Exercise, Cardiovascular Function, Fatigue, Muscular PowerNCT04448925
Physiological Responses to Maximal 4-s Sprint Interval Cycling
A study testing inertial-load exercise (ILE) in people with Exercise, Cardiovascular Function, Fatigue, Muscular Power, run by University of Texas at Austin at 1 site in United States.
Trial summary
The optimal recovery duration depends on the intensity of exercise and in the present study the intensity was maximal power for 4-s while cycling an 'Inertial Load' ergometer (ILE). Recovery duration of 15, 30 and 45-s were given between 30 successive sprints. Read more about this study
- Who is it for?
- Ages 18 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Exercise, Cardiovascular Function, Fatigue, Muscular Power
- What is being tested?
- inertial-load exercise (ILE)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 16 participants
- Where
- 1 siteUnited States
- Study dates
- 10 Jan 2019to 20 Jun 2020
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- healthy participants
Who cannot join
- unhealthy
Trial locations and contacts
1 site in 1 country.
United States1 site
University of Texas at Austin Human Performance Laboratory
Austin, Texas, 78712
About this study
Official title: Physiological Responses to Maximal 4-s Sprint Interval Cycling Using Inertial Loading: the Influence of Inter-sprint Recovery Duration
The optimal recovery duration depends on the intensity of exercise and in the present study the intensity was maximal power for 4-s while cycling an 'Inertial Load' ergometer (ILE). Recovery duration of 15, 30 and 45-s were given between 30 successive sprints.
Read the detailed description
All subjects completed an informed consent for this study that was approved by the Institutional Review Board of the University of Texas at Austin.
Study Overview. A randomized, cross-over experimental design was conducted. Each participant visited the laboratory on four occasions which were separated by two to five days. Measurement of body mass, familiarization with experimental procedures and cycling peak oxygen consumption test (VO2peak) were performed on the first visit. Participants took part in inertial-load exercise (ILE) on the remaining test days. On each separate session, a different inter-sprint recovery duration was employed (i.e. 15, 30 or 45-s). Cycling power output, pulmonary gas exchange, vastus lateralis de-oxygenation status, heart rate and blood lactate were measured.
- Being tested
- inertial-load exercise (ILE)
- Medical subject headings
- Motor Activity, Fatigue
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
inertial-load exercise (ILE)Other
Length of time between exercise bouts
| Study group | Role | What they receive |
|---|---|---|
| Recovery duration 15 seconds | Experimental | Resting for 15 sec Receives: Other: inertial-load exercise (ILE) |
| Recovery duration 30 seconds | Experimental | Resting for 30 sec Receives: Other: inertial-load exercise (ILE) |
| Recovery duration 45 seconds | Experimental | Resting for 45 sec Receives: Other: inertial-load exercise (ILE) |
What is being measured
The primary outcome is the main question the study is designed to answer.
maximal leg power
Measured: 10 min
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Jun 2020
- Study start10 Jan 2019
- Primary completion20 Jul 2019
- Study completion20 Jun 2020
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Exercise, Cardiovascular Function, Fatigue, Muscular PowerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Model description
- Repeated measures, cross-over
- Masking
- None (open label)
- Enrolment
- 16 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Texas at Austin
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04448925
- Sponsor's protocol ID
- UTexasAustinHPL
- Status last verified
- Jun 2020
- First submitted
- 23 Jun 2020
- Last updated
- 26 Jun 2020
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: all data will be grouped and averaged
Publications
Vardarli E, Satiroglu R, Allen JR, Bjellquist-Ledger R, Burton HM, Coyle EF. Physiological responses to maximal 4 s sprint interval cycling using inertial loading: the influence of inter-sprint recovery duration. Eur J Appl Physiol. 2021 Aug;121(8):2295-2304. doi: 10.1007/s00421-021-04677-6. Epub 2021 May 11.
PubMed 33974126
Study at a glance
From the registry record, last updated by the sponsor on 26 Jun 2020. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Physiological Responses to Maximal 4-s Sprint Interval Cycling Using Inertial Loading: the Influence of Inter-sprint Recovery Duration
- ClinicalTrials.gov ID
- NCT04448925
- Acronym / sponsor ID
- UTexasAustinHPL
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 16 participants (actual)
- Lead sponsor
- University of Texas at AustinUniversity, hospital or other
- Study start
- 10 Jan 2019 (actual)
- Primary completion
- 20 Jul 2019 (actual)
- Study completion
- 20 Jun 2020 (actual)
- First posted
- 26 Jun 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The optimal recovery duration depends on the intensity of exercise and in the present study the intensity was maximal power for 4-s while cycling an 'Inertial Load' ergometer (ILE). Recovery duration of 15, 30 and 45-s were given between 30 successive sprints.
Detailed description
All subjects completed an informed consent for this study that was approved by the Institutional Review Board of the University of Texas at Austin.
Study Overview. A randomized, cross-over experimental design was conducted. Each participant visited the laboratory on four occasions which were separated by two to five days. Measurement of body mass, familiarization with experimental procedures and cycling peak oxygen consumption test (VO2peak) were performed on the first visit. Participants took part in inertial-load exercise (ILE) on the remaining test days. On each separate session, a different inter-sprint recovery duration was employed (i.e. 15, 30 or 45-s). Cycling power output, pulmonary gas exchange, vastus lateralis de-oxygenation status, heart rate and blood lactate were measured.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- Repeated measures, cross-over
| Arm | Type | Receives |
|---|---|---|
| Recovery duration 15 seconds | Experimental | Other: inertial-load exercise (ILE)Resting for 15 sec |
| Recovery duration 30 seconds | Experimental | Other: inertial-load exercise (ILE)Resting for 30 sec |
| Recovery duration 45 seconds | Experimental | Other: inertial-load exercise (ILE)Resting for 45 sec |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- healthy participants
Key exclusion criteria (1 listed)
- unhealthy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| inertial-load exercise (ILE)Length of time between exercise bouts | Other | Recovery duration 15 seconds, Recovery duration 30 seconds, Recovery duration 45 seconds |
Primary outcome
maximal leg power
Time frame: 10 min
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jun 2020.
- Derived from this study: PubMed 33974126Vardarli E, Satiroglu R, Allen JR, Bjellquist-Ledger R, Burton HM, Coyle EF. Physiological responses to maximal 4 s sprint interval cycling using inertial loading: the influence of inter-sprint recovery duration. Eur J Appl Physiol. 2021 Aug;121(8):2295-2304. doi: 10.1007/s00421-021-04677-6. Epub 2021 May 11.
- Individual participant dataSharing planned: No. all data will be grouped and averaged
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing inertial-load exercise (ILE) in people with Exercise, Cardiovascular Function, Fatigue, Muscular Power, run by University of Texas at Austin at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Jun 2020. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
maximal leg power (time frame: 10 min). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04448925, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jun 2020.