HealthyNCT03636854
Quadriceps Concentric vs Eccentric
A study testing Concentric exercises and Eccentric exercises in people with Healthy, run by Dokuz Eylul University at 1 site in Turkey (Türkiye).
Trial summary
The aim of the study is to compare the effects of concentric and eccentric exercises on muscle strength, muscle thickness and balance in healthy Individuals. Participants will randomly be divided into 2 groups: Concentric exercise (CE) group, eccentric exercise (EE) group. Read more about this study
- Who is it for?
- Ages 18 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- Concentric exercises and Eccentric exercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Mar 2018to 28 May 2019
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Age between 18-25
- Healthy individuals
- Able to read, write and understand Turkish
- Willing and able to attend study
Who cannot join
- Any neurological, musculoskeletal or vascular disease in any of the lower extremity
- Having lower extremity musculoskeletal pain
- Previous history of surgery in any of the lower extremity
- Mental and cognitive disorders that would seriously affect cooperation
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Different Izotonic Quadriceps Exercise Training on Muscle Strength, Muscle Thickness and Balance in Healthy Individuals
The aim of the study is to compare the effects of concentric and eccentric exercises on muscle strength, muscle thickness and balance in healthy Individuals. Participants will randomly be divided into 2 groups: Concentric exercise (CE) group, eccentric exercise (EE) group. Concentric exercise group will be doing 2 concentric exercises and eccentric exercise group will be doing 2 eccentric exercise for 8 weeks. The evaluations will be repeated after 8 weeks of training to reveal the effects of concentric and eccentric exercises.
- Conditions
- Healthy
- Being tested
- Concentric exercises, Eccentric exercises
- Keywords
- Muscle thickness, muscle strength, hop Test, Balance, performance
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Concentric exercisesOther
Resistance concentric straight leg raise and knee extension will be done.
Eccentric exercisesOther
Resistance eccentric straight leg raise and knee extension will be done.
| Study group | Role | What they receive |
|---|---|---|
| Concentric Exercises | Experimental | 2 different concentric exercises will be done 3 times a week for 8 weeks. Receives: Other: Concentric exercises |
| Eccentric Exercises | Experimental | 2 different eccentric exercises will be done 3 times a week for 8 weeks. Receives: Other: Eccentric exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in muscle thickness
Change in muscle thickness will be measured by using Ultrasound
Measured: Before training and after 8 weeks of training
Secondary outcomes (3)
Change in muscle strength
Change in muscle strength will be assessed by using hand-held dynamometer.
Measured: Before training and after 8 weeks of training
Change in balance
Change in balance will be measured by using Biodex Balance System.
Measured: Before training and after 8 weeks of training
Change in function
Change in function will be measured by using single leg hop test
Measured: Before training and after 8 weeks of training
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Aug 2018
- Study start15 Mar 2018
- Primary completion15 Apr 2019
- Study completion28 May 2019
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Dokuz Eylul University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Emrullah ALKAN, Dokuz Eylul University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03636854
- Sponsor's protocol ID
- ConEcc
- Status last verified
- Jul 2020
- First submitted
- 16 Aug 2018
- Last updated
- 7 Jul 2020
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Jul 2020. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Different Izotonic Quadriceps Exercise Training on Muscle Strength, Muscle Thickness and Balance in Healthy Individuals
- ClinicalTrials.gov ID
- NCT03636854
- Acronym / sponsor ID
- ConEcc
- Conditions
- Healthy
- Keywords
- Muscle thickness, muscle strength, hop Test, Balance, performance
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Dokuz Eylul UniversityUniversity, hospital or other
- Study start
- 15 Mar 2018 (actual)
- Primary completion
- 15 Apr 2019 (actual)
- Study completion
- 28 May 2019 (actual)
- First posted
- 17 Aug 2018 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of the study is to compare the effects of concentric and eccentric exercises on muscle strength, muscle thickness and balance in healthy Individuals. Participants will randomly be divided into 2 groups: Concentric exercise (CE) group, eccentric exercise (EE) group. Concentric exercise group will be doing 2 concentric exercises and eccentric exercise group will be doing 2 eccentric exercise for 8 weeks. The evaluations will be repeated after 8 weeks of training to reveal the effects of concentric and eccentric exercises.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Concentric Exercises | Experimental | Other: Concentric exercises2 different concentric exercises will be done 3 times a week for 8 weeks. |
| Eccentric Exercises | Experimental | Other: Eccentric exercises2 different eccentric exercises will be done 3 times a week for 8 weeks. |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Age between 18-25
- Healthy individuals
- Able to read, write and understand Turkish
- Willing and able to attend study
Key exclusion criteria (4 listed)
- Any neurological, musculoskeletal or vascular disease in any of the lower extremity
- Having lower extremity musculoskeletal pain
- Previous history of surgery in any of the lower extremity
- Mental and cognitive disorders that would seriously affect cooperation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Concentric exercisesResistance concentric straight leg raise and knee extension will be done. | Other | Concentric Exercises |
| Eccentric exercisesResistance eccentric straight leg raise and knee extension will be done. | Other | Eccentric Exercises |
Primary outcome
Change in muscle thickness
Time frame: Before training and after 8 weeks of training
Change in muscle thickness will be measured by using Ultrasound
3 secondary outcomes
Change in muscle strength
Time frame: Before training and after 8 weeks of training
Change in balance
Time frame: Before training and after 8 weeks of training
Change in function
Time frame: Before training and after 8 weeks of training
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Jul 2020.
- Individual participant dataSharing planned: No
Related trials for Healthy
Not yet recruitingPhase 1
A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy Volunteers
Oral Ulcer, Oral Mucositis
Not yet recruiting
SUVY VerSus SAccharose (SUVISA)
Healthy Volunteers, Erythritol
RecruitingPhase 1
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Children
Seasonal Influenza
Not yet recruitingObservational study
Microneurographic Assessment of Peripheral Nerves in Healthy Volunteers and Individuals With Sensory Dysfunction Caused by Inherited Mutations in the PIEZO2 Gene
PIEZO2-Deficiency Syndrome
Enrolling by invitationObservational study
Connors Protocol for the Management and Use of Stored Human Specimens (Stored Human Specimens)
Healthy Volunteer Samples
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Concentric exercises and Eccentric exercises in people with Healthy, run by Dokuz Eylul University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 7 Jul 2020. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in muscle thickness (time frame: Before training and after 8 weeks of training). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Jul 2020.