Cerebellar AtaxiaNCT04010214
A Registered Cohort Study on Cerebellar Ataxia in the Organization in South-East China for Cerebellar Ataxia Research (OSCCAR)
An observational study of Cerebellar Ataxia, run by Ning Wang, MD., PhD. at 1 site in China.
Trial summary
Cerebellar ataxia is a form of ataxia originating in the cerebellum. Cerebellar ataxia can occur as a result of many diseases and may present with symptoms of an inability to coordinate balance, gait, extremity and eye movements. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Cerebellar Ataxia
- How many people
- 1,500 participants
- Where
- 1 siteChina
- Study dates
- 1 Jul 2019to Dec 2059
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Patients with cerebellar ataxia who are diagnosed by tow neurologists in the Organization in South-East China for Cerebellar Ataxia Research (OSCCAR) from the First Affiliated Hospital of Fujian Medical University.
Who may be able to join
- Patients with cerebellar ataxia based on the diagnoses of tow neurologists
- Relatives of patients with cerebellar ataxia
- Unrelated healthy controls
- Participants or legal guardian(s) willing and able to complete the informed consent process
Who cannot join
- Participants are unable to comply with trial procedures and visit schedule
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
Department of Neurology ,First Affiliated Hospital Fujian Medical University
Fuzhou, Fujian, 350005
About this study
Official title: A Registered Cohort Study on Cerebellar Ataxia
Cerebellar ataxia is a form of ataxia originating in the cerebellum. Cerebellar ataxia can occur as a result of many diseases and may present with symptoms of an inability to coordinate balance, gait, extremity and eye movements. To understand the clinical and genetic characteristics of cerebellar ataxia, we establish a registered cohort to follow up Chinese patients with cerebellar ataxia.
- Conditions
- Cerebellar Ataxia
- Being tested
- No intervention
- Medical subject headings
- Cerebellar Ataxia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No interventionOther
No intervention
What is being measured
The primary outcome is the main question the study is designed to answer.
The incidence of hereditary cerebellar ataxia
Look for the causative gene in the patient with cerebellar ataxia
Measured: Up to 20years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jul 2019
- Study start1 Jul 2019
- Primary completionDec 2039 (estimated)
- Study completionDec 2059 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Cerebellar AtaxiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 1,500 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ning Wang, MD., PhD.
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Ning Wang, MD., PhD., First Affiliated Hospital of Fujian Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04010214
- Sponsor's protocol ID
- MRCTA,ECFAH of FMU[2019]195
- Status last verified
- Jul 2023
- First submitted
- 4 Jul 2019
- Last updated
- 12 Jul 2023
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Li C, Ye ZX, Chen XY, Qiu LL, Chen ZL, Qiu YS, Lin W, Yuan RY, Yu XT, Huang CY, Chen XY, Lin MT, Hu JP, Chen WJ, Wang N, Yao SB, Gan SR, Fu Y. Stage-Specific Patterns of Imaging and Non-Motor Biomarkers in Spinocerebellar Ataxia Type 3. Ann Clin Transl Neurol. 2026 Oct 13:10.1002/acn3.70555. doi: 10.1002/acn3.70555. Online ahead of print.
PubMed 42867110
Study at a glance
From the registry record, last updated by the sponsor on 12 Jul 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Registered Cohort Study on Cerebellar Ataxia
- ClinicalTrials.gov ID
- NCT04010214
- Acronym / sponsor ID
- MRCTA,ECFAH of FMU[2019]195
- Conditions
- Cerebellar Ataxia
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 1,500 participants (estimated)
- Lead sponsor
- Ning Wang, MD., PhD.University, hospital or other
- Study start
- 1 Jul 2019 (actual)
- Primary completion
- Dec 2039 (estimated)
- Study completion
- Dec 2059 (estimated)
- First posted
- 8 Jul 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Cerebellar ataxia is a form of ataxia originating in the cerebellum. Cerebellar ataxia can occur as a result of many diseases and may present with symptoms of an inability to coordinate balance, gait, extremity and eye movements. To understand the clinical and genetic characteristics of cerebellar ataxia, we establish a registered cohort to follow up Chinese patients with cerebellar ataxia.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Patients with cerebellar ataxia who are diagnosed by tow neurologists in the Organization in South-East China for Cerebellar Ataxia Research (OSCCAR) from the First Affiliated Hospital of Fujian Medical University.
Key inclusion criteria (4 listed)
- Patients with cerebellar ataxia based on the diagnoses of tow neurologists
- Relatives of patients with cerebellar ataxia
- Unrelated healthy controls
- Participants or legal guardian(s) willing and able to complete the informed consent process
Key exclusion criteria (1 listed)
- Participants are unable to comply with trial procedures and visit schedule
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No interventionNo intervention | Other | – |
Primary outcome
The incidence of hereditary cerebellar ataxia
Time frame: Up to 20years
Look for the causative gene in the patient with cerebellar ataxia
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Jul 2023.
- Derived from this study: PubMed 42867110Li C, Ye ZX, Chen XY, Qiu LL, Chen ZL, Qiu YS, Lin W, Yuan RY, Yu XT, Huang CY, Chen XY, Lin MT, Hu JP, Chen WJ, Wang N, Yao SB, Gan SR, Fu Y. Stage-Specific Patterns of Imaging and Non-Motor Biomarkers in Spinocerebellar Ataxia Type 3. Ann Clin Transl Neurol. 2026 Oct 13:10.1002/acn3.70555. doi: 10.1002/acn3.70555. Online ahead of print.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cerebellar Ataxia, run by Ning Wang, MD., PhD. at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 12 Jul 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Shi-Rui Gan, MD.Phd (+8613850172725, ganshirui@fjmu.edu.cn), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The incidence of hereditary cerebellar ataxia (time frame: Up to 20years). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04010214, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Jul 2023.