ElectromyographyNCT04706169
Age-related Differences in Shoulder Dynamic and Isometric Contractions
An observational study of Electromyography, run by University of Castilla-La Mancha.
Trial summary
A cross-sectional descriptive study, in which the surface electromyographic activity of five shoulder muscles was compared in two populations: older adults and adults. The evaluation of the electromyographic data offers a suitable foundation to understand aging process. Read more about this study
- Who is it for?
- Ages 20 years and olderHealthy volunteers can take part
- Conditions the study is for
- Electromyography
- What is being tested?
- Surface Electromyography
- Type of treatment
- Medical device
- How many people
- 60 participants
- Where
- No sites listed yet
- Study dates
- Dec 2015to Mar 2019
- How long will I take part?
- 2 Days
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Participants came from Madrid and Castilla La Mancha (Spain) and voluntarily attended the Unit of the Research Group "Physical Therapy in Women´s Health Processes" in the Department of Physical Therapy, University of Alcalá, and the Ocaña Senior Center.
Who may be able to join
- Healthy subjects
- No previously manifested symptoms in the shoulder joint and/or the neck during the past year,
Who cannot join
- Moderate or severe cognitive impairment
- Rheumatologic diseases
- Massive osteoarthritis
- Tumors
- Shoulder joint instability
- Circulatory disorders (hemophilia clotting problems)
- Dermatological problems exacerbated by contact with skin.
About this study
Official title: Age-related Differences in Motor Recruitment Patterns of the Shoulder in Dynamic and Isometric Contractions. A Cross-sectional Study
A cross-sectional descriptive study, in which the surface electromyographic activity of five shoulder muscles was compared in two populations: older adults and adults. The evaluation of the electromyographic data offers a suitable foundation to understand aging process.
This supports that surface electromyography provide information about the aged shoulder muscles. Loss of functionality is suffered by a high percentage of older adults, which greatly limits their physical activity. In this sense, this paper presents findings that might be related with possible therapeutic approaches in subsequent studies.
Read the detailed description
Aging processes in the musculoskeletal system lead to functional impairments that restrict participation. Purpose: To assess differences in force and motor recruitment patterns of shoulder muscles between age groups to understand functional disorders. A cross-sectional study comparing thirty adults (20-64) and 30 older adults (>65). Surface-electromyography (sEMG) of the middle deltoid, upper and lower trapezius, infraspinatus and serratus anterior muscles was recorded. Maximum isometric voluntary contraction (MIVC) was determined at 45° glenohumeral abduction. For the sEMG signal registration, concentric and excentric contraction with and without 1 kg and isometric contraction were requested. Participants abducted the arm from 0° up to an abduction angle of 135° for concentric and excentric contraction; and from 0º to 45º and remained there at 80% of the MIVC level while isometrically pushing against a handheld dynamometer. Differences in sEMG amplitudes (root mean square, RMS) of all contractions, but also onset latencies during concentric contraction of each muscle between age groups were analyzed. Statistical differences in strength (Adults>Older adults;0.05) existed between groups. No significant differences in RMS values of dynamic contractions were detected, except for serratus anterior, but there were for isometric contraction of all muscles analyzed (Adults>Older adults;0.05). The recruitment order varied between age groups, showing a general tendency towards delayed onset times in Older Adults, except for the upper trapezius muscle. Age differences in muscle recruitment patterns were found, which underscores the importance of developing musculoskeletal data to prevent and guide geriatric shoulder pathologies.
- Conditions
- Electromyography
- Being tested
- Surface Electromyography
- Keywords
- Age groups, Shoulder muscles, Musculoskeletal diseases
- Medical subject headings
- Musculoskeletal Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Surface ElectromyographyDevice
SEMG was used to measure the amplitude and onset of five shoulder muscle electrical signal, performing glenohumeral abduction. In this movement, the middle deltoid muscle was selected because it is a main motor. The infraspinatus muscle represented the rotator cuff muscle group. The middle deltoid muscle was selected as the representative of shoulder abduction because it is a main motor in this movement. The trapezius muscle and the serratus anterior muscle were chosen as representative established of the ascending scapular rotator muscles.
| Study group | Role | What they receive |
|---|---|---|
| Older adults | Participants, without symptoms in the shoulder and / or cervical area (at least the last year), were assigned to the Older adult group: over 65 years. Receives: Device: Surface Electromyography | |
| Adults | Participants, without symptoms in the shoulder and / or cervical area (at least the last year), were assigned to the Adult groups: 20 to 64 years. Receives: Device: Surface Electromyography |
What is being measured
The primary outcome is the main question the study is designed to answer.
The mean Root Mean Square (RMS) value
The electromyographic data were captured simultaneously on a computer by using the LabChart® software. Within the time interval from 2 to 4 seconds after contraction initiation a power spectrum analysis was performed together with the determination of RMS values. The mean RMS values were automatically obtained from the software.
Measured: day 1
onset muscle contraction
The onset was obtained as the time distance of the interception between the level of pre-activation relative to the onset of arm displacement during dynamic contraction and the linearly interpolated RMS slope
Measured: day 1
Secondary outcomes (2)
Maximal isometric voluntary contraction
Using hand-held dynamometer
Measured: day 1
body mass index
is a measure of body fat based on height and weight that applies to adult men and women. Enter your weight and height using standard or metric measures.
Measured: day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Jan 2021
- Study startDec 2015
- Primary completionJan 2019
- Study completionMar 2019
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for ElectromyographyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 60 participants (actual)
- Target duration
- 2 Days
Sponsor and investigators
- Lead sponsor
- University of Castilla-La Mancha
- Sponsor type
- University, hospital or other
- Collaborators
- University of Alcala
- Responsible party
- Principal investigator, Cristina Lirio, University of Castilla-La Mancha
- Investigators
- Cristina Lirio-Romero, PhD, Principal investigator, University of Castilla-La Mancha
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04706169
- Sponsor's protocol ID
- CLirio04
- Status last verified
- Aug 2021
- First submitted
- 9 Jan 2021
- Last updated
- 11 Aug 2021
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Lirio-Romero C, Anders C, De La Villa-Polo P, Torres-Lacomba M. Implications on older women of age- and sex-related differences in activation patterns of shoulder muscles: A cross-sectional study. J Women Aging. 2019 Nov-Dec;31(6):492-512. doi: 10.1080/08952841.2018.1521654. Epub 2018 Sep 25.
PubMed 30252611McManus L, De Vito G, Lowery MM. Analysis and Biophysics of Surface EMG for Physiotherapists and Kinesiologists: Toward a Common Language With Rehabilitation Engineers. Front Neurol. 2020 Oct 15;11:576729. doi: 10.3389/fneur.2020.576729. eCollection 2020.
PubMed 33178118Medved V, Medved S, Kovac I. Critical Appraisal of Surface Electromyography (sEMG) as a Taught Subject and Clinical Tool in Medicine and Kinesiology. Front Neurol. 2020 Oct 26;11:560363. doi: 10.3389/fneur.2020.560363. eCollection 2020.
PubMed 33192993
Study at a glance
From the registry record, last updated by the sponsor on 11 Aug 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Age-related Differences in Motor Recruitment Patterns of the Shoulder in Dynamic and Isometric Contractions. A Cross-sectional Study
- ClinicalTrials.gov ID
- NCT04706169
- Acronym / sponsor ID
- CLirio04
- Conditions
- Electromyography
- Keywords
- Age groups, Shoulder muscles, Musculoskeletal diseases
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- University of Castilla-La ManchaUniversity, hospital or other
- Collaborators
- University of Alcala
- Study start
- Dec 2015
- Primary completion
- Jan 2019 (actual)
- Study completion
- Mar 2019 (actual)
- First posted
- 12 Jan 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A cross-sectional descriptive study, in which the surface electromyographic activity of five shoulder muscles was compared in two populations: older adults and adults. The evaluation of the electromyographic data offers a suitable foundation to understand aging process.
This supports that surface electromyography provide information about the aged shoulder muscles. Loss of functionality is suffered by a high percentage of older adults, which greatly limits their physical activity. In this sense, this paper presents findings that might be related with possible therapeutic approaches in subsequent studies.
Detailed description
Aging processes in the musculoskeletal system lead to functional impairments that restrict participation. Purpose: To assess differences in force and motor recruitment patterns of shoulder muscles between age groups to understand functional disorders. A cross-sectional study comparing thirty adults (20-64) and 30 older adults (>65). Surface-electromyography (sEMG) of the middle deltoid, upper and lower trapezius, infraspinatus and serratus anterior muscles was recorded. Maximum isometric voluntary contraction (MIVC) was determined at 45° glenohumeral abduction. For the sEMG signal registration, concentric and excentric contraction with and without 1 kg and isometric contraction were requested. Participants abducted the arm from 0° up to an abduction angle of 135° for concentric and excentric contraction; and from 0º to 45º and remained there at 80% of the MIVC level while isometrically pushing against a handheld dynamometer. Differences in sEMG amplitudes (root mean square, RMS) of all contractions, but also onset latencies during concentric contraction of each muscle between age groups were analyzed. Statistical differences in strength (Adults>Older adults;0.05) existed between groups. No significant differences in RMS values of dynamic contractions were detected, except for serratus anterior, but there were for isometric contraction of all muscles analyzed (Adults>Older adults;0.05). The recruitment order varied between age groups, showing a general tendency towards delayed onset times in Older Adults, except for the upper trapezius muscle. Age differences in muscle recruitment patterns were found, which underscores the importance of developing musculoskeletal data to prevent and guide geriatric shoulder pathologies.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Target follow-up
- 2 Days
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Older adults | – | Device: Surface ElectromyographyParticipants, without symptoms in the shoulder and / or cervical area (at least the last year), were assigned to the Older adult group: over 65 years. |
| Adults | – | Device: Surface ElectromyographyParticipants, without symptoms in the shoulder and / or cervical area (at least the last year), were assigned to the Adult groups: 20 to 64 years. |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Participants came from Madrid and Castilla La Mancha (Spain) and voluntarily attended the Unit of the Research Group "Physical Therapy in Women´s Health Processes" in the Department of Physical Therapy, University of Alcalá, and the Ocaña Senior Center.
Key inclusion criteria (2 listed)
- Healthy subjects
- No previously manifested symptoms in the shoulder joint and/or the neck during the past year,
Key exclusion criteria (7 listed)
- Moderate or severe cognitive impairment
- Rheumatologic diseases
- Massive osteoarthritis
- Tumors
- Shoulder joint instability
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Surface ElectromyographySEMG was used to measure the amplitude and onset of five shoulder muscle electrical signal, performing glenohumeral abduction. In this movement, the middle deltoid muscle was selected because it is a main motor. The infraspinatus muscle represented the rotator cuff muscle group. The middle deltoid muscle was selected as the representative of shoulder abduction because it is a main motor in this movement. The trapezius muscle and the serratus anterior muscle were chosen as representative established of the ascending scapular rotator muscles. | Device | Adults, Older adults |
Primary outcome
The mean Root Mean Square (RMS) value
Time frame: day 1
The electromyographic data were captured simultaneously on a computer by using the LabChart® software. Within the time interval from 2 to 4 seconds after contraction initiation a power spectrum analysis was performed together with the determination of RMS values. The mean RMS values were automatically obtained from the software.
onset muscle contraction
Time frame: day 1
The onset was obtained as the time distance of the interception between the level of pre-activation relative to the onset of arm displacement during dynamic contraction and the linearly interpolated RMS slope
2 secondary outcomes
Maximal isometric voluntary contraction
Time frame: day 1
body mass index
Time frame: day 1
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Aug 2021.
- Background: PubMed 30252611Lirio-Romero C, Anders C, De La Villa-Polo P, Torres-Lacomba M. Implications on older women of age- and sex-related differences in activation patterns of shoulder muscles: A cross-sectional study. J Women Aging. 2019 Nov-Dec;31(6):492-512. doi: 10.1080/08952841.2018.1521654. Epub 2018 Sep 25.
- Background: PubMed 33178118McManus L, De Vito G, Lowery MM. Analysis and Biophysics of Surface EMG for Physiotherapists and Kinesiologists: Toward a Common Language With Rehabilitation Engineers. Front Neurol. 2020 Oct 15;11:576729. doi: 10.3389/fneur.2020.576729. eCollection 2020.
- Background: PubMed 33192993Medved V, Medved S, Kovac I. Critical Appraisal of Surface Electromyography (sEMG) as a Taught Subject and Clinical Tool in Medicine and Kinesiology. Front Neurol. 2020 Oct 26;11:560363. doi: 10.3389/fneur.2020.560363. eCollection 2020.
- Individual participant dataSharing planned: No
Related trials for Electromyography
RecruitingPhase 2
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
Hospital Associated Disability, Immobility
Not yet recruiting
Endotracheal Tube Versus Transcartilage Needle Electrodes for Nerve Monitoring in Thyroid Surgery
Thyroid Diseases, Recurrent Laryngeal Nerve Injury
Not yet recruiting
"CORE Training for Musculoskeletal Health: A Study on Adaptive Exercise Protocols"
Core Muscle Weakness, Postural Control Deficit
Recruiting
Muscle Deterioration in Hospitalized Cancer Patient
Oncologic Diseases
Not yet recruiting
Surface Electromyographic Analysis of Scapular Stabilizer Muscle in Postural Hyperkyphosis
Hyperkyphosis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Cristina Lirio-Romero, PhD principal investigator
University of Castilla-La Mancha
Questions about this trial
What is this clinical trial studying?
An observational study of Electromyography, run by University of Castilla-La Mancha.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 11 Aug 2021. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The mean Root Mean Square (RMS) value (time frame: day 1). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04706169, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Aug 2021.