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Health, SubjectiveNCT04648748

Normative Data of Hand Grip Strength in Healthy Adult Pakistani Population

An observational study of Health, Subjective, run by Riphah International University at 1 site in Pakistan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Normative data values of handgrip strength not only describes hand normality but is also used as an objective assessor of upper extremities damages for Occupational Therapy and Physical Therapy interventions. Published normative data of different populations are widely available and can be used as reference. Read more about this study

Who is it for?
Ages 20 to 70 yearsHealthy volunteers can take part
Conditions the study is for
Health, Subjective
How many people
1,500 participants
Where
1 sitePakistan
Study dates
10 Nov 2020to 1 Mar 2021
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 to 70 years
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Study population: Volunteers will be recruited from the staff, medical students, and visitors of different medical college \& universities of Lahore. Subjects will be excluded if they had a history of upper-limb injury or deformity, or related health conditions. Socioeconomic background, general health, and lifestyle of the subjects will be assessed using a standard questionnaire. Weight, height \& APM thickness will be measured prior to testing.

Who may be able to join

  • Healthy Subjects as measured on Subjective Global Assessment Form

Who cannot join

  • History/o upper limb surgery, deformity or related health condition
  • No previous history pf participation in gym activities for last 06 months

Trial locations and contacts

1 site in 1 country.

Pakistan1 site

  • Riphah International University

    Lahore, Punjab Province, 54000

Other trials in Pakistan

About this study

Normative data values of handgrip strength not only describes hand normality but is also used as an objective assessor of upper extremities damages for Occupational Therapy and Physical Therapy interventions. Published normative data of different populations are widely available and can be used as reference. It is evident from different researches that various anthropometric variables such as age, gender, ethnicity, nutritional status, shoulder circumference \& Body Mass Index(BMI), type of occupation and hand dominance of any population influence the hand muscles grip strength. Whereas, some literature shows disparity over the correlation between hand grip strength and BMI, several researchers claiming a positive relationship between BMI and grip strength in all ages of both genders, while other indicates no relationship.

Approximately 3000 volunteers will be recruited from the staff, medical students, and visitors of different medical college \& universities of Lahore. Subjects will be excluded if they had a history of upper-limb injury or deformity, or related health conditions. Socioeconomic background, general health, and lifestyle of the subjects will be assessed using a standard questionnaire. Weight, height \& APM thickness will be measured prior to testing. Correlation between Hand Grip Strength and age, weight, height, body mass index (BMI), and Adductor Polices Muscle Thickness (APMT) will be measured. Multiple linear regression analysis will be used to adjust for the effects of other variables and to identify those independently associated with Hand grip strength. All the analysis will be carried out on SPSS v 25.

Read the detailed description

In the last 20 years, a number of scientific publications from around the world point to hospital malnutrition as a direct cause for higher morbidity (slower wound healing; higher hospital infection rates; longer stay, especially among intensive care patients; higher readmission rates) and mortality. The obvious impact of such a scenario include avoidable deaths, additional costs for the social security system, and the social onus related to loss of working days.

A wide variety of methods are available for nutritional evaluation. Not with standing, none of these can currently be considered as a ''gold-standard'' for diagnosing hospital malnutrition. Available methods include anthropometry, the creatinine height index, albumin, pre-albumin, immuno competence evaluation, cholesterol, and the prognostic nutritional index, among others. However, none of these methods provides a functional evaluation of malnutrition. SGA is a well-accepted method of nutritional assessment that addresses functional status as a complement of its medical history, but it was not developed to be used to evaluate responsiveness, and so, its rating are not expected to show any modification after nutritional interventions in short periods of time.

There is evidence that muscular function is altered and muscular strength diminished, in the presence of malnutrition. According to Jeejeebhoy, malnutrition-related muscular function alterations appear before changes in anthropometric and laboratory parameters. Nevertheless, methods for evaluating muscular strength during nutritional evaluation are still scarce. The earliest nutritional alterations occur within muscle cells, and have an effect on muscle cell function. Measuring muscular strength may therefore provide a sensitive method for nutritional evaluation. Muscular loss is inevitable during malnutrition, and if untreated, may become progressive. Therefore, in addition to their ability to detect early alterations related to malnutrition, muscular function tests could also prove useful for evaluating nutritional recovery, underscoring the importance of such evaluation in this context.

Recent studies have demonstrated the validity of using hand dynamometers as a method for nutritional evaluation, given that this is a simple, fast, useful, inexpensive, and efficacious test for muscular function. Knowledge of reference values in a healthy population would allow a functional muscle evaluation not only in hospital and research settings, but also in population-based studies. The aim of the study is to determine reference values and associated factors for hand grip strength in healthy individuals.

Keywords
Hand Grip Strength, Normative Data, Healthy Adults

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Hand Grip Strength

    Hand grip strength can be quantified by measuring the amount of static force that the hand can squeeze around a dynamometer. The force has most commonly been measured in kilograms and pounds, but also in millilitres of mercury and in Newtons

    Measured: 3 Weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted1 Dec 2020
  2. Study start10 Nov 2020
  3. Primary completion1 Mar 2021
  4. Study completion1 Mar 2021

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Ecologic or community
Time perspective
Cross-sectional
Enrolment
1,500 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT04648748
Sponsor's protocol ID
REC/19/1005 Danish Hassan
Status last verified
Apr 2021
First submitted
15 Nov 2020
Last updated
13 Apr 2021
Results posted
No
Data monitoring committee
No
Individual data sharing
No

Publications

  • Lam NW, Goh HT, Kamaruzzaman SB, Chin AV, Poi PJ, Tan MP. Normative data for hand grip strength and key pinch strength, stratified by age and gender for a multiethnic Asian population. Singapore Med J. 2016 Oct;57(10):578-584. doi: 10.11622/smedj.2015164. Epub 2015 Nov 13.

    PubMed 26768064

  • Lim SH, Kim YH, Lee JS. Normative Data on Grip Strength in a Population-Based Study with Adjusting Confounding Factors: Sixth Korea National Health and Nutrition Examination Survey (2014-2015). Int J Environ Res Public Health. 2019 Jun 25;16(12):2235. doi: 10.3390/ijerph16122235.

    PubMed 31242569

  • Angst F, Drerup S, Werle S, Herren DB, Simmen BR, Goldhahn J. Prediction of grip and key pinch strength in 978 healthy subjects. BMC Musculoskelet Disord. 2010 May 19;11:94. doi: 10.1186/1471-2474-11-94.

    PubMed 20482832

  • Dodds RM, Syddall HE, Cooper R, Benzeval M, Deary IJ, Dennison EM, Der G, Gale CR, Inskip HM, Jagger C, Kirkwood TB, Lawlor DA, Robinson SM, Starr JM, Steptoe A, Tilling K, Kuh D, Cooper C, Sayer AA. Grip strength across the life course: normative data from twelve British studies. PLoS One. 2014 Dec 4;9(12):e113637. doi: 10.1371/journal.pone.0113637. eCollection 2014.

    PubMed 25474696

  • Shim JH, Roh SY, Kim JS, Lee DC, Ki SH, Yang JW, Jeon MK, Lee SM. Normative measurements of grip and pinch strengths of 21st century korean population. Arch Plast Surg. 2013 Jan;40(1):52-6. doi: 10.5999/aps.2013.40.1.52. Epub 2013 Jan 14.

    PubMed 23362480

Questions about this trial

What is this clinical trial studying?

An observational study of Health, Subjective, run by Riphah International University at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 13 Apr 2021. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Hand Grip Strength (time frame: 3 Weeks). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT04648748, which also lists 5 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Apr 2021.

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