Cohort StudyNTCMRCNCT04839796
Northeastern Taiwan Community Medicine Research Cohort
An observational study of Cohort Study, run by Chang Gung Memorial Hospital at 1 site in Taiwan.
Trial summary
The cohort study on disease prevention and health promotion in the northeastern region of Taiwan is a trial dedicated to large-scale generational research in northeastern Taiwan beginning in the August of 2013. Read more about this study
- Who is it for?
- Ages 20 years and older
- Conditions the study is for
- Cohort Study
- How many people
- 20,000 participants
- Where
- 1 siteTaiwan
- Study dates
- Aug 2013to Aug 2043
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- Adult, Older adult
Study population: Participants who enroll in these community health activities and meet the following conditions: 1. Over the age of 20. 2. Residing in 64 administrative areas in Keelung city and new Taipei city.
Who may be able to join
- Residing in Keelung city and new Taipei city.
- Mobile health and mental health
- Participating in healthcare outreaches
Who cannot join
- Under 20 years old
- Participant without judgment
- Participant has HIV
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan1 site, 1 recruiting
- Recruiting
Community Medicine Research Center Chang Gung Memorial Hospital Keelung,Taiwan,204
Keelung
Yu Chiau Shyu, PHD, 02-24329292 ext. 3391, yuchiaushyu@gmail.com
Rou Ling Cho, PHD, 02-24329292 ext. 3391, royeariel760918@gmail.com
About this study
Official title: A Cohort Study on Disease Prevention and Health Promotion in Northeastern Region of Taiwan
The cohort study on disease prevention and health promotion in the northeastern region of Taiwan is a trial dedicated to large-scale generational research in northeastern Taiwan beginning in the August of 2013. The program aims to develop a comprehensive and integrated approach to disease prevention and community health. The researcher's cohort organizes healthcare outreaches for participants over the age of 20 residing in 64 administrative areas in Keelung city and new Taipei city. The researcher's sessions include a comprehensive health examination, health-related questionnaires, and disease awareness seminars.
Biological samples, questionnaire information, and medical data obtained from researcher's participants are stored in researcher's core laboratory. Depersonalized data and samples are shared with partnering trials approved by the Chang Gung Memorial Hospital Institutional review board. The investigators are currently partnered with 18 clinical trials spanning across multiple disciplines such as urology, hepatology, metabolism, physical therapy, and psychology.
Read the detailed description
The cohort study on disease prevention and health promotion in the northeastern region of Taiwan is a trial dedicated to large-scale generational research in northeastern Taiwan beginning in the August of 2013. The program aims to develop a comprehensive and integrated approach to disease prevention and community health. The researcher's cohort organizes healthcare outreaches for participants over the age in Keelung city and new Taipei city. The researcher's sessions include a comprehensive health examination, health-related questionnaires and disease awareness seminars.
Biological samples, questionnaire information, and medical data obtained from the researcher's participants are stored in the researcher's core laboratory. Depersonalized data and samples are shared with partnering trials approved by the Chang Gung Memorial Hospital Institutional review board. The investigators are currently partnered with 18 clinical trials spanning across multiple disciplines such as urology, hepatology, metabolism, physical therapy, and psychology.
The investigators are also a member of the national "Establish Multi-omics Database of Smart Healthcare for Obesity Therapeutics involving " joint project and the national "Remote Medical Monitoring System-Linking Healthcare Industrial Ecosystem-Taiwanese Novel Disease Monitoring Solution" initiative.
Introduction: This research is conducted in the form of community health care activities. Through regular community health household activities, community residents' awareness of health is improved, and various pathogenic factors are analyzed to strengthen health education, improve living habits, reduce risk factors, and promote the health of community residents.
Project purpose: In order to promote community fitness, The investigators will conduct long-term community medicine generation research. This research consists of a series of collaborative projects such as chronic kidney disease, chronic liver disease, metabolic syndrome, depression, dementia, obesity, exercise rehabilitation, etc.
In community health care activities, collect biological samples such as blood, urine, feces, etc., as well as questionnaire data. This project will link participants relevant health data to establish a database for the generation of Keelung Chang Gung community medicine research. These data will be provided for analysis of co-operative plans related to generations of research and long-term tracking of participants health.
- Conditions
- Cohort Study
- Keywords
- NTCMRC, Maintenance Project, Health Care Activities
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Participants residing in urban areas | Urban residents enjoy convenient transportation, have access to abundant medical resources, have more job opportunities, and are on average younger but are also exposed to more air pollution. | |
| Participants residing in rural areas | Rural residents have less access to transportation, medical resources, and job prospects comparatively and are comparatively older. However, Rural residents are exposed to less pollution in general. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Participant died during the observation period.
Investigators keep in touch with participants and invite them to participate in healthcare outreaches every year.
Measured: From 2013 Augus to Feb 2021
Dementia
The AD8 dementia screening interview is used to detect the early signs of dementia. Using the items in the form to check whether participants have similar symptoms, so as to detect and treat them as soon as possible.
Measured: From 2013 Augus to Feb 2021
Chronic Kidney Disease
Chronic kidney disease is a type of kidney disease in which there is gradual loss of kidney function over a period of months to years.
Measured: From 2013 Augus to Feb 2021
Liver cancer
Participant suffers from liver cancer
Measured: From 2013 Augus to Feb 2021
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Apr 2021
- Study startAug 2013
- Primary completionAug 2043 (estimated)
- Study completionAug 2043 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Cohort StudyStudies of the same condition, open and under way.
- More trials run by Chang Gung Memorial HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 20,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Chang Gung Memorial Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Yu Chiau Shyu, PHD, Principal investigator, Community Medicine Research Center,Chang Gung Memorial Hospital,Keelung branch
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04839796
- Sponsor's protocol ID
- 201800289A3
- Acronym
- NTCMRC
- Status last verified
- Jan 2021
- First submitted
- 28 Mar 2021
- Last updated
- 9 Apr 2021
- Results posted
- No
- Individual data sharing
- No
Publications
Hsu PW, Yeh CH, Lo CJ, Tsai TH, Chan YH, Chou YJ, Yang NI, Cheng ML, Sheu WH, Lai CC, Sytwu HK, Tsai TF. Trans-omics analyses identify the biochemical network of LPCAT1 associated with coronary artery disease. Biomark Res. 2025 Aug 20;13(1):107. doi: 10.1186/s40364-025-00821-y.
PubMed 40830908Wei YC, Chen CK, Lin C, Shyu YC, Chen PY. Life After Traumatic Brain Injury: Effects on the Lifestyle and Quality of Life of Community-Dwelling Patients. Neurotrauma Rep. 2024 Mar 1;5(1):159-171. doi: 10.1089/neur.2023.0113. eCollection 2024.
PubMed 38463415Wu IW, Tsai TH, Lo CJ, Chou YJ, Yeh CH, Cheng ML, Lai CC, Sytwu HK, Tsai TF. Discovery of a Biomarker Signature That Reveals a Molecular Mechanism Underlying Diabetic Kidney Disease via Organ Cross Talk. Diabetes Care. 2022 Jun 2;45(6):e102-e104. doi: 10.2337/dc22-0145. No abstract available.
PubMed 35546525
Study at a glance
From the registry record, last updated by the sponsor on 9 Apr 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Cohort Study on Disease Prevention and Health Promotion in Northeastern Region of Taiwan
- ClinicalTrials.gov ID
- NCT04839796
- Acronym / sponsor ID
- NTCMRC / 201800289A3
- Conditions
- Cohort Study
- Keywords
- NTCMRC, Maintenance Project, Health Care Activities
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 20,000 participants (estimated)
- Lead sponsor
- Chang Gung Memorial HospitalUniversity, hospital or other
- Study start
- Aug 2013 (actual)
- Primary completion
- Aug 2043 (estimated)
- Study completion
- Aug 2043 (estimated)
- First posted
- 9 Apr 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The cohort study on disease prevention and health promotion in the northeastern region of Taiwan is a trial dedicated to large-scale generational research in northeastern Taiwan beginning in the August of 2013. The program aims to develop a comprehensive and integrated approach to disease prevention and community health. The researcher's cohort organizes healthcare outreaches for participants over the age of 20 residing in 64 administrative areas in Keelung city and new Taipei city. The researcher's sessions include a comprehensive health examination, health-related questionnaires, and disease awareness seminars.
Biological samples, questionnaire information, and medical data obtained from researcher's participants are stored in researcher's core laboratory. Depersonalized data and samples are shared with partnering trials approved by the Chang Gung Memorial Hospital Institutional review board. The investigators are currently partnered with 18 clinical trials spanning across multiple disciplines such as urology, hepatology, metabolism, physical therapy, and psychology.
Detailed description
The cohort study on disease prevention and health promotion in the northeastern region of Taiwan is a trial dedicated to large-scale generational research in northeastern Taiwan beginning in the August of 2013. The program aims to develop a comprehensive and integrated approach to disease prevention and community health. The researcher's cohort organizes healthcare outreaches for participants over the age in Keelung city and new Taipei city. The researcher's sessions include a comprehensive health examination, health-related questionnaires and disease awareness seminars.
Biological samples, questionnaire information, and medical data obtained from the researcher's participants are stored in the researcher's core laboratory. Depersonalized data and samples are shared with partnering trials approved by the Chang Gung Memorial Hospital Institutional review board. The investigators are currently partnered with 18 clinical trials spanning across multiple disciplines such as urology, hepatology, metabolism, physical therapy, and psychology.
The investigators are also a member of the national "Establish Multi-omics Database of Smart Healthcare for Obesity Therapeutics involving " joint project and the national "Remote Medical Monitoring System-Linking Healthcare Industrial Ecosystem-Taiwanese Novel Disease Monitoring Solution" initiative.
Introduction: This research is conducted in the form of community health care activities. Through regular community health household activities, community residents' awareness of health is improved, and various pathogenic factors are analyzed to strengthen health education, improve living habits, reduce risk factors, and promote the health of community residents.
Project purpose: In order to promote community fitness, The investigators will conduct long-term community medicine generation research. This research consists of a series of collaborative projects such as chronic kidney disease, chronic liver disease, metabolic syndrome, depression, dementia, obesity, exercise rehabilitation, etc.
In community health care activities, collect biological samples such as blood, urine, feces, etc., as well as questionnaire data. This project will link participants relevant health data to establish a database for the generation of Keelung Chang Gung community medicine research. These data will be provided for analysis of co-operative plans related to generations of research and long-term tracking of participants health.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Participants residing in urban areas | – | –Urban residents enjoy convenient transportation, have access to abundant medical resources, have more job opportunities, and are on average younger but are also exposed to more air pollution. |
| Participants residing in rural areas | – | –Rural residents have less access to transportation, medical resources, and job prospects comparatively and are comparatively older. However, Rural residents are exposed to less pollution in general. |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- Participants who enroll in these community health activities and meet the following conditions: 1. Over the age of 20. 2. Residing in 64 administrative areas in Keelung city and new Taipei city.
Key inclusion criteria (3 listed)
- Residing in Keelung city and new Taipei city.
- Mobile health and mental health
- Participating in healthcare outreaches
Key exclusion criteria (3 listed)
- Under 20 years old
- Participant without judgment
- Participant has HIV
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Participant died during the observation period.
Time frame: From 2013 Augus to Feb 2021
Investigators keep in touch with participants and invite them to participate in healthcare outreaches every year.
Dementia
Time frame: From 2013 Augus to Feb 2021
The AD8 dementia screening interview is used to detect the early signs of dementia. Using the items in the form to check whether participants have similar symptoms, so as to detect and treat them as soon as possible.
Chronic Kidney Disease
Time frame: From 2013 Augus to Feb 2021
Chronic kidney disease is a type of kidney disease in which there is gradual loss of kidney function over a period of months to years.
Liver cancer
Time frame: From 2013 Augus to Feb 2021
Participant suffers from liver cancer
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Apr 2021.
- Derived from this study: PubMed 40830908Hsu PW, Yeh CH, Lo CJ, Tsai TH, Chan YH, Chou YJ, Yang NI, Cheng ML, Sheu WH, Lai CC, Sytwu HK, Tsai TF. Trans-omics analyses identify the biochemical network of LPCAT1 associated with coronary artery disease. Biomark Res. 2025 Aug 20;13(1):107. doi: 10.1186/s40364-025-00821-y.
- Derived from this study: PubMed 38463415Wei YC, Chen CK, Lin C, Shyu YC, Chen PY. Life After Traumatic Brain Injury: Effects on the Lifestyle and Quality of Life of Community-Dwelling Patients. Neurotrauma Rep. 2024 Mar 1;5(1):159-171. doi: 10.1089/neur.2023.0113. eCollection 2024.
- Derived from this study: PubMed 35546525Wu IW, Tsai TH, Lo CJ, Chou YJ, Yeh CH, Cheng ML, Lai CC, Sytwu HK, Tsai TF. Discovery of a Biomarker Signature That Reveals a Molecular Mechanism Underlying Diabetic Kidney Disease via Organ Cross Talk. Diabetes Care. 2022 Jun 2;45(6):e102-e104. doi: 10.2337/dc22-0145. No abstract available.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Yu Chiau Shyu, PHD principal investigator
Community Medicine Research Center,Chang Gung Memorial Hospital,Keelung branch
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cohort Study, run by Chang Gung Memorial Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 9 Apr 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Yu Chiau Shyu, PHD (02-24329292 ext. 3391, yuchiaushyu@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Participant died during the observation period. (time frame: From 2013 Augus to Feb 2021). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04839796, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Apr 2021.