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Stigma, SocialNCT04760223

Reducing Stigma Towards Depression Among Adolescents

A study testing Video intervention in people with Stigma, Social, run by Research Foundation for Mental Hygiene, Inc. at 2 sites in United States.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The investigators conducted a randomized controlled study to test the utility of a brief video-based intervention to: 1) reduce stigma towards depression, and 2) increase treatment-seeking intentions among adolescents. Read more about this study

Who is it for?
Ages 14 to 18 yearsHealthy volunteers can take part
Conditions the study is for
Stigma, Social
What is being tested?
Video intervention
Could I receive a placebo?
Yes, some participants may receive a placebo
How many people
1,183 participants
Where
2 sitesUnited States
Study dates
1 Jan 2021to 1 Feb 2021
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 14 to 18 years
  • All sexes
  • Healthy volunteers accepted
  • Child, Adult

Who may be able to join

  • 14-18-year-old
  • US residents
  • English speaker

Who cannot join

  • None

Trial locations and contacts

2 sites in 1 country.

United States2 sites
  • Yale University

    New Haven, Connecticut, 06520

  • New York State Psychiatric Institute

    New York, New York, 10032

Other trials in United States

About this study

Official title: Reducing Depression-related Stigma and Increasing Treatment-seeking Among Adolescents: Randomized Controlled Trial of a Brief Video Intervention

The investigators conducted a randomized controlled study to test the utility of a brief video-based intervention to: 1) reduce stigma towards depression, and 2) increase treatment-seeking intentions among adolescents.

Read the detailed description

Young people present with the higher prevalence of mental health disorders compared to individuals at any other age, with up to 20% of adolescents likely to experience mental health disorders. Around 50% of mental health conditions start before the age of 14 and the onset of 75% of cases is before the age of 18. Depression is the most common diagnosis and epidemiological studies suggest that at any one time 8% to 10% of adolescents have severe depression. This means that the major burden of assessing and managing adolescent depression falls on primary care practitioners. Depression is a principal cause of illness and disability in teenagers, and suicide is the third most common cause of death among older adolescents. Mental health problems can significantly affect the development of children and young people having an enduring impact on their health and social functioning in adulthood. However, 75% of adolescents with mental health problems are not in contact with mental health services,8 and the primary reason for the reluctance to seek help is stigma.

Stigma refers to negative beliefs and stereotypes held toward a specific group of people and adversely affects people with mental illness. Public stigma refers to negative attitudes and beliefs that motivate individuals to fear, reject, avoid, and discriminate against people with mental illness. Individuals with mental illness expect to face prejudice and discrimination (anticipated stigma) and internalize public stereotypes of people with mental illness (self-stigma). Adolescents are particularly aware of how others perceive them and care greatly about what their peers think of them. Public stigma toward youngsters with mental illness has been identified as a barrier to seeking help; therefore, reducing public stigma among young people at risk for or even experiencing depression could enhance their receptivity to seeking help or treatment.

Applying strategies to reduce stigma towards mental health care among adolescents with high levels of depression may prevent worsening of symptoms, ameliorate impaired functioning, and reduce risks for long-term psychiatric illness. Among possible strategies, studies19 have shown that social contact is the most effective type of intervention to reduce stigmatizing attitudes. Social contact involves interpersonal contact with members of the stigmatized group: members of the general public who meet and interact with individuals who suffer from depression are likely to lessen their stigma. Corrigan identified the most important ingredients of contact-based programs: an empowered presenter with lived experience who attains his/her goals (e.g., "I was able to fight the depression and go back to school"). Although direct, in-person social contact, as well as indirect, video-based social contact have effectively improved attitudes toward mental issues and care, the latter can be implemented on a larger scale, use minimal resources and be easily disseminated.

The purpose of this study is to: (1) examine adolescents' stigma-related attitudes towards depression; and (2) test the utility of a brief video-based intervention in reducing stigma towards depression and increasing help-seeking intentions.

The investigators propose to randomly assign 1,000 individuals aged 14-18 in to either: (a) brief video-based intervention 1 ('Video 1'); (b) brief video-based intervention 2 ('Video 2'); or (c) no intervention video control arm ('Control'). The intervention videos will focus on empowered presenters with depression. The presenters will be 16-year-old adolescent professional actors, one of them is a boy (Video 1), one is a girl (Video 2). They each will share his/her personal story regarding depression and describe how social support from family, friends, and professionals have helped them overcome their symptoms and recover. The third group will watch a same length video with unrelated contents. Assessments will occur at baseline and at post-intervention and will tap into demographic identifiers and attitudes around stigma and help-seeking questionnaires.

Actors will be hired through the Child Study Center, and / or through the Standardized Patient Program of Teaching and Learning Center, Yale School of Medicine. Actors will be compensated and follow standardized patient best practices, including those specifically pertaining to under-age actors.

Conditions
Stigma, Social
Being tested
Video intervention
Medical subject headings
Social Stigma

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Video interventionBehavioural

    a 100-second video, presenting a personal story of a boy/girl dealing with depression

Study groups in NCT04760223
Study groupRoleWhat they receive
Video intervention 1ExperimentalWe presented a 100-second video to study participants to reduce stigma towards depression (a boy presenter). The protagonist discussed his own depression and how getting help assist him.
Receives: Behavioral: Video intervention
Video intervention 2ExperimentalWe presented a 100-second video to study participants to reduce stigma towards depression (a girl presenter). The protagonist discussed his own depression and how getting help assist her.
Receives: Behavioral: Video intervention
control video 1Placebo comparatorA 100-second video presenting a boy without depression
Receives: Behavioral: Video intervention
control video 2Placebo comparatorA 100-second video presenting a girl without depression
Receives: Behavioral: Video intervention

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Stigma levels

    Level of stigma towards depression measured by the 9-item Depression Stigma Scale (DSS). This is a 9-item self report questionnaire to measure the personal stigma towards depression. It has 5-point Likert scale tanging from strongly disagree (1) and strongly agree (5). It had test-retest reliability of 0.71 and internal consistency of 0.76 (Griffiths KM et al. 2004)

    Measured: Through the study completion (pre and post-intervention), an average of one month

  2. help-seeking intentions

    The General Help-Seeking Questionnaire (GHSQ) has been developed to measure help-seeking intentions from different sources (friend, parent, mental health professional, and others) and is divided into personal-emotional problems and suicidal thoughts. The instrument consists of 10 items repeated twice for each part, measured with a 7-point Likert scale ranging from 1 (extremely unlikely) to 7 (extremely likely). One question is stated as "I would not seek help from anyone" and is reverse scored. Higher scores on this scale indicate more help-seeking. The GHSQ has shown good psychometric properties: Cronbach's alpha = 0.70, and test-retest of 0.86 for personal-emotional problems, and Cronbach's alpha = 0.83, and test-retest of 0.88 for suicidal thoughts (Wilson CJ et al. 2008)

    Measured: Through the study completion (pre and post-intervention), an average of one month

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted18 Feb 2021
  2. Study start1 Jan 2021
  3. Primary completion12 Jan 2021
  4. Study completion1 Feb 2021

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Health services research
Allocation
Randomised
Intervention model
Parallel groups
Model description
Randomized controlled trial
Masking
Single blind
Who is masked
Participant
Enrolment
1,183 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT04760223
Sponsor's protocol ID
ResearchFMH
Status last verified
Feb 2021
First submitted
11 Feb 2021
Last updated
18 Feb 2021
Results posted
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Amsalem D, Martin A. Reducing depression-related stigma and increasing treatment seeking among adolescents: randomized controlled trial of a brief video intervention. J Child Psychol Psychiatry. 2022 Feb;63(2):210-217. doi: 10.1111/jcpp.13427. Epub 2021 Apr 6.

    PubMed 33821507

Questions about this trial

What is this clinical trial studying?

A study testing Video intervention in people with Stigma, Social, run by Research Foundation for Mental Hygiene, Inc. at 2 sites in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 18 Feb 2021. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Stigma levels (time frame: Through the study completion (pre and post-intervention), an average of one month). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT04760223, which also lists 1 linked publication.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Feb 2021; AzTrials last refreshed its copy on 30 Oct 2026.

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