ExerciseNCT03981250
Effect of One Minute of Resistance Exercise Per Day on Muscular Strength (The ONE Study)
A study testing 12-week home-based resistance exercise programme in people with Exercise, run by University of Glasgow at 1 site in United Kingdom.
Trial summary
This study will evaluate the effect of one minute of resistance exercise per day on muscular strength in adults. Half of the participants will undergo a 12-week home-based resistance exercise programme, while the other half will continue their usual lifestyle behaviour. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Exercise
- What is being tested?
- 12-week home-based resistance exercise programme
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 56 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- 20 Jun 2019to 31 Dec 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Aged 18-65 years
Who cannot join
- Diabetes
- Uncontrolled hypertension (blood pressure > 150/90 on medication).
- History of cardiovascular disease
- Undertaking more than 150 minutes of moderate intensity or 75 minutes of vigorous physical activity or undertaking any resistance exercise.
- Other significant illness that would prevent the participant to undertake physical activity.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The ONE Study: Effect of One Minute of Resistance Exercise Per Day on Muscular Strength
This study will evaluate the effect of one minute of resistance exercise per day on muscular strength in adults. Half of the participants will undergo a 12-week home-based resistance exercise programme, while the other half will continue their usual lifestyle behaviour.
Read the detailed description
A resistance training programme can lead to a variety of health benefits including increases in muscle size and strength. Other potential health benefits of resistance training include reduction of body fat, increased metabolic rate, improve insulin sensitivity, blood glucose tolerance and blood lipid profiles. Meta-analyses indicate that while performing resistance exercise two or more times per week of resistance exercise per muscle group appears to be optimal to maximise strength gains, a single set of resistance exercise per muscle group per week, if performed to failure is sufficient to induce substantial strength changes.
The current physical activity guidelines recommend undertaking muscle strengthening activities involving major muscle groups two days a week or more, as well as undertaking at least 150 minutes per week of moderate intensity physical activity (or 75 minutes per week of vigorous intensity physical activity). However, only small portion of the population achieves the muscle strengthening aspect of the guidelines. As lack of time is often cited as a reason not to engage in physical activity, this study is seeking to investigate a low time-commitment approach to resistance exercise which could increase muscular strength. To address this, the present study will to split a typical single session of resistance exercise involving several exercises across different muscle groups into separate 1-minute micro-sessions where a different muscle group is exercised on each day of the week. The aim is to determine the effects of a one-minute-per-day home-based resistance exercise training on muscular strength.
The study is a randomized control trial in which the control group will continue their lifestyle behaviour and will be asked not to increase their physical activity levels and the exercise group will perform a 12-week home-based resistance exercise programme, involving doing one minute of resistance exercise per day on six days of the week, with a different exercise performed on each day. All participants will be measured at baseline, 4 weeks, 8 weeks and 12 weeks.
- Conditions
- Exercise
- Being tested
- 12-week home-based resistance exercise programme
- Keywords
- Resistance training, Strength Training, Muscle Strength, voluntary failure
- Medical subject headings
- Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
12-week home-based resistance exercise programmeBehavioural
Participants will perform 6 exercises (press-ups, squats, squat jumps, plank, upright row and seated row) for one minute, aiming for the maximum number of repetitions. Participants will perform one exercise per day, for 6 days a week, for 12 weeks.
| Study group | Role | What they receive |
|---|---|---|
| Control Group | No intervention | The control group will be asked to keep their lifestyle behaviour and not increase their physical activity levels during the study period. |
| Exercise Group | Experimental | The exercise group will engage in a home-based resistance exercise intervention for 12 weeks. They will perform 6 exercises, one each day for one minute, for 6 days a week. Receives: Behavioral: 12-week home-based resistance exercise programme |
What is being measured
The primary outcome is the main question the study is designed to answer.
Muscle strength
Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).
Measured: Change between baseline and 4 weeks
Muscle strength
Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).
Measured: Change between baseline and 8 weeks
Muscle strength
Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).
Measured: Change between baseline and 12 weeks
Secondary outcomes (16)
Muscle endurance
Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.
Measured: Change between baseline and 4 weeks
Muscle endurance
Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.
Measured: Change between baseline and 8 weeks
Muscle endurance
Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.
Measured: Change between baseline and 12 weeks
Weight
Change in weight (kg).
Measured: Change between baseline and 4 weeks
Weight
Change in weight (kg).
Measured: Change between baseline and 8 weeks
Weight
Change in weight (kg).
Measured: Change between baseline and 12 weeks
Waist
Change in waist circumference (cm).
Measured: Change between baseline and 4 weeks
Waist
Change in waist circumference (cm).
Measured: Change between baseline and 8 weeks
Waist
Change in waist circumference (cm).
Measured: Change between baseline and 12 weeks
Body composition
Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).
Measured: Change between baseline and 4 weeks
Body composition
Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).
Measured: Change between baseline and 8 weeks
Body composition
Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).
Measured: Change between baseline and 12 weeks
Muscle thickness
Change in muscle thickness of vastus lateralis (mm) measured with ultrasound.
Measured: Change between baseline and 12 weeks
Grip strength
Change in grip strength (kg) measured using a hand grip dynamometer
Measured: Change between baseline and 4 weeks
Grip strength
Change in grip strength (kg) measured using a hand grip dynamometer
Measured: Change between baseline and 8 weeks
Grip strength
Change in grip strength (kg) measured using a hand grip dynamometer
Measured: Change between baseline and 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Jun 2019
- Study start20 Jun 2019
- Primary completion28 Oct 2021 (estimated)
- Study completion31 Dec 2021 (estimated)
Why it stopped: Covid-19
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ExerciseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Randomized controlled trial.
- Masking
- None (open label)
- Enrolment
- 56 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Glasgow
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Professor Jason Gill, University of Glasgow
- Investigators
- Jason Gill, PhD, Principal investigator, University of Glasgow
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03981250
- Sponsor's protocol ID
- 200180137
- Status last verified
- Sep 2020
- First submitted
- 6 Jun 2019
- Last updated
- 30 Sep 2020
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Sep 2020. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The ONE Study: Effect of One Minute of Resistance Exercise Per Day on Muscular Strength
- ClinicalTrials.gov ID
- NCT03981250
- Acronym / sponsor ID
- 200180137
- Conditions
- Exercise
- Keywords
- Resistance training, Strength Training, Muscle Strength, voluntary failure
- Study type
- Interventional
- Recruitment status
- SuspendedReason stopped: Covid-19
- Enrolment
- 56 participants (estimated)
- Lead sponsor
- University of GlasgowUniversity, hospital or other
- Study start
- 20 Jun 2019 (actual)
- Primary completion
- 28 Oct 2021 (estimated)
- Study completion
- 31 Dec 2021 (estimated)
- First posted
- 10 Jun 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will evaluate the effect of one minute of resistance exercise per day on muscular strength in adults. Half of the participants will undergo a 12-week home-based resistance exercise programme, while the other half will continue their usual lifestyle behaviour.
Detailed description
A resistance training programme can lead to a variety of health benefits including increases in muscle size and strength. Other potential health benefits of resistance training include reduction of body fat, increased metabolic rate, improve insulin sensitivity, blood glucose tolerance and blood lipid profiles. Meta-analyses indicate that while performing resistance exercise two or more times per week of resistance exercise per muscle group appears to be optimal to maximise strength gains, a single set of resistance exercise per muscle group per week, if performed to failure is sufficient to induce substantial strength changes.
The current physical activity guidelines recommend undertaking muscle strengthening activities involving major muscle groups two days a week or more, as well as undertaking at least 150 minutes per week of moderate intensity physical activity (or 75 minutes per week of vigorous intensity physical activity). However, only small portion of the population achieves the muscle strengthening aspect of the guidelines. As lack of time is often cited as a reason not to engage in physical activity, this study is seeking to investigate a low time-commitment approach to resistance exercise which could increase muscular strength. To address this, the present study will to split a typical single session of resistance exercise involving several exercises across different muscle groups into separate 1-minute micro-sessions where a different muscle group is exercised on each day of the week. The aim is to determine the effects of a one-minute-per-day home-based resistance exercise training on muscular strength.
The study is a randomized control trial in which the control group will continue their lifestyle behaviour and will be asked not to increase their physical activity levels and the exercise group will perform a 12-week home-based resistance exercise programme, involving doing one minute of resistance exercise per day on six days of the week, with a different exercise performed on each day. All participants will be measured at baseline, 4 weeks, 8 weeks and 12 weeks.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Randomized controlled trial.
| Arm | Type | Receives |
|---|---|---|
| Control Group | No intervention | –The control group will be asked to keep their lifestyle behaviour and not increase their physical activity levels during the study period. |
| Exercise Group | Experimental | Behavioral: 12-week home-based resistance exercise programmeThe exercise group will engage in a home-based resistance exercise intervention for 12 weeks. They will perform 6 exercises, one each day for one minute, for 6 days a week. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Aged 18-65 years
Key exclusion criteria (5 listed)
- Diabetes
- Uncontrolled hypertension (blood pressure > 150/90 on medication).
- History of cardiovascular disease
- Undertaking more than 150 minutes of moderate intensity or 75 minutes of vigorous physical activity or undertaking any resistance exercise.
- Other significant illness that would prevent the participant to undertake physical activity.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| 12-week home-based resistance exercise programmeParticipants will perform 6 exercises (press-ups, squats, squat jumps, plank, upright row and seated row) for one minute, aiming for the maximum number of repetitions. Participants will perform one exercise per day, for 6 days a week, for 12 weeks. | Behavioural | Exercise Group |
Primary outcome
Muscle strength
Time frame: Change between baseline and 4 weeks
Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).
Muscle strength
Time frame: Change between baseline and 8 weeks
Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).
Muscle strength
Time frame: Change between baseline and 12 weeks
Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).
16 secondary outcomes
Muscle endurance
Time frame: Change between baseline and 4 weeks
Muscle endurance
Time frame: Change between baseline and 8 weeks
Muscle endurance
Time frame: Change between baseline and 12 weeks
Weight
Time frame: Change between baseline and 4 weeks
Weight
Time frame: Change between baseline and 8 weeks
Weight
Time frame: Change between baseline and 12 weeks
Waist
Time frame: Change between baseline and 4 weeks
Waist
Time frame: Change between baseline and 8 weeks
Waist
Time frame: Change between baseline and 12 weeks
Body composition
Time frame: Change between baseline and 4 weeks
Body composition
Time frame: Change between baseline and 8 weeks
Body composition
Time frame: Change between baseline and 12 weeks
Muscle thickness
Time frame: Change between baseline and 12 weeks
Grip strength
Time frame: Change between baseline and 4 weeks
Grip strength
Time frame: Change between baseline and 8 weeks
Grip strength
Time frame: Change between baseline and 12 weeks
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Sep 2020.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Jason Gill, PhD principal investigator
University of Glasgow
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing 12-week home-based resistance exercise programme in people with Exercise, run by University of Glasgow at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: paused, as of the sponsor's last update on 30 Sep 2020. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Muscle strength (time frame: Change between baseline and 4 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Sep 2020.