Bone Marrow TransplantNCT04115241
Activity Levels in Bone Marrow Transplant Patients
An observational study of Bone Marrow Transplant, run by Michael Tomasson at 1 site in United States.
Trial summary
Participants in this study will be receiving a bone marrow transplant. This study is designed to evaluate correlations between activity levels and length of stay, quality of life, and hand grip strength. Read more about this study
- Who is it for?
- Ages 18 to 99 years
- Conditions the study is for
- Bone Marrow Transplant
- What is being tested?
- Actigraph and Grip strength test
- Type of treatment
- Medical device
- How many people
- 200 participants
- Where
- 1 siteUnited States
- Study dates
- 23 May 2019to 23 May 2030
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 99 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients who will be receiving a bone marrow transplant
Patients who will be receiving a bone marrow transplant are eligible for this study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
University of Iowa
Iowa City, Iowa, 52242
Michael Tomasson, MD, 319-356-4200, michael-tomasson@uiowa.edu
About this study
Participants in this study will be receiving a bone marrow transplant. This study is designed to evaluate correlations between activity levels and length of stay, quality of life, and hand grip strength.
Read the detailed description
Participants in this study will be receiving a bone marrow transplant. Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. Participants will be asked to complete quality of life questionnaires and hand grip tests at three separate time points during their hospitalizations. All data gathered from these activities will be compared with patients' activity levels gathered from the actigraphs both before and during the hospitalization. This study is designed to determine the relationship between activity levels and length of stay, quality of life, and hand grip strength.
- Conditions
- Bone Marrow Transplant
- Being tested
- Actigraph, Grip strength test
- Keywords
- leukemia, multiple myeloma, myelodysplastic syndrome, stem cell transplant
- Medical subject headings
- Leukemia, Multiple Myeloma, Myelodysplastic Syndromes
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ActigraphDevice
Actigraphs are non-invasive, wearable devices that measure activity levels using an accelerometer
Grip strength testOther
The purpose of this test is to measure the maximum isometric strength of the hand and forearm muscles
What is being measured
The primary outcome is the main question the study is designed to answer.
To determine the correlation between activity levels and length of stay in hospital
Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. Activity prior to and during hospitalization will be correlated with length of stay.
Measured: From study intitiation for up to 5 years
To determine the correlation between activity levels and quality of life
Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. They will be provided with quality of life questionnaires at three time points during hospitalization. Activity prior to and during hospitalization will be correlated with quality of life
Measured: From study intitiation for up to 5 years
To determine the correlation between activity levels and hand grip strength
Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. Hand grip strength will be measured at three time points during hospitalization. Activity prior to and during hospitalization will be correlated with hand grip strength.
Measured: From study intitiation for up to 5 years
Secondary outcomes (1)
To determine barriers to activity for patients recovering from bone marrow transplantation and design an intervention to increase activity levels in patients post-transplantation
Barriers to physical activity will be determined using a validated questionnaire at three time points during hospitalization.
Measured: From study intitiation for up to 5 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Oct 2019
- Study start23 May 2019
- Primary completion23 May 2030 (estimated)
- Study completion23 May 2030 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Bone Marrow TransplantStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Prospective
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Michael Tomasson
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Michael Tomasson, University of Iowa
- Investigators
- Michael Tomasson, MD, Principal investigator, University of Iowa
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04115241
- Sponsor's protocol ID
- 202208637-B
- Status last verified
- Nov 2025
- First submitted
- 1 Oct 2019
- Last updated
- 10 Nov 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 10 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Activity Levels in Bone Marrow Transplant Patients
- ClinicalTrials.gov ID
- NCT04115241
- Acronym / sponsor ID
- 202208637-B
- Conditions
- Bone Marrow Transplant
- Keywords
- leukemia, multiple myeloma, myelodysplastic syndrome, stem cell transplant
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- Michael TomassonUniversity, hospital or other
- Study start
- 23 May 2019 (actual)
- Primary completion
- 23 May 2030 (estimated)
- Study completion
- 23 May 2030 (estimated)
- First posted
- 3 Oct 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Participants in this study will be receiving a bone marrow transplant. This study is designed to evaluate correlations between activity levels and length of stay, quality of life, and hand grip strength.
Detailed description
Participants in this study will be receiving a bone marrow transplant. Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. Participants will be asked to complete quality of life questionnaires and hand grip tests at three separate time points during their hospitalizations. All data gathered from these activities will be compared with patients' activity levels gathered from the actigraphs both before and during the hospitalization. This study is designed to determine the relationship between activity levels and length of stay, quality of life, and hand grip strength.
Study design
- Observational model
- Case only
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 99 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients who will be receiving a bone marrow transplant
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ActigraphActigraphs are non-invasive, wearable devices that measure activity levels using an accelerometer | Device | – |
| Grip strength testThe purpose of this test is to measure the maximum isometric strength of the hand and forearm muscles | Other | – |
Primary outcome
To determine the correlation between activity levels and length of stay in hospital
Time frame: From study intitiation for up to 5 years
Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. Activity prior to and during hospitalization will be correlated with length of stay.
To determine the correlation between activity levels and quality of life
Time frame: From study intitiation for up to 5 years
Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. They will be provided with quality of life questionnaires at three time points during hospitalization. Activity prior to and during hospitalization will be correlated with quality of life
To determine the correlation between activity levels and hand grip strength
Time frame: From study intitiation for up to 5 years
Participants will be given actigraphs to wear around their waists starting 3 weeks prior to bone marrow transplants until they are discharged from the hospital. Hand grip strength will be measured at three time points during hospitalization. Activity prior to and during hospitalization will be correlated with hand grip strength.
1 secondary outcome
To determine barriers to activity for patients recovering from bone marrow transplantation and design an intervention to increase activity levels in patients post-transplantation
Time frame: From study intitiation for up to 5 years
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Nov 2025.
- Individual participant dataSharing planned: No
Related trials for Bone Marrow Transplant
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Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
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Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
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Myelofibrosis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Michael Tomasson, MD principal investigator
University of Iowa
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Bone Marrow Transplant, run by Michael Tomasson at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 10 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Michael Tomasson, MD (319-356-4200, melissa-bates@uiowa.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
To determine the correlation between activity levels and length of stay in hospital (time frame: From study intitiation for up to 5 years). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Nov 2025.