DepressionHLGDepNCT03414606
Social Behavior in Depression
An observational study of Depression, run by Beijing Normal University at 1 site in China.
Trial summary
In the project, investigators basically plan to test the difference in social behavior and social cognition between depressive patients and healthy individuals. To test this, investigators plan to use traditional or novel behavioral experiment paradigms to target various behaviors. Read more about this study
- Who is it for?
- Ages 18 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Depression
- How many people
- 25 participants
- Where
- 1 siteChina
- Study dates
- 1 Feb 2017to 1 Mar 2018
- How long will I take part?
- 1 Month
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Individuals diagnosed with depression and healthy control
Who may be able to join
- Age range between 18 and 60
- Education experience above high school
- Score for Hamilton's Depression Scale >=17
- Diagnosis of depression through Scid
Who cannot join
- Undergoing electric shock treatment in 3 months
- Excluding those who with bipolar disorder
- Excluding those who with postpartum depression
- Excluding those who with hysteria
Trial locations and contacts
1 site in 1 country.
China1 site, 1 recruiting
- Recruiting
Huilongguan Hospital
Beijing
Yina Ma, Doctor
Yina Ma, Doctor
About this study
In the project, investigators basically plan to test the difference in social behavior and social cognition between depressive patients and healthy individuals. To test this, investigators plan to use traditional or novel behavioral experiment paradigms to target various behaviors.
- Conditions
- Depression
- Medical subject headings
- Depression
What is being measured
The primary outcome is the main question the study is designed to answer.
Prosocial behavior
The prosocial behavior will be assessed by conventional economic games, including dictator game, message game, and ultimatum game.
Measured: Baseline
Cognitive flexibility
Cognitive flexibility will be assessed by psychological cognitive paradigm, i.e. reversal learning paradigm. The participants will be asked to choose the item with high probability to win reward.
Measured: Baseline
Valuation of social information
The valuation of social information was measured by psychological paradigm, developed from animal studies, called "pay-per-view". The participants will be asked make decision about more social information or more monetary reward.
Measured: Baseline
Optimism bias
Participants will complete two sessions of life event estimation, i.e. estimating their likelihood of experiencing each event on a self-paced basis.
Measured: Baseline
Emotion recognition
After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients.
Measured: Baseline
Model-free & model-based tendency
Participants will be asked to complete a two-stage task, by choosing the stimuli with high probability to obtain reward.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Jan 2018
- Study start1 Feb 2017
- Primary completion16 Feb 2018 (estimated)
- Study completion1 Mar 2018 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for DepressionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 25 participants (estimated)
- Target duration
- 1 Month
Sponsor and investigators
- Lead sponsor
- Beijing Normal University
- Sponsor type
- University, hospital or other
- Collaborators
- Huilongguan Hospital
- Responsible party
- Principal investigator, ma, yina, Beijing Normal University
- Investigators
- Yina Ma, Doctor, Study chair, Beijing Normal University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03414606
- Sponsor's protocol ID
- HLGdepression
- Acronym
- HLGDep
- Status last verified
- Feb 2018
- First submitted
- 22 Jan 2018
- Last updated
- 6 Feb 2018
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Feb 2018. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Social Behavior in Depression
- ClinicalTrials.gov ID
- NCT03414606
- Acronym / sponsor ID
- HLGDep / HLGdepression
- Conditions
- Depression
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 25 participants (estimated)
- Lead sponsor
- Beijing Normal UniversityUniversity, hospital or other
- Collaborators
- Huilongguan Hospital
- Study start
- 1 Feb 2017 (actual)
- Primary completion
- 16 Feb 2018 (estimated)
- Study completion
- 1 Mar 2018 (estimated)
- First posted
- 30 Jan 2018 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In the project, investigators basically plan to test the difference in social behavior and social cognition between depressive patients and healthy individuals. To test this, investigators plan to use traditional or novel behavioral experiment paradigms to target various behaviors.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Target follow-up
- 1 Month
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Individuals diagnosed with depression and healthy control
Key inclusion criteria (4 listed)
- Age range between 18 and 60
- Education experience above high school
- Score for Hamilton's Depression Scale >=17
- Diagnosis of depression through Scid
Key exclusion criteria (4 listed)
- Undergoing electric shock treatment in 3 months
- Excluding those who with bipolar disorder
- Excluding those who with postpartum depression
- Excluding those who with hysteria
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Prosocial behavior
Time frame: Baseline
The prosocial behavior will be assessed by conventional economic games, including dictator game, message game, and ultimatum game.
Cognitive flexibility
Time frame: Baseline
Cognitive flexibility will be assessed by psychological cognitive paradigm, i.e. reversal learning paradigm. The participants will be asked to choose the item with high probability to win reward.
Valuation of social information
Time frame: Baseline
The valuation of social information was measured by psychological paradigm, developed from animal studies, called "pay-per-view". The participants will be asked make decision about more social information or more monetary reward.
Optimism bias
Time frame: Baseline
Participants will complete two sessions of life event estimation, i.e. estimating their likelihood of experiencing each event on a self-paced basis.
Emotion recognition
Time frame: Baseline
After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients.
Model-free & model-based tendency
Time frame: Baseline
Participants will be asked to complete a two-stage task, by choosing the stimuli with high probability to obtain reward.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Feb 2018.
Related trials for Depression
Recruiting
Affective Cognitive Training in Mood Disorders and High-risk Relatives
Major Depressive Disorder (MDD), Bipolar Disorder (BD)
Active, not recruiting
AI Mental Health Tool vs. Psychoeducation Control
Depressive Disorder, Depressive Symptoms
Not yet recruitingObservational study
The Effects of Extreme Prematurity on Parenting
Depression Disorder, Post Traumatic Stress Disorder PTSD
Recruiting
Marine Lipids Ease Painful TMD
Temporomandibular Disorder (TMD)
Recruiting
Restoring Emotional Needs With Exogenous Ketones for Women With Postpartum Depression
Postpartum Depression (PPD)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Yina Ma, Doctor study chair
Beijing Normal University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Depression, run by Beijing Normal University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 6 Feb 2018. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Yina Ma, Doctor (+8613810258647, yma@bnu.edu.cn), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Prosocial behavior (time frame: Baseline). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Feb 2018.