Mild Cognitive ImpairmentNCT03896308
Reliability of Chinese Version of Verbal Learning Test and Selective Reminding Test
An observational study of Mild Cognitive Impairment and Test-retest Reliability, run by National Yang Ming Chiao Tung University at 1 site in Taiwan.
Trial summary
Mild cognitive impairment (MCI) is distinguished from healthy aging by cognitive difficulties that are greater than expected for one's age and education. Amnestic mild cognitive impairment (aMCI) is a major sub-type of MCI with noticeable impairments in memory. Approximately 12% of aMCI will progress to AD per year. Read more about this study
- Who is it for?
- Ages 50 to 100 years
- Conditions the study is for
- Mild Cognitive Impairment, Test-retest Reliability
- How many people
- 30 participants
- Where
- 1 siteTaiwan
- Study dates
- 25 May 2019to 19 Mar 2020
- How long will I take part?
- 2 Weeks
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 100 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Mild cognitive impairment (MCI) is distinguished from healthy aging by cognitive difficulties that are greater than expected for one's age and education. Amnestic mild cognitive impairment (aMCI) is a major sub-type of MCI with noticeable impairments in memory. Approximately 12% of aMCI will progress to AD per year. Guidelines for MCI recommended: controlling vascular risk factors and focusing on behavioral interventions.
Who may be able to join
- Age≥50 years
- Complained of memory impairment
- Chinese Version Verbal Learning Test 10-minute delays ≤ 6 words
- MMSE score≥24 and CDR score=0.5
- Activities of daily living are intact
- DSM-IV criteria for the diagnosis of dementia is not met
Who cannot join
- Any significant neurologic disease other than suspected incipient Alzheimer's disease
- Psychotic features, contraindication of exercise... which could lead to difficulty complying with the protocol
Trial locations and contacts
1 site in 1 country.
Taiwan1 site, 1 recruiting
- Recruiting
National Yang-Ming University
Taipei
Yea-Ru Yang, PhD, 886-2-28267279, yryang@ym.edu.tw
About this study
Official title: Test-retest Reliability of the Chinese Version of the Verbal Learning Test and Selective Reminding Test Among People With Mild Cognitive Impairment
Mild cognitive impairment (MCI) is distinguished from healthy aging by cognitive difficulties that are greater than expected for one's age and education. Amnestic mild cognitive impairment (aMCI) is a major sub-type of MCI with noticeable impairments in memory. Approximately 12% of aMCI will progress to AD per year. There are two test to evaluate the effects on memory, but both without Chinese version. This study is to know the test-retest reliability of the Chinese version of the Verbal learning test and Selective reminding test among people with mild cognitive impairment.
- Conditions
- Mild Cognitive Impairment, Test-retest Reliability
- Medical subject headings
- Cognitive Dysfunction
What is being measured
The primary outcome is the main question the study is designed to answer.
Chinese Version of Verbal Learning Test
Measured: Change from baseline at two week
Chinese Version of Selective Reminding Test
Measured: Change from baseline at two week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Mar 2019
- Study start25 May 2019
- Primary completion28 Feb 2020 (estimated)
- Study completion19 Mar 2020 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Mild Cognitive ImpairmentStudies of the same condition, open and under way.
- More trials run by National Yang Ming Chiao Tung UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 30 participants (estimated)
- Target duration
- 2 Weeks
Sponsor and investigators
- Lead sponsor
- National Yang Ming Chiao Tung University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Yea-Ru Yang, National Yang Ming Chiao Tung University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03896308
- Sponsor's protocol ID
- YM108036E
- Status last verified
- Aug 2019
- First submitted
- 28 Mar 2019
- Last updated
- 6 Aug 2019
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Aug 2019. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Test-retest Reliability of the Chinese Version of the Verbal Learning Test and Selective Reminding Test Among People With Mild Cognitive Impairment
- ClinicalTrials.gov ID
- NCT03896308
- Acronym / sponsor ID
- YM108036E
- Conditions
- Mild Cognitive Impairment, Test-retest Reliability
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- National Yang Ming Chiao Tung UniversityUniversity, hospital or other
- Study start
- 25 May 2019 (actual)
- Primary completion
- 28 Feb 2020 (estimated)
- Study completion
- 19 Mar 2020 (estimated)
- First posted
- 29 Mar 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Mild cognitive impairment (MCI) is distinguished from healthy aging by cognitive difficulties that are greater than expected for one's age and education. Amnestic mild cognitive impairment (aMCI) is a major sub-type of MCI with noticeable impairments in memory. Approximately 12% of aMCI will progress to AD per year. There are two test to evaluate the effects on memory, but both without Chinese version. This study is to know the test-retest reliability of the Chinese version of the Verbal learning test and Selective reminding test among people with mild cognitive impairment.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Target follow-up
- 2 Weeks
Who may qualify
- Ages
- 50 to 100 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Mild cognitive impairment (MCI) is distinguished from healthy aging by cognitive difficulties that are greater than expected for one's age and education. Amnestic mild cognitive impairment (aMCI) is a major sub-type of MCI with noticeable impairments in memory. Approximately 12% of aMCI will progress to AD per year. Guidelines for MCI recommended: controlling vascular risk factors and focusing on behavioral interventions.
Key inclusion criteria (6 listed)
- Age≥50 years
- Complained of memory impairment
- Chinese Version Verbal Learning Test 10-minute delays ≤ 6 words
- MMSE score≥24 and CDR score=0.5
- Activities of daily living are intact
Key exclusion criteria (2 listed)
- Any significant neurologic disease other than suspected incipient Alzheimer's disease
- Psychotic features, contraindication of exercise... which could lead to difficulty complying with the protocol
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Chinese Version of Verbal Learning Test
Time frame: Change from baseline at two week
Chinese Version of Selective Reminding Test
Time frame: Change from baseline at two week
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Aug 2019.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Mild Cognitive Impairment and Test-retest Reliability, run by National Yang Ming Chiao Tung University at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 6 Aug 2019. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Chinese Version of Verbal Learning Test (time frame: Change from baseline at two week). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Aug 2019.