Cardiac DeathNCT04295291
Quality of Cardiopulmonary Resuscitation Pre- and Intra Hospital
An observational study of Cardiac Death and Cardiac Arrest, run by Ostfold University College.
Trial summary
The survival after intrahospital cardiac arrest has been reported to 15%. In Norway this varies between 16 and 23%.). Many factors are associated with survival after cardiac arrest, both intra- and prehospital. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Cardiac Death, Cardiac Arrest, Cardiac Arrhythmia
- How many people
- 300 participants
- Where
- No sites listed yet
- Study dates
- 1 Jan 2026to 31 Dec 2028
- How long will I take part?
- 6 Months
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: All patients with cardiac arrest, treated with cardio-pumonary resusciation and the use of a defirbillator with USB memory stick installed (all 71 in the current hospital)
Who may be able to join
- cardiac arrest (all reasons)
- a defibrillator has been used
- over 18 years
- cardiopulmonary resuscitation has been conducted
Who cannot join
None listed.
About this study
The survival after intrahospital cardiac arrest has been reported to 15%. In Norway this varies between 16 and 23%.). Many factors are associated with survival after cardiac arrest, both intra- and prehospital. Recent studies have not included information about individual patient factors and the outcome after cardiopulmonary resuscitation (CPR). In the current hospital, we are able to record patient specific information related to a cardiac arrest/CPR situation, and thereby be able to assess patient-related factors associated with both detection, treatment and outcome of CPR.
Read the detailed description
Several factors have been associated with survival, e.g. to monitor hands-off time(Odds ratio, OR, for 2.48, 95% KI 1.11-5.56, p=.03), monthly assessment of all cardiac arrest cases (OR 6.9, 95% KI 1.41-33.92), and includin av local coordinator for CPR (OR 2.93, 95% KI 1.08-7.94, p=.03), as well as depth of compressions. Nevertheless, information about cardiac arrests and CPR have not been assessed in relation to patient specific information. In the current hospital, we are able to record the CPR sequence, and see this in relation to other patient- and case- specific information such as initial cardiac rythm, time to first compression, hands-off time, quality of CPR, and factors affecting the treatment and outcome.
The hospital has 71 registered defibrillators used in CPR. The current study will both gather retrospective data- not seen in relation to patient specific information, and prospective data related to specific patients.
- Conditions
- Cardiac Death, Cardiac Arrest, Cardiac Arrhythmia, Cardiac Disease
- Keywords
- Cardiopulmonary resuscitation, Defibrillation, Ventilation, Quality, Mortality, Morbidity
- Medical subject headings
- Death, Heart Arrest, Arrhythmias, Cardiac, Heart Diseases, Respiratory Aspiration
What is being measured
The primary outcome is the main question the study is designed to answer.
Mortality
Patient dead or alive
Measured: up to 30 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Mar 2020
- Study start1 Jan 2026 (estimated)
- Primary completion31 Dec 2027 (estimated)
- Study completion31 Dec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cardiac DeathStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Other
- Enrolment
- 300 participants (estimated)
- Target duration
- 6 Months
Sponsor and investigators
- Lead sponsor
- Ostfold University College
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ann-Chatrin Leonardsen, Ostfold University College
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04295291
- Sponsor's protocol ID
- AB 3418
- Status last verified
- Aug 2025
- First submitted
- 5 Jan 2020
- Last updated
- 5 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Quality of Cardiopulmonary Resuscitation Pre- and Intra Hospital
- ClinicalTrials.gov ID
- NCT04295291
- Acronym / sponsor ID
- AB 3418
- Conditions
- Cardiac Death, Cardiac Arrest, Cardiac Arrhythmia, Cardiac Disease
- Keywords
- Cardiopulmonary resuscitation, Defibrillation, Ventilation, Quality, Mortality, Morbidity
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 300 participants (estimated)
- Lead sponsor
- Ostfold University CollegeUniversity, hospital or other
- Study start
- 1 Jan 2026 (estimated)
- Primary completion
- 31 Dec 2027 (estimated)
- Study completion
- 31 Dec 2028 (estimated)
- First posted
- 4 Mar 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The survival after intrahospital cardiac arrest has been reported to 15%. In Norway this varies between 16 and 23%.). Many factors are associated with survival after cardiac arrest, both intra- and prehospital. Recent studies have not included information about individual patient factors and the outcome after cardiopulmonary resuscitation (CPR). In the current hospital, we are able to record patient specific information related to a cardiac arrest/CPR situation, and thereby be able to assess patient-related factors associated with both detection, treatment and outcome of CPR.
Detailed description
Several factors have been associated with survival, e.g. to monitor hands-off time(Odds ratio, OR, for 2.48, 95% KI 1.11-5.56, p=.03), monthly assessment of all cardiac arrest cases (OR 6.9, 95% KI 1.41-33.92), and includin av local coordinator for CPR (OR 2.93, 95% KI 1.08-7.94, p=.03), as well as depth of compressions. Nevertheless, information about cardiac arrests and CPR have not been assessed in relation to patient specific information. In the current hospital, we are able to record the CPR sequence, and see this in relation to other patient- and case- specific information such as initial cardiac rythm, time to first compression, hands-off time, quality of CPR, and factors affecting the treatment and outcome.
The hospital has 71 registered defibrillators used in CPR. The current study will both gather retrospective data- not seen in relation to patient specific information, and prospective data related to specific patients.
Study design
- Observational model
- Cohort
- Time perspective
- Other
- Target follow-up
- 6 Months
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- All patients with cardiac arrest, treated with cardio-pumonary resusciation and the use of a defirbillator with USB memory stick installed (all 71 in the current hospital)
Key inclusion criteria (4 listed)
- cardiac arrest (all reasons)
- a defibrillator has been used
- over 18 years
- cardiopulmonary resuscitation has been conducted
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Mortality
Time frame: up to 30 days
Patient dead or alive
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Aug 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Cardiac Death and Cardiac Arrest, run by Ostfold University College.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 5 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mortality (time frame: up to 30 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Aug 2025.