Work-Related ConditionPRORISKNCT04459793
The Danish Occupational Medicine Cohort - Long-term Prognosis for Patients With Work-related Disorders
An observational study of Work-Related Condition, run by Regional Hospital West Jutland at 1 site in Denmark.
Trial summary
Each year about 10.000 patients are referred due to suspected work-related disorders to the Danish departments of occupational medicine. In Denmark and internationally there is a lack of follow-up studies investigating the long-term prognosis of employees with work-related disorders. Read more about this study
- Who is it for?
- Ages 16 years and older
- Conditions the study is for
- Work-Related Condition
- How many people
- 145,521 participants
- Where
- 1 siteDenmark
- Study dates
- 1 Jan 2000to 31 Dec 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 years and older
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: The cohort was created through The Danish National Patient Register and comprises all patients seen in Danish Departments of Occupational Medicine from 2000-2018 (N= 145.521). Numerous register data are included in the database from five years prior to time of inclusion until 2018. The cohort will be updated with new patients and register data regularly.
Who may be able to join
- A record of contact at Danish departments of occupational medicine with a relevant primary or secondary diagnosis according to the International Classification of Diseases, 10th revision.
Who cannot join
- No record of contact or only a record of referral without subsequent records of relevant primary or secondary diagnosis.
Trial locations and contacts
1 site in 1 country.
About this study
Each year about 10.000 patients are referred due to suspected work-related disorders to the Danish departments of occupational medicine. In Denmark and internationally there is a lack of follow-up studies investigating the long-term prognosis of employees with work-related disorders. To facilitate long-term prognostic studies for work-related conditions a Danish Occupational Medicine Cohort has been established through the Danish population registers.
Read the detailed description
Danish departments of occupational medicine examine around 10,000 patients each year referred due to suspected work-related disorders. In Denmark and internationally there is a lack of follow-up studies investigating the long-term prognosis of employees with work-related disorders. The purpose of this cohort is to facilitate long-term prognostic studies for conditions such as mental or musculoskeletal disorders.
The Danish Occupational Medicine cohort has been created through The Danish National Patient Register and comprises all patients seen in Danish Departments of Occupational Medicine from 2000-2018 (N=145.521). Numerous register data are included in the database from five years prior to time of inclusion until 2018. Examples of register data are; information on work, sickness absence and disability as well as number and type of contacts to health services, use of medication, income, education, type of occupation, social status, death and cause of death. Job Exposure Matrices (JEMs) on physical and psychosocial work exposure, life styles and other matrices are also available. The cohort will be updated with new patients and register data regularly.
- Conditions
- Work-Related Condition
- Keywords
- Prognosis, Work-related disorders, Occupational medicine
What is being measured
The primary outcome is the main question the study is designed to answer.
Annual work participation score
Work participation score is defined as number of weeks of employment relative to the total sum of number of weeks of employment plus number of weeks on temporary or permanent health related public compensation as registered by the Danish National Register on Public Transfer Payments register (DREAM).
Measured: 5 years
Annual health care utilization
Primary and secondary Health care contacts - includes all face to face contacts from the Danish National Health Service Register and Danish National Patient Register
Measured: 5 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Jul 2020
- Study start1 Jan 2000
- Primary completion31 Dec 2025 (estimated)
- Study completion31 Dec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Work-Related ConditionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 145,521 participants (actual)
Sponsor and investigators
- Lead sponsor
- Regional Hospital West Jutland
- Sponsor type
- University, hospital or other
- Collaborators
- Aarhus University Hospital Skejby, University of Aarhus, Aalborg University Hospital
- Responsible party
- Principal investigator, David H Christiansen, Regional Hospital West Jutland
- Investigators
- David H Christiansen, Principal investigator, Occupational Medicine, Regional Hospital Herning
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04459793
- Sponsor's protocol ID
- DST7055
- Acronym
- PRORISK
- Status last verified
- Sep 2021
- First submitted
- 1 Jul 2020
- Last updated
- 16 Sep 2021
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Persson ML, Willert MV, Kyndi M, Dalgaard VL. Work participation and disability pension after work-related PTSD: trajectories and impact of occupation. Occup Environ Med. 2026 Feb 12;82(12):589-596. doi: 10.1136/oemed-2025-110412.
PubMed 41633844Willert MV, Christiansen DH, Dalgaard L, Vestergaard JM, Andersen JH, Kyndi M. Developing prognostic models for health care utilization in patients with work-related mental health problems. BMC Health Serv Res. 2023 Aug 7;23(1):834. doi: 10.1186/s12913-023-09802-z.
PubMed 37550656
Study at a glance
From the registry record, last updated by the sponsor on 16 Sep 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Danish Occupational Medicine Cohort - Long-term Prognosis for Patients With Work-related Disorders
- ClinicalTrials.gov ID
- NCT04459793
- Acronym / sponsor ID
- PRORISK / DST7055
- Conditions
- Work-Related Condition
- Keywords
- Prognosis, Work-related disorders, Occupational medicine
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 145,521 participants (actual)
- Lead sponsor
- Regional Hospital West JutlandUniversity, hospital or other
- Collaborators
- Aarhus University Hospital Skejby, University of Aarhus, Aalborg University Hospital
- Study start
- 1 Jan 2000 (actual)
- Primary completion
- 31 Dec 2025 (estimated)
- Study completion
- 31 Dec 2025 (estimated)
- First posted
- 7 Jul 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Each year about 10.000 patients are referred due to suspected work-related disorders to the Danish departments of occupational medicine. In Denmark and internationally there is a lack of follow-up studies investigating the long-term prognosis of employees with work-related disorders. To facilitate long-term prognostic studies for work-related conditions a Danish Occupational Medicine Cohort has been established through the Danish population registers.
Detailed description
Danish departments of occupational medicine examine around 10,000 patients each year referred due to suspected work-related disorders. In Denmark and internationally there is a lack of follow-up studies investigating the long-term prognosis of employees with work-related disorders. The purpose of this cohort is to facilitate long-term prognostic studies for conditions such as mental or musculoskeletal disorders.
The Danish Occupational Medicine cohort has been created through The Danish National Patient Register and comprises all patients seen in Danish Departments of Occupational Medicine from 2000-2018 (N=145.521). Numerous register data are included in the database from five years prior to time of inclusion until 2018. Examples of register data are; information on work, sickness absence and disability as well as number and type of contacts to health services, use of medication, income, education, type of occupation, social status, death and cause of death. Job Exposure Matrices (JEMs) on physical and psychosocial work exposure, life styles and other matrices are also available. The cohort will be updated with new patients and register data regularly.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 16 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- The cohort was created through The Danish National Patient Register and comprises all patients seen in Danish Departments of Occupational Medicine from 2000-2018 (N= 145.521). Numerous register data are included in the database from five years prior to time of inclusion until 2018. The cohort will be updated with new patients and register data regularly.
Key inclusion criteria (1 listed)
- A record of contact at Danish departments of occupational medicine with a relevant primary or secondary diagnosis according to the International Classification of Diseases, 10th revision.
Key exclusion criteria (1 listed)
- No record of contact or only a record of referral without subsequent records of relevant primary or secondary diagnosis.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Annual work participation score
Time frame: 5 years
Work participation score is defined as number of weeks of employment relative to the total sum of number of weeks of employment plus number of weeks on temporary or permanent health related public compensation as registered by the Danish National Register on Public Transfer Payments register (DREAM).
Annual health care utilization
Time frame: 5 years
Primary and secondary Health care contacts - includes all face to face contacts from the Danish National Health Service Register and Danish National Patient Register
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Sep 2021.
- Derived from this study: PubMed 41633844Persson ML, Willert MV, Kyndi M, Dalgaard VL. Work participation and disability pension after work-related PTSD: trajectories and impact of occupation. Occup Environ Med. 2026 Feb 12;82(12):589-596. doi: 10.1136/oemed-2025-110412.
- Derived from this study: PubMed 37550656Willert MV, Christiansen DH, Dalgaard L, Vestergaard JM, Andersen JH, Kyndi M. Developing prognostic models for health care utilization in patients with work-related mental health problems. BMC Health Serv Res. 2023 Aug 7;23(1):834. doi: 10.1186/s12913-023-09802-z.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
David H Christiansen principal investigator
Occupational Medicine, Regional Hospital Herning
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Work-Related Condition, run by Regional Hospital West Jutland at 1 site in Denmark.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 16 Sep 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Denmark. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Annual work participation score (time frame: 5 years). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04459793, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Sep 2021.