Power Training Exercise ProtocolsPoTrRecNCT03936595
Recovery of Performance, Muscle Damage and Neuromuscular Fatigue Following Muscle Power Training
A study testing Core exercises protocol, Structural exercises protocol and Accentuated eccentric load exercises protocol in people with Power Training Exercise Protocols, run by University of Thessaly at 1 site in Greece.
Trial summary
Muscle power is one of the most important parameters in almost every athletic action, and expresses the ability of the human muscle to produce great amounts of force with the greatest possible speed. Read more about this study
- Who is it for?
- Ages 18 to 35 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Power Training Exercise Protocols
- What is being tested?
- Core exercises protocol, Structural exercises protocol and Accentuated eccentric load exercises protocol
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 10 participants
- Where
- 1 siteGreece
- Study dates
- 6 May 2019to 28 Jun 2019
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- No recent history of musculoskeletal injury
- No use of ergogenic supplements and drugs
- No use of anti-inflammatory and antioxidant supplements (> 6 months)
- No participation at intense eccentric exercise for at least 3 days before protocols
Who cannot join
- Recent history of musculoskeletal injury
- Use of ergogenic supplements and drugs
- Use of anti-inflammatory and antioxidant supplements (< 6 months)
- Participation at intense eccentric exercise for at least 3 days before protocols
Trial locations and contacts
1 site in 1 country.
Greece1 site
Laboratory of Exercise Biochemistry, Exercise Physiology,and Sports Nutrition, School of Physical Education and Sport Science, University of Thessaly
Trikala, Thessaly, 42100
About this study
Official title: Investigation on the Recovery Kinetics of Performance, Muscle Damage and Neuromuscular Fatigue Indicators, Following Different Protocols for Muscle Power Development
Muscle power is one of the most important parameters in almost every athletic action, and expresses the ability of the human muscle to produce great amounts of force with the greatest possible speed. Thus, muscle power is critical for high performance in athletic actions such as jumping, throwing, change of direction and sprinting. For enhancing their muscle power, athletes comprise several resistance training programs as part of their training. Muscle power training comprises of eccentric muscle actions, and the magnitude of these actions depend on the emphasis that is given on the concentric or eccentric action, respectively, of the muscles during the exercises. However, eccentric muscle action, especially when unaccustomed, can lead to exercise-induced muscle damage (EIMD), and deterioration of muscle performance.
Despite the fact that muscle power training comprises eccentric muscle actions, and consequently can lead to muscle injury and muscle performance reduction during the following days, the recovery kinetics after acute muscle power training have not been adequately studied. However, information regarding the recovery of the muscles after a power training protocol, is critical for the correct design of a training microcycle, and the reduction of injury risk.
The aim of the present study is to investigate the muscle injury provoked after acute muscle power training using three different power training exercise protocols. Additionally, we will examine the effect of these protocols on muscle performance and neuromuscular fatigue indices.
Read the detailed description
Muscle power is one of the most important parameters in almost every athletic action, and expresses the ability of the human muscle to produce great amounts of force with the greatest possible speed. Thus, muscle power is critical for high performance in athletic actions such as jumping, throwing, change of direction and sprinting.
For enhancing their muscle power, athletes comprise several resistance training programs as part of their training. Core exercises as long as Olympic lifting has been used in muscle power training. The loads that are applied regarding the accomplishment of the most favorable power production are varying. Training load of 0% 1RM favored power production at the countermovement squat jump, while loads of 56% 1rm and 80% 1RM, favored the power production at squat and hang clean, respectively. Additionally, In the recent years, accentuated eccentric training has been proposed as a new training method for the enhancement of muscle power. This method emphasizes the eccentric component of the muscle contraction, and there is evidence supporting the greater production of muscle force after accentuated eccentric training compared with the typical resistance exercise training method.
Taking the above into consideration, muscle power training comprises of eccentric muscle actions, and the magnitude of the eccentric component depends on the emphasis that is given on the concentric or eccentric action, respectively, of the muscles during the exercises. However, eccentric muscle action, especially when unaccustomed, can lead to exercise-induced muscle damage (EIMD). Although concentric and isometric exercise may also lead to muscle injury, the amount of damage after eccentric muscle contractions is greater. EIMD, amongst others, is accompanied by increased levels of creatine kinase (CK) into the circulation, increased delayed onset of muscle soreness (DOMS), reduction of force production, reduction of flexibility speed.
Despite the fact that muscle power training comprises eccentric muscle actions, and consequently can lead to muscle injury and muscle performance reduction during the following days, the recovery kinetics after acute muscle power training protocols have not been adequately studied. However, information regarding the recovery of the muscles after a power training protocol, is critical for the correct design of a training microcycle, and the reduction of injury risk.
The aim of the present study is to investigate the muscle injury provoked after muscle acute power training using three different power training exercise protocols. Additionally, the effect of these protocols on muscle performance and neuromuscular fatigue indices will be examined.
- Conditions
- Power Training Exercise Protocols
- Being tested
- Core exercises protocol, Structural exercises protocol, Accentuated eccentric load exercises protocol, Control condition
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Core exercises protocolOther
Participants will perform:
- Squats, 4 sets of 5 repetitions at 60% 1RM
- Deadlifts, 4 sets of 5 repetitions at 60% 1RM
- Lunges, 4 sets of 5 repetitions at 60% 1RM
- Step ups, 4 sets of 5 repetitions at 60% 1RM
Structural exercises protocolOther
Participants will perform:
- Snatch, 4 sets of 5 repetitions at 60% 1RM
- Hang clean, 4 sets of 5 repetitions at 60% 1RM
- Push jerk, 4 sets of 5 repetitions at 60% 1RM
- Split push jerk, 4 sets of 5 repetitions at 60% 1RM
Accentuated eccentric load exercises protocolOther
Participants will perform:
- Deadlifts - squat jump, 4 sets of 5 repetitions at 30% body mass (BM)
- Step down - squat jump, 4 sets of 5 repetitions at 30% BM
- Step down - lunges, 4 sets of 5 repetitions at 30% BM
- Hip thrusts, 4 sets of 5 repetitions at 30% BM
Control conditionOther
Participants will perform all the measurements that are comprised in the experimental conditions without performing any exercise protocol
| Study group | Role | What they receive |
|---|---|---|
| Core exercises protocol | Experimental | Participants will perform 4 core exercises Receives: Other: Core exercises protocol |
| Structural exercises protocol | Experimental | Participants will perform 4 structural (Olympic lifting) exercises Receives: Other: Structural exercises protocol |
| Accentuated eccentric load exercises protocol | Experimental | Participants will perform 4 exercises with eccentric loading Receives: Other: Accentuated eccentric load exercises protocol |
| Control condition | Other | Participants will perform all the measurements that are comprised in the experimental conditions without performing any exercise protocol Receives: Other: Control condition |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change on delayed onset of muscle soreness (DOMS), in the knee flexors (KF) and extensors (KE) of both limbs
Participants will perform three repetitions of a full squat movement, and rate their soreness level in knee flexors and extensors on a visual analog scale from 1 to 10 (VAS, with "no pain" at one end and "extremely sore" at the other), using palpation of the belly and the distal region of relaxed knee extensors and flexors.
Measured: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Change on countermovement jump (CMJ) height
CMJ height will be measured in 3 maximal efforts (the best jump will be recorded) on an Ergojump contact platform
Measured: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Change on isometric peak torque of the knee extensors (KE)
Isometric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Measured: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Change on isometric peak torque of the knee flexors (KF)
Isometric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Measured: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Change on concentric isokinetic peak torque of the knee extensors (KE)
Concentric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Measured: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Change on concentric isokinetic peak torque of the knee flexors (KF)
Concentric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Measured: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Change one eccentric isokinetic peak torque of the knee extensors (KE)
Eccentric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Measured: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Change on eccentric isokinetic peak torque of the knee flexors (KF)
Eccentric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Measured: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Change on the concentration of plasma CK activity
Plasma CK activity will be measured with a biochemical analyzer
Measured: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Change on the concentration of blood lactate
Lactate will be measured with a portable lactate analyzer using capillary blood
Measured: Prior to, and immediately after the end of the experimental protocol
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 May 2019
- Study start6 May 2019
- Primary completion16 Jun 2019
- Study completion28 Jun 2019
Why it stopped: There was a high drop-out rate and we were unable to recruit new subjects.
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (6)Papers the sponsor has linked to this study.
- Other trials for Power Training Exercise ProtocolsStudies of the same condition, open and under way.
- More trials run by University of ThessalyThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Model description
- Each participant will perform in a random order all four different experimental conditions
- Masking
- None (open label)
- Enrolment
- 10 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Thessaly
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ioannis G. Fatouros, University of Thessaly
- Investigators
- Ioannis G Fatouros, PhD, Principal investigator, University of Thessaly
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03936595
- Sponsor's protocol ID
- Power Training-Recovery UTH
- Acronym
- PoTrRec
- Status last verified
- Dec 2020
- First submitted
- 30 Apr 2019
- Last updated
- 5 Jan 2021
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Cormie P, McCaulley GO, Triplett NT, McBride JM. Optimal loading for maximal power output during lower-body resistance exercises. Med Sci Sports Exerc. 2007 Feb;39(2):340-9. doi: 10.1249/01.mss.0000246993.71599.bf.
PubMed 17277599Baird MF, Graham SM, Baker JS, Bickerstaff GF. Creatine-kinase- and exercise-related muscle damage implications for muscle performance and recovery. J Nutr Metab. 2012;2012:960363. doi: 10.1155/2012/960363. Epub 2012 Jan 11.
PubMed 22288008Deli CK, Fatouros IG, Paschalis V, Georgakouli K, Zalavras A, Avloniti A, Koutedakis Y, Jamurtas AZ. A Comparison of Exercise-Induced Muscle Damage Following Maximal Eccentric Contractions in Men and Boys. Pediatr Exerc Sci. 2017 Aug;29(3):316-325. doi: 10.1123/pes.2016-0185. Epub 2017 Feb 6.
PubMed 28165870Jamurtas AZ, Theocharis V, Tofas T, Tsiokanos A, Yfanti C, Paschalis V, Koutedakis Y, Nosaka K. Comparison between leg and arm eccentric exercises of the same relative intensity on indices of muscle damage. Eur J Appl Physiol. 2005 Oct;95(2-3):179-85. doi: 10.1007/s00421-005-1345-0. Epub 2005 Jul 9.
PubMed 16007451Kyrolainen H, Avela J, McBride JM, Koskinen S, Andersen JL, Sipila S, Takala TE, Komi PV. Effects of power training on muscle structure and neuromuscular performance. Scand J Med Sci Sports. 2005 Feb;15(1):58-64. doi: 10.1111/j.1600-0838.2004.00390.x.
PubMed 15679573Walker S, Blazevich AJ, Haff GG, Tufano JJ, Newton RU, Hakkinen K. Greater Strength Gains after Training with Accentuated Eccentric than Traditional Isoinertial Loads in Already Strength-Trained Men. Front Physiol. 2016 Apr 27;7:149. doi: 10.3389/fphys.2016.00149. eCollection 2016.
PubMed 27199764
Study at a glance
From the registry record, last updated by the sponsor on 5 Jan 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation on the Recovery Kinetics of Performance, Muscle Damage and Neuromuscular Fatigue Indicators, Following Different Protocols for Muscle Power Development
- ClinicalTrials.gov ID
- NCT03936595
- Acronym / sponsor ID
- PoTrRec / Power Training-Recovery UTH
- Conditions
- Power Training Exercise Protocols
- Study type
- Interventional
- Recruitment status
- TerminatedReason stopped: There was a high drop-out rate and we were unable to recruit new subjects.
- Enrolment
- 10 participants (actual)
- Lead sponsor
- University of ThessalyUniversity, hospital or other
- Study start
- 6 May 2019 (actual)
- Primary completion
- 16 Jun 2019 (actual)
- Study completion
- 28 Jun 2019 (actual)
- First posted
- 3 May 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Muscle power is one of the most important parameters in almost every athletic action, and expresses the ability of the human muscle to produce great amounts of force with the greatest possible speed. Thus, muscle power is critical for high performance in athletic actions such as jumping, throwing, change of direction and sprinting. For enhancing their muscle power, athletes comprise several resistance training programs as part of their training. Muscle power training comprises of eccentric muscle actions, and the magnitude of these actions depend on the emphasis that is given on the concentric or eccentric action, respectively, of the muscles during the exercises. However, eccentric muscle action, especially when unaccustomed, can lead to exercise-induced muscle damage (EIMD), and deterioration of muscle performance.
Despite the fact that muscle power training comprises eccentric muscle actions, and consequently can lead to muscle injury and muscle performance reduction during the following days, the recovery kinetics after acute muscle power training have not been adequately studied. However, information regarding the recovery of the muscles after a power training protocol, is critical for the correct design of a training microcycle, and the reduction of injury risk.
The aim of the present study is to investigate the muscle injury provoked after acute muscle power training using three different power training exercise protocols. Additionally, we will examine the effect of these protocols on muscle performance and neuromuscular fatigue indices.
Detailed description
Muscle power is one of the most important parameters in almost every athletic action, and expresses the ability of the human muscle to produce great amounts of force with the greatest possible speed. Thus, muscle power is critical for high performance in athletic actions such as jumping, throwing, change of direction and sprinting.
For enhancing their muscle power, athletes comprise several resistance training programs as part of their training. Core exercises as long as Olympic lifting has been used in muscle power training. The loads that are applied regarding the accomplishment of the most favorable power production are varying. Training load of 0% 1RM favored power production at the countermovement squat jump, while loads of 56% 1rm and 80% 1RM, favored the power production at squat and hang clean, respectively. Additionally, In the recent years, accentuated eccentric training has been proposed as a new training method for the enhancement of muscle power. This method emphasizes the eccentric component of the muscle contraction, and there is evidence supporting the greater production of muscle force after accentuated eccentric training compared with the typical resistance exercise training method.
Taking the above into consideration, muscle power training comprises of eccentric muscle actions, and the magnitude of the eccentric component depends on the emphasis that is given on the concentric or eccentric action, respectively, of the muscles during the exercises. However, eccentric muscle action, especially when unaccustomed, can lead to exercise-induced muscle damage (EIMD). Although concentric and isometric exercise may also lead to muscle injury, the amount of damage after eccentric muscle contractions is greater. EIMD, amongst others, is accompanied by increased levels of creatine kinase (CK) into the circulation, increased delayed onset of muscle soreness (DOMS), reduction of force production, reduction of flexibility speed.
Despite the fact that muscle power training comprises eccentric muscle actions, and consequently can lead to muscle injury and muscle performance reduction during the following days, the recovery kinetics after acute muscle power training protocols have not been adequately studied. However, information regarding the recovery of the muscles after a power training protocol, is critical for the correct design of a training microcycle, and the reduction of injury risk.
The aim of the present study is to investigate the muscle injury provoked after muscle acute power training using three different power training exercise protocols. Additionally, the effect of these protocols on muscle performance and neuromuscular fatigue indices will be examined.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 4
- Model description
- Each participant will perform in a random order all four different experimental conditions
| Arm | Type | Receives |
|---|---|---|
| Core exercises protocol | Experimental | Other: Core exercises protocolParticipants will perform 4 core exercises |
| Structural exercises protocol | Experimental | Other: Structural exercises protocolParticipants will perform 4 structural (Olympic lifting) exercises |
| Accentuated eccentric load exercises protocol | Experimental | Other: Accentuated eccentric load exercises protocolParticipants will perform 4 exercises with eccentric loading |
| Control condition | Other | Other: Control conditionParticipants will perform all the measurements that are comprised in the experimental conditions without performing any exercise protocol |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- No recent history of musculoskeletal injury
- No use of ergogenic supplements and drugs
- No use of anti-inflammatory and antioxidant supplements (> 6 months)
- No participation at intense eccentric exercise for at least 3 days before protocols
Key exclusion criteria (4 listed)
- Recent history of musculoskeletal injury
- Use of ergogenic supplements and drugs
- Use of anti-inflammatory and antioxidant supplements (< 6 months)
- Participation at intense eccentric exercise for at least 3 days before protocols
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Core exercises protocolParticipants will perform: 1. Squats, 4 sets of 5 repetitions at 60% 1RM 2. Deadlifts, 4 sets of 5 repetitions at 60% 1RM 3. Lunges, 4 sets of 5 repetitions at 60% 1RM 4. Step ups, 4 sets of 5 repetitions at 60% 1RM | Other | Core exercises protocol |
| Structural exercises protocolParticipants will perform: 1. Snatch, 4 sets of 5 repetitions at 60% 1RM 2. Hang clean, 4 sets of 5 repetitions at 60% 1RM 3. Push jerk, 4 sets of 5 repetitions at 60% 1RM 4. Split push jerk, 4 sets of 5 repetitions at 60% 1RM | Other | Structural exercises protocol |
| Accentuated eccentric load exercises protocolParticipants will perform: 1. Deadlifts - squat jump, 4 sets of 5 repetitions at 30% body mass (BM) 2. Step down - squat jump, 4 sets of 5 repetitions at 30% BM 3. Step down - lunges, 4 sets of 5 repetitions at 30% BM 4. Hip thrusts, 4 sets of 5 repetitions at 30% BM | Other | Accentuated eccentric load exercises protocol |
| Control conditionParticipants will perform all the measurements that are comprised in the experimental conditions without performing any exercise protocol | Other | Control condition |
Primary outcome
Change on delayed onset of muscle soreness (DOMS), in the knee flexors (KF) and extensors (KE) of both limbs
Time frame: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Participants will perform three repetitions of a full squat movement, and rate their soreness level in knee flexors and extensors on a visual analog scale from 1 to 10 (VAS, with "no pain" at one end and "extremely sore" at the other), using palpation of the belly and the distal region of relaxed knee extensors and flexors.
Change on countermovement jump (CMJ) height
Time frame: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
CMJ height will be measured in 3 maximal efforts (the best jump will be recorded) on an Ergojump contact platform
Change on isometric peak torque of the knee extensors (KE)
Time frame: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Isometric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Change on isometric peak torque of the knee flexors (KF)
Time frame: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Isometric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Change on concentric isokinetic peak torque of the knee extensors (KE)
Time frame: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Concentric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Change on concentric isokinetic peak torque of the knee flexors (KF)
Time frame: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Concentric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Change one eccentric isokinetic peak torque of the knee extensors (KE)
Time frame: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Eccentric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec
Change on eccentric isokinetic peak torque of the knee flexors (KF)
Time frame: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Eccentric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec
Change on the concentration of plasma CK activity
Time frame: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol
Plasma CK activity will be measured with a biochemical analyzer
Change on the concentration of blood lactate
Time frame: Prior to, and immediately after the end of the experimental protocol
Lactate will be measured with a portable lactate analyzer using capillary blood
Results and safety
The study was stopped early (reason given: There was a high drop-out rate and we were unable to recruit new subjects.). Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Jan 2021.
- Background: PubMed 17277599Cormie P, McCaulley GO, Triplett NT, McBride JM. Optimal loading for maximal power output during lower-body resistance exercises. Med Sci Sports Exerc. 2007 Feb;39(2):340-9. doi: 10.1249/01.mss.0000246993.71599.bf.
- Background: PubMed 22288008Baird MF, Graham SM, Baker JS, Bickerstaff GF. Creatine-kinase- and exercise-related muscle damage implications for muscle performance and recovery. J Nutr Metab. 2012;2012:960363. doi: 10.1155/2012/960363. Epub 2012 Jan 11.
- Background: PubMed 28165870Deli CK, Fatouros IG, Paschalis V, Georgakouli K, Zalavras A, Avloniti A, Koutedakis Y, Jamurtas AZ. A Comparison of Exercise-Induced Muscle Damage Following Maximal Eccentric Contractions in Men and Boys. Pediatr Exerc Sci. 2017 Aug;29(3):316-325. doi: 10.1123/pes.2016-0185. Epub 2017 Feb 6.
- Background: PubMed 16007451Jamurtas AZ, Theocharis V, Tofas T, Tsiokanos A, Yfanti C, Paschalis V, Koutedakis Y, Nosaka K. Comparison between leg and arm eccentric exercises of the same relative intensity on indices of muscle damage. Eur J Appl Physiol. 2005 Oct;95(2-3):179-85. doi: 10.1007/s00421-005-1345-0. Epub 2005 Jul 9.
- Background: PubMed 15679573Kyrolainen H, Avela J, McBride JM, Koskinen S, Andersen JL, Sipila S, Takala TE, Komi PV. Effects of power training on muscle structure and neuromuscular performance. Scand J Med Sci Sports. 2005 Feb;15(1):58-64. doi: 10.1111/j.1600-0838.2004.00390.x.
- Background: PubMed 27199764Walker S, Blazevich AJ, Haff GG, Tufano JJ, Newton RU, Hakkinen K. Greater Strength Gains after Training with Accentuated Eccentric than Traditional Isoinertial Loads in Already Strength-Trained Men. Front Physiol. 2016 Apr 27;7:149. doi: 10.3389/fphys.2016.00149. eCollection 2016.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ioannis G Fatouros, PhD principal investigator
University of Thessaly
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Core exercises protocol, Structural exercises protocol and Accentuated eccentric load exercises protocol in people with Power Training Exercise Protocols, run by University of Thessaly at 1 site in Greece.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 5 Jan 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Greece. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was stopped early (reason given: There was a high drop-out rate and we were unable to recruit new subjects.). Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change on delayed onset of muscle soreness (DOMS), in the knee flexors (KF) and extensors (KE) of both limbs (time frame: Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol). The study lists 10 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03936595, which also lists 6 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Jan 2021.