Healthy IndividualsESTI-STSNCT04772417
The Effects of Standardized vs Individualized Seat Height on 1-minute Sit-to-stand Performance
An observational study of Healthy Individuals, run by University of Zurich at 1 site in Switzerland.
Trial summary
The 1-minute sit-to-stand test (1MSTS) is a widely used functional capacity test and has promising predictive potential. Current standards of practice suggest the use of a chair with a standardized height. However, this practice makes the test more demanding for taller individuals than for shorter individuals. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Healthy Individuals
- What is being tested?
- Standardized 1-minute sit-to-stand test and Individualized 1-minute sit-to-stand test
- How many people
- 30 participants
- Where
- 1 siteSwitzerland
- Study dates
- 20 Apr 2021to 3 Nov 2022
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Healthy individuals
Who may be able to join
- Informed consent as documented by signature
- Age 18 and older
- Healthy
- Ability to conduct a 1-minute sit-to-stand-test
- Ability to follow study procedures and instructions in German
Who cannot join
- Known cardiopulmonary or metabolic diseases (e.g., heart disease, diabetes mellitus etc.)
- Smoking (ex-smoker allowed; if they stopped smoking at least one year before the study inclusion)
- Physical or intellectual impairment precluding informed consent or protocol adherence
- Respiratory infection in the last two weeks
- Pain during sit-to-stand movement
Trial locations and contacts
1 site in 1 country.
About this study
The 1-minute sit-to-stand test (1MSTS) is a widely used functional capacity test and has promising predictive potential. Current standards of practice suggest the use of a chair with a standardized height. However, this practice makes the test more demanding for taller individuals than for shorter individuals. This implies over- or underestimation of functional capacity depending on body morphology.
Therefore, the aim of this study is to investigate the influence of knee joint angle, femur length and bodyweight on the 1MSTS performance in healthy subjects with different morphology.
Read the detailed description
This is a randomized cross-over trial with the participants performing both procedures twice in one visit. Sufficient breaks in between the tests is granted.
- Conditions
- Healthy Individuals
- Being tested
- Standardized 1-minute sit-to-stand test, Individualized 1-minute sit-to-stand test
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Standardized 1-minute sit-to-stand testDiagnostic test
The individuals perform two tests from a standardized chair (seat height 46cm).
Individualized 1-minute sit-to-stand testDiagnostic test
The individuals perform two tests from an individualized chair (seat height adjusted so that the starting position elicits a knee flexion angle of 90°).
What is being measured
The primary outcome is the main question the study is designed to answer.
Repetitions in the 1-minute sit-to-stand test
Comparison between the procedures
Measured: Day 1
Secondary outcomes (1)
Predictors towards performance in the 1-minute sit-to-stand test
Comparison between the procedures
Measured: Day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Feb 2021
- Study start20 Apr 2021
- Primary completion3 Nov 2022
- Study completion3 Nov 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Healthy IndividualsStudies of the same condition, open and under way.
- More trials run by University of ZurichThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Zurich
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04772417
- Sponsor's protocol ID
- 2020-02945
- Acronym
- ESTI-STS
- Status last verified
- Nov 2022
- First submitted
- 21 Feb 2021
- Last updated
- 8 Nov 2022
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: On reasonable request
Publications
Kuhn M, Vollenweider S, Clarenbach CF, Kohlbrenner D. The effects of standardised versus individualised seat height on 1-minute sit-to-stand test performance in healthy individuals: a randomised crossover trial. Eur J Appl Physiol. 2023 Jul;123(7):1543-1551. doi: 10.1007/s00421-023-05174-8. Epub 2023 Mar 17.
PubMed 36932213
Study at a glance
From the registry record, last updated by the sponsor on 8 Nov 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Standardized vs Individualized Seat Height on 1-minute Sit-to-stand Performance
- ClinicalTrials.gov ID
- NCT04772417
- Acronym / sponsor ID
- ESTI-STS / 2020-02945
- Conditions
- Healthy Individuals
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- University of ZurichUniversity, hospital or other
- Study start
- 20 Apr 2021 (actual)
- Primary completion
- 3 Nov 2022 (actual)
- Study completion
- 3 Nov 2022 (actual)
- First posted
- 26 Feb 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The 1-minute sit-to-stand test (1MSTS) is a widely used functional capacity test and has promising predictive potential. Current standards of practice suggest the use of a chair with a standardized height. However, this practice makes the test more demanding for taller individuals than for shorter individuals. This implies over- or underestimation of functional capacity depending on body morphology.
Therefore, the aim of this study is to investigate the influence of knee joint angle, femur length and bodyweight on the 1MSTS performance in healthy subjects with different morphology.
Detailed description
This is a randomized cross-over trial with the participants performing both procedures twice in one visit. Sufficient breaks in between the tests is granted.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Healthy individuals
Key inclusion criteria (5 listed)
- Informed consent as documented by signature
- Age 18 and older
- Healthy
- Ability to conduct a 1-minute sit-to-stand-test
- Ability to follow study procedures and instructions in German
Key exclusion criteria (5 listed)
- Known cardiopulmonary or metabolic diseases (e.g., heart disease, diabetes mellitus etc.)
- Smoking (ex-smoker allowed; if they stopped smoking at least one year before the study inclusion)
- Physical or intellectual impairment precluding informed consent or protocol adherence
- Respiratory infection in the last two weeks
- Pain during sit-to-stand movement
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Standardized 1-minute sit-to-stand testThe individuals perform two tests from a standardized chair (seat height 46cm). | Diagnostic test | – |
| Individualized 1-minute sit-to-stand testThe individuals perform two tests from an individualized chair (seat height adjusted so that the starting position elicits a knee flexion angle of 90°). | Diagnostic test | – |
Primary outcome
Repetitions in the 1-minute sit-to-stand test
Time frame: Day 1
Comparison between the procedures
1 secondary outcome
Predictors towards performance in the 1-minute sit-to-stand test
Time frame: Day 1
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Nov 2022.
- Derived from this study: PubMed 36932213Kuhn M, Vollenweider S, Clarenbach CF, Kohlbrenner D. The effects of standardised versus individualised seat height on 1-minute sit-to-stand test performance in healthy individuals: a randomised crossover trial. Eur J Appl Physiol. 2023 Jul;123(7):1543-1551. doi: 10.1007/s00421-023-05174-8. Epub 2023 Mar 17.
- Individual participant dataSharing planned: Undecided. On reasonable request
Related trials for Healthy Individuals
Recruiting
Investigate the Relationship Between Catastrophizing and the Perception of Itch Intensity in Healthy Individuals
Histamine, Cowhage
Recruiting
Metabolic Impact of VLCPUFA-Rich Fish Oil: A Clinical Study on Omega-3 Index Enhancement in Healthy Individuals
Fatty Acids, Omega-3, Fish Oils
Not yet recruitingObservational study
Microneurographic Assessment of Peripheral Nerves in Healthy Volunteers and Individuals With Sensory Dysfunction Caused by Inherited Mutations in the PIEZO2 Gene
PIEZO2-Deficiency Syndrome
RecruitingObservational study
Studies of Skin Microbes in Healthy People and in People With Skin Conditions
Eczema, Atopic Dermatitis
Active, not recruitingObservational study
C. Difficile Toxin Levels in Stool From Healthy Individuals Following Standard of Care Antibiotic Treatment for CDI.
Clostridioides Difficile Infection Recurrence
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Healthy Individuals, run by University of Zurich at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Nov 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Repetitions in the 1-minute sit-to-stand test (time frame: Day 1). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04772417, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Nov 2022.