Inattention and MemoryNCT03779269
Effect of Preksha Meditation on Cognitive Abilities and Pulmonary Function in Students
A study testing meditation in people with Inattention and Memory and Affect, run by Orlando Regional Medical Center at 2 sites in United States.
Trial summary
The goal of this project is to assess impact of an 8 week course of Preksha Meditation (combination of Green color and buzzing sound meditation), in a group of college students to assess potential benefits to their pulmonary function, cognitive ability (immediate recall, attention), and happiness. Read more about this study
- Who is it for?
- Ages 18 to 24 yearsHealthy volunteers can take part
- Conditions the study is for
- Inattention and Memory, Affect
- What is being tested?
- meditation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 142 participants
- Where
- 2 sitesUnited States
- Study dates
- 14 May 2017to 10 Oct 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 24 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy individuals
- No prior experience in meditation
Who cannot join
- Prior experience with meditation.
- health issues.
- Alcohol
- Smoking.
Trial locations and contacts
2 sites in 1 country.
United States2 sites
Florida International University
Miami Beach, Florida, 33199
Orlando Regional Medical Center
Orlando, Florida, 32806
About this study
Official title: Effect of Preksha Meditation (Green Color and Buzzing Meditation) on Cognitive Abilities and Pulmonary Function in Students With a Control Group
The goal of this project is to assess impact of an 8 week course of Preksha Meditation (combination of Green color and buzzing sound meditation), in a group of college students to assess potential benefits to their pulmonary function, cognitive ability (immediate recall, attention), and happiness.
Read the detailed description
Preksha Meditation Research: The goal of this project is to assess impact of an 8 week course of Preksha Meditation (combination of Green color and buzzing sound meditation), in a group of college students to assess potential benefits to their pulmonary function, cognitive ability (immediate recall, attention), and happiness. The investigators will compare the data received from prior study to analyze their performance before and after. The investigators will also compare this data with control group data, to assess potential improvements as a benchmark. Analyse the EEG data to investigate its impact on brain. Further analyze their blood cells if they show any epigenetic changes. Data analysis team will be blinded for no identifiers are available.
METHOD AND PROCEDURES:
The data analysis will be undertaken by experts and will be blinded. The data currently is only de-identified.
The data which is already collected from the research "Effect of Preksha Meditation (Green color and Buzzing Meditation) on Cognitive Abilities and Pulmonary Function in Students with a Control Group" will be analyzed. The data is related to students having practiced minimum 3 guided 25 minute sessions per week in a controlled environment. The control group did not meditate for those weeks when they enrolled in the program.
The intervention the subjects received was as follows:
Experimental group 3 days per week Sessions: 5 minutes: Relaxation and Review of Meditation Practices 10 minutes: Mahapraan Meditation 10 minutes: Green color meditation Begin in stages
- 0 - 2 Weeks: Teach technique and carry out 15 minutes meditation sessions.
- 2 - 9 Weeks: Increment meditation sessions to a length of 25 minutes. 5 minutes: Review of meditation experience and collection of information
- Conditions
- Inattention and Memory, Affect
- Being tested
- meditation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
meditationOther
meditation effect assessment using assessment tools.
| Study group | Role | What they receive |
|---|---|---|
| color meditation | Experimental | only color meditation Receives: Other: meditation |
| Sound meditation | Experimental | Only sound mediation Receives: Other: meditation |
| Color and sound combined meditation | Experimental | Combined group Receives: Other: meditation |
| Control group | No intervention | Only control group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cognitive skills assessment using Connor's CPT test
Affect, short term memory, inattention,
Measured: 8 weeks
Secondary outcomes (2)
Pulmonary function using actual lung capacity test
Spirometry
Measured: 8 weeks
Transcriptomics and epigenetics
Upregulation and transcriptional profiling using fold change
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Dec 2018
- Study start14 May 2017
- Primary completion1 Feb 2022
- Study completion10 Oct 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Inattention and MemoryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Single group
- Model description
- prospective convenience controlled study
- Masking
- None (open label)
- Enrolment
- 142 participants (actual)
Sponsor and investigators
- Lead sponsor
- Orlando Regional Medical Center
- Sponsor type
- University, hospital or other
- Collaborators
- Florida International University
- Responsible party
- Principal investigator, Devendra Mehta, Orlando Regional Medical Center
- Investigators
- Devendra Mehta, M.D., M. SC., Principal investigator, Head, Translational Research
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03779269
- Sponsor's protocol ID
- IRB-13-0045-CR03
- Status last verified
- Oct 2026
- First submitted
- 6 Dec 2018
- Last updated
- 15 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: De-identified summary data
Publications
Mehta S, Mehta V, Mehta S, Shah D, Motiwala A, Vardhan J, Mehta N, Mehta D. Multimodal behavior program for ADHD incorporating yoga and implemented by high school volunteers: a pilot study. ISRN Pediatr. 2011;2011:780745. doi: 10.5402/2011/780745. Epub 2011 Aug 11.
PubMed 22389788Pragya SU, Cordoba G, Chiu R, Mehta N, Johnson P, Mehta DI, Mehta N. Can The Cognitive Parameters Of College Students With Learning Disabilities Benefit From Using Mahapraan, A Breathing Based Preksha Meditation. Journal of College Teaching & Learning 2014; 11, 4 Epub
Abomoelak B, Kapoor N, Schreck M, Pragya SU, Pragya SC, Mehta N, Bozelli JC Jr, Shanmuganathan M, Kroezen Z, Britz-Mckibbin P, Uddin P, Veeramachaneni P, Mehta N, Prather R, Mehta A, Mehta D. Preksha Dhyana meditation modulates the serum metabolome in healthy and meditation-naive participants. Front Mol Biosci. 2026 Apr 15;13:1741802. doi: 10.3389/fmolb.2026.1741802. eCollection 2026.
PubMed 42064595Pragya SU, Pragya SC, Griswold AJ, Gu E, Mehta ND, Uddin P, Veeramachaneni P, Mehta N, Mehta D, Abomoelak B. Preksha Dhyana Meditation Effect on the DNA Methylation Signature in College Students. J Integr Complement Med. 2023 Apr;29(4):224-233. doi: 10.1089/jicm.2022.0713. Epub 2023 Feb 7.
PubMed 36749149Pragya SU, Mehta ND, Abomoelak B, Uddin P, Veeramachaneni P, Mehta N, Moore S, Jean-Francois M, Garcia S, Pragya SC, Mehta DI. Effects of Combining Meditation Techniques on Short-Term Memory, Attention, and Affect in Healthy College Students. Front Psychol. 2021 Mar 5;12:607573. doi: 10.3389/fpsyg.2021.607573. eCollection 2021.
PubMed 33746830
Study at a glance
From the registry record, last updated by the sponsor on 15 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Preksha Meditation (Green Color and Buzzing Meditation) on Cognitive Abilities and Pulmonary Function in Students With a Control Group
- ClinicalTrials.gov ID
- NCT03779269
- Acronym / sponsor ID
- IRB-13-0045-CR03
- Conditions
- Inattention and Memory, Affect
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 142 participants (actual)
- Lead sponsor
- Orlando Regional Medical CenterUniversity, hospital or other
- Collaborators
- Florida International University
- Study start
- 14 May 2017 (actual)
- Primary completion
- 1 Feb 2022 (actual)
- Study completion
- 10 Oct 2026 (actual)
- First posted
- 19 Dec 2018 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this project is to assess impact of an 8 week course of Preksha Meditation (combination of Green color and buzzing sound meditation), in a group of college students to assess potential benefits to their pulmonary function, cognitive ability (immediate recall, attention), and happiness.
Detailed description
Preksha Meditation Research: The goal of this project is to assess impact of an 8 week course of Preksha Meditation (combination of Green color and buzzing sound meditation), in a group of college students to assess potential benefits to their pulmonary function, cognitive ability (immediate recall, attention), and happiness. The investigators will compare the data received from prior study to analyze their performance before and after. The investigators will also compare this data with control group data, to assess potential improvements as a benchmark. Analyse the EEG data to investigate its impact on brain. Further analyze their blood cells if they show any epigenetic changes. Data analysis team will be blinded for no identifiers are available.
METHOD AND PROCEDURES:
The data analysis will be undertaken by experts and will be blinded. The data currently is only de-identified.
The data which is already collected from the research "Effect of Preksha Meditation (Green color and Buzzing Meditation) on Cognitive Abilities and Pulmonary Function in Students with a Control Group" will be analyzed. The data is related to students having practiced minimum 3 guided 25 minute sessions per week in a controlled environment. The control group did not meditate for those weeks when they enrolled in the program.
The intervention the subjects received was as follows:
Experimental group 3 days per week Sessions: 5 minutes: Relaxation and Review of Meditation Practices 10 minutes: Mahapraan Meditation 10 minutes: Green color meditation Begin in stages
- 0 - 2 Weeks: Teach technique and carry out 15 minutes meditation sessions.
- 2 - 9 Weeks: Increment meditation sessions to a length of 25 minutes. 5 minutes: Review of meditation experience and collection of information
Study design
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 4
- Model description
- prospective convenience controlled study
| Arm | Type | Receives |
|---|---|---|
| color meditation | Experimental | Other: meditationonly color meditation |
| Sound meditation | Experimental | Other: meditationOnly sound mediation |
| Color and sound combined meditation | Experimental | Other: meditationCombined group |
| Control group | No intervention | –Only control group |
Who may qualify
- Ages
- 18 to 24 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Healthy individuals
- No prior experience in meditation
Key exclusion criteria (4 listed)
- Prior experience with meditation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| meditationmeditation effect assessment using assessment tools. | Other | Color and sound combined meditation, Sound meditation, color meditation |
Primary outcome
Cognitive skills assessment using Connor's CPT test
Time frame: 8 weeks
Affect, short term memory, inattention,
2 secondary outcomes
Pulmonary function using actual lung capacity test
Time frame: 8 weeks
Transcriptomics and epigenetics
Time frame: 8 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Oct 2026.
- Background: PubMed 22389788Mehta S, Mehta V, Mehta S, Shah D, Motiwala A, Vardhan J, Mehta N, Mehta D. Multimodal behavior program for ADHD incorporating yoga and implemented by high school volunteers: a pilot study. ISRN Pediatr. 2011;2011:780745. doi: 10.5402/2011/780745. Epub 2011 Aug 11.
- BackgroundPragya SU, Cordoba G, Chiu R, Mehta N, Johnson P, Mehta DI, Mehta N. Can The Cognitive Parameters Of College Students With Learning Disabilities Benefit From Using Mahapraan, A Breathing Based Preksha Meditation. Journal of College Teaching & Learning 2014; 11, 4 Epub
- Derived from this study: PubMed 42064595Abomoelak B, Kapoor N, Schreck M, Pragya SU, Pragya SC, Mehta N, Bozelli JC Jr, Shanmuganathan M, Kroezen Z, Britz-Mckibbin P, Uddin P, Veeramachaneni P, Mehta N, Prather R, Mehta A, Mehta D. Preksha Dhyana meditation modulates the serum metabolome in healthy and meditation-naive participants. Front Mol Biosci. 2026 Apr 15;13:1741802. doi: 10.3389/fmolb.2026.1741802. eCollection 2026.
- Derived from this study: PubMed 36749149Pragya SU, Pragya SC, Griswold AJ, Gu E, Mehta ND, Uddin P, Veeramachaneni P, Mehta N, Mehta D, Abomoelak B. Preksha Dhyana Meditation Effect on the DNA Methylation Signature in College Students. J Integr Complement Med. 2023 Apr;29(4):224-233. doi: 10.1089/jicm.2022.0713. Epub 2023 Feb 7.
- Derived from this study: PubMed 33746830Pragya SU, Mehta ND, Abomoelak B, Uddin P, Veeramachaneni P, Mehta N, Moore S, Jean-Francois M, Garcia S, Pragya SC, Mehta DI. Effects of Combining Meditation Techniques on Short-Term Memory, Attention, and Affect in Healthy College Students. Front Psychol. 2021 Mar 5;12:607573. doi: 10.3389/fpsyg.2021.607573. eCollection 2021.
- Individual participant dataSharing planned: No. De-identified summary data
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Devendra Mehta, M.D., M. SC. principal investigator
Head, Translational Research
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing meditation in people with Inattention and Memory and Affect, run by Orlando Regional Medical Center at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cognitive skills assessment using Connor's CPT test (time frame: 8 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03779269, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Oct 2026.