Catheter AblationJ-ABNCT03729232
Japanese Catheter Ablation Registry
An observational study of Catheter Ablation and Cardiac Arrhythmias, run by National Cerebral and Cardiovascular Center, Japan at 1 site in Japan.
Trial summary
Japanese Cather Ablation (J-AB) Registry is a voluntary nationwide registry, performed by Japanese Heart Rhythm Society, collaborated with the National Cerebral and Cardiovascular Center. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Catheter Ablation, Cardiac Arrhythmias
- How many people
- 400,000 participants
- Where
- 1 siteJapan
- Study dates
- 1 Jul 2017to 31 Mar 2030
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Inpatients
Who may be able to join
- Patients treated with catheter ablation in Japan
Who cannot join
- Patients who refused to consent
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Japan1 site, 1 recruiting
- Recruiting
National Cerebral and Cardiovascular Center
Suita, Osaka, 564-8565
Kengo Kusano, MD, PhD, +81-6-6170-1070, kusanokengo@ncvc.go.jp
Misa Takegami, PhD, MPH, +81-6-6170-1070, takegami@ncvc.go.jp
About this study
Japanese Cather Ablation (J-AB) Registry is a voluntary nationwide registry, performed by Japanese Heart Rhythm Society, collaborated with the National Cerebral and Cardiovascular Center. The objectives of this registry are to observe and describe developments in the catheter ablation treatment of arrhythmia in Japan and to provide reliable information on the type of activity performed and the facilities available in Japanese arrhythmia units.
Read the detailed description
Japanese Cather Ablation (J-AB) Registry is a nationwide, multicenter, observational registry, performed by Japanese Heart Rhythm Society, collaborated with National Cerebral and Cardiovascular Center.
This study is a voluntary nationwide registry and data are collected prospectively using a Research Electronic Data Capture (REDCap) system. Detailed data collection including antiarrhythmic medication is also performed at every September. The acute success rate at discharge and the complications associated with ablation procedure will be collected in all cases. Major bleeding events are defined according to Bleeding Academic Research Consortium criteria. Based on the provided information, the annual incidence and predictive factors for outcome will be investigated by the event assessment committee.
- Conditions
- Catheter Ablation, Cardiac Arrhythmias
- Keywords
- Catheter Ablation, Cardiac Arrhythmias, Registry, Complication, REDCap
- Medical subject headings
- Arrhythmias, Cardiac
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of patients with recurrence of targeted arrhythmia
Measured: Through discharge from hospital, approximately up to 1 weeks
Secondary outcomes (2)
Number of deaths
All-cause death, cardiovascular death, and procedure-related death
Measured: Through discharge from hospital, approximately up to 1 weeks
Number of patients with treatment-related complications
Bleeding events, embolic events, other all complications. Major bleeding events are defined according to Bleeding Academic Research Consortium criteria.
Measured: 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Nov 2018
- Study start1 Jul 2017
- Primary completion31 Mar 2030 (estimated)
- Study completion31 Mar 2030 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Catheter AblationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Prospective
- Enrolment
- 400,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Cerebral and Cardiovascular Center, Japan
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Kengo Kusano, National Cerebral and Cardiovascular Center, Japan
- Investigators
- Teiichi Yamane, MD, PhD, Principal investigator, The Jikei University School of MedicineKengo Kusano, MD, PhD, Principal investigator, National Cerebral and Cardiovascular Center, Japan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03729232
- Sponsor's protocol ID
- M28-114
- Other IDs
- UMIN000028288
- Acronym
- J-AB
- Status last verified
- Nov 2023
- First submitted
- 31 Oct 2018
- Last updated
- 13 Nov 2023
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Matsuda Y, Masuda M, Kanaoka K, Mano T, Inoue K, Yamashita S, Iwasaki YK, Nakamura K, Nagashima K, Miyamoto K, Satomi K, Takatsuki S, Kusano K, Yamane T, Shimizu W. Real-World Outcomes of Repeat Ablation Strategies for Atrial Fibrillation: Insights From the Japanese Catheter Ablation Registry. J Arrhythm. 2025 Sep 22;41(5):e70200. doi: 10.1002/joa3.70200. eCollection 2025 Oct.
PubMed 40995616Goto K, Miyazaki S, Tonegawa-Kuji R, Kanaoka K, Yamashita S, Sasano T, Iwanaga Y, Nakai M, Inoue K, Iwasaki YK, Nagashima K, Nakamura K, Masuda M, Miyamaoto K, Satomi K, Takatsuki S, Kusano K, Yamane T, Shimizu W. Efficacy and Safety of Second Sessions of Catheter Ablation for Idiopathic Premature Ventricular Contractions: From the Nationwide Japan Catheter Ablation Registry. J Arrhythm. 2025 Aug 25;41(4):e70181. doi: 10.1002/joa3.70181. eCollection 2025 Aug.
PubMed 40861252Oikawa J, Fukaya H, Kanaoka K, Niwano S, Miyamoto K, Iwanaga Y, Iwasaki YK, Nagashima K, Masuda M, Yamashita S, Nakamura K, Satomi K, Takatsuki S, Inoue K, Kusano K, Yamane T, Tada H, Shimizu W. Efficacy and safety of catheter ablation for paroxysmal atrial fibrillation: A comparison of first-line vs second-line therapy. Heart Rhythm. 2026 Jul;23(7):1496-1503. doi: 10.1016/j.hrthm.2025.07.030. Epub 2025 Jul 24.
PubMed 40714332
Study at a glance
From the registry record, last updated by the sponsor on 13 Nov 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Japanese Catheter Ablation Registry
- ClinicalTrials.gov ID
- NCT03729232
- Acronym / sponsor ID
- J-AB / M28-114
- Conditions
- Catheter Ablation, Cardiac Arrhythmias
- Keywords
- Catheter Ablation, Cardiac Arrhythmias, Registry, Complication, REDCap
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 400,000 participants (estimated)
- Lead sponsor
- National Cerebral and Cardiovascular Center, JapanUniversity, hospital or other
- Study start
- 1 Jul 2017 (actual)
- Primary completion
- 31 Mar 2030 (estimated)
- Study completion
- 31 Mar 2030 (estimated)
- First posted
- 2 Nov 2018 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Japanese Cather Ablation (J-AB) Registry is a voluntary nationwide registry, performed by Japanese Heart Rhythm Society, collaborated with the National Cerebral and Cardiovascular Center. The objectives of this registry are to observe and describe developments in the catheter ablation treatment of arrhythmia in Japan and to provide reliable information on the type of activity performed and the facilities available in Japanese arrhythmia units.
Detailed description
Japanese Cather Ablation (J-AB) Registry is a nationwide, multicenter, observational registry, performed by Japanese Heart Rhythm Society, collaborated with National Cerebral and Cardiovascular Center.
This study is a voluntary nationwide registry and data are collected prospectively using a Research Electronic Data Capture (REDCap) system. Detailed data collection including antiarrhythmic medication is also performed at every September. The acute success rate at discharge and the complications associated with ablation procedure will be collected in all cases. Major bleeding events are defined according to Bleeding Academic Research Consortium criteria. Based on the provided information, the annual incidence and predictive factors for outcome will be investigated by the event assessment committee.
Study design
- Observational model
- Case only
- Time perspective
- Prospective
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Inpatients
Key inclusion criteria (1 listed)
- Patients treated with catheter ablation in Japan
Key exclusion criteria (1 listed)
- Patients who refused to consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Number of patients with recurrence of targeted arrhythmia
Time frame: Through discharge from hospital, approximately up to 1 weeks
2 secondary outcomes
Number of deaths
Time frame: Through discharge from hospital, approximately up to 1 weeks
Number of patients with treatment-related complications
Time frame: 3 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Nov 2023.
- Derived from this study: PubMed 40995616Matsuda Y, Masuda M, Kanaoka K, Mano T, Inoue K, Yamashita S, Iwasaki YK, Nakamura K, Nagashima K, Miyamoto K, Satomi K, Takatsuki S, Kusano K, Yamane T, Shimizu W. Real-World Outcomes of Repeat Ablation Strategies for Atrial Fibrillation: Insights From the Japanese Catheter Ablation Registry. J Arrhythm. 2025 Sep 22;41(5):e70200. doi: 10.1002/joa3.70200. eCollection 2025 Oct.
- Derived from this study: PubMed 40861252Goto K, Miyazaki S, Tonegawa-Kuji R, Kanaoka K, Yamashita S, Sasano T, Iwanaga Y, Nakai M, Inoue K, Iwasaki YK, Nagashima K, Nakamura K, Masuda M, Miyamaoto K, Satomi K, Takatsuki S, Kusano K, Yamane T, Shimizu W. Efficacy and Safety of Second Sessions of Catheter Ablation for Idiopathic Premature Ventricular Contractions: From the Nationwide Japan Catheter Ablation Registry. J Arrhythm. 2025 Aug 25;41(4):e70181. doi: 10.1002/joa3.70181. eCollection 2025 Aug.
- Derived from this study: PubMed 40714332Oikawa J, Fukaya H, Kanaoka K, Niwano S, Miyamoto K, Iwanaga Y, Iwasaki YK, Nagashima K, Masuda M, Yamashita S, Nakamura K, Satomi K, Takatsuki S, Inoue K, Kusano K, Yamane T, Tada H, Shimizu W. Efficacy and safety of catheter ablation for paroxysmal atrial fibrillation: A comparison of first-line vs second-line therapy. Heart Rhythm. 2026 Jul;23(7):1496-1503. doi: 10.1016/j.hrthm.2025.07.030. Epub 2025 Jul 24.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Teiichi Yamane, MD, PhD principal investigator
The Jikei University School of Medicine
Kengo Kusano, MD, PhD principal investigator
National Cerebral and Cardiovascular Center, Japan
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Catheter Ablation and Cardiac Arrhythmias, run by National Cerebral and Cardiovascular Center, Japan at 1 site in Japan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 13 Nov 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Japan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Kengo Kusano, MD, PhD (+81-6-6170-1070, kusanokengo@ncvc.go.jp), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of patients with recurrence of targeted arrhythmia (time frame: Through discharge from hospital, approximately up to 1 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03729232, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Nov 2023.