Morbid ObesityPRECOSNCT03517072
Determinants of the Long-Term Success of Bariatric Surgery
An observational study of Morbid Obesity and Bariatric Surgery Candidate, run by University Hospital, Lille at 4 sites in France.
Trial summary
The management of obesity is based on a multidisciplinary approach and justifies the use of surgery in patients with the most severe forms. Surgery for obesity or bariatric surgery generally allows rapid and significant weight loss however it is associated with significant risks, and its long-term results remain… Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Morbid Obesity, Bariatric Surgery Candidate
- How many people
- 1,000 participants
- Where
- 4 sitesFrance
- Study dates
- 31 Jul 2018to Jan 2027
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Child, Adult, Older adult
Study population: The project relies on the network of Specialised Centres for the Management of Severe Obesity (Lille, Arras, Boulogne, Valenciennes). Patients with severe obesity who underwent bariatric surgery 5 years ago will be included in each of the centre, during the usual multidisciplinary care visit.
Who may be able to join
- Patients who received bariatric surgery 5 years ago.
Who cannot join
- Refusal to participate in the study,
- Unable to receive informed information,
- Unable to participate in the study
Trial locations and contacts
4 sites in 1 country. Contact the study team or a site near you to ask about taking part.
France4 sites, 4 recruiting
- Recruiting
CH ARRAS
Arras
- Recruiting
Ch Boulogne-Sur-Mer
Boulogne-sur-Mer
0321993333
- Recruiting
Hôpital Claude Huriez, CHU
Lille
François Pattou, MD,PhD
- Recruiting
Ch de Valenciennes
Valenciennes
About this study
Official title: Determinants of the Long-Term Success of Bariatric Surgery "- Multicenter Regional Observational Study: Regional Multicentre Prospective Study
The management of obesity is based on a multidisciplinary approach and justifies the use of surgery in patients with the most severe forms. Surgery for obesity or bariatric surgery generally allows rapid and significant weight loss however it is associated with significant risks, and its long-term results remain heterogeneous and unpredictable. Long-term data will clarify the role of different types of bariatric surgery in surgical strategy, improve patient information and identify predictors of failure in order to provide personalised and tailored surgery for each candidate .
Read the detailed description
Currently, there is insufficient data to determine the persistence over time of the positive results of bariatric surgery on weight loss. Moreover, there is no consensus or criteria for choosing one surgical weight loss procedure over another. The best choice for one patient may not be the most appropriate for another.
The results of this project will allow to better select obese patients likely to benefit from bariatric surgery, and to further personalise the management of severe obesity.
- Conditions
- Morbid Obesity, Bariatric Surgery Candidate
- Medical subject headings
- Obesity, Morbid
What is being measured
The primary outcome is the main question the study is designed to answer.
Success rate in terms of weight loss
Rate of patients who lost at least 20 of their initial body weight
Measured: at 5 years after bariatric surgery
Secondary outcomes (4)
Success rate in terms of weight loss according to type of bariatric surgery
Rate of patients who lost at least 20 of their initial body weight at 1 year according to type of bariatric surgery (Gastric by-pass in Y or Omega, sleeve gastrectomy, and gastric band)
Measured: at 1 year after bariatric surgery
Success rate in terms of weight loss according to type of bariatric surgery
Rate of patients who lost at least 20 of their initial body weight at 5 years according to type of bariatric surgery (Gastric by-pass in Y or Omega, sleeve gastrectomy, and gastric band)
Measured: at 5 years after bariatric surgery
Rate of re- interventions related to bariatric surgery
Evaluation of re-interventions following bariatric surgery
Measured: 5 years
Lost rate seen
Evaluation of lost to follow-up
Measured: at 5 years after bariatric surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 May 2018
- Study start31 Jul 2018
- Primary completionJan 2027 (estimated)
- Study completionJan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Morbid ObesityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 1,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Lille
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- François PATTOU, MD,PhD, Principal investigator, University Hospital, Lille
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03517072
- Sponsor's protocol ID
- 2016_24
- Other IDs
- 2016-A02058-43
- Acronym
- PRECOS
- Status last verified
- May 2026
- First submitted
- 24 Apr 2018
- Last updated
- 22 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No