregivers, and Oncology and Primary Care Practitioners. J Adolesc Young Adult Oncol. 2026 Apr;15(2):115-123. doi: 10.1177/21565333251362113. Epub 2026 Mar 10.
- Derived from this study: PubMed 33674863Psihogios AM, King-Dowling S, O'Hagan B, Darabos K, Maurer L, Young J, Fleisher L, Barakat LP, Szalda D, Hill-Kayser CE, Schwartz LA. Contextual Predictors of Engagement in a Tailored mHealth Intervention for Adolescent and Young Adult Cancer Survivors. Ann Behav Med. 2021 Nov 18;55(12):1220-1230. doi: 10.1093/abm/kaab008.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Christine Hill-Kayser, MD principal investigator
Abramson Cancer Center at Penn Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Adolescent and Young Adult (AYA) Cancer Survivors, run by Abramson Cancer Center at Penn Medicine at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 8 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of Completed mobile data and questionnaires (time frame: 10 years). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03363711, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jan 2026.