SpeechNCT04818021
Contribution of the Somatosensory System to Speech Perceptual Processing
A study testing Perceptual Classification of Speech Sounds and Facial Skin Stretch in people with Speech and Consolidation, run by Yale University at 1 site in Canada.
Trial summary
These studies test the hypothesis that the repeated pairing of somatosensory inputs with speech sounds, such as occurs during speech motor learning, results in changes to the perceptual classification of speech sounds. Read more about this study
- Who is it for?
- Ages 21 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Speech, Consolidation
- What is being tested?
- Perceptual Classification of Speech Sounds and Facial Skin Stretch
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteCanada
- Study dates
- 1 Aug 2019to 31 Jul 2025
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- right handed adults
- no known physical or neurological abnormalities
Who cannot join
- patients with:
- cardiac pacemaker
- surgical clips or values on the heart
- implants
- metal or metallic fragments in any part of the body
- pregnancy
Show all 11Show fewer
- claustrophobia
- a personal or family history of epilepsy
- currently taking antipsychotic drugs
- currently taking antidepressant drugs
- currently taking antianxiety drugs.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Contribution of the Somatosensory System to Speech Perceptual Processing Aim 3
These studies test the hypothesis that the repeated pairing of somatosensory inputs with speech sounds, such as occurs during speech motor learning, results in changes to the perceptual classification of speech sounds.
Read the detailed description
This study will assess changes to the perceptual classification of speech sounds that are related to repeated pairing of somatosensory and auditory inputs (as would occur during speech motor learning). Before and after the training, base-line and post-training auditory perceptual performance will be examined in the absence of somatosensory stimulation, in order to evaluate the effects of the pairing on speech perception. Perceptual classification will be assessed on a 7 point continuum.
- Conditions
- Speech, Consolidation
- Being tested
- Perceptual Classification of Speech Sounds, Facial Skin Stretch
- Medical subject headings
- Speech
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Perceptual Classification of Speech SoundsBehavioural
Perceptual Classification of Speech Sounds
Facial Skin StretchBehavioural
Facial skin stretch
| Study group | Role | What they receive |
|---|---|---|
| Perceptual Judgement with Skin Stretch | Experimental | Perceptual Judgement with Skin Stretch Receives: Behavioral: Perceptual Classification of Speech Sounds; Behavioral: Facial Skin Stretch |
| Perceptual Judgement Control without Skin Stretch | Experimental | Perceptual Judgement Control without Skin Stretch Receives: Behavioral: Perceptual Classification of Speech Sounds |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mean Change in Perception Judgement
Change in perceptual threshold of which words participants heard when presented with different options on a synthetic acoustic 7 point interval scale continuum. Higher means indicate a greater change in auditory perception following the pairing of sounds and facial skin stretch. Score range 0-7
Measured: Baseline and at the end of training (30 minute session)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Mar 2021
- Study start1 Aug 2019
- Primary completion31 Jul 2025
- Study completion31 Jul 2025
Why it stopped: End of funding
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Other trials for SpeechStudies of the same condition, open and under way.
- More trials run by Yale UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Yale University
- Sponsor type
- University, hospital or other
- Collaborators
- McGill University, National Institute on Deafness and Other Communication Disorders (NIDCD)
- Responsible party
- Sponsor
- Investigators
- David Ostry, Principal investigator, Haskins Laboratories
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04818021
- Sponsor's protocol ID
- 2000025475_b
- Other IDs
- R01DC017439
- Status last verified
- Sep 2026
- First submitted
- 19 Mar 2021
- Last updated
- 28 Sep 2026
- Results posted
- Yes, on ClinicalTrials.gov
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Contribution of the Somatosensory System to Speech Perceptual Processing Aim 3
- ClinicalTrials.gov ID
- NCT04818021
- Acronym / sponsor ID
- 2000025475_b
- Conditions
- Speech, Consolidation
- Study type
- Interventional
- Recruitment status
- TerminatedReason stopped: End of funding
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Yale UniversityUniversity, hospital or other
- Collaborators
- McGill University, National Institute on Deafness and Other Communication Disorders (NIDCD)
- Study start
- 1 Aug 2019 (actual)
- Primary completion
- 31 Jul 2025 (actual)
- Study completion
- 31 Jul 2025 (actual)
- First posted
- 26 Mar 2021 (actual)
- Results
- Posted 28 Sep 2026
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
These studies test the hypothesis that the repeated pairing of somatosensory inputs with speech sounds, such as occurs during speech motor learning, results in changes to the perceptual classification of speech sounds.
Detailed description
This study will assess changes to the perceptual classification of speech sounds that are related to repeated pairing of somatosensory and auditory inputs (as would occur during speech motor learning). Before and after the training, base-line and post-training auditory perceptual performance will be examined in the absence of somatosensory stimulation, in order to evaluate the effects of the pairing on speech perception. Perceptual classification will be assessed on a 7 point continuum.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Perceptual Judgement with Skin Stretch | Experimental | Behavioral: Perceptual Classification of Speech Sounds, Behavioral: Facial Skin StretchPerceptual Judgement with Skin Stretch |
| Perceptual Judgement Control without Skin Stretch | Experimental | Behavioral: Perceptual Classification of Speech SoundsPerceptual Judgement Control without Skin Stretch |
Who may qualify
- Ages
- 21 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- right handed adults
- no known physical or neurological abnormalities
Key exclusion criteria (11 listed)
- patients with:
- cardiac pacemaker
- surgical clips or values on the heart
- implants
- metal or metallic fragments in any part of the body
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Perceptual Classification of Speech SoundsPerceptual Classification of Speech Sounds | Behavioural | Perceptual Judgement Control without Skin Stretch, Perceptual Judgement with Skin Stretch |
| Facial Skin StretchFacial skin stretch | Behavioural | Perceptual Judgement with Skin Stretch |
Primary outcome
Mean Change in Perception Judgement
Time frame: Baseline and at the end of training (30 minute session)
Change in perceptual threshold of which words participants heard when presented with different options on a synthetic acoustic 7 point interval scale continuum. Higher means indicate a greater change in auditory perception following the pairing of sounds and facial skin stretch. Score range 0-7
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Sep 2026.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
David Ostry principal investigator
Haskins Laboratories
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Perceptual Classification of Speech Sounds and Facial Skin Stretch in people with Speech and Consolidation, run by Yale University at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 28 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 28 Sep 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mean Change in Perception Judgement (time frame: Baseline and at the end of training (30 minute session)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Sep 2026.