Hamstring TightnessNCT04024839
Comparison of Active Isolated Stretch and Post Isometric Relaxation for Hamstring Flexibility.
A study testing Active Isolated Stretch and Post Isometric Relaxation in people with Hamstring Tightness, run by Riphah International University at 1 site in Pakistan.
Trial summary
This study was intended to compare the immediate, short term and long term effects of active isolated stretch versus post isometric relaxation on hamstring flexibility in young healthy adults.35 students were assigned randomly into two groups with 17 and 18 in each group. Read more about this study
- Who is it for?
- Ages 18 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Hamstring Tightness
- What is being tested?
- Active Isolated Stretch and Post Isometric Relaxation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 35 participants
- Where
- 1 sitePakistan
- Study dates
- 2 Jan 2018to 30 Jul 2018
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Tight hamstring (Inability to achieve greater than 160° of knee extension with hip at 90° of flexion).
Who cannot join
- Having hamstring injury in past 6 months
- Having any neurological or orthopedic disorder effecting low back and lower limbs.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of Active Isolated Stretch and Post Isometric Relaxation for Hamstring Flexibility in Young Health Adults.
This study was intended to compare the immediate, short term and long term effects of active isolated stretch versus post isometric relaxation on hamstring flexibility in young healthy adults.35 students were assigned randomly into two groups with 17 and 18 in each group. Group A was given post isometric relaxation while Group B was Active isolated stretch. 22.2 year male and female students with tight hamstring were included while any neurological and orthopedic disorder were excluded. Active Isolated Stretch and Post Isometric Relaxation at baseline, after first and final exercise session were calculated immediate and short term effects while long term effects were calculated after two weeks of final session.
Read the detailed description
Hamstring muscle is present on posterior region of thigh starting from gluteal region and ending in popliteal fossa. Hamstring has three muscles biceps femoris, semitendinosus and semimembranosus causing flexion at knee joint and help in extension of thigh. Biceps femoris further consists of two heads (long and short head). Long head is supplied by tibial part of the sciatic nerve, while short head is supplied by the common peroneal part of the sciatic nerve. Muscles such as gastro-soleus, tibialis posterior, rectus femoris, iliopsoas, tensor fasica lata, the hamstrings and hip adductors are more likely to be tightened in lower limbs. Muscle tightness can cause the muscle shortness and does not allow full passive or active range of motion. Full active and passive range of motion is only achieved when muscle is flexible.
Tightness of hamstring muscle can occur due to many reasons like injury to the muscle, prolonged sitting hours which are part of different jobs and educational setups. This tightness could lead to strain of the hamstrings, which is the most common occurring injury of the lower limbs. Moreover, hamstring tightness is also correlated with low back pain and lumbar dysfunction. Massage and stretching relax the tightened muscles but cannot normalize the tone or improve their coordination. To achieve this, investigator retrained muscle memory by actively using those respective muscles. Simple stretching of different muscle groups especially hamstrings has been found to improve the extensibility and length of shortened muscles.
Additionally, muscle Energy Techniques (MET) and their related post-isometric relaxation techniques have demonstrated better results in improving flexibility of the tightened muscles. Muscle Energy Techniques are used in soft tissue pathologies in which the patient performs active muscle contraction in specific positions and in specific direction against a force applied by the therapist. The therapist guides and controls the movement with instruction. These are manual techniques that use contraction of the specific muscles and are found to be effective in increasing flexibility of the muscles and improving range of motion. The underlying mechanism through which improvement in extensibility and length occurs is yet unclear and thought to be attributed to both mechanical as well as neurological factors. Firstly MET techniques applied to increase extensibility of the muscles typically involves following steps: stretching the muscle to the limit of barrier or person's tolerance, secondly the person performs an active isometric contraction of the muscle being stretched against a controlled resistance provided by the therapist, additionally the person relaxes the muscle being stretched while the therapist continues holding the stretched position, furthermore the therapist takes up the new range produced by muscle and lengthens it up to a new barrier, and this whole procedure is repeated again according to defined guidelines. The MET techniques can be modified with variations in different components such as force of contraction, duration of the contraction, duration of the stretch and repetitions. This whole process results in increased range of motion and improves flexibility.
Post Isometric Relaxation (PIR) is a type of MET that relaxes the tight muscles with avoidance of initiating stretch reflex. This in turn results in reduced spasm and improved ROM. The relaxation is induced due to isometric contraction of the muscles with facilitation and inhibition. Active Isolated Stretch (AIS) is another type of stretching in which specific movement is performed for a specific muscle with assistance from a therapist or self-assisted (with rope or a band) and those particular movements are repeated again and again to induce a relaxation phenomenon in muscles, fascia and connective tissues. In AIS, movements are monitored carefully to avoid producing any stretch reflex .
A single blind randomized control study was done in Islamabad federal college Islamabad with the duration of 6 months from Jan 2018 to July 2018.the calculated sample size was 35 students (17 in group A and 18 in group B) through open epi . Non probability random sample selection method was used on the behalf of inclusion and exclusion criteria. 22.2+ 2.02 year male and female students of DPT with tight hamstring were included while hamstring injury and any neurological or orthopedic disorder were excluded. The study was approved by the Ethical and Research Committee, and all participants signed the informed consents. Group A was given post isometric relaxation while Group B was given Active isolated stretch for a period of 3 weeks. Outcome measures were assessed at baseline, after first and final exercise session to estimate immediate and short term effects while long term effects were calculated after two weeks of final session of interventions. Semi structured questionnaire was used for subjective and objective assessment. AKE score, sit and reach test score and Lower Extremity Functional Scale questionnaire was used to assess lower extremity functional activities. Sit and reach test was also used to measure hamstring length.
- Conditions
- Hamstring Tightness
- Being tested
- Active Isolated Stretch, Post Isometric Relaxation
- Keywords
- Active isolated stretch, Active knee extension, Post isometric relaxation, Sit and reach test
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Active Isolated StretchOther
In supine position, participant was asked to lock the knee and slowly lift leg using the quadriceps muscles. gentle assistance was given by the rope at the end of the movement, as the quadriceps muscles continue to move the leg. strech was applied for 2 sec and then release to starting position. two sets of 10 repetitions were performed.
Post Isometric RelaxationOther
In supine line, participant was asked to do SLR until resistance was met in hamstring muscles and then was asked to do isometric contraction (10-20% of maximum) for 5 - 10 sec and inhale. After this, patient was asked to exhale while doing so gentle stretch was applied till the new barrier. Starting from this new barrier, the procedure was repeated 2 - 3 times.
| Study group | Role | What they receive |
|---|---|---|
| Post Isometric Relaxation | Active comparator | Post Isometric Relaxation was applied three times a week for the duration of three weeks. Receives: Other: Post Isometric Relaxation |
| Active Isolated stretch | Experimental | Active Isolated stretch was was applied three times a week for the duration of three weeks. Receives: Other: Active Isolated Stretch |
What is being measured
The primary outcome is the main question the study is designed to answer.
Active knee extension score
The Active Knee Extension Test is used to assess hamstring muscle length and the range of active knee extension in the position of hip flexion. The measurement unit is degrees on the goniometer.
Measured: Upto 5 weeks
Secondary outcomes (1)
Sit and reach test
The sit and reach test is a common measure of flexibility, and specifically measures the flexibility of the lower back and hamstring muscles. The score is recorded to the nearest centimeter or half inch as the distance reached by the hand.
Measured: Upto 5 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Jul 2019
- Study start2 Jan 2018
- Primary completion30 Jun 2018
- Study completion30 Jul 2018
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Hamstring TightnessStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 35 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Suman Sheraz, PP-DPT, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04024839
- Sponsor's protocol ID
- RiphahIU Jawad Naweed
- Status last verified
- Jul 2019
- First submitted
- 13 Jul 2019
- Last updated
- 18 Jul 2019
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Feland JB, Myrer JW, Schulthies SS, Fellingham GW, Measom GW. The effect of duration of stretching of the hamstring muscle group for increasing range of motion in people aged 65 years or older. Phys Ther. 2001 May;81(5):1110-7.
PubMed 11319936Handel M, Horstmann T, Dickhuth HH, Gulch RW. Effects of contract-relax stretching training on muscle performance in athletes. Eur J Appl Physiol Occup Physiol. 1997;76(5):400-8. doi: 10.1007/s004210050268.
PubMed 9367279Smith M, Fryer G. A comparison of two muscle energy techniques for increasing flexibility of the hamstring muscle group. J Bodyw Mov Ther. 2008 Oct;12(4):312-7. doi: 10.1016/j.jbmt.2008.06.011. Epub 2008 Aug 6.
PubMed 19083689van Gent RN, Siem D, van Middelkoop M, van Os AG, Bierma-Zeinstra SM, Koes BW. Incidence and determinants of lower extremity running injuries in long distance runners: a systematic review. Br J Sports Med. 2007 Aug;41(8):469-80; discussion 480. doi: 10.1136/bjsm.2006.033548. Epub 2007 May 1.
PubMed 17473005
Study at a glance
From the registry record, last updated by the sponsor on 18 Jul 2019. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Active Isolated Stretch and Post Isometric Relaxation for Hamstring Flexibility in Young Health Adults.
- ClinicalTrials.gov ID
- NCT04024839
- Acronym / sponsor ID
- RiphahIU Jawad Naweed
- Conditions
- Hamstring Tightness
- Keywords
- Active isolated stretch, Active knee extension, Post isometric relaxation, Sit and reach test
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 35 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 2 Jan 2018 (actual)
- Primary completion
- 30 Jun 2018 (actual)
- Study completion
- 30 Jul 2018 (actual)
- First posted
- 18 Jul 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study was intended to compare the immediate, short term and long term effects of active isolated stretch versus post isometric relaxation on hamstring flexibility in young healthy adults.35 students were assigned randomly into two groups with 17 and 18 in each group. Group A was given post isometric relaxation while Group B was Active isolated stretch. 22.2 year male and female students with tight hamstring were included while any neurological and orthopedic disorder were excluded. Active Isolated Stretch and Post Isometric Relaxation at baseline, after first and final exercise session were calculated immediate and short term effects while long term effects were calculated after two weeks of final session.
Detailed description
Hamstring muscle is present on posterior region of thigh starting from gluteal region and ending in popliteal fossa. Hamstring has three muscles biceps femoris, semitendinosus and semimembranosus causing flexion at knee joint and help in extension of thigh. Biceps femoris further consists of two heads (long and short head). Long head is supplied by tibial part of the sciatic nerve, while short head is supplied by the common peroneal part of the sciatic nerve. Muscles such as gastro-soleus, tibialis posterior, rectus femoris, iliopsoas, tensor fasica lata, the hamstrings and hip adductors are more likely to be tightened in lower limbs. Muscle tightness can cause the muscle shortness and does not allow full passive or active range of motion. Full active and passive range of motion is only achieved when muscle is flexible.
Tightness of hamstring muscle can occur due to many reasons like injury to the muscle, prolonged sitting hours which are part of different jobs and educational setups. This tightness could lead to strain of the hamstrings, which is the most common occurring injury of the lower limbs. Moreover, hamstring tightness is also correlated with low back pain and lumbar dysfunction. Massage and stretching relax the tightened muscles but cannot normalize the tone or improve their coordination. To achieve this, investigator retrained muscle memory by actively using those respective muscles. Simple stretching of different muscle groups especially hamstrings has been found to improve the extensibility and length of shortened muscles.
Additionally, muscle Energy Techniques (MET) and their related post-isometric relaxation techniques have demonstrated better results in improving flexibility of the tightened muscles. Muscle Energy Techniques are used in soft tissue pathologies in which the patient performs active muscle contraction in specific positions and in specific direction against a force applied by the therapist. The therapist guides and controls the movement with instruction. These are manual techniques that use contraction of the specific muscles and are found to be effective in increasing flexibility of the muscles and improving range of motion. The underlying mechanism through which improvement in extensibility and length occurs is yet unclear and thought to be attributed to both mechanical as well as neurological factors. Firstly MET techniques applied to increase extensibility of the muscles typically involves following steps: stretching the muscle to the limit of barrier or person's tolerance, secondly the person performs an active isometric contraction of the muscle being stretched against a controlled resistance provided by the therapist, additionally the person relaxes the muscle being stretched while the therapist continues holding the stretched position, furthermore the therapist takes up the new range produced by muscle and lengthens it up to a new barrier, and this whole procedure is repeated again according to defined guidelines. The MET techniques can be modified with variations in different components such as force of contraction, duration of the contraction, duration of the stretch and repetitions. This whole process results in increased range of motion and improves flexibility.
Post Isometric Relaxation (PIR) is a type of MET that relaxes the tight muscles with avoidance of initiating stretch reflex. This in turn results in reduced spasm and improved ROM. The relaxation is induced due to isometric contraction of the muscles with facilitation and inhibition. Active Isolated Stretch (AIS) is another type of stretching in which specific movement is performed for a specific muscle with assistance from a therapist or self-assisted (with rope or a band) and those particular movements are repeated again and again to induce a relaxation phenomenon in muscles, fascia and connective tissues. In AIS, movements are monitored carefully to avoid producing any stretch reflex .
A single blind randomized control study was done in Islamabad federal college Islamabad with the duration of 6 months from Jan 2018 to July 2018.the calculated sample size was 35 students (17 in group A and 18 in group B) through open epi . Non probability random sample selection method was used on the behalf of inclusion and exclusion criteria. 22.2+ 2.02 year male and female students of DPT with tight hamstring were included while hamstring injury and any neurological or orthopedic disorder were excluded. The study was approved by the Ethical and Research Committee, and all participants signed the informed consents. Group A was given post isometric relaxation while Group B was given Active isolated stretch for a period of 3 weeks. Outcome measures were assessed at baseline, after first and final exercise session to estimate immediate and short term effects while long term effects were calculated after two weeks of final session of interventions. Semi structured questionnaire was used for subjective and objective assessment. AKE score, sit and reach test score and Lower Extremity Functional Scale questionnaire was used to assess lower extremity functional activities. Sit and reach test was also used to measure hamstring length.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Post Isometric Relaxation | Active comparator | Other: Post Isometric RelaxationPost Isometric Relaxation was applied three times a week for the duration of three weeks. |
| Active Isolated stretch | Experimental | Other: Active Isolated StretchActive Isolated stretch was was applied three times a week for the duration of three weeks. |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Tight hamstring (Inability to achieve greater than 160° of knee extension with hip at 90° of flexion).
Key exclusion criteria (2 listed)
- Having hamstring injury in past 6 months
- Having any neurological or orthopedic disorder effecting low back and lower limbs.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Active Isolated StretchIn supine position, participant was asked to lock the knee and slowly lift leg using the quadriceps muscles. gentle assistance was given by the rope at the end of the movement, as the quadriceps muscles continue to move the leg. strech was applied for 2 sec and then release to starting position. two sets of 10 repetitions were performed. | Other | Active Isolated stretch |
| Post Isometric RelaxationIn supine line, participant was asked to do SLR until resistance was met in hamstring muscles and then was asked to do isometric contraction (10-20% of maximum) for 5 - 10 sec and inhale. After this, patient was asked to exhale while doing so gentle stretch was applied till the new barrier. Starting from this new barrier, the procedure was repeated 2 - 3 times. | Other | Post Isometric Relaxation |
Primary outcome
Active knee extension score
Time frame: Upto 5 weeks
The Active Knee Extension Test is used to assess hamstring muscle length and the range of active knee extension in the position of hip flexion. The measurement unit is degrees on the goniometer.
1 secondary outcome
Sit and reach test
Time frame: Upto 5 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Jul 2019.
- Background: PubMed 11319936Feland JB, Myrer JW, Schulthies SS, Fellingham GW, Measom GW. The effect of duration of stretching of the hamstring muscle group for increasing range of motion in people aged 65 years or older. Phys Ther. 2001 May;81(5):1110-7.
- Background: PubMed 9367279Handel M, Horstmann T, Dickhuth HH, Gulch RW. Effects of contract-relax stretching training on muscle performance in athletes. Eur J Appl Physiol Occup Physiol. 1997;76(5):400-8. doi: 10.1007/s004210050268.
- Background: PubMed 19083689Smith M, Fryer G. A comparison of two muscle energy techniques for increasing flexibility of the hamstring muscle group. J Bodyw Mov Ther. 2008 Oct;12(4):312-7. doi: 10.1016/j.jbmt.2008.06.011. Epub 2008 Aug 6.
- Background: PubMed 17473005van Gent RN, Siem D, van Middelkoop M, van Os AG, Bierma-Zeinstra SM, Koes BW. Incidence and determinants of lower extremity running injuries in long distance runners: a systematic review. Br J Sports Med. 2007 Aug;41(8):469-80; discussion 480. doi: 10.1136/bjsm.2006.033548. Epub 2007 May 1.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Suman Sheraz, PP-DPT principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Active Isolated Stretch and Post Isometric Relaxation in people with Hamstring Tightness, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 18 Jul 2019. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Active knee extension score (time frame: Upto 5 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04024839, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jul 2019.