Anterior Cruciate Ligament TearNCT04135950
Prospective Registry of Anterior Cruciate Ligament Reconstructions
An observational study of Anterior Cruciate Ligament Tear and Meniscal Tear, run by State University of New York at Buffalo at 1 site in United States.
Trial summary
The purpose of the study is to investigate factors that are associated with outcomes of injury to the anterior cruciate ligament (ACL) in the knee among patients who are undergoing surgical reconstruction. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Anterior Cruciate Ligament Tear, Meniscal Tear, Cartilage Injury
- How many people
- 1,646 participants
- Where
- 1 siteUnited States
- Study dates
- Jan 2005to 28 Oct 2025
- How long will I take part?
- 20 Years
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: All patients at our institution who are having ACL surgery by one of 4 fellowship-trained surgeons will be included in this registry.
Who may be able to join
- Patients undergoing ACL surgery
Who cannot join
- Previous surgery on the affected knee
- Posterior cruciate ligament injuries
- Grade 2 lateral collateral ligament or medial collateral ligament injuries
Trial locations and contacts
1 site in 1 country.
United States1 site
UBMD Orthopaedics and Sports Medicine
Buffalo, New York, 14226
About this study
Official title: Prospective Registry of Predictors and Comorbid Injuries Associated With Anterior Cruciate Ligament Reconstructions
The purpose of the study is to investigate factors that are associated with outcomes of injury to the anterior cruciate ligament (ACL) in the knee among patients who are undergoing surgical reconstruction. This study is a registry of all patients having knee surgery at our institution performed by 4 fellowship-trained orthopaedic surgeons. The surgeon documents patient information on standard data forms including risk factors and surgical findings.
- Medical subject headings
- Anterior Cruciate Ligament Injuries
What is being measured
The primary outcome is the main question the study is designed to answer.
additional injury
At the time of ACL surgery, it is determined if the patient has any other injuries to the meniscus or cartilage.
Measured: intraoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Oct 2019
- Study startJan 2005
- Primary completion28 Oct 2025
- Study completion28 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anterior Cruciate Ligament TearStudies of the same condition, open and under way.
- More trials run by State University of New York at BuffaloThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 1,646 participants (actual)
- Target duration
- 20 Years
Sponsor and investigators
- Lead sponsor
- State University of New York at Buffalo
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Leslie Bisson, State University of New York at Buffalo
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04135950
- Sponsor's protocol ID
- 441874-2
- Status last verified
- Nov 2025
- First submitted
- 21 Oct 2019
- Last updated
- 20 Nov 2025
- Results posted
- No
- Data monitoring committee
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prospective Registry of Predictors and Comorbid Injuries Associated With Anterior Cruciate Ligament Reconstructions
- ClinicalTrials.gov ID
- NCT04135950
- Acronym / sponsor ID
- 441874-2
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 1,646 participants (actual)
- Lead sponsor
- State University of New York at BuffaloUniversity, hospital or other
- Study start
- Jan 2005 (actual)
- Primary completion
- 28 Oct 2025 (actual)
- Study completion
- 28 Oct 2025 (actual)
- First posted
- 23 Oct 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of the study is to investigate factors that are associated with outcomes of injury to the anterior cruciate ligament (ACL) in the knee among patients who are undergoing surgical reconstruction. This study is a registry of all patients having knee surgery at our institution performed by 4 fellowship-trained orthopaedic surgeons. The surgeon documents patient information on standard data forms including risk factors and surgical findings.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Target follow-up
- 20 Years
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- All patients at our institution who are having ACL surgery by one of 4 fellowship-trained surgeons will be included in this registry.
Key inclusion criteria (1 listed)
- Patients undergoing ACL surgery
Key exclusion criteria (3 listed)
- Previous surgery on the affected knee
- Posterior cruciate ligament injuries
- Grade 2 lateral collateral ligament or medial collateral ligament injuries
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
additional injury
Time frame: intraoperatively
At the time of ACL surgery, it is determined if the patient has any other injuries to the meniscus or cartilage.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Nov 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Anterior Cruciate Ligament Tear and Meniscal Tear, run by State University of New York at Buffalo at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
additional injury (time frame: intraoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Nov 2025.