MalariaUHMSNCT04622241
Uganda Housing Modification Study
A study testing Eave Tubes, Eave Ribbons and Full House Screening in people with Malaria and Anemia, run by Infectious Diseases Research Collaboration, Uganda at 1 site in Uganda.
Trial summary
To explore housing modification as a malaria control intervention, and to assess the degree to which it may offer protection in moderate to high malaria endemicity settings, we propose a two-phase study evaluating epidemiological and entomological effectiveness, cost-effectiveness, feasibility, and acceptability of… Read more about this study
- Who is it for?
- Ages Up to 14 yearsHealthy volunteers can take part
- What is being tested?
- Eave Tubes, Eave Ribbons and Full House Screening
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 2,422 participants
- Where
- 1 siteUganda
- Study dates
- 29 Jan 2021to Jul 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Up to 14 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
- At least one adult aged 18 years or older present
- Agreement of the adult resident to provide informed consent for the pilot study
- Phase II
- Cohort Study
- Household considered their primary residence
- Child aged less than 59 months
Show all 21Show fewer
- Agreement to come to the study clinic for any febrile illness
- Agreement to avoid antimalarial medications outside the study
- Provision of written informed consent (for parent or guardian in case of children)
- Cross-sectional Community Survey - Household Survey
- At least one household resident between 6 months and 14 years of age present (with an adult caregiver willing to provide informed consent for the clinical survey)
- At least one adult aged 18 years or older present
- Adult is a usual resident who slept in the sampled household on the night before the survey
- Agreement of the adult resident to provide informed consent for the household survey
- Child aged 6 months to 14 years
- Usual resident who was present in the sampled household on the night before the survey
- Agreement of parent/guardian to provide informed consent
- Agreement of child aged 8 years or older to provide assent
- Willingness to take chemoprophylaxis for malaria
- Willingness to abstain from alcohol during working hours
- No significant past medical history.
Who cannot join
- Dwelling destroyed or not found
- Household vacant
- No adult resident home on more than 3 occasions
- Cross-sectional Community Survey - Clinical Survey
- Child not home on day of survey
- Recruitment of Field Workers for entomology activities (human landing catches).
Trial locations and contacts
1 site in 1 country.
Uganda1 site
Infectious Diseases Research Collaboration
Kampala, Central Region
About this study
Official title: Impact of Housing Modifications Combined With Piperonyl Butoxide (PBO) Long-lasting Insecticidal Nets (LLINs) on the Malaria Burden in Uganda: a Cluster-randomised Trial
To explore housing modification as a malaria control intervention, and to assess the degree to which it may offer protection in moderate to high malaria endemicity settings, we propose a two-phase study evaluating epidemiological and entomological effectiveness, cost-effectiveness, feasibility, and acceptability of housing modification in Uganda. The first phase will be a pilot implementation assessing the feasibility of candidate housing modification interventions, followed by a cluster randomised control trial of the most effective, scalable, and cost-effective interventions.
Read the detailed description
The study will be conducted in two phases, beginning with a pilot (Phase I). The aim of the pilot will be to develop and test four types of housing modifications in both modern houses (those with brick or stone walls) and traditionally constructed houses (those with mud walls). The housing modifications will include: (1) full house screening (eaves and windows), (2) partial house screening (eaves or ceiling), (3) eave tubes, and (4) eave ribbons. Community input will be sought during the development of the housing prototypes.
In the pilot, all 4 interventions will be implemented in both modern and traditional houses, plus a control arm in each group. All households will have access to PBO LLINs. Community input will be sought during the development of the housing prototypes. The pilot will include 10 arms in total, each consisting of 20 households, equal to 200 households (160 in the intervention and 40 in the control arm) in total. The feasibility and effectiveness of the interventions will be assessed through a qualitative study (FGDs and interviews), evaluation of the costs and implementation of the interventions, and entomology surveys (using CDC light traps). One to two housing interventions will be selected for Phase II following the review and discussion of the pilot results with the trial steering committee.
Phase II will include a cluster-randomised trial. A cluster will be defined as a village (or segment of a village consisting of ~100 households). In the cluster-randomised trial, up to 2 interventions vs 1 control arm will be assessed in 20 clusters per arm (60 clusters total). The clusters will be non-contiguous, with a buffer zone of 300-500m. All households in the selected clusters will have PBO LLINs; households in intervention clusters will also receive the specified housing modifications. The impact of the interventions will be assessed through a cohort study, cross-sectional community surveys, entomology surveillance, a qualitative study, and an economic evaluation. The primary outcome of the trial will be clinical malaria incidence in children aged < 60 months as measured in the cohort study.
- Being tested
- Eave Tubes, Eave Ribbons, Full House Screening, Partial House Screening
- Keywords
- Housing Modification, Vector Control, Uganda, Malaria Control
- Medical subject headings
- Malaria, Anemia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Eave TubesOther
The eave tubes are PVC tubes with a diameter of 15 cm installed in the outer wall of occupied rooms (e.g. bedrooms and living rooms but not storage rooms) at 1.5-2 m intervals, fitted with electrostatic mesh inserts coated with insecticides. No additional screening will be done. All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents.
Eave RibbonsOther
Eave ribbons are 15 cm-wide triple-layered hessian fabrics (burlap-line fabric woven from sisal fibres, procured locally), in lengths starting 1 m that can be attached to houses using nails, adhesives or Velcro, without completely closing eave-spaces. The eave ribbons will be treated by study staff with a commonly used spatial repellent, transfluthrin. Eave ribbons will be retreated by study staff after 6 months (only in Phase II, if selected for inclusion in the cluster-randomised trial).
All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents.
Full House ScreeningOther
Full house screening includes screening eaves/ceilings, ventilation openings, and windows. Eaves/ceiling, air vents, and windows of eligible houses will be screened with wire mesh or other locally available screening materials. or ceilings, if eaves are closed" and ventilation openings. We are also filling in any gaps in the walls. All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents.
Partial House ScreeningOther
Partial screening will include either screening of the eaves or installing a screened ceiling, where no ceiling is present. In traditional houses, a netting (either insecticide-impregnated or untreated) may be either fixed in multiple places in the rafters or by hanging from a single central point and attached to the walls. No other screening or filling of the gaps will be done in partially screened houses.All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents.
| Study group | Role | What they receive |
|---|---|---|
| Eave Tubes - Traditional House | Experimental | Installation of eave tubes in traditional homes. Receives: Other: Eave Tubes |
| Eave Tubes - Modern House | Experimental | Installation of eave tubes in modern homes. Receives: Other: Eave Tubes |
| Eave Ribbons - Traditional House | Experimental | Installation of eave ribbons in traditional homes. Receives: Other: Eave Ribbons |
| Eave Ribbons - Modern House | Experimental | Installation of eave ribbons in modern homes. Receives: Other: Eave Ribbons |
| Full House Screening - Traditional House | Experimental | Installation of full house screening, includes screening eaves and windows, in traditional homes. Receives: Other: Full House Screening |
| Full House Screening - Modern House | Experimental | Installation of full house screening, includes screening eaves and windows, in modern homes. Receives: Other: Full House Screening |
| Partial House Screening - Traditional House | Experimental | Installation of partial screening, includee either screening of the eaves or installing a screened ceiling, in traditional homes. Receives: Other: Partial House Screening |
| Partial House Screening - Modern House | Experimental | Installation of partial screening, includee either screening of the eaves or installing a screened ceiling, in modern homes. Receives: Other: Partial House Screening |
| Control - Traditional House | No intervention | Control group with no intervention in traditional homes |
| Control - Modern House | No intervention | Control group with no intervention in modern homes. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Incidence of malaria
Number of incident episodes of clinical malaria per time of observation. Incident episodes of malaria defined as any treatment for malaria > 14 days after any prior treatment for malaria
Measured: 12 months following housing modification
Secondary outcomes (20)
Parasite prevalence
Proportion of study participants with a thick blood smear positive for asexual parasites as measured by microscopy
Measured: 12 months following housing modification
Prevalence of anaemia
Proportion of haemoglobin measurements categorised as anaemia as per WHO age-stratified guidelines
Measured: 12 months following housing modification
Vector density
Number of female Anopheles mosquitoes captured/room per night by CDC light traps
Measured: 12 months following housing modification
Sporozoite rate
Proportion of captured female Anopheles mosquitoes that test positive for sporozoites
Measured: 12 months following housing modification
Annual entomological inoculation rate
Number of infected bites per person per year (human biting rate x sporozoite rate x 365 days/year)
Measured: 12 months following housing modification
Proportion of mosquitoes with insecticide resistance
Proportion of mosquitoes with phenotypic expression of insecticide resistance or containing genetic polymorphisms associated with resistance to insecticides of interest as identified by PCR
Measured: 12 months following housing modification
Proportion of individuals satisfied with the interventions
Indicator of acceptability
Measured: 12 months following housing modification
Proportion of households that require minimal maintenance of the implemented intervention over the period of the study, by study intervention
Indicator of durability
Measured: 12 months following housing modification
Longer term cost of the maintenance and upkeep of the implemented intervention, by study intervention
Indicator of durability
Measured: 12 months following housing modification
Costs of housing improvements, including maintenance, by improvement type
Indicator of feasibility
Measured: 12 months following housing modification
Incremental cost-effectiveness ratios (ICER) of each package
Cost per malaria case averted, Cost per DALY averted
Measured: 12 months following housing modification
Proportion of households that received the assigned housing modification
Indicator of fidelity
Measured: 12 months following housing modification
Proportion of households that received 1 PBO LLIN for every 2 residents
Indicator of fidelity
Measured: 12 months following housing modification
Proportion of households that received full/partial/no housing modifications
Dose delivered
Measured: 12 months following housing modification
Proportion of households that received adequate/inadequate/no PBO LLINs
Dose delivered
Measured: 12 months following housing modification
Proportion of households that utilized full/partial/no housing modifications
Dose received
Measured: 12 months following housing modification
Proportion of household residents that slept under a PBO LLIN the previous night
Dose received
Measured: 12 months following housing modification
Proportion of households that were fully covered by the assigned housing modification
Indicator of reach
Measured: 12 months following housing modification
Proportion of household residents that were fully covered by the PBO LLINs
Indicator of reach
Proportion of households fully covered by both the modifications \& PBO LLINs
Measured: 12 months following housing modification
Proportion of households fully covered by both the modifications & PBO LLINs
Indicator of reach
Measured: 12 months following housing modification
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Nov 2020
- Study start29 Jan 2021
- Primary completionMay 2023 (estimated)
- Study completionJul 2023 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for MalariaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Phase II will be carried out as a cluster-randomized trial with 3 arms (2 interventions selected from the pilot study, and 1 control). There will be 20 clusters per arm (60 clusters total) and a cluster will be defined as an enumeration area within a village. All participating households in the selected clusters will have PBO LLINs, and households in intervention clusters will also receive the specified housing modifications. The impact of the interventions on malaria burden will be assessed through a cohort study, cross-sectional community surveys, entomology surveillance, a qualitative study, and an economic evaluation. The primary outcome of the trial will be clinical malaria incidence in children aged \< 60 months.
- Masking
- None (open label)
- Enrolment
- 2,422 participants (actual)
Sponsor and investigators
- Lead sponsor
- Infectious Diseases Research Collaboration, Uganda
- Sponsor type
- University, hospital or other
- Collaborators
- Centers for Disease Control and Prevention, United States Agency for International Development (USAID), London School of Hygiene and Tropical Medicine, University of California, San Francisco
- Responsible party
- Sponsor
- Investigators
- Nelli Westercamp, PhD MBA, Principal investigator, Centers for Disease Control and PreventionMoses Kamya, MBChB PhD, Principal investigator, Infectious Diseases Research Collaboration
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04622241
- Sponsor's protocol ID
- 72061720FA00002
- Acronym
- UHMS
- Status last verified
- Aug 2022
- First submitted
- 4 Nov 2020
- Last updated
- 4 Aug 2022
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Snyman K, Ochieng W, Gonahasa S, Aber J, Katureebe A, Staedke SG, Kamya MR, Westercamp N, Pitt C. Housing modification to prevent malaria in Uganda: an analysis of costs, willingness to pay, and equity. Malar J. 2025 Dec 24;25(1):60. doi: 10.1186/s12936-025-05757-0.
PubMed 41444546Kayendeke M, Nabirye C, Nayiga S, Westercamp N, Gonahasa S, Katureebe A, Kamya MR, Staedke SG, Hutchinson E. House modifications as a malaria control tool: how does local context shape participants' experience and interpretation in Uganda? Malar J. 2023 Aug 25;22(1):244. doi: 10.1186/s12936-023-04669-1.
PubMed 37626312
Study at a glance
From the registry record, last updated by the sponsor on 4 Aug 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Housing Modifications Combined With Piperonyl Butoxide (PBO) Long-lasting Insecticidal Nets (LLINs) on the Malaria Burden in Uganda: a Cluster-randomised Trial
- ClinicalTrials.gov ID
- NCT04622241
- Acronym / sponsor ID
- UHMS / 72061720FA00002
- Keywords
- Housing Modification, Vector Control, Uganda, Malaria Control
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 2,422 participants (actual)
- Lead sponsor
- Infectious Diseases Research Collaboration, UgandaUniversity, hospital or other
- Collaborators
- Centers for Disease Control and Prevention, United States Agency for International Development (USAID), London School of Hygiene and Tropical Medicine, University of California, San Francisco
- Study start
- 29 Jan 2021 (actual)
- Primary completion
- May 2023 (estimated)
- Study completion
- Jul 2023 (estimated)
- First posted
- 9 Nov 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To explore housing modification as a malaria control intervention, and to assess the degree to which it may offer protection in moderate to high malaria endemicity settings, we propose a two-phase study evaluating epidemiological and entomological effectiveness, cost-effectiveness, feasibility, and acceptability of housing modification in Uganda. The first phase will be a pilot implementation assessing the feasibility of candidate housing modification interventions, followed by a cluster randomised control trial of the most effective, scalable, and cost-effective interventions.
Detailed description
The study will be conducted in two phases, beginning with a pilot (Phase I). The aim of the pilot will be to develop and test four types of housing modifications in both modern houses (those with brick or stone walls) and traditionally constructed houses (those with mud walls). The housing modifications will include: (1) full house screening (eaves and windows), (2) partial house screening (eaves or ceiling), (3) eave tubes, and (4) eave ribbons. Community input will be sought during the development of the housing prototypes.
In the pilot, all 4 interventions will be implemented in both modern and traditional houses, plus a control arm in each group. All households will have access to PBO LLINs. Community input will be sought during the development of the housing prototypes. The pilot will include 10 arms in total, each consisting of 20 households, equal to 200 households (160 in the intervention and 40 in the control arm) in total. The feasibility and effectiveness of the interventions will be assessed through a qualitative study (FGDs and interviews), evaluation of the costs and implementation of the interventions, and entomology surveys (using CDC light traps). One to two housing interventions will be selected for Phase II following the review and discussion of the pilot results with the trial steering committee.
Phase II will include a cluster-randomised trial. A cluster will be defined as a village (or segment of a village consisting of ~100 households). In the cluster-randomised trial, up to 2 interventions vs 1 control arm will be assessed in 20 clusters per arm (60 clusters total). The clusters will be non-contiguous, with a buffer zone of 300-500m. All households in the selected clusters will have PBO LLINs; households in intervention clusters will also receive the specified housing modifications. The impact of the interventions will be assessed through a cohort study, cross-sectional community surveys, entomology surveillance, a qualitative study, and an economic evaluation. The primary outcome of the trial will be clinical malaria incidence in children aged < 60 months as measured in the cohort study.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 10
- Model description
- Phase II will be carried out as a cluster-randomized trial with 3 arms (2 interventions selected from the pilot study, and 1 control). There will be 20 clusters per arm (60 clusters total) and a cluster will be defined as an enumeration area within a village. All participating households in the selected clusters will have PBO LLINs, and households in intervention clusters will also receive the specified housing modifications. The impact of the interventions on malaria burden will be assessed through a cohort study, cross-sectional community surveys, entomology surveillance, a qualitative study, and an economic evaluation. The primary outcome of the trial will be clinical malaria incidence in children aged < 60 months.
| Arm | Type | Receives |
|---|---|---|
| Eave Tubes - Traditional House | Experimental | Other: Eave TubesInstallation of eave tubes in traditional homes. |
| Eave Tubes - Modern House | Experimental | Other: Eave TubesInstallation of eave tubes in modern homes. |
| Eave Ribbons - Traditional House | Experimental | Other: Eave RibbonsInstallation of eave ribbons in traditional homes. |
| Eave Ribbons - Modern House | Experimental | Other: Eave RibbonsInstallation of eave ribbons in modern homes. |
| Full House Screening - Traditional House | Experimental | Other: Full House ScreeningInstallation of full house screening, includes screening eaves and windows, in traditional homes. |
| Full House Screening - Modern House | Experimental | Other: Full House ScreeningInstallation of full house screening, includes screening eaves and windows, in modern homes. |
| Partial House Screening - Traditional House | Experimental | Other: Partial House ScreeningInstallation of partial screening, includee either screening of the eaves or installing a screened ceiling, in traditional homes. |
| Partial House Screening - Modern House | Experimental | Other: Partial House ScreeningInstallation of partial screening, includee either screening of the eaves or installing a screened ceiling, in modern homes. |
| Control - Traditional House | No intervention | –Control group with no intervention in traditional homes |
| Control - Modern House | No intervention | –Control group with no intervention in modern homes. |
Who may qualify
- Ages
- Up to 14 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (21 listed)
- At least one adult aged 18 years or older present
- Agreement of the adult resident to provide informed consent for the pilot study
- Phase II
- Cohort Study
- Household considered their primary residence
Key exclusion criteria (6 listed)
- Dwelling destroyed or not found
- Household vacant
- No adult resident home on more than 3 occasions
- Cross-sectional Community Survey - Clinical Survey
- Child not home on day of survey
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Eave TubesThe eave tubes are PVC tubes with a diameter of 15 cm installed in the outer wall of occupied rooms (e.g. bedrooms and living rooms but not storage rooms) at 1.5-2 m intervals, fitted with electrostatic mesh inserts coated with insecticides. No additional screening will be done. All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents. | Other | Eave Tubes - Modern House, Eave Tubes - Traditional House |
| Eave RibbonsEave ribbons are 15 cm-wide triple-layered hessian fabrics (burlap-line fabric woven from sisal fibres, procured locally), in lengths starting 1 m that can be attached to houses using nails, adhesives or Velcro, without completely closing eave-spaces. The eave ribbons will be treated by study staff with a commonly used spatial repellent, transfluthrin. Eave ribbons will be retreated by study staff after 6 months (only in Phase II, if selected for inclusion in the cluster-randomised trial). All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents. | Other | Eave Ribbons - Modern House, Eave Ribbons - Traditional House |
| Full House ScreeningFull house screening includes screening eaves/ceilings, ventilation openings, and windows. Eaves/ceiling, air vents, and windows of eligible houses will be screened with wire mesh or other locally available screening materials. or ceilings, if eaves are closed" and ventilation openings. We are also filling in any gaps in the walls. All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents. | Other | Full House Screening - Modern House, Full House Screening - Traditional House |
| Partial House ScreeningPartial screening will include either screening of the eaves or installing a screened ceiling, where no ceiling is present. In traditional houses, a netting (either insecticide-impregnated or untreated) may be either fixed in multiple places in the rafters or by hanging from a single central point and attached to the walls. No other screening or filling of the gaps will be done in partially screened houses.All households will be provided with piperonyl butoxide (PBO) long-lasting insecticidal nets (LLINs) - one for every two residents. | Other | Partial House Screening - Modern House, Partial House Screening - Traditional House |
Primary outcome
Incidence of malaria
Time frame: 12 months following housing modification
Number of incident episodes of clinical malaria per time of observation. Incident episodes of malaria defined as any treatment for malaria > 14 days after any prior treatment for malaria
20 secondary outcomes
Parasite prevalence
Time frame: 12 months following housing modification
Prevalence of anaemia
Time frame: 12 months following housing modification
Vector density
Time frame: 12 months following housing modification
Sporozoite rate
Time frame: 12 months following housing modification
Annual entomological inoculation rate
Time frame: 12 months following housing modification
Proportion of mosquitoes with insecticide resistance
Time frame: 12 months following housing modification
Proportion of individuals satisfied with the interventions
Time frame: 12 months following housing modification
Proportion of households that require minimal maintenance of the implemented intervention over the period of the study, by study intervention
Time frame: 12 months following housing modification
Longer term cost of the maintenance and upkeep of the implemented intervention, by study intervention
Time frame: 12 months following housing modification
Costs of housing improvements, including maintenance, by improvement type
Time frame: 12 months following housing modification
Incremental cost-effectiveness ratios (ICER) of each package
Time frame: 12 months following housing modification
Proportion of households that received the assigned housing modification
Time frame: 12 months following housing modification
Proportion of households that received 1 PBO LLIN for every 2 residents
Time frame: 12 months following housing modification
Proportion of households that received full/partial/no housing modifications
Time frame: 12 months following housing modification
Proportion of households that received adequate/inadequate/no PBO LLINs
Time frame: 12 months following housing modification
Proportion of households that utilized full/partial/no housing modifications
Time frame: 12 months following housing modification
Proportion of household residents that slept under a PBO LLIN the previous night
Time frame: 12 months following housing modification
Proportion of households that were fully covered by the assigned housing modification
Time frame: 12 months following housing modification
Proportion of household residents that were fully covered by the PBO LLINs
Time frame: 12 months following housing modification
Proportion of households fully covered by both the modifications & PBO LLINs
Time frame: 12 months following housing modification
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Aug 2022.
- Derived from this study: PubMed 41444546Snyman K, Ochieng W, Gonahasa S, Aber J, Katureebe A, Staedke SG, Kamya MR, Westercamp N, Pitt C. Housing modification to prevent malaria in Uganda: an analysis of costs, willingness to pay, and equity. Malar J. 2025 Dec 24;25(1):60. doi: 10.1186/s12936-025-05757-0.
- Derived from this study: PubMed 37626312Kayendeke M, Nabirye C, Nayiga S, Westercamp N, Gonahasa S, Katureebe A, Kamya MR, Staedke SG, Hutchinson E. House modifications as a malaria control tool: how does local context shape participants' experience and interpretation in Uganda? Malar J. 2023 Aug 25;22(1):244. doi: 10.1186/s12936-023-04669-1.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Nelli Westercamp, PhD MBA principal investigator
Centers for Disease Control and Prevention
Moses Kamya, MBChB PhD principal investigator
Infectious Diseases Research Collaboration
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Eave Tubes, Eave Ribbons and Full House Screening in people with Malaria and Anemia, run by Infectious Diseases Research Collaboration, Uganda at 1 site in Uganda.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 21 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 4 Aug 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Uganda. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incidence of malaria (time frame: 12 months following housing modification). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04622241, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Aug 2022.