Rh Negative Blood DonorNCT03741387
The Effect of Message Framing on Blood Donation-Study 2
A study testing Gain-frame questionnaire and Loss-frame questionnaire in people with Rh Negative Blood Donor, run by Guangzhou Blood Center at 1 site in China.
Trial summary
Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Rh Negative Blood Donor
- What is being tested?
- Gain-frame questionnaire and Loss-frame questionnaire
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 795 participants
- Where
- 1 siteChina
- Study dates
- 15 Mar 2019to 21 Mar 2019
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Rh negative blood donors who have donated blood between 2016 and 2018.
Who cannot join
- People who are Rh negative blood type but never have donated blood.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Saving a Life or Preventing a Death: the Effect of Message Framing on Blood Donation Among Rh Negative Donors
Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. In order to assess the effects of the gain-versus-loss framing message on blood donation among Rh negative donors, we designed two kinds of self-administered, standardized and structured questionnaires. In addition of the basic socio-demographic characteristics, one questionnaire includes the questions which survey the attitude of saving patients lives, and the other was to survey the attitude of preventing patients from death. The questionnaires were randomly sent to Rh negative blood donors.
- Conditions
- Rh Negative Blood Donor
- Being tested
- Gain-frame questionnaire, Loss-frame questionnaire
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Gain-frame questionnaireOther
Questionnaires focusing on the attitude of saving patients' lives were given to Rh negative blood donors in this group.
Loss-frame questionnaireOther
Questionnaires focusing on the attitude of preventing patients from death were given to Rh negative blood donors in this group.
| Study group | Role | What they receive |
|---|---|---|
| Gain-frame questionnaire | Experimental | Questionnaire included a picture of a patient lying in bed entitled "Will you save his life?" Donors in this group will answer the questions about attitude of saving patients' lives. Receives: Other: Gain-frame questionnaire |
| Loss-frame questionnaire | Experimental | Questionnaire included a picture of a patient lying in bed entitled "Will you prevent him from death?" Donors in this group will answer the questions about the attitude of preventing patients from death. Receives: Other: Loss-frame questionnaire |
What is being measured
The primary outcome is the main question the study is designed to answer.
The differences of attitude towards different massage framing
After participants view the picture in their questionnaires, they would answer the questions about attitude of saving patients' lives or preventing patients from death.
Measured: 1 day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Nov 2018
- Study start15 Mar 2019
- Primary completion21 Mar 2019
- Study completion21 Mar 2019
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Rh Negative Blood DonorStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 795 participants (actual)
Sponsor and investigators
- Lead sponsor
- Guangzhou Blood Center
- Sponsor type
- Other government
- Responsible party
- Principal investigator, OUYANG Jian, Guangzhou Blood Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03741387
- Sponsor's protocol ID
- Message Framing effect 2
- Status last verified
- Mar 2019
- First submitted
- 11 Nov 2018
- Last updated
- 26 Mar 2019
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Mar 2019. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Saving a Life or Preventing a Death: the Effect of Message Framing on Blood Donation Among Rh Negative Donors
- ClinicalTrials.gov ID
- NCT03741387
- Acronym / sponsor ID
- Message Framing effect 2
- Conditions
- Rh Negative Blood Donor
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 795 participants (actual)
- Lead sponsor
- Guangzhou Blood CenterOther government
- Study start
- 15 Mar 2019 (actual)
- Primary completion
- 21 Mar 2019 (actual)
- Study completion
- 21 Mar 2019 (actual)
- First posted
- 14 Nov 2018 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. In order to assess the effects of the gain-versus-loss framing message on blood donation among Rh negative donors, we designed two kinds of self-administered, standardized and structured questionnaires. In addition of the basic socio-demographic characteristics, one questionnaire includes the questions which survey the attitude of saving patients lives, and the other was to survey the attitude of preventing patients from death. The questionnaires were randomly sent to Rh negative blood donors.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Gain-frame questionnaire | Experimental | Other: Gain-frame questionnaireQuestionnaire included a picture of a patient lying in bed entitled "Will you save his life?" Donors in this group will answer the questions about attitude of saving patients' lives. |
| Loss-frame questionnaire | Experimental | Other: Loss-frame questionnaireQuestionnaire included a picture of a patient lying in bed entitled "Will you prevent him from death?" Donors in this group will answer the questions about the attitude of preventing patients from death. |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Rh negative blood donors who have donated blood between 2016 and 2018.
Key exclusion criteria (1 listed)
- People who are Rh negative blood type but never have donated blood.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Gain-frame questionnaireQuestionnaires focusing on the attitude of saving patients' lives were given to Rh negative blood donors in this group. | Other | Gain-frame questionnaire |
| Loss-frame questionnaireQuestionnaires focusing on the attitude of preventing patients from death were given to Rh negative blood donors in this group. | Other | Loss-frame questionnaire |
Primary outcome
The differences of attitude towards different massage framing
Time frame: 1 day
After participants view the picture in their questionnaires, they would answer the questions about attitude of saving patients' lives or preventing patients from death.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Mar 2019.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Gain-frame questionnaire and Loss-frame questionnaire in people with Rh Negative Blood Donor, run by Guangzhou Blood Center at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Mar 2019. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The differences of attitude towards different massage framing (time frame: 1 day). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Mar 2019; AzTrials last refreshed its copy on 6 Nov 2026.