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DementiaNCT04589637

Factors Influencing the Deterioration From Cognitive Decline of Normal Aging to Dementia Among Nursing Home Residents

An observational study of Dementia, run by Jordan University of Science and Technology at 1 site in Jordan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Background: A dearth of differential research exists regarding the determinants of mild cognitive impairment (MCI) and moderate cognitive impairment or dementia among nursing home residents. Read more about this study

Who is it for?
Ages 60 to 85 years
Conditions the study is for
Dementia
How many people
182 participants
Where
1 siteJordan
Study dates
29 May 2018to 16 May 2019
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 60 to 85 years
  • All sexes
  • Adult, Older adult

Study population: Convenience sampling of 182 participants was used to obtain moderate size correlation (r = 0.35), given a power of 0.80, two-sided Type I error rate of p = 0.0167, based on nQuery calculation [16]. The participants were recruited from 5 holistic nursing homes, including private and public nursing homes, located in the center of Jordan. Inclusion criteria were as follows: Jordanian participants, aged 60 years and older, and living in nursing homes. Exclusion criteria were neurological disorders, such as stroke or brain injury.

Who may be able to join

  • Jordanian participants, aged 60 years and older, and living in nursing homes

Who cannot join

  • neurological disorders, such as stroke or brain injury

Trial locations and contacts

1 site in 1 country.

Jordan1 site

  • Nursing homes

    Amman

Other trials in Jordan

About this study

Background: A dearth of differential research exists regarding the determinants of mild cognitive impairment (MCI) and moderate cognitive impairment or dementia among nursing home residents. This study aimed to identify and examine the association between medical factors (number of comorbidities, hospitalization, disability, depression, frailty and quality of life) and moderate cognitive impairment or dementia in nursing homes residents.

Methods: A cross-sectional design was used in this study. Convenience sampling of 182 participants was conducted in nursing homes located in the central part of Jordan. Montreal cognitive assessment (MoCA) was used to screen both MCI and moderate cognitive impairment or dementia. Bivariate analysis, including t-test and ANOVA test, and logistic and linear regression models were used to examine and identify the medical factors associated with moderate cognitive impairment or dementia compared to mild cognitive impairment.

Conditions
Dementia
Medical subject headings
Dementia

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. moderate cognitive impairment

    Measured: May, 2018-May, 2019

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted19 Oct 2020
  2. Study start29 May 2018
  3. Primary completion1 Dec 2018
  4. Study completion16 May 2019

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Cross-sectional
Enrolment
182 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT04589637
Sponsor's protocol ID
JUST20180229
Status last verified
Oct 2020
First submitted
13 Oct 2020
Last updated
19 Oct 2020
Results posted
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Kijowska V, Szczerbinska K. Prevalence of cognitive impairment among long-term care residents: a comparison between nursing homes and residential homes in Poland. Eur Geriatr Med. 2018 Aug;9(4):467-476. doi: 10.1007/s41999-018-0062-2. Epub 2018 May 16.

    PubMed 34674486

  • Hayajneh, A.A. , Ivanov, L.L. & Rababa, M. (2019). Jordanian Nursing Homes: Admission Policy Analysis. Global Journal of Health Science, 11 (6), 118-122.

  • Janet D. Elashoff. nQuery Advisor Version 7.0 [software]. 2007: User's Guide. Los Angeles, CA

  • The Montreal Cognitive Assessment (MoCA). What are the severity levels for the MoCA?. : Copyright 2019 Ziad Nasreddine MD. All rights reserved. Available from:: https://www.mocatest.org/faq/ [30August2020]

  • Greenberg, S. Try this: the Geriatric Depression Scale (GDS). 2012: 4. The Hartford Institute for Geriatric Nursing, New York University, College of Nursing.

  • Hayajneh, A. A. The Psychometric Properties of the Arabic Version of the Tilburg Frailty Indicator. Global Journal of Health Science. 2019: 11(9), 123-133. doi:10.5539/gjhs.v11n9p123

  • Al-btoush, A. Relation between the Psychological Impact of Presbycusis and Hearing Handicap Inventory for the Elderly Using Screening Version in Jordan. Middle East Journal of Age and Ageing. 2012: 9(5), 23-25.

  • Abdelmoneium, A.O. & Alharahsheh, S.T. Family Home Caregivers for Old Persons in the Arab Region: Perceived Challenges and Policy Implications. Open Journal of Social Sciences. 2016: 4, 151-164. http://dx.doi.org/10.4236/jss.2016.41019

  • Arafa, Mohamed A., What's New in the Residential Care of the Elderly in the Arab and Islamic World? The Case of Egypt. Towards Human Rights in Residential Care for Older Persons: International Perspectives. 2015: (Chapter 2, Routledge, London & New York), Available at SSRN: https://ssrn.com/abstract=2710357

  • Atif, M., Saleem, Q. & Scahill, S. Depression and mild cognitive impairment (MCI) among elderly patients with type 2 diabetes mellitus in Pakistan: possible determinants. Int J Diabetes Dev Ctries. 2018: 38, 312-320. https://doi.org/10.1007/s13410-017-0600-3

  • Elliott, I. Poverty and Mental Health: A review to inform the Joseph Rowntree Foundation's Anti-Poverty Strategy. 2016: London: Mental Health Foundation.

  • Mosti C.B., Rog L.A., Fink J.W. Differentiating Mild Cognitive Impairment and Cognitive Changes of Normal Aging. In: Ravdin L., Katzen H. (eds) Handbook on the Neuropsychology of Aging and Dementia. Clinical Handbooks in Neuropsychology. 2019. Springer, Cham

  • Langa KM, Levine DA. The diagnosis and management of mild cognitive impairment: a clinical review. JAMA. 2014 Dec 17;312(23):2551-61. doi: 10.1001/jama.2014.13806.

    PubMed 25514304

  • Qarni T, Salardini A. A Multifactor Approach to Mild Cognitive Impairment. Semin Neurol. 2019 Apr;39(2):179-187. doi: 10.1055/s-0039-1678585. Epub 2019 Mar 29.

    PubMed 30925611

  • Ferreira AR, Dias CC, Fernandes L. Needs in Nursing Homes and Their Relation with Cognitive and Functional Decline, Behavioral and Psychological Symptoms. Front Aging Neurosci. 2016 Apr 21;8:72. doi: 10.3389/fnagi.2016.00072. eCollection 2016.

    PubMed 27148044

Questions about this trial

What is this clinical trial studying?

An observational study of Dementia, run by Jordan University of Science and Technology at 1 site in Jordan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 19 Oct 2020. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Jordan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

moderate cognitive impairment (time frame: May, 2018-May, 2019). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT04589637, which also lists 46 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2020.

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