AnesthesiaEKAT-TeleTPSNCT03747146
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
A study testing Continuous Adductor Canal Catheter (ACC) in people with Anesthesia, run by Hospital for Special Surgery, New York at 1 site in United States.
Trial summary
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block (ACB) vs. (2) PAI, IPACK and continuous adductor canal block catheter (ACC). Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Anesthesia
- What is being tested?
- Continuous Adductor Canal Catheter (ACC)
- Type of treatment
- Medical device
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 94 participants
- Where
- 1 siteUnited States
- Study dates
- 16 Nov 2018to Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon
- Planned use of regional anesthesia
- Ability to follow study protocol
- English speaking (secondary outcomes include questionnaires validated in English only)
- Lives within one hour of the hospital
- Has a smart phone
Who cannot join
- Hepatic or renal insufficiency
- Younger than 18 years old or older than 65 years ol
- Patients undergoing general anesthesia
- Allergy or intolerance to one of the study medications
- BMI >40
- Diabetes
Show all 14Show fewer
- American Society of Anesthesiologists (ASA) status III or IV
- Chronic gabapentin/pregabalin use (regular use for longer than 3 months)
- Patients with chronic pain (from a referral to chronic pain service) or a pain catastrophizing scale (PCS >30)
- Patients with severe valgus deformity or flexion contracture
- Patients unable to follow home catheter instructions and unwilling to go home with an infusing catheter
- Patients who have no home caregivers in the event that a catheter is to be sent home with the patient
- Patients with planned stay at rehab facility (to avoid medical device being tampered with at the rehab facility)
- Non-English speakers (secondary outcomes include questionnaires validated in English only)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Hospital for Special Surgery
New York, New York, 10023
David Kim, MD
About this study
Official title: Expanding the Peri-operative Surgical Home Model: ERAS TKR With a Transitional Pain Service (TeleTPS)- Continuous Adductor Canal Catheter Versus Adductor Canal Block for Total Knee Arthroplasty, a Randomized Double-blind Controlled Trial
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block (ACB) vs. (2) PAI, IPACK and continuous adductor canal block catheter (ACC).
Read the detailed description
Patients will be randomized to one of two groups: one group will receive a PAI, IPACK and single-shot adductor canal block; one group will receive PAI, IPACK and continuous adductor canal block catheter.
- Conditions
- Anesthesia
- Being tested
- Continuous Adductor Canal Catheter (ACC), Adductor Canal block with sham catheter
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Continuous Adductor Canal Catheter (ACC)Device
At the end of the case or in the PACU, a pseudo sham catheter will be affixed mid-thigh to the skin using dermabond, steri-strips, and a chg tegaderm dressing. The catheter will be connected to the disposable pump filled with sterile saline (400 cc) and the flow rate will be set to 0. The pump will be enclosed in a carrier bag provided by the company. To ensure blinding, the carrier bag will be taped to prevent the patient from accessing it.
Adductor Canal block with sham catheterDevice
Adductor canal block (ACB) will be administered. At the end of the case or in the PACU, a catheter will be inserted and affixed mid-thigh to the skin using dermabond, steri-strips, and a chg tegaderm dressing. The catheter will be connected to the disposable pump filled with sterile saline (400 cc) and the flow rate will be set to 0. The pump will be enclosed in a carrier bag provided by the company. To ensure blinding, the carrier bag will be taped to prevent the patient from accessing it.
| Study group | Role | What they receive |
|---|---|---|
| Continuous Adductor Canal Catheter (ACC) | Active comparator | Patients will receive a combined spinal epidural, PAI, IPACK, and a continuous adductor canal catheter Receives: Device: Continuous Adductor Canal Catheter (ACC) |
| Adductor Canal block with sham catheter | Sham comparator | Patients will receive a combined spinal epidural, PAI, IPACK, and an adductor canal block. The patient will also receive a sham catheter. Receives: Device: Adductor Canal block with sham catheter |
What is being measured
The primary outcome is the main question the study is designed to answer.
Opioid consumption during 24-48 hour period
Patients will be asked to report their opioid consumption during the 24-48 hour time period after spinal induction. This data will be converted to morphine milligram equivalents (mme).
Measured: Post-operative day 1-2 (24-48 hours post spinal induction)
Secondary outcomes (1)
Opioid consumption during post-anesthesia care unit (PACU) stay
Patients will be asked to report their opioid consumption during their stay in the post-anesthesia care unit. This data will be converted to morphine milligram equivalents (mme).
Measured: Day of surgery from PACU arrival until transfer to in-patient floor (up to 48 hours)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Nov 2018
- Study start16 Nov 2018
- Primary completionDec 2026 (estimated)
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for AnesthesiaStudies of the same condition, open and under way.
- More trials run by Hospital for Special Surgery, New YorkThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 94 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hospital for Special Surgery, New York
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- David Kim, MD, Principal investigator, Hospital for Special Surgery, New York
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03747146
- Sponsor's protocol ID
- 2017-1858
- Acronym
- EKAT-TeleTPS
- Status last verified
- Jan 2026
- First submitted
- 6 Nov 2018
- Last updated
- 28 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
Publications
Kim DH, Beathe J, Wetmore DS, Goytizolo E, Haskins SC, Swamidoss C, Reichel JF, Reisenger L, Rao P, Memtsoudis SG, Liu J. Single-injection adductor canal block with perineural dexamethasone versus continuous adductor canal catheter for total knee arthroplasty: a randomized controlled trial. Reg Anesth Pain Med. 2026 Jun 4:rapm-2026-107719. doi: 10.1136/rapm-2026-107719. Online ahead of print.
PubMed 42242837
Study at a glance
From the registry record, last updated by the sponsor on 28 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Expanding the Peri-operative Surgical Home Model: ERAS TKR With a Transitional Pain Service (TeleTPS)- Continuous Adductor Canal Catheter Versus Adductor Canal Block for Total Knee Arthroplasty, a Randomized Double-blind Controlled Trial
- ClinicalTrials.gov ID
- NCT03747146
- Acronym / sponsor ID
- EKAT-TeleTPS / 2017-1858
- Conditions
- Anesthesia
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 94 participants (estimated)
- Lead sponsor
- Hospital for Special Surgery, New YorkUniversity, hospital or other
- Study start
- 16 Nov 2018 (actual)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Dec 2026 (estimated)
- First posted
- 20 Nov 2018 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block (ACB) vs. (2) PAI, IPACK and continuous adductor canal block catheter (ACC).
Detailed description
Patients will be randomized to one of two groups: one group will receive a PAI, IPACK and single-shot adductor canal block; one group will receive PAI, IPACK and continuous adductor canal block catheter.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Continuous Adductor Canal Catheter (ACC) | Active comparator | Device: Continuous Adductor Canal Catheter (ACC)Patients will receive a combined spinal epidural, PAI, IPACK, and a continuous adductor canal catheter |
| Adductor Canal block with sham catheter | Sham comparator | Device: Adductor Canal block with sham catheterPatients will receive a combined spinal epidural, PAI, IPACK, and an adductor canal block. The patient will also receive a sham catheter. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon
- Planned use of regional anesthesia
- Ability to follow study protocol
- English speaking (secondary outcomes include questionnaires validated in English only)
- Lives within one hour of the hospital
Key exclusion criteria (14 listed)
- Hepatic or renal insufficiency
- Younger than 18 years old or older than 65 years ol
- Patients undergoing general anesthesia
- Allergy or intolerance to one of the study medications
- BMI >40
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Continuous Adductor Canal Catheter (ACC)At the end of the case or in the PACU, a pseudo sham catheter will be affixed mid-thigh to the skin using dermabond, steri-strips, and a chg tegaderm dressing. The catheter will be connected to the disposable pump filled with sterile saline (400 cc) and the flow rate will be set to 0. The pump will be enclosed in a carrier bag provided by the company. To ensure blinding, the carrier bag will be taped to prevent the patient from accessing it. | Device | Continuous Adductor Canal Catheter (ACC) |
| Adductor Canal block with sham catheterAdductor canal block (ACB) will be administered. At the end of the case or in the PACU, a catheter will be inserted and affixed mid-thigh to the skin using dermabond, steri-strips, and a chg tegaderm dressing. The catheter will be connected to the disposable pump filled with sterile saline (400 cc) and the flow rate will be set to 0. The pump will be enclosed in a carrier bag provided by the company. To ensure blinding, the carrier bag will be taped to prevent the patient from accessing it. | Device | Adductor Canal block with sham catheter |
Primary outcome
Opioid consumption during 24-48 hour period
Time frame: Post-operative day 1-2 (24-48 hours post spinal induction)
Patients will be asked to report their opioid consumption during the 24-48 hour time period after spinal induction. This data will be converted to morphine milligram equivalents (mme).
1 secondary outcome
Opioid consumption during post-anesthesia care unit (PACU) stay
Time frame: Day of surgery from PACU arrival until transfer to in-patient floor (up to 48 hours)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Apr 2026.
- Derived from this study: PubMed 42242837Kim DH, Beathe J, Wetmore DS, Goytizolo E, Haskins SC, Swamidoss C, Reichel JF, Reisenger L, Rao P, Memtsoudis SG, Liu J. Single-injection adductor canal block with perineural dexamethasone versus continuous adductor canal catheter for total knee arthroplasty: a randomized controlled trial. Reg Anesth Pain Med. 2026 Jun 4:rapm-2026-107719. doi: 10.1136/rapm-2026-107719. Online ahead of print.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
David Kim, MD principal investigator
Hospital for Special Surgery, New York
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Continuous Adductor Canal Catheter (ACC) in people with Anesthesia, run by Hospital for Special Surgery, New York at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 14 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact George Birch, BS (212-774-7377, birchg@hss.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Opioid consumption during 24-48 hour period (time frame: Post-operative day 1-2 (24-48 hours post spinal induction)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03747146, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Apr 2026.