Smoking CessationNCT04893460

CoQuit Study for Smoking Cessation

A study testing CoQuit App in people with Smoking Cessation, run by Oregon Research Behavioral Intervention Strategies, Inc. at 1 site in United States.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

Who is it for?: Ages 18 years and older
Conditions the study is for: Smoking Cessation
What is being tested?: CoQuit App
Type of treatment: Lifestyle or therapy programme
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 72 participants
Where: 1 siteUnited States
Study dates: 1 Jun 2021to 29 Sep 2021
Phase: Interventional
Are there results?: Yes, posted in the registrySummary in the doctors' view

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 years and older
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

Age 18 or older
Self-reported daily smoking
Having a valid home mailing address
English speaking
Access to a smart phone with video capability and internet
Expressed desire to quit smoking

Who cannot join

Currently participating in any tobacco cessation programs

Trial locations and contacts

1 site in 1 country.

United States1 site

ORBIS/Oregon Research Institute
Springfield, Oregon, 97477

Other trials in United States

About this study

Official title: A Mobile App Based Cognitive Dissonance Intervention for Smoking Cessation

This study investigated the feasibility of a cognitive dissonance-based mobile app for smoking cessation (CDI). Cognitive dissonance refers to the conflict between beliefs and behaviors; interventions are designed to promote this conflict to motivate people to change their behavior. Recent research has demonstrated the efficacy and potential of using cognitive dissonance interventions for a wide range of health and behavioral problems including smoking cessation. This study developed an initial version of the CDI mobile app and evaluated the app in an evaluation study with 60 adult smokers.

Read the detailed description

An initial version of the CoQuit app was developed and tested with 60 adult smokers. All participants were recruited through social media and were screened and consented online. After enrolling, participants received a link to the baseline survey which asked about past and current tobacco use, nicotine dependence, motivation to quit, cognitive dissonance and demographic information. All participants were assigned to an online support group of 5 or 6 people. The group received simultaneous invites to the app so they were able to move through the 25 day program together. The app contained short videos of a CoQuit facilitator who presented instructions for specific tasks, such as writing a brief letter to a friend or family member explaining their commitment to stop smoking. Participants recorded videos of themselves related to these activities and posted the videos within the app where they were viewed by other members of the group. All participants completed a six weeks post baseline online assessment asking about past and current tobacco use, quit attempts, as well as feedback on usability and possible improvements to the app.

Conditions: Smoking Cessation
Being tested: CoQuit App
Medical subject headings: Smoking Cessation

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

CoQuit AppBehavioural
The CoQuit App is a cognitive dissonance based app for smoking cessation.

Study groups in NCT04893460
Study group	Role	What they receive
Intervention	Experimental	All participants will use the CoQuit App for Smoking Cessation Receives: Behavioral: CoQuit App

What is being measured

The primary outcome is the main question the study is designed to answer.

Cognitive Dissonance
Participants were asked to give a "gut-level response" to 14 words used to describe various attributes of cognitive dissonance (e.g., uncomfortable, shame). Response options for each attribute were on a 7-point scale (1 = does not apply at all, 7 = applies very much). A mean score was computed across all 14 words. A higher score was associated with greater levels of cognitive dissonance. In addition to the baseline and six-week follow-up assessment of cognitive dissonance, participants were asked five times during the 25 days of using the app. The five times were after completing the "Costs" activity on day 3, the "Quit Letter" activity on day 6, the "Planning for Pitfalls" activity on day 10, the "Staying Smoke Free" activity on day 14, and the "Letter to Youth" activity on day 19.
Measured: Baseline, 5 times during app use (days 3, 6, 10, 14 and 19 of the 25 day program), Six weeks post baseline
Number of Participants With Number Cigarettes Smoked Per Day
A one-item question that asked about the number of cigarettes smoked per day. Response options were on a 6-point scale, where 1 = 5 or less, 2 = 6-10, 3 = 11-15, 4 = 16-20, 5 = 21-30, and 6 = 31 or more. A higher score indicates a greater number of cigarettes smoked per day.
Measured: Baseline and Six Weeks Post Baseline

Secondary outcomes (1)

Readiness to Quit
Participants were asked to rate what best describes how they currently think about quitting smoking. The one item had a 1-point scale (0 = I have no thought about quitting smoking, 2 = I think I need to consider quitting smoking someday, 5 = I think I should quit smoking, but I am not quite ready, 8 = I am starting to think about how to reduce the number of cigarettes I smoke a day, 10 = I am taking action to quit smoking, 11 = I have stopped smoking). A higher score was associated with greater readiness to quit smoking. In addition to the baseline and six-week follow-up assessment of readiness to quit, participants were asked five times during the 25 days of using the app. The five times were after completing the "Costs" activity on day 3, the "Quit Letter" activity on day 6, the "Planning for Pitfalls" activity on day 10, the "Staying Smoke Free" activity on day 14, and the "Letter to Youth" activity on day 19.
Measured: Baseline, 5 times during app use (days 3, 6, 10, 14 and 19 of the 25 day program), Six weeks post baseline

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1 Jun 202129 Sep 2021

First posted19 May 2021
Study start1 Jun 2021
Primary completion29 Sep 2021
Study completion29 Sep 2021

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
Other trials for Smoking CessationStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Enrolment: 72 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT04893460
Sponsor's protocol ID: DP006495-01
Status last verified: Aug 2025
First submitted: 14 May 2021
Last updated: 4 Sep 2025
Results posted: Yes, on ClinicalTrials.gov
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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All Smoking Cessation trials

Study at a glance

From the registry record, last updated by the sponsor on 4 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: A Mobile App Based Cognitive Dissonance Intervention for Smoking Cessation
ClinicalTrials.gov ID: NCT04893460
Acronym / sponsor ID: DP006495-01
Conditions: Smoking Cessation
Study type: Interventional
Recruitment status: Completed
Enrolment: 72 participants (actual)
Lead sponsor: Oregon Research Behavioral Intervention Strategies, Inc.Industry (pharma, biotech, devices)
Study start: 1 Jun 2021 (actual)
Primary completion: 29 Sep 2021 (actual)
Study completion: 29 Sep 2021 (actual)
First posted: 19 May 2021 (actual)
Results: Posted 4 Sep 2025

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Detailed description

Study design

Primary purpose: Treatment
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Number of arms: 1

Arm	Type	Receives
Intervention	Experimental	Behavioral: CoQuit AppAll participants will use the CoQuit App for Smoking Cessation

Who may qualify

Ages: 18 years and older
Sex: All
Healthy volunteers: Not accepted
Age groups: Adult, Older adult

Key inclusion criteria (6 listed)

Age 18 or older
Self-reported daily smoking
Having a valid home mailing address
English speaking
Access to a smart phone with video capability and internet

Key exclusion criteria (1 listed)

Currently participating in any tobacco cessation programs

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
CoQuit AppThe CoQuit App is a cognitive dissonance based app for smoking cessation.	Behavioural	Intervention

Primary outcome

Cognitive Dissonance
Time frame: Baseline, 5 times during app use (days 3, 6, 10, 14 and 19 of the 25 day program), Six weeks post baseline
Participants were asked to give a "gut-level response" to 14 words used to describe various attributes of cognitive dissonance (e.g., uncomfortable, shame). Response options for each attribute were on a 7-point scale (1 = does not apply at all, 7 = applies very much). A mean score was computed across all 14 words. A higher score was associated with greater levels of cognitive dissonance. In addition to the baseline and six-week follow-up assessment of cognitive dissonance, participants were asked five times during the 25 days of using the app. The five times were after completing the "Costs" activity on day 3, the "Quit Letter" activity on day 6, the "Planning for Pitfalls" activity on day 10, the "Staying Smoke Free" activity on day 14, and the "Letter to Youth" activity on day 19.
Number of Participants With Number Cigarettes Smoked Per Day
Time frame: Baseline and Six Weeks Post Baseline
A one-item question that asked about the number of cigarettes smoked per day. Response options were on a 6-point scale, where 1 = 5 or less, 2 = 6-10, 3 = 11-15, 4 = 16-20, 5 = 21-30, and 6 = 31 or more. A higher score indicates a greater number of cigarettes smoked per day.

1 secondary outcome

Readiness to Quit
Time frame: Baseline, 5 times during app use (days 3, 6, 10, 14 and 19 of the 25 day program), Six weeks post baseline

Results and safety

Results posted to the registry on 4 Sep 2025, as reported by the sponsor. Figures are copied from the record, not re-analysed. Full results on ClinicalTrials.gov.

Participant flow

Group	Started	Completed
Intervention	72	54

Primary outcome: Cognitive Dissonance

Time frame: Baseline, 5 times during app use (days 3, 6, 10, 14 and 19 of the 25 day program), Six weeks post baseline. Mean (Standard Deviation). Unit: units on a scale

Measure	Intervention n = 54
Baseline	2.23 (1.23)
In app 1 - After Costs Activity	3.32 (1.43)
In app 2 - After Quit Letter Activity	4.33 (1.48)
In app 3 - After Pitfalls Activity	3.67 (1.76)
In app 4 - After Smoke Free Activity	3.14 (1.83)
In app 5 - After Letter to Youth Activity	3.69 (1.89)
6 Weeks Post Baseline	2.48 (1.34)

Intervention: Mean Difference (Final Values): -1.09, p = .003, t-test, 2 sided
Intervention: Mean Difference (Final Values): -2.10, p <.001, t-test, 2 sided
Intervention: Mean Difference (Final Values): -1.44, p = .004, t-test, 2 sided

Population analysed: Due to conceptual concerns about imputing smoking status, decreases in smoking from pretest to posttest were evaluated with participants who completed both the pretest and posttest assessment

Primary outcome: Number of Participants With Number Cigarettes Smoked Per Day

Time frame: Baseline and Six Weeks Post Baseline. Count of participants. Unit: Participants

Measure	Intervention n = 46
Baseline: 5 or less	0
Baseline: 6-10	12
Baseline: 11-15	13
Baseline: 16-20	10
Baseline: 21-30	11
Baseline: 31 or more	0
6 Weeks Post Baseline: 5 or less	13
6 Weeks Post Baseline: 6-10	16

Intervention: median pairwise average: 17.67, p <.001, Wilcoxson Signed Rank Test

Population analysed: Due to conceptual concerns about imputing smoking status, decreases in smoking from pretest to posttest was evaluated with participants who completed both the pretest and posttest number of cigarettes smoked item.

1 secondary outcome is reported in the full results.

Adverse events

Time frame: 6 weeks. Other adverse events reported at 0% frequency or more

Group	Serious adverse events	Other adverse events	Deaths
Intervention	0 of 72 (0%)	0 of 72 (0%)	0 of 72

Loading the posted results from ClinicalTrials.gov…

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 4 Sep 2025.
Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
Individual participant dataSharing planned: No

Related trials for Smoking Cessation

Recruiting
Smoking Cessation in Patients With Cancer
Cancer, Tobacco Use
Enrolling by invitationObservational study
Using Smartwatches to Monitor Smoking in Real-life Situations
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Effectiveness Of Project EX: A Classroom-Based Smoking Prevention And Cessation Intervention Program
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Recruiting
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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Dana Smith, PhD principal investigator

Influents Innovations/Oregon Research Institute

Herb Severson, PhD principal investigator

Influents Innovations/Oregon Research Institute

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing CoQuit App in people with Smoking Cessation, run by Oregon Research Behavioral Intervention Strategies, Inc. at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 4 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Yes. Results are posted in the registry (first posted 4 Sep 2025). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Cognitive Dissonance (time frame: Baseline, 5 times during app use (days 3, 6, 10, 14 and 19 of the 25 day program), Six weeks post baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT04893460.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Sep 2025.