COVID-19 VaccinationNCT04376515
HOPE Intervention for COVID-19
A study testing HOPE intervention in people with COVID-19 Vaccination, run by University of California, Irvine at 1 site in United States.
Trial summary
The Harnessing Online Peer Education COVID-19 (HOPE COVID-19) intervention will assess whether a peer-led online support community can improve behavioral health outcomes related to COVID-19. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- COVID-19 Vaccination
- What is being tested?
- HOPE intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 120 participants
- Where
- 1 siteUnited States
- Study dates
- 23 Jul 2021to 30 Sep 2021
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- 18-30 years old
- English speakers only
- U.S. Resident
- Part of phase 1a or 1b of COVID-19 vaccine rollout (Healthcare personnel, education, and frontline essential workers, verified through LinkedIn profile)
- Uses social media and/or online communities greater than twice per week
- Has, or is willing to accept a friend request and group invite from our Facebook social media page
- Have not received a COVID-19 vaccine and do not have medical conditions or other circumstances preventing them from receiving one
Who cannot join
- -
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Harnessing Online Peer Education Online Support Intervention for COVID-19 (HOPE COVID-19)
The Harnessing Online Peer Education COVID-19 (HOPE COVID-19) intervention will assess whether a peer-led online support community can improve behavioral health outcomes related to COVID-19.
Read the detailed description
The Harnessing Online Peer Education COVID-19 (HOPE COVID-19) intervention will assess whether a peer-led online support community can improve behavioral health outcomes related to COVID-19. Participants in the intervention group will be assigned to peer leaders trained in the HOPE intervention methods.
- Conditions
- COVID-19 Vaccination
- Being tested
- HOPE intervention
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
HOPE interventionBehavioural
Online peer support community of peers trained in behavior change science
| Study group | Role | What they receive |
|---|---|---|
| HOPE Intervention | Experimental | HOPE peer-led intervention Receives: Behavioral: HOPE intervention |
| Control | No intervention | Control group- online community without peer leaders |
What is being measured
The primary outcome is the main question the study is designed to answer.
Requests for a COVID-19 Vaccine Resource Sheet
Whether or not the participant requested that our study team send them an electronic resource sheet on the COVID-19 vaccine and where they can get vaccinated.
Measured: 1 time request during the 4-week study
Secondary outcomes (1)
Proof of COVID-19 Vaccination
Whether or not a participant sent us a proof of a COVID-19 Vaccination
Measured: 1 time proof during 4-week study and up to 2 weeks after
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 May 2020
- Study start23 Jul 2021
- Primary completion30 Sep 2021
- Study completion30 Sep 2021
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for COVID-19 VaccinationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 120 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of California, Irvine
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sean D Young, University of California, Irvine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04376515
- Sponsor's protocol ID
- 400
- Status last verified
- Oct 2024
- First submitted
- 31 Mar 2020
- Last updated
- 2 May 2025
- Results posted
- Yes, on ClinicalTrials.gov
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Ugarte DA, Lin J, Qian T, Young SD. An online community peer support intervention to promote COVID-19 vaccine information among essential workers: a randomized trial. Ann Med. 2022 Dec;54(1):3079-3084. doi: 10.1080/07853890.2022.2138960.
PubMed 36314847
Study at a glance
From the registry record, last updated by the sponsor on 2 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Harnessing Online Peer Education Online Support Intervention for COVID-19 (HOPE COVID-19)
- ClinicalTrials.gov ID
- NCT04376515
- Acronym / sponsor ID
- 400
- Conditions
- COVID-19 Vaccination
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 120 participants (actual)
- Lead sponsor
- University of California, IrvineUniversity, hospital or other
- Study start
- 23 Jul 2021 (actual)
- Primary completion
- 30 Sep 2021 (actual)
- Study completion
- 30 Sep 2021 (actual)
- First posted
- 6 May 2020 (actual)
- Results
- Posted 2 May 2025
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The Harnessing Online Peer Education COVID-19 (HOPE COVID-19) intervention will assess whether a peer-led online support community can improve behavioral health outcomes related to COVID-19.
Detailed description
The Harnessing Online Peer Education COVID-19 (HOPE COVID-19) intervention will assess whether a peer-led online support community can improve behavioral health outcomes related to COVID-19. Participants in the intervention group will be assigned to peer leaders trained in the HOPE intervention methods.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| HOPE Intervention | Experimental | Behavioral: HOPE interventionHOPE peer-led intervention |
| Control | No intervention | –Control group- online community without peer leaders |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (7 listed)
- 18-30 years old
- English speakers only
- U.S. Resident
- Part of phase 1a or 1b of COVID-19 vaccine rollout (Healthcare personnel, education, and frontline essential workers, verified through LinkedIn profile)
- Uses social media and/or online communities greater than twice per week
Key exclusion criteria (1 listed)
- -
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| HOPE interventionOnline peer support community of peers trained in behavior change science | Behavioural | HOPE Intervention |
Primary outcome
Requests for a COVID-19 Vaccine Resource Sheet
Time frame: 1 time request during the 4-week study
Whether or not the participant requested that our study team send them an electronic resource sheet on the COVID-19 vaccine and where they can get vaccinated.
1 secondary outcome
Proof of COVID-19 Vaccination
Time frame: 1 time proof during 4-week study and up to 2 weeks after
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 May 2025.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Derived from this study: PubMed 36314847Ugarte DA, Lin J, Qian T, Young SD. An online community peer support intervention to promote COVID-19 vaccine information among essential workers: a randomized trial. Ann Med. 2022 Dec;54(1):3079-3084. doi: 10.1080/07853890.2022.2138960.
Related trials for COVID-19 Vaccination
Not yet recruitingPhase 2
Study of VYD2311 for the Treatment of Adults With Long-COVID or Post-Vaccination Syndrome
Long COVID, COVID-19 (SARS-CoV-2 Infection)
RecruitingObservational study
Women s Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH)
Mental Health
Not yet recruitingPhase 3
Study of a Combination SARS-CoV-2 Recombinant Spike and High-Dose Inactivated Influenza Vaccine With Matrix-M Adjuvant in Adult Participants 60 Years of Age and Older
Immunization, Healthy Volunteers
Recruiting
Testimonials and Navigation in Rheumatology
Rheumatologic Disease, Autoimmune Diseases
Not yet recruitingObservational study
Assessment of the Acceptability of, and Factors Associated With, Recommended Vaccinations During Pregnancy in Maternity Units in the Ile-de-France Region
Vaccination Coverage Among Pregnant Women
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing HOPE intervention in people with COVID-19 Vaccination, run by University of California, Irvine at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 2 May 2025). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Requests for a COVID-19 Vaccine Resource Sheet (time frame: 1 time request during the 4-week study). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04376515, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 May 2025.