Extensor LagNCT04790669
DAPRE Exercises Technique and CKC Exercises on Extensor Lag in Post Knee Stiffness
A study testing Daily adjustable progressive resistance exercises (DAPRE) and Close kinetic chain exercises (CKC). in people with Extensor Lag and Post-operative Knee Stiffness, run by Riphah International University at 1 site in Pakistan.
Trial summary
This project was a Randomized clinical trial conducted on extensor lag in post-operative knee stiffness patient to compare the effects of The Daily Adjustable Progressive Resistive Exercise (DAPRE) technique versus Close kinetic chain (CKC) exercise training in people who had undergone knee stiffness, m so that we can… Read more about this study
- Who is it for?
- Ages 30 to 60 years
- Conditions the study is for
- Extensor Lag, Post-operative Knee Stiffness
- What is being tested?
- Daily adjustable progressive resistance exercises (DAPRE) and Close kinetic chain exercises (CKC).
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 22 participants
- Where
- 1 sitePakistan
- Study dates
- 15 Oct 2020to 20 May 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Post-operative knee stiffness (patients with 1-3 month stiffness).
- Both male and female , age 30-60 years.
- Willing to participate in research.
Who cannot join
- Pre-operative knee stiffness
- Severe cardiopulmonary disease
- Patients undergoing chemotherapy
- Any traumatic injury/ Acute inflammatory muscular pathology
- TKR \& hip pathology and replacement
- Meniscal tear
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Riphah International University
Lahore, Punjab Province, 54000
About this study
Official title: Comparative Effects of Daily Adjustable Progressive Resistance Exercises Technique and Close Kinetic Chain Exercises on Extensor Lag in Post-operative Knee Stiffness
This project was a Randomized clinical trial conducted on extensor lag in post-operative knee stiffness patient to compare the effects of The Daily Adjustable Progressive Resistive Exercise (DAPRE) technique versus Close kinetic chain (CKC) exercise training in people who had undergone knee stiffness, m so that we can have best treatment option for patients with extensor lag.
Read the detailed description
Probability Convenient sampling was done. Patients following eligibility criteria from Physiotherapy department of PSRD, Lahore, were considered. Sample size was calculated with Epi-tool calculator. 22 Participants were randomly allocated in two groups equally via convenient sampling method. Baseline assessment was done initially. Group A, 11 participants will receive Conventional physiotherapy treatment in addition to DAPRE technique by leg extension machine. In DAPRE technique, four sets of exercises were performed. The first two sets of exercise consisted of ten and then six repetitions, per- formed against one-half and three-fourths of the previously established working weight. Working weight is the amount of weight a patient uses during an individual session. The full working weight was used on the third set, and the patient performed as many repetitions as possible. After performing each of the third and fourth sets, patients rested for 1 min. 6 weeks (3 sessions per week)• Hot pack: 10 min• Stretching of calf and hamstring muscle: 10 min. Group B, 11 participants will receive Conventional physiotherapy treatment in addition to close kinetic chain exercises. Close kinetic chain exercises for extensor lag is seated leg press, double or single one third knee bend, step up and down exercise, wall slide with weight. Treatment time will be 30 minutes and three session per week will be applied on alternate day for up to 6 weeks. Pre interventional readings will be taken at baseline \& post interventional readings at 6th week. 6 weeks (3 sessions per week) • Hot pack: 10 min • Stretching of calf and hamstring muscle: 10 min. All participants were provided written informed consent prior to commencement of the procedures. They were free to quit the treatment at any stage of research. Data was analyzed by using SPSS version 23.
- Conditions
- Extensor Lag, Post-operative Knee Stiffness
- Being tested
- Daily adjustable progressive resistance exercises (DAPRE), Close kinetic chain exercises (CKC).
- Keywords
- DAPRE, CKC exercises, Extensor lag
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Daily adjustable progressive resistance exercises (DAPRE)Procedure or surgery
Daily adjustable progressive resistance exercises (DAPRE) In Group A, 11 participants were received Conventional physiotherapy treatment in addition to DAPRE technique by leg extension machine. In DAPRE technique, four sets of exercises were performed. The first two sets of exercise consisted of ten and then six repetitions, per- formed against one-half and three-fourths of the previously established working weight. Working weight is the amount of weight a patient uses during an individual session. The full working weight was used on the third set, and the patient performed as many repetitions as possible. After performing each of the third and fourth sets, patients rested for 1 min.6 weeks (3 sessions per week)• Hot pack: 10 min• Stretching of calf and hamstring muscle: 10 min. Assessment was done via WOMAC index, universal goniometer, numeric pain rating scale \& sphygmomanometer.
Close kinetic chain exercises (CKC).Procedure or surgery
Close kinetic chain exercises (CKC). In Group B, 11 participants was received Conventional physiotherapy treatment in addition to close kinetic chain exercises. Close kinetic chain exercises for extensor lag was seated leg press, double or single one third knee bend, step up and down exercise, wall slide with weight. Treatment time was 30 minutes and three session per week was applied on alternate day for up to 6 weeks. Pre interventional readings will be taken at baseline \& post interventional readings at 6th week. 6 weeks (3 sessions per week) • Hot pack: 10 min • Stretching of calf and hamstring muscle: 10 min. Assessment was done via WOMAC index, universal goniometer, numeric pain rating scale \& sphygmomanometer.
| Study group | Role | What they receive |
|---|---|---|
| Daily adjustable progressive resistance exercises (DAPRE) | Experimental | DAPRE technique, hot pack, stretching exercises. Receives: Procedure: Daily adjustable progressive resistance exercises (DAPRE) |
| Close kinetic chain exercises (CKC). | Experimental | CKC exercises, hot pack, stretching exercises Receives: Procedure: Close kinetic chain exercises (CKC). |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in knee functional Improvement by WOMAC index
By using WOMAC index, knee functional improvement was checked at baseline \& post interventional readings at 6th week.
Measured: 6 weeks (3 sessions per week).
Change in knee range of motion by universal goniometer.
Change in ROM at baseline \& post interventional readings at 6th week.
Measured: 6 weeks (3 sessions per week).
Change in pain by 'Numeric Pain Rating Scale'
Change in pain was measured at baseline \& post interventional readings at 6th week.
Measured: 6 weeks (3 sessions per week).
Change in strength by Sphygmomanometer
Change in strength was measured at baseline \& post interventional readings at 6th week.
Measured: 6 weeks (3 sessions per week).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Mar 2021
- Study start15 Oct 2020
- Primary completion20 May 2021
- Study completion20 May 2021
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Extensor LagStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 22 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Rabiya Noor, PhD, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04790669
- Sponsor's protocol ID
- REC/Lhr/20/021 Shanza Tanveer
- Status last verified
- Aug 2021
- First submitted
- 6 Mar 2021
- Last updated
- 2 Sep 2021
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Ardali G. A daily adjustable progressive resistance exercise protocol and functional training to increase quadriceps muscle strength and functional performance in an elderly homebound patient following a total knee arthroplasty. Physiother Theory Pract. 2014 May;30(4):287-97. doi: 10.3109/09593985.2013.868064. Epub 2014 Jan 7.
PubMed 24397371Wawrzyniak JR, Tracy JE, Catizone PV, Storrow RR. Effect of closed chain exercise on quadriceps femoris peak torque and functional performance. J Athl Train. 1996 Oct;31(4):335-40.
PubMed 16558420Knight KL. Quadriceps Strengthening with the DAPRE Technique: Case studies with Neurological Implications. J Orthop Sports Phys Ther. 1990;12(2):66-71. doi: 10.2519/jospt.1990.12.2.66.
PubMed 18787253
Study at a glance
From the registry record, last updated by the sponsor on 2 Sep 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Daily Adjustable Progressive Resistance Exercises Technique and Close Kinetic Chain Exercises on Extensor Lag in Post-operative Knee Stiffness
- ClinicalTrials.gov ID
- NCT04790669
- Acronym / sponsor ID
- REC/Lhr/20/021 Shanza Tanveer
- Conditions
- Extensor Lag, Post-operative Knee Stiffness
- Keywords
- DAPRE, CKC exercises, Extensor lag
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 22 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 15 Oct 2020 (actual)
- Primary completion
- 20 May 2021 (actual)
- Study completion
- 20 May 2021 (actual)
- First posted
- 10 Mar 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This project was a Randomized clinical trial conducted on extensor lag in post-operative knee stiffness patient to compare the effects of The Daily Adjustable Progressive Resistive Exercise (DAPRE) technique versus Close kinetic chain (CKC) exercise training in people who had undergone knee stiffness, m so that we can have best treatment option for patients with extensor lag.
Detailed description
Probability Convenient sampling was done. Patients following eligibility criteria from Physiotherapy department of PSRD, Lahore, were considered. Sample size was calculated with Epi-tool calculator. 22 Participants were randomly allocated in two groups equally via convenient sampling method. Baseline assessment was done initially. Group A, 11 participants will receive Conventional physiotherapy treatment in addition to DAPRE technique by leg extension machine. In DAPRE technique, four sets of exercises were performed. The first two sets of exercise consisted of ten and then six repetitions, per- formed against one-half and three-fourths of the previously established working weight. Working weight is the amount of weight a patient uses during an individual session. The full working weight was used on the third set, and the patient performed as many repetitions as possible. After performing each of the third and fourth sets, patients rested for 1 min. 6 weeks (3 sessions per week)• Hot pack: 10 min• Stretching of calf and hamstring muscle: 10 min. Group B, 11 participants will receive Conventional physiotherapy treatment in addition to close kinetic chain exercises. Close kinetic chain exercises for extensor lag is seated leg press, double or single one third knee bend, step up and down exercise, wall slide with weight. Treatment time will be 30 minutes and three session per week will be applied on alternate day for up to 6 weeks. Pre interventional readings will be taken at baseline \& post interventional readings at 6th week. 6 weeks (3 sessions per week) • Hot pack: 10 min • Stretching of calf and hamstring muscle: 10 min. All participants were provided written informed consent prior to commencement of the procedures. They were free to quit the treatment at any stage of research. Data was analyzed by using SPSS version 23.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Daily adjustable progressive resistance exercises (DAPRE) | Experimental | Procedure: Daily adjustable progressive resistance exercises (DAPRE)DAPRE technique, hot pack, stretching exercises. |
| Close kinetic chain exercises (CKC). | Experimental | Procedure: Close kinetic chain exercises (CKC).CKC exercises, hot pack, stretching exercises |
Who may qualify
- Ages
- 30 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Post-operative knee stiffness (patients with 1-3 month stiffness).
- Both male and female , age 30-60 years.
- Willing to participate in research.
Key exclusion criteria (6 listed)
- Pre-operative knee stiffness
- Severe cardiopulmonary disease
- Patients undergoing chemotherapy
- Any traumatic injury/ Acute inflammatory muscular pathology
- TKR \& hip pathology and replacement
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Daily adjustable progressive resistance exercises (DAPRE)Daily adjustable progressive resistance exercises (DAPRE) In Group A, 11 participants were received Conventional physiotherapy treatment in addition to DAPRE technique by leg extension machine. In DAPRE technique, four sets of exercises were performed. The first two sets of exercise consisted of ten and then six repetitions, per- formed against one-half and three-fourths of the previously established working weight. Working weight is the amount of weight a patient uses during an individual session. The full working weight was used on the third set, and the patient performed as many repetitions as possible. After performing each of the third and fourth sets, patients rested for 1 min.6 weeks (3 sessions per week)• Hot pack: 10 min• Stretching of calf and hamstring muscle: 10 min. Assessment was done via WOMAC index, universal goniometer, numeric pain rating scale \& sphygmomanometer. | Procedure or surgery | Daily adjustable progressive resistance exercises (DAPRE) |
| Close kinetic chain exercises (CKC).Close kinetic chain exercises (CKC). In Group B, 11 participants was received Conventional physiotherapy treatment in addition to close kinetic chain exercises. Close kinetic chain exercises for extensor lag was seated leg press, double or single one third knee bend, step up and down exercise, wall slide with weight. Treatment time was 30 minutes and three session per week was applied on alternate day for up to 6 weeks. Pre interventional readings will be taken at baseline \& post interventional readings at 6th week. 6 weeks (3 sessions per week) • Hot pack: 10 min • Stretching of calf and hamstring muscle: 10 min. Assessment was done via WOMAC index, universal goniometer, numeric pain rating scale \& sphygmomanometer. | Procedure or surgery | Close kinetic chain exercises (CKC). |
Primary outcome
Change in knee functional Improvement by WOMAC index
Time frame: 6 weeks (3 sessions per week).
By using WOMAC index, knee functional improvement was checked at baseline \& post interventional readings at 6th week.
Change in knee range of motion by universal goniometer.
Time frame: 6 weeks (3 sessions per week).
Change in ROM at baseline \& post interventional readings at 6th week.
Change in pain by 'Numeric Pain Rating Scale'
Time frame: 6 weeks (3 sessions per week).
Change in pain was measured at baseline \& post interventional readings at 6th week.
Change in strength by Sphygmomanometer
Time frame: 6 weeks (3 sessions per week).
Change in strength was measured at baseline \& post interventional readings at 6th week.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Sep 2021.
- Background: PubMed 24397371Ardali G. A daily adjustable progressive resistance exercise protocol and functional training to increase quadriceps muscle strength and functional performance in an elderly homebound patient following a total knee arthroplasty. Physiother Theory Pract. 2014 May;30(4):287-97. doi: 10.3109/09593985.2013.868064. Epub 2014 Jan 7.
- Background: PubMed 16558420Wawrzyniak JR, Tracy JE, Catizone PV, Storrow RR. Effect of closed chain exercise on quadriceps femoris peak torque and functional performance. J Athl Train. 1996 Oct;31(4):335-40.
- Background: PubMed 18787253Knight KL. Quadriceps Strengthening with the DAPRE Technique: Case studies with Neurological Implications. J Orthop Sports Phys Ther. 1990;12(2):66-71. doi: 10.2519/jospt.1990.12.2.66.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Rabiya Noor, PhD principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Daily adjustable progressive resistance exercises (DAPRE) and Close kinetic chain exercises (CKC). in people with Extensor Lag and Post-operative Knee Stiffness, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Sep 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in knee functional Improvement by WOMAC index (time frame: 6 weeks (3 sessions per week).). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04790669, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Sep 2021; AzTrials last refreshed its copy on 28 Oct 2026.