Muscle DamageNCT04748315
Recovery Kinetics After Speed-Εndurance Maintenance Training
A study testing SEMT(1:1) and SEMT (1:3) in people with Muscle Damage, run by University of Thessaly at 1 site in Greece.
Trial summary
The purpose of this study will be to inestigate the recovery kinetics on performance, neuromuscular fatigue and muscle microtaruma that will occur after two speed-endurance maintenance training protocols in elite male soccer players. Read more about this study
- Who is it for?
- Ages 18 to 35 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Muscle Damage
- What is being tested?
- SEMT(1:1) and SEMT (1:3)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 10 participants
- Where
- 1 siteGreece
- Study dates
- 1 Apr 2021to 31 Aug 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Aged between 18 and 35 years
- Active soccer players who participate on a competitive soccer level at least for 4 years(≥5 sessions per week ≥1 match per week)
- Free of chronic diseases
- Free of musculoskeletal injury
- Participants should be non-smokers
Who cannot join
- Musculoskeletal injury
- Chronic disease
- Use of alcohol, caffeine and any type of ergogenic supplements or medication before (≥ 6 months) and throughout the study.
Trial locations and contacts
1 site in 1 country.
Greece1 site
University o Thessaly, School of Physical Education and Sports Science
Trikala, 42100
About this study
Official title: Recovery Kinetics After Speed-Εndurance Maintenance Training (SEMT) in Elite Male Soccer Players
The purpose of this study will be to inestigate the recovery kinetics on performance, neuromuscular fatigue and muscle microtaruma that will occur after two speed-endurance maintenance training protocols in elite male soccer players. Also, this study will determine the comparison between two different speed endurance maintenance protocols in neuromuscular fatigue, muscle microtrauma indicators and performance factors. The training protocols will be differentiated in training work to rest ratio. The firts training protocol trial will comprise the work to rest ratio (1:1) and the other trial will comprise the work to rest ratio 1:3.
Read the detailed description
Speed endurance maintenance training is utilized in order to improve the repeated sprint and high speed running ability of soccer players during a soccer match. Also, speed endurance maintenance training includes soccer drills which stimulate high speed and powerful actions such as changes of directions, accelerations and decelerations. However these actions are associated with eccentric component and it is known that eccentric exercises induces muscle damage microtrauma. Thus, the aim of this study will be to investigate the recovery kinetics on performance, neuromuscular fatigue and muscle microtrauma that will occur after two speed-endurance maintenance training protocols in elite male soccer players. The speed endurance maintenance training (SEMT) sessions will be differentiated in training volume and specifically in the work to rest period. Specifically, a randomized three-trial, cross-over, repeated measures design will be applied. Elite male soccer players (aged 18-35 years) will participate in the present study. Also, it is considered necessary that the participants will not suffer from any musculoskeletal injuries that will limit their ability to perform the SEMT sessions. Also the participants will not be smokers and will not consume alcohol and ergogenic nutritional supplements before and during the study.
In the first phase all participants will sign an informed consent form after they will be informed about all benefits and risks of this study and they will sign a recent historical of musculoskeletal injury or illness form. Subsequently, fasting blood samples will be collected by venipuncture using a disposable needle (10-gauge) in order to estimate muscle damage concentration markers (CK), blood lactate and inflammation markers (WBC). After, delayed onset muscle soreness (DOMS) in the knee flexors (KF) and extensors (KE) of both limbs, body weight (BW), height and body composition (DXA method) will be measured in the lab. Completing the first phase, participants will be instructed by a dietitian how to record a 7 days diet recalls estimating that the energy intake during the trials will be the same. The counter movement jump (CMJ) will be measured 24 hour after (second phase) on a force platform using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg. During the CMJ will be measured the jump height (cm), the ground reaction force (N), the peak and mean power (W/kg), the vertical stiffness (Kvert, N/m/kg) and the peak rate of force development (RFD, N/s), while at the same time will be evaluated the change in peak and mean normalized EMG during the eccentric and concentric phases of the counter movement jump, for the vastus lateralis (VL), biceps femoris (BF), gastrocnemius (GAS), and gluteus maximus (GM) muscles. Electromyography data will be collected wirelessly at 2.000 Hz using a Myon MA-320 EMG system. The peak eccentric and concentric isokinetic torque of the knee flexors and extensors, in both limbs will be evaluated on an isokinetic dynamometer at 60°/sec. Also, the isometric peak torque of the knee extensors will be evaluated at 65o in both limbs. Also the fatigue rate during maximal voluntary isometric contraction will be estimated through the percent drop of peak torque between the first and the last three seconds of a 10-secong maximal isometric contraction. Also, the speed of 10m and 30m will be measured using light cells Chronojump system. The repeated sprint ability (RSA) (5x30m) will be measure using light cells Chronojump with 25 seconds rest in-between.
The soccer agility drill with a ball will be measured using light cells Chronojump in order to evaluate the soccer technical skills, 24 hour after. Finally, Open-circuit spirometry will be utilized for assessment of maximal oxygen consumption (VO2max) using an automated online pulmonary gas exchange system via breath-by-breath analysis during a graded exercise testing on a treadmill. The ability to recover after repeated intense exercise will be evaluated through the YO-YO Intermittent Recovery test level 2 and YO-YO Intermittent Endurance test level 2. 96 hours after, the participants are going to perform one of the two speed endurance maintenance training session randomly in the field. The SEMT(1:1) session will include 1 set, 6 repetitions per set and the work to rest ratio will be 1:1. The SEMT(1:3) session will iclude 1 set, 6 repetitions per set and the work to rest ratio will be 1:3. During the sessions will be assessed the change in Heart rate using a heart rate monitor and the field activity will be recorded using a global positiong system (GPS). The blood lactate will be evaluated immediately after each session. The DOMS indicator in the knee flexors (KF) and extensors (KE) of both limbs will be evaluated immediately after, 1h, 2h, 3h, 24h, 48h, and 72 hours after each session. The isometric peak torque of the knee extensors will be evaluated at 65° in limbs, post and at 1h, 2h and 3h, hours after each session. Also the fatigue rate during maximal voluntary isometric contraction will be estimated through the percent drop of peak torque between the first and the last three seconds of a 10-secong maximal isometric contraction.
Blood samples will be collected at 24h, 48h, and 72 hours after sessions. The counter movement jump (CMJ) will be measured immediately after the session, at 1h, 2h, 3h, at 24h, 48h and 72 hours after session on a force platform using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg. During the CMJ will be measured the jump height (cm), the ground reaction force (N), the peak and mean power (W/kg), the vertical stiffness (Kvert, N/m/kg) and the peak rate of force development (RFD, N/s), while at the same time will be evaluated the change in peak and mean normalized EMG during the eccentric and concentric phases of the counter movement jump, for the vastus lateralis (VL), biceps femoris (BF), gastrocnemius (GAS), and gluteus maximus (GM) muscles. Electromyography data will be collected wirelessly at 2.000 Hz using a Myon MA-320 EMG system. Also, the speed of 10m and 30m will be measured using light cells Chronojump system immediately after, at 24h, 48h and 72 hours after session. Finally the RSA test will be measured at 24h, 48h and 72 hours after sessions. Α 2 - week washout period will be adapted among trials. After, the participants will perform the process until they complete the trials.
- Conditions
- Muscle Damage
- Being tested
- SEMT(1:1), SEMT (1:3)
- Keywords
- muscle damage, Eccentric exercise, Speed maintenance training, Soccer, Recovery
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
SEMT(1:1)Other
Soccer trainning protocolo will be performed on an work to rest ratio 1:1 and the trainning volume will consist of 1 set and 6 repetitions per set
SEMT (1:3)Other
Soccer trainning protocolo will be performed on an work to rest ratio 1:3 and the trainning volume will consist of 1 set and 6 repetitions per set
| Study group | Role | What they receive |
|---|---|---|
| SEMT(1:1) | Experimental | Participants in this arm will perform an a speed endurance maintenance training consisted of work to rest ratio 1:1. Receives: Other: SEMT(1:1) |
| SEMPT(1:3) | Experimental | Participants in this arm will perform an a speed endurance maintenance training consisted of work to rest ratio 1:3. Receives: Other: SEMT (1:3) |
| Control | No intervention | Participants in this arm will receive no intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in white blood cell count
White blood cell count will be measured using an automatic blood analyzer
Measured: At baseline, at 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in Creatine kinase in blood
Creatine kinase will be measured in plasma
Measured: At baseline, at 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in countermovement jump height
Countermovement jump height will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Measured: At baseline, post, 1, 2,3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in ground reaction force (GRF) during countermovement jump test
The ground reaction force will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Measured: At baseline, at post, at 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in peak power during countermovement jump test
The peak power will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Measured: At baseline, post 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in mean power during countermovement jump test
The mean power will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Measured: At baseline, post, 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in vertical stifness during countermovement jump test
The vertical stifness will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Measured: At baseline, post, 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in peak rate of force development during countermovement jump test
The peak rate of force development will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Measured: At baseline, post, 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in peak normalized EMG during the eccentric and concentric phases of the countermovement jmp test
Electromyography data will be collected wirelessly at 2000Hz using a Myon MA-320 EMG system (Myon AG, Schwarzenberg, Switzerland) for the vastus lateralis (VL), biceps femoris (BF), gastrocnemius (GAS), and gluteus maximus (GM) muscles
Measured: At baseline, post, 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in mean normalized EMG during the eccentric and concentric phases of the countermovement jump test
Electromyography data will be collected wirelessly at 2000Hz using a Myon MA-320 EMG system (Myon AG, Schwarzenberg, Switzerland) for the vastus lateralis (VL), biceps femoris (BF), gastrocnemius (GAS), and gluteus maximus (GM) muscles
Measured: At baseline, post, 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in delayed onset of muscle soreness
Muscle soreness will be assessed during palpation of the muscle belly and the distal region
Measured: At baseline, post, at 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in repeated sprint ability (RSA)
5 x 30 m sprints will be performed with 25 seconds rest in-between
Measured: At baseline, at 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in sprint time of 10m
Sprint time will be assessed over a 10m distance using light cells.
Measured: At baseline, post, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in sprint time of 30m
Sprint time will be assessed over a 30m distance using light cells.
Measured: At baseline, post, 24, 48 and 72 hours post speed endurance maintenance protocols.
Change in field activity during the speed-endurance mainetnance protocols
Field activity will be continuously recorded during both speed endurance maintenance protocols using global positioning system (GPS) technology
Measured: For 20 minutes during the speed endurance maintenance training day
Change in heart rate during the speed-endurance mainetnance protocols
Heart rate will be continuously recorded during both speed endurance maintenance protocols using heart rate monitors
Measured: For 20 minutes during the speed endurance maintenance training day
Change in isometric peak torque
The isometric peak torque will be assessed on an isokinetic dyanmometer
Measured: At baseline, post, 1, 2, 3 and 24, 48 72 hours post speed endurance maintenance protocols.
Change in fatigue index of maximal voluntary isometric contraction (MVIC) during 10 seconds
Fatigue rate during MVIC will be estimated through the percent drop of peak torque between the first and the last three seconds of a 10-second maximal isometric contaction
Measured: At baseline, post, 1, 2, 3 and 24, 48 72 hours post speed endurance maintenance protocols.
Change in blood lactate
The blood lactate will be measured using a lactate plus system
Measured: At baseline and immediately post speed endurance maintenance protocols.
Secondary outcomes (9)
Body weight
Body weight will be measured on a beam balance with stadiometer
Measured: At baseline
Body height
Body height will be measured on a beam balance with stadiometer
Measured: At baseline
Maximal oxygen consumption (VO2max)
Maximal oxygen consumption will be measured by open circuit spirometry via breath by breath method
Measured: At baseline
Body fat
Body fat will be measured by using Dual-emission X-ray absorptiometry
Measured: At baseline
Lean body mass
Lean body mass will be measured by using Dual-emission X-ray absorptiometry
Measured: At baseline
Dietary intake
Dietary intake will be assessed using 7 -day diet recalls
Measured: Over a 7 -day period at baseline
Soccer Agility drill
The soccer agility drill will be assesed using light cells chronojump
Measured: At baseline
Yo-Yo Intermittent Recovery Test Level 2
The Yo-Yo Intermittent Recovery Test Level 2 is considered as a maximal aerobic endurance fitness test, involving running between markers placed 20 meters apart, at increasing speeds, until exhaustion.
Measured: At baseline
Yo-Yo Intermittent endurance Test Level 2
The Yo-Yo Intermittent endurance Test Level 2 evaluates an individual's aerobic endurance fitness, involving running between markers placed 20 meters apart, at increasing speeds, until exhaustion.
Measured: At baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Feb 2021
- Study start1 Apr 2021
- Primary completion20 Apr 2023
- Study completion31 Aug 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Muscle DamageStudies of the same condition, open and under way.
- More trials run by University of ThessalyThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 10 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Thessaly
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ioannis G. Fatouros, University of Thessaly
- Investigators
- Ioannis Fatouros, Prof, Study director, University of Thessaly
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04748315
- Sponsor's protocol ID
- Recovery-Maintenance-UTH
- Status last verified
- Jan 2024
- First submitted
- 25 Jan 2021
- Last updated
- 30 Jan 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Jan 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Recovery Kinetics After Speed-Εndurance Maintenance Training (SEMT) in Elite Male Soccer Players
- ClinicalTrials.gov ID
- NCT04748315
- Acronym / sponsor ID
- Recovery-Maintenance-UTH
- Conditions
- Muscle Damage
- Keywords
- muscle damage, Eccentric exercise, Speed maintenance training, Soccer, Recovery
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 10 participants (actual)
- Lead sponsor
- University of ThessalyUniversity, hospital or other
- Study start
- 1 Apr 2021 (actual)
- Primary completion
- 20 Apr 2023 (actual)
- Study completion
- 31 Aug 2023 (actual)
- First posted
- 10 Feb 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study will be to inestigate the recovery kinetics on performance, neuromuscular fatigue and muscle microtaruma that will occur after two speed-endurance maintenance training protocols in elite male soccer players. Also, this study will determine the comparison between two different speed endurance maintenance protocols in neuromuscular fatigue, muscle microtrauma indicators and performance factors. The training protocols will be differentiated in training work to rest ratio. The firts training protocol trial will comprise the work to rest ratio (1:1) and the other trial will comprise the work to rest ratio 1:3.
Detailed description
Speed endurance maintenance training is utilized in order to improve the repeated sprint and high speed running ability of soccer players during a soccer match. Also, speed endurance maintenance training includes soccer drills which stimulate high speed and powerful actions such as changes of directions, accelerations and decelerations. However these actions are associated with eccentric component and it is known that eccentric exercises induces muscle damage microtrauma. Thus, the aim of this study will be to investigate the recovery kinetics on performance, neuromuscular fatigue and muscle microtrauma that will occur after two speed-endurance maintenance training protocols in elite male soccer players. The speed endurance maintenance training (SEMT) sessions will be differentiated in training volume and specifically in the work to rest period. Specifically, a randomized three-trial, cross-over, repeated measures design will be applied. Elite male soccer players (aged 18-35 years) will participate in the present study. Also, it is considered necessary that the participants will not suffer from any musculoskeletal injuries that will limit their ability to perform the SEMT sessions. Also the participants will not be smokers and will not consume alcohol and ergogenic nutritional supplements before and during the study.
In the first phase all participants will sign an informed consent form after they will be informed about all benefits and risks of this study and they will sign a recent historical of musculoskeletal injury or illness form. Subsequently, fasting blood samples will be collected by venipuncture using a disposable needle (10-gauge) in order to estimate muscle damage concentration markers (CK), blood lactate and inflammation markers (WBC). After, delayed onset muscle soreness (DOMS) in the knee flexors (KF) and extensors (KE) of both limbs, body weight (BW), height and body composition (DXA method) will be measured in the lab. Completing the first phase, participants will be instructed by a dietitian how to record a 7 days diet recalls estimating that the energy intake during the trials will be the same. The counter movement jump (CMJ) will be measured 24 hour after (second phase) on a force platform using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg. During the CMJ will be measured the jump height (cm), the ground reaction force (N), the peak and mean power (W/kg), the vertical stiffness (Kvert, N/m/kg) and the peak rate of force development (RFD, N/s), while at the same time will be evaluated the change in peak and mean normalized EMG during the eccentric and concentric phases of the counter movement jump, for the vastus lateralis (VL), biceps femoris (BF), gastrocnemius (GAS), and gluteus maximus (GM) muscles. Electromyography data will be collected wirelessly at 2.000 Hz using a Myon MA-320 EMG system. The peak eccentric and concentric isokinetic torque of the knee flexors and extensors, in both limbs will be evaluated on an isokinetic dynamometer at 60°/sec. Also, the isometric peak torque of the knee extensors will be evaluated at 65o in both limbs. Also the fatigue rate during maximal voluntary isometric contraction will be estimated through the percent drop of peak torque between the first and the last three seconds of a 10-secong maximal isometric contraction. Also, the speed of 10m and 30m will be measured using light cells Chronojump system. The repeated sprint ability (RSA) (5x30m) will be measure using light cells Chronojump with 25 seconds rest in-between.
The soccer agility drill with a ball will be measured using light cells Chronojump in order to evaluate the soccer technical skills, 24 hour after. Finally, Open-circuit spirometry will be utilized for assessment of maximal oxygen consumption (VO2max) using an automated online pulmonary gas exchange system via breath-by-breath analysis during a graded exercise testing on a treadmill. The ability to recover after repeated intense exercise will be evaluated through the YO-YO Intermittent Recovery test level 2 and YO-YO Intermittent Endurance test level 2. 96 hours after, the participants are going to perform one of the two speed endurance maintenance training session randomly in the field. The SEMT(1:1) session will include 1 set, 6 repetitions per set and the work to rest ratio will be 1:1. The SEMT(1:3) session will iclude 1 set, 6 repetitions per set and the work to rest ratio will be 1:3. During the sessions will be assessed the change in Heart rate using a heart rate monitor and the field activity will be recorded using a global positiong system (GPS). The blood lactate will be evaluated immediately after each session. The DOMS indicator in the knee flexors (KF) and extensors (KE) of both limbs will be evaluated immediately after, 1h, 2h, 3h, 24h, 48h, and 72 hours after each session. The isometric peak torque of the knee extensors will be evaluated at 65° in limbs, post and at 1h, 2h and 3h, hours after each session. Also the fatigue rate during maximal voluntary isometric contraction will be estimated through the percent drop of peak torque between the first and the last three seconds of a 10-secong maximal isometric contraction.
Blood samples will be collected at 24h, 48h, and 72 hours after sessions. The counter movement jump (CMJ) will be measured immediately after the session, at 1h, 2h, 3h, at 24h, 48h and 72 hours after session on a force platform using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg. During the CMJ will be measured the jump height (cm), the ground reaction force (N), the peak and mean power (W/kg), the vertical stiffness (Kvert, N/m/kg) and the peak rate of force development (RFD, N/s), while at the same time will be evaluated the change in peak and mean normalized EMG during the eccentric and concentric phases of the counter movement jump, for the vastus lateralis (VL), biceps femoris (BF), gastrocnemius (GAS), and gluteus maximus (GM) muscles. Electromyography data will be collected wirelessly at 2.000 Hz using a Myon MA-320 EMG system. Also, the speed of 10m and 30m will be measured using light cells Chronojump system immediately after, at 24h, 48h and 72 hours after session. Finally the RSA test will be measured at 24h, 48h and 72 hours after sessions. Α 2 - week washout period will be adapted among trials. After, the participants will perform the process until they complete the trials.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (investigator)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| SEMT(1:1) | Experimental | Other: SEMT(1:1)Participants in this arm will perform an a speed endurance maintenance training consisted of work to rest ratio 1:1. |
| SEMPT(1:3) | Experimental | Other: SEMT (1:3)Participants in this arm will perform an a speed endurance maintenance training consisted of work to rest ratio 1:3. |
| Control | No intervention | –Participants in this arm will receive no intervention |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Aged between 18 and 35 years
- Active soccer players who participate on a competitive soccer level at least for 4 years(≥5 sessions per week ≥1 match per week)
- Free of chronic diseases
- Free of musculoskeletal injury
- Participants should be non-smokers
Key exclusion criteria (3 listed)
- Musculoskeletal injury
- Chronic disease
- Use of alcohol, caffeine and any type of ergogenic supplements or medication before (≥ 6 months) and throughout the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| SEMT(1:1)Soccer trainning protocolo will be performed on an work to rest ratio 1:1 and the trainning volume will consist of 1 set and 6 repetitions per set | Other | SEMT(1:1) |
| SEMT (1:3)Soccer trainning protocolo will be performed on an work to rest ratio 1:3 and the trainning volume will consist of 1 set and 6 repetitions per set | Other | SEMPT(1:3) |
Primary outcome
Change in white blood cell count
Time frame: At baseline, at 24, 48 and 72 hours post speed endurance maintenance protocols.
White blood cell count will be measured using an automatic blood analyzer
Change in Creatine kinase in blood
Time frame: At baseline, at 24, 48 and 72 hours post speed endurance maintenance protocols.
Creatine kinase will be measured in plasma
Change in countermovement jump height
Time frame: At baseline, post, 1, 2,3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Countermovement jump height will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Change in ground reaction force (GRF) during countermovement jump test
Time frame: At baseline, at post, at 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
The ground reaction force will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Change in peak power during countermovement jump test
Time frame: At baseline, post 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
The peak power will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Change in mean power during countermovement jump test
Time frame: At baseline, post, 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
The mean power will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Change in vertical stifness during countermovement jump test
Time frame: At baseline, post, 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
The vertical stifness will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Change in peak rate of force development during countermovement jump test
Time frame: At baseline, post, 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
The peak rate of force development will be measured using two force platforms at 1000Hz, with each foot in parallel on the two platforms providing a seperate yet time-synchronized measurement of the jump height for each leg
Change in peak normalized EMG during the eccentric and concentric phases of the countermovement jmp test
Time frame: At baseline, post, 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Electromyography data will be collected wirelessly at 2000Hz using a Myon MA-320 EMG system (Myon AG, Schwarzenberg, Switzerland) for the vastus lateralis (VL), biceps femoris (BF), gastrocnemius (GAS), and gluteus maximus (GM) muscles
Change in mean normalized EMG during the eccentric and concentric phases of the countermovement jump test
Time frame: At baseline, post, 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Electromyography data will be collected wirelessly at 2000Hz using a Myon MA-320 EMG system (Myon AG, Schwarzenberg, Switzerland) for the vastus lateralis (VL), biceps femoris (BF), gastrocnemius (GAS), and gluteus maximus (GM) muscles
Change in delayed onset of muscle soreness
Time frame: At baseline, post, at 1, 2, 3, 24, 48 and 72 hours post speed endurance maintenance protocols.
Muscle soreness will be assessed during palpation of the muscle belly and the distal region
Change in repeated sprint ability (RSA)
Time frame: At baseline, at 24, 48 and 72 hours post speed endurance maintenance protocols.
5 x 30 m sprints will be performed with 25 seconds rest in-between
Change in sprint time of 10m
Time frame: At baseline, post, 24, 48 and 72 hours post speed endurance maintenance protocols.
Sprint time will be assessed over a 10m distance using light cells.
Change in sprint time of 30m
Time frame: At baseline, post, 24, 48 and 72 hours post speed endurance maintenance protocols.
Sprint time will be assessed over a 30m distance using light cells.
Change in field activity during the speed-endurance mainetnance protocols
Time frame: For 20 minutes during the speed endurance maintenance training day
Field activity will be continuously recorded during both speed endurance maintenance protocols using global positioning system (GPS) technology
Change in heart rate during the speed-endurance mainetnance protocols
Time frame: For 20 minutes during the speed endurance maintenance training day
Heart rate will be continuously recorded during both speed endurance maintenance protocols using heart rate monitors
Change in isometric peak torque
Time frame: At baseline, post, 1, 2, 3 and 24, 48 72 hours post speed endurance maintenance protocols.
The isometric peak torque will be assessed on an isokinetic dyanmometer
Change in fatigue index of maximal voluntary isometric contraction (MVIC) during 10 seconds
Time frame: At baseline, post, 1, 2, 3 and 24, 48 72 hours post speed endurance maintenance protocols.
Fatigue rate during MVIC will be estimated through the percent drop of peak torque between the first and the last three seconds of a 10-second maximal isometric contaction
Change in blood lactate
Time frame: At baseline and immediately post speed endurance maintenance protocols.
The blood lactate will be measured using a lactate plus system
9 secondary outcomes
Body weight
Time frame: At baseline
Body height
Time frame: At baseline
Maximal oxygen consumption (VO2max)
Time frame: At baseline
Body fat
Time frame: At baseline
Lean body mass
Time frame: At baseline
Dietary intake
Time frame: Over a 7 -day period at baseline
Soccer Agility drill
Time frame: At baseline
Yo-Yo Intermittent Recovery Test Level 2
Time frame: At baseline
Yo-Yo Intermittent endurance Test Level 2
Time frame: At baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Jan 2024.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ioannis Fatouros, Prof study director
University of Thessaly
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing SEMT(1:1) and SEMT (1:3) in people with Muscle Damage, run by University of Thessaly at 1 site in Greece.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Jan 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Greece. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in white blood cell count (time frame: At baseline, at 24, 48 and 72 hours post speed endurance maintenance protocols.). The study lists 19 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Jan 2024.