Cardiovascular DiseasesPMPNCT04484662
Potted Mint Plants
A study testing Potted Mint Plants in people with Cardiovascular Diseases, run by National Taiwan University Hospital at 1 site in Taiwan.
Trial summary
This study will recruit 60 subjects, in sum of 30 families. We will measure 2 indoor environments (living room and bedroom) for All-in-one monitoring the indoor air quality, in which collected culturable fungus and bacteria indoor to calculate colony forming unit (CFU). Read more about this study
- Who is it for?
- Ages 20 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Cardiovascular Diseases
- What is being tested?
- Potted Mint Plants
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTaiwan
- Study dates
- 9 Nov 2020to 31 Jul 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- in the Department of Cardiology or inpatients at National Taiwan University Hospital
- aged 20-80
- live in the Greater Taipei area
Who cannot join
- The research subjects must agree to cooperate with the health assessment.
- serious brain, heart disease and mental illness
- uncomfortable reactions
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Potted Mint Plants on Indoor Air Quality and the Concentration of Bacterium and Fungus, and Evaluation of Cardiovascular Health
This study will recruit 60 subjects, in sum of 30 families. We will measure 2 indoor environments (living room and bedroom) for All-in-one monitoring the indoor air quality, in which collected culturable fungus and bacteria indoor to calculate colony forming unit (CFU). We will apply Kore Technology (MS-200) (Electron Ionization time-of-flight mass spectrometry, EI-TOF-MS) to measure the indoor volatile organic chemicals (VOCs) before intervention and perform repeated measurements of VOCs and the concentration of phytoncides before intervention and one week later after placing potted plants into indoor environments (living room and bedroom).
In conclusion, this study aims to investigate the clinical utility of potted mint plants in reducing indoor bacterial and fungal growth and indoor air pollution, and cardiovascular benefits. Furthermore, the possible application of indoor potted mint plant in antiviral influenza or pneumonia in the future.
Read the detailed description
The contribution of air pollution is a very important public health issue for human health. Indoor air quality may have more influence on human health than outdoor air pollution. Previous studies indicate indoor air pollution which causes respiratory disease has been associated with cardiovascular disease. Besides, some studies showed that indoor CO2 concentration was positively correlated with virus detection and bacterial concentration in the air, and coagulase-negative staphylococci (CNS) was detected in many poorly ventilated indoor environments. Mint can release chemical substance to inhibit viruses and bacteria. Among the components, the menthol and terpineol induced vasodilation so as to reduce blood pressure. For the pilot study we have finished the qualitative and quantitative research in chemical components released by the mint.
Therefore, this study aims to evaluate the indoor air quality and the distribution of fungal and bacterial concentration in the indoor environment, analyze the effect of potted mint plants on indoor air quality, fungal and bacterial concentration, and explore the correlation between the intervention of potted mint plants and cardiovascular health.
This study will recruit 60 subjects, in sum of 30 families. We will measure 2 indoor environments (living room and bedroom) for All-in-one monitoring the indoor air quality, in which collected culturable fungus and bacteria indoor to calculate colony forming unit (CFU). We will apply Kore Technology (MS-200) (Electron Ionization time-of-flight mass spectrometry, EI-TOF-MS) to measure the indoor volatile organic chemicals (VOCs) before intervention and perform repeated measurements of VOCs and the concentration of phytoncides before intervention and one week later after placing potted plants into indoor environments (living room and bedroom).
Furthermore, we used matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) to identify microbiology; simultaneously, we record the outdoor environment and indoor ventilation. To assess subjects' cardiovascular health, we use DynaPulse to evaluate their cardiovascular function, and make them equipped with Holter electrocardiography (ECG) to continuously monitor the trend of heart rate variability (HRV) before and after intervention.
In conclusion, this study aims to investigate the clinical utility of potted mint plants in reducing indoor bacterial and fungal growth and indoor air pollution, and cardiovascular benefits. Furthermore, the possible application of indoor potted mint plant in antiviral influenza or pneumonia in the future.
- Conditions
- Cardiovascular Diseases
- Being tested
- Potted Mint Plants
- Keywords
- Potted mint plants, Indoor air quality, Fungus, Bacteria, Cardiovascular health
- Medical subject headings
- Cardiovascular Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Potted Mint PlantsOther
We will measure 2 indoor environments (living room and bedroom) for placing potted plants.
| Study group | Role | What they receive |
|---|---|---|
| Potted Mint Plants Intervention | Other | We will measure 2 indoor environments (living room and bedroom) for placing potted plants. We will analyze the effect of potted mint plants on indoor air quality, fungal and bacterial concentration, and explore the correlation between the intervention of potted mint plants and cardiovascular health. Receives: Other: Potted Mint Plants |
What is being measured
The primary outcome is the main question the study is designed to answer.
Improve Indoor Air Quality
Measured: one week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jul 2020
- Study start9 Nov 2020
- Primary completion12 Nov 2020
- Study completion31 Jul 2021 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cardiovascular DiseasesStudies of the same condition, open and under way.
- More trials run by National Taiwan University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- This study will recruit 60 subjects, in sum of 30 families.
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Taiwan University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Su ta chen, PI, Principal investigator, NTUH
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04484662
- Sponsor's protocol ID
- 202005078RIND
- Acronym
- PMP
- Status last verified
- Jul 2020
- First submitted
- 21 Jul 2020
- Last updated
- 1 Dec 2020
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 1 Dec 2020. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Potted Mint Plants on Indoor Air Quality and the Concentration of Bacterium and Fungus, and Evaluation of Cardiovascular Health
- ClinicalTrials.gov ID
- NCT04484662
- Acronym / sponsor ID
- PMP / 202005078RIND
- Conditions
- Cardiovascular Diseases
- Keywords
- Potted mint plants, Indoor air quality, Fungus, Bacteria, Cardiovascular health
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- National Taiwan University HospitalUniversity, hospital or other
- Study start
- 9 Nov 2020 (actual)
- Primary completion
- 12 Nov 2020 (actual)
- Study completion
- 31 Jul 2021 (estimated)
- First posted
- 23 Jul 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will recruit 60 subjects, in sum of 30 families. We will measure 2 indoor environments (living room and bedroom) for All-in-one monitoring the indoor air quality, in which collected culturable fungus and bacteria indoor to calculate colony forming unit (CFU). We will apply Kore Technology (MS-200) (Electron Ionization time-of-flight mass spectrometry, EI-TOF-MS) to measure the indoor volatile organic chemicals (VOCs) before intervention and perform repeated measurements of VOCs and the concentration of phytoncides before intervention and one week later after placing potted plants into indoor environments (living room and bedroom).
In conclusion, this study aims to investigate the clinical utility of potted mint plants in reducing indoor bacterial and fungal growth and indoor air pollution, and cardiovascular benefits. Furthermore, the possible application of indoor potted mint plant in antiviral influenza or pneumonia in the future.
Detailed description
The contribution of air pollution is a very important public health issue for human health. Indoor air quality may have more influence on human health than outdoor air pollution. Previous studies indicate indoor air pollution which causes respiratory disease has been associated with cardiovascular disease. Besides, some studies showed that indoor CO2 concentration was positively correlated with virus detection and bacterial concentration in the air, and coagulase-negative staphylococci (CNS) was detected in many poorly ventilated indoor environments. Mint can release chemical substance to inhibit viruses and bacteria. Among the components, the menthol and terpineol induced vasodilation so as to reduce blood pressure. For the pilot study we have finished the qualitative and quantitative research in chemical components released by the mint.
Therefore, this study aims to evaluate the indoor air quality and the distribution of fungal and bacterial concentration in the indoor environment, analyze the effect of potted mint plants on indoor air quality, fungal and bacterial concentration, and explore the correlation between the intervention of potted mint plants and cardiovascular health.
This study will recruit 60 subjects, in sum of 30 families. We will measure 2 indoor environments (living room and bedroom) for All-in-one monitoring the indoor air quality, in which collected culturable fungus and bacteria indoor to calculate colony forming unit (CFU). We will apply Kore Technology (MS-200) (Electron Ionization time-of-flight mass spectrometry, EI-TOF-MS) to measure the indoor volatile organic chemicals (VOCs) before intervention and perform repeated measurements of VOCs and the concentration of phytoncides before intervention and one week later after placing potted plants into indoor environments (living room and bedroom).
Furthermore, we used matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) to identify microbiology; simultaneously, we record the outdoor environment and indoor ventilation. To assess subjects' cardiovascular health, we use DynaPulse to evaluate their cardiovascular function, and make them equipped with Holter electrocardiography (ECG) to continuously monitor the trend of heart rate variability (HRV) before and after intervention.
In conclusion, this study aims to investigate the clinical utility of potted mint plants in reducing indoor bacterial and fungal growth and indoor air pollution, and cardiovascular benefits. Furthermore, the possible application of indoor potted mint plant in antiviral influenza or pneumonia in the future.
Study design
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- This study will recruit 60 subjects, in sum of 30 families.
| Arm | Type | Receives |
|---|---|---|
| Potted Mint Plants Intervention | Other | Other: Potted Mint PlantsWe will measure 2 indoor environments (living room and bedroom) for placing potted plants. We will analyze the effect of potted mint plants on indoor air quality, fungal and bacterial concentration, and explore the correlation between the intervention of potted mint plants and cardiovascular health. |
Who may qualify
- Ages
- 20 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- in the Department of Cardiology or inpatients at National Taiwan University Hospital
- aged 20-80
- live in the Greater Taipei area
Key exclusion criteria (3 listed)
- The research subjects must agree to cooperate with the health assessment.
- serious brain, heart disease and mental illness
- uncomfortable reactions
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Potted Mint PlantsWe will measure 2 indoor environments (living room and bedroom) for placing potted plants. | Other | Potted Mint Plants Intervention |
Primary outcome
Improve Indoor Air Quality
Time frame: one week
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Dec 2020.
- Individual participant dataSharing planned: Undecided
Related trials for Cardiovascular Diseases
Recruiting
Reducing Slow/No-Reflow With Prophylactic High-Dose Intracoronary Adenosine Protocol in ST-Elevation Myocardial Infarction The REFLOW AMI Trial
ST-Elevation Myocardial Infarction (STEMI)
RecruitingPhase 3
A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
Multiple Myeloma
Active, not recruitingObservational study
EFFECT OF HYBRID CLOSED-LOOP SYSTEMS ON CARDIOVASCULAR MARKERS IN TYPE 1 DIABETES.
Type 1 Diabetes
RecruitingPhase 4
Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
Hypertensive Disorders of Pregnancy, Preeclampsia
Active, not recruiting
Insulin Resistance and Coronary Microvascular Dysfunction in Patients With Myocardial Ischemia and Non-obstructive Coronary Artery Disease
Coronary Microvascular Dysfunction, Coronary Microvascular Disease
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Su ta chen, PI principal investigator
NTUH
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Potted Mint Plants in people with Cardiovascular Diseases, run by National Taiwan University Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 1 Dec 2020. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Improve Indoor Air Quality (time frame: one week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Dec 2020.