Acne ScarsNCT03850925
Comparison of Picosecond Pulsed Nd:YAG Laser and Fractional Laser for the Treatment of Acne Scars
A study testing Laser therapy in people with Acne Scars, run by Dongtan Sacred Heart Hospital at 1 site in South Korea.
Trial summary
This study compares the application of a picosecond 1064-nm laser with a diffractive lens array with nonablative fractional laser for the treatment of acne scarring. Read more about this study
- Who is it for?
- Ages 19 years and olderHealthy volunteers can take part
- Conditions the study is for
- Acne Scars
- What is being tested?
- Laser therapy
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 25 participants
- Where
- 1 siteSouth Korea
- Study dates
- 1 May 2019to 22 Apr 2020
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 19 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Subjects with facial atrophic acne scars
- Subjects who observe the schedules and protocols of the clinical trial
- Subjects who give informed consent to participate in the clinical trial
Who cannot join
- Subjects who have active acne under treatment
- Subjects who had received any other treatments for acne scarring for 6 months prior to the first treatment
- Subjects who underwent other treatments including chemical, mechanical or laser resurfacing during the study period
- Subjects who have current acute illness
- Subjects who are considered inappropriate for the clinical trial under the judgement of investigators
Trial locations and contacts
1 site in 1 country.
South Korea1 site
Dongtan Sacred Heart Hospital, Hallym Universtiy College of Medicine
Hwaseong-si, Gyeonggi-do, 18450
About this study
This study compares the application of a picosecond 1064-nm laser with a diffractive lens array with nonablative fractional laser for the treatment of acne scarring.
Read the detailed description
This trial is a 17-week, prospective, randomized split-face study that compares the results between two facial sides either receiving the picosecond 1064-nm laser or nonablative fractional laser treatment for atrophic acne scar.
- Conditions
- Acne Scars
- Being tested
- Laser therapy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Laser therapyProcedure or surgery
4 consecutive sessions of laser therapy
| Study group | Role | What they receive |
|---|---|---|
| Picosecond laser | Experimental | Intervention: four consecutive sessions of 1,064-nm picosecond laser at 3-week intervals Receives: Procedure: Laser therapy |
| Fractional laser | Active comparator | Intervention: four consecutive sessions of nonablative fractional laser at 3-week intervals Receives: Procedure: Laser therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Changes in the mean of the ECCA grading scale
The ECCA (échelle d'évaluation clinique des cicatrices d'acné) grading scale: minimum score 0; maximum score 270; higher values represent a worse outcome.
Measured: Week 17
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Feb 2019
- Study start1 May 2019
- Primary completion22 Apr 2020
- Study completion22 Apr 2020
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Acne ScarsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Split-face comparison study
- Masking
- None (open label)
- Enrolment
- 25 participants (actual)
Sponsor and investigators
- Lead sponsor
- Dongtan Sacred Heart Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Gyeong-Hun Park, MD, PhD, Principal investigator, Dongtan Sacred Heart Hospital, Hallym University College of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03850925
- Sponsor's protocol ID
- 2019_02_004
- Status last verified
- Aug 2026
- First submitted
- 20 Feb 2019
- Last updated
- 26 Aug 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Picosecond Pulsed Nd:YAG Laser and Fractional Laser for the Treatment of Acne Scars
- ClinicalTrials.gov ID
- NCT03850925
- Acronym / sponsor ID
- 2019_02_004
- Conditions
- Acne Scars
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 25 participants (actual)
- Lead sponsor
- Dongtan Sacred Heart HospitalUniversity, hospital or other
- Study start
- 1 May 2019 (actual)
- Primary completion
- 22 Apr 2020 (actual)
- Study completion
- 22 Apr 2020 (actual)
- First posted
- 22 Feb 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study compares the application of a picosecond 1064-nm laser with a diffractive lens array with nonablative fractional laser for the treatment of acne scarring.
Detailed description
This trial is a 17-week, prospective, randomized split-face study that compares the results between two facial sides either receiving the picosecond 1064-nm laser or nonablative fractional laser treatment for atrophic acne scar.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Split-face comparison study
| Arm | Type | Receives |
|---|---|---|
| Picosecond laser | Experimental | Procedure: Laser therapyIntervention: four consecutive sessions of 1,064-nm picosecond laser at 3-week intervals |
| Fractional laser | Active comparator | Procedure: Laser therapyIntervention: four consecutive sessions of nonablative fractional laser at 3-week intervals |
Who may qualify
- Ages
- 19 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Subjects with facial atrophic acne scars
- Subjects who observe the schedules and protocols of the clinical trial
- Subjects who give informed consent to participate in the clinical trial
Key exclusion criteria (5 listed)
- Subjects who have active acne under treatment
- Subjects who had received any other treatments for acne scarring for 6 months prior to the first treatment
- Subjects who underwent other treatments including chemical, mechanical or laser resurfacing during the study period
- Subjects who have current acute illness
- Subjects who are considered inappropriate for the clinical trial under the judgement of investigators
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Laser therapy4 consecutive sessions of laser therapy | Procedure or surgery | Fractional laser, Picosecond laser |
Primary outcome
Changes in the mean of the ECCA grading scale
Time frame: Week 17
The ECCA (échelle d'évaluation clinique des cicatrices d'acné) grading scale: minimum score 0; maximum score 270; higher values represent a worse outcome.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Gyeong-Hun Park, MD, PhD principal investigator
Dongtan Sacred Heart Hospital, Hallym University College of Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Laser therapy in people with Acne Scars, run by Dongtan Sacred Heart Hospital at 1 site in South Korea.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Changes in the mean of the ECCA grading scale (time frame: Week 17). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Aug 2026.