Quadratus Lumborum BlockQLBNCT04670224
Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery
A study testing QLB anesthesia and Intravenous anesthesia without QLB in people with Quadratus Lumborum Block and Abdominoplasty, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
Trial summary
Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery. Surgery is potentially associated with a number of postoperative complications, whether cardiovascular, respiratory, infectious, thromboembolic, or digestive … Although they do not… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Quadratus Lumborum Block, Abdominoplasty, Analgesia
- What is being tested?
- QLB anesthesia and Intravenous anesthesia without QLB
- Type of treatment
- Injection or infusion
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 286 participants
- Where
- 1 siteFrance
- Study dates
- 16 Mar 2021to Jan 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adult patients admitted for programmed dermo-lipectomy surgery with or without associated liposuction.
Who cannot join
- Pregnant woman
- Patient under 18 years of age
- Subject under guardianship or curators
- Patient allergic to local anesthetics
- Infection at the puncture sites
- Patient on morphine analgesic over the long term
- Patient on antidepressants for neuropathic pain.
Trial locations and contacts
1 site in 1 country.
About this study
Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery. Surgery is potentially associated with a number of postoperative complications, whether cardiovascular, respiratory, infectious, thromboembolic, or digestive … Although they do not inevitably lead to a life-threatening prognosis, in many cases these complications delay post-operative recovery. Defined in the 1990s by Professor Henry Kehlet's Danish team, rapid rehabilitation after planned surgery is an approach to overall patient care that aims to rapidly restore previous physical and mental capacities and thus significantly reduce mortality and morbidity. Pain management is at the heart of this program and local anesthesia techniques are at the heart of early rehabilitation programs.
Described for just over a decade, Quadratus Lumborum Block (QLB) have shown their effectiveness for analgesia in abdominal, or orthopedic, or obstetrical surgery. Considering the anatomical territory concerned, this locoregional anesthesia technique seems to be very interesting in abdominoplasty to allow early rehabilitation of the patient.
- Being tested
- QLB anesthesia, Intravenous anesthesia without QLB
- Keywords
- Quadratus lumborum block, Abdominoplasty, Analgesia, Locoregional Anesthesia
- Medical subject headings
- Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
QLB anesthesiaOther
The QLB is a bilateral locoregional anesthesia technique, performed after surgery, under general anesthesia and in right and then left lateral decubitus.
Intravenous anesthesia without QLBOther
only intravenous anesthesia
| Study group | Role | What they receive |
|---|---|---|
| QLB technique | Experimental | Not described Receives: Other: QLB anesthesia |
| Intravenous anesthesia without QLB | Active comparator | Not described Receives: Other: Intravenous anesthesia without QLB |
What is being measured
The primary outcome is the main question the study is designed to answer.
Variation from baseline of morphine consumption
Measured: 24 hours after surgery
Secondary outcomes (3)
Variation from baseline of morphine consumption
Measured: 1 hour after surgery
Variation from baseline of morphine consumption
Measured: 2 hours after surgery
Variation from baseline of morphine consumption
Measured: 48 hours after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Dec 2020
- Study start16 Mar 2021
- Primary completionDec 2025 (estimated)
- Study completionJan 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Quadratus Lumborum BlockStudies of the same condition, open and under way.
- More trials run by Centre Hospitalier Universitaire, AmiensThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 286 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire, Amiens
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04670224
- Sponsor's protocol ID
- PI2020_843_0094
- Acronym
- QLB
- Status last verified
- May 2025
- First submitted
- 1 Dec 2020
- Last updated
- 29 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery
- ClinicalTrials.gov ID
- NCT04670224
- Acronym / sponsor ID
- QLB / PI2020_843_0094
- Keywords
- Quadratus lumborum block, Abdominoplasty, Analgesia, Locoregional Anesthesia
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 286 participants (estimated)
- Lead sponsor
- Centre Hospitalier Universitaire, AmiensUniversity, hospital or other
- Study start
- 16 Mar 2021 (actual)
- Primary completion
- Dec 2025 (estimated)
- Study completion
- Jan 2026 (estimated)
- First posted
- 17 Dec 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery. Surgery is potentially associated with a number of postoperative complications, whether cardiovascular, respiratory, infectious, thromboembolic, or digestive … Although they do not inevitably lead to a life-threatening prognosis, in many cases these complications delay post-operative recovery. Defined in the 1990s by Professor Henry Kehlet's Danish team, rapid rehabilitation after planned surgery is an approach to overall patient care that aims to rapidly restore previous physical and mental capacities and thus significantly reduce mortality and morbidity. Pain management is at the heart of this program and local anesthesia techniques are at the heart of early rehabilitation programs.
Described for just over a decade, Quadratus Lumborum Block (QLB) have shown their effectiveness for analgesia in abdominal, or orthopedic, or obstetrical surgery. Considering the anatomical territory concerned, this locoregional anesthesia technique seems to be very interesting in abdominoplasty to allow early rehabilitation of the patient.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| QLB technique | Experimental | Other: QLB anesthesia |
| Intravenous anesthesia without QLB | Active comparator | Other: Intravenous anesthesia without QLB |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Adult patients admitted for programmed dermo-lipectomy surgery with or without associated liposuction.
Key exclusion criteria (7 listed)
- Pregnant woman
- Patient under 18 years of age
- Subject under guardianship or curators
- Patient allergic to local anesthetics
- Infection at the puncture sites
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| QLB anesthesiaThe QLB is a bilateral locoregional anesthesia technique, performed after surgery, under general anesthesia and in right and then left lateral decubitus. | Other | QLB technique |
| Intravenous anesthesia without QLBonly intravenous anesthesia | Other | Intravenous anesthesia without QLB |
Primary outcome
Variation from baseline of morphine consumption
Time frame: 24 hours after surgery
3 secondary outcomes
Variation from baseline of morphine consumption
Time frame: 1 hour after surgery
Variation from baseline of morphine consumption
Time frame: 2 hours after surgery
Variation from baseline of morphine consumption
Time frame: 48 hours after surgery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 May 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing QLB anesthesia and Intravenous anesthesia without QLB in people with Quadratus Lumborum Block and Abdominoplasty, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 29 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Variation from baseline of morphine consumption (time frame: 24 hours after surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 May 2025.