VapingNCT04919590
Text Message Quit Vaping Intervention for Adolescents
A study testing This is Quitting in people with Vaping and Cessation, Tobacco, run by Truth Initiative at 1 site in United States.
Trial summary
This research study, conducted by Truth Initiative, will help us learn how text messaging can help adolescents between 13 and 17 years of age quit vaping. Read more about this study
- Who is it for?
- Ages 13 to 17 yearsHealthy volunteers can take part
- Conditions the study is for
- Vaping, Cessation, Tobacco
- What is being tested?
- This is Quitting
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,681 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Oct 2021to 18 Oct 2023
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 to 17 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
- Age 13-17
- Past 30-day use of e-cigarettes containing nicotine
- Interest in quitting e-cigarette use in the next 30 days
- US residence
Who cannot join
- Failure to confirm mobile number after initial sign-up
Trial locations and contacts
1 site in 1 country.
United States1 site
Truth Initiative
Washington D.C., District of Columbia, 20001
About this study
This research study, conducted by Truth Initiative, will help us learn how text messaging can help adolescents between 13 and 17 years of age quit vaping.
Read the detailed description
The Teen Quit Vaping Study (QVS Teen) is a comparative effectiveness trial to evaluate the effectiveness of a quit vaping text message program in promoting abstinence from e-cigarettes among young users aged 13-17. This study is a 3-arm randomized controlled trial conducted among young users aged 13-17 recruited through online channels. Participants will be randomized to a quit vaping text message intervention, an assessment-only control condition, or a waitlist control condition. The primary aim is to examine 30-day point prevalence abstinence at 7-months post enrollment (roughly corresponds to 6-months post-treatment).
- Conditions
- Vaping, Cessation, Tobacco
- Being tested
- This is Quitting, Assessment only control, Waitlist control
- Keywords
- Vaping cessation, Mobile intervention, Adolescents
- Medical subject headings
- Vaping, Tobacco Use Cessation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
This is QuittingBehavioural
Text message-based intervention for quit vaping support.
Assessment only controlOther
Assessment only
Waitlist controlOther
No contact until follow-up survey, waitlisted to receive intervention post study
| Study group | Role | What they receive |
|---|---|---|
| This is Quitting | Experimental | Participants will be enrolled to receive messages from This is Quitting.
Users receive one age-appropriate message per day tailored to their enrollment date or quit date, which can be set and reset via text message. Those not ready to quit receive 4 weeks of messages focused on building skills and confidence. Users who set a quit date receive messages for a week preceding it and 8 weeks afterward that include encouragement and support, skill- and self-efficacy building exercises, coping strategies, and information about the risks of vaping, benefits of quitting, and cutting down to quit. Keywords COPE, STRESS, SLIP, and MORE provide on-demand support. Receives: Behavioral: This is Quitting |
| Assessment only control | Other | After an initial enrollment message, participants will be contacted monthly to assess e-cigarette use. At the end of the study data collection period, they will receive information on how to sign up for This is Quitting if they are interested in the program. Receives: Other: Assessment only control |
| Waitlist control | Other | After an initial enrollment message, participants will receive no contact from study staff except for 1-month and 7-month follow-up assessments. At the end of the study data collection period, they will receive information on how to sign up for This is Quitting if they are interested in the program. Receives: Other: Waitlist control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Self-reported 30-day Point Prevalence Abstinence
In the past 30 days, did you vape at all, even a puff of someone else's?
Measured: 7 months post enrollment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jun 2021
- Study start1 Oct 2021
- Primary completion18 Oct 2023
- Study completion18 Oct 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for VapingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 1,681 participants (actual)
Sponsor and investigators
- Lead sponsor
- Truth Initiative
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04919590
- Sponsor's protocol ID
- TruthInitiativeQVSTeen
- Status last verified
- Feb 2025
- First submitted
- 4 Jun 2021
- Last updated
- 12 Mar 2025
- Results posted
- Yes, on ClinicalTrials.gov
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: IPD are not available to other researchers. For access to deidentified dataset, please contact study administrator for more information.
Publications
Graham AL, Cha S, Jacobs MA, Amato MS, Funsten AL, Edwards G, Papandonatos GD. A Vaping Cessation Text Message Program for Adolescent E-Cigarette Users: A Randomized Clinical Trial. JAMA. 2024 Sep 3;332(9):713-721. doi: 10.1001/jama.2024.11057.
PubMed 39110436Graham AL, Cha S, Do EK, Jacobs MA, Edwards G, Papandonatos GD. Dual abstinence from nicotine vaping and cannabis use among young people: secondary analyses from two U.S.-based randomized controlled trials of vaping cessation. Subst Abuse Treat Prev Policy. 2025 Nov 3;20(1):48. doi: 10.1186/s13011-025-00679-1.
PubMed 41177894
Study at a glance
From the registry record, last updated by the sponsor on 12 Mar 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Text Message Quit Vaping Intervention for Adolescents
- ClinicalTrials.gov ID
- NCT04919590
- Acronym / sponsor ID
- TruthInitiativeQVSTeen
- Conditions
- Vaping, Cessation, Tobacco
- Keywords
- Vaping cessation, Mobile intervention, Adolescents
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 1,681 participants (actual)
- Lead sponsor
- Truth InitiativeUniversity, hospital or other
- Study start
- 1 Oct 2021 (actual)
- Primary completion
- 18 Oct 2023 (actual)
- Study completion
- 18 Oct 2023 (actual)
- First posted
- 9 Jun 2021 (actual)
- Results
- Posted 12 Mar 2025
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This research study, conducted by Truth Initiative, will help us learn how text messaging can help adolescents between 13 and 17 years of age quit vaping.
Detailed description
The Teen Quit Vaping Study (QVS Teen) is a comparative effectiveness trial to evaluate the effectiveness of a quit vaping text message program in promoting abstinence from e-cigarettes among young users aged 13-17. This study is a 3-arm randomized controlled trial conducted among young users aged 13-17 recruited through online channels. Participants will be randomized to a quit vaping text message intervention, an assessment-only control condition, or a waitlist control condition. The primary aim is to examine 30-day point prevalence abstinence at 7-months post enrollment (roughly corresponds to 6-months post-treatment).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| This is Quitting | Experimental | Behavioral: This is QuittingParticipants will be enrolled to receive messages from This is Quitting. Users receive one age-appropriate message per day tailored to their enrollment date or quit date, which can be set and reset via text message. Those not ready to quit receive 4 weeks of messages focused on building skills and confidence. Users who set a quit date receive messages for a week preceding it and 8 weeks afterward that include encouragement and support, skill- and self-efficacy building exercises, coping strategies, and information about the risks of vaping, benefits of quitting, and cutting down to quit. Keywords COPE, STRESS, SLIP, and MORE provide on-demand support. |
| Assessment only control | Other | Other: Assessment only controlAfter an initial enrollment message, participants will be contacted monthly to assess e-cigarette use. At the end of the study data collection period, they will receive information on how to sign up for This is Quitting if they are interested in the program. |
| Waitlist control | Other | Other: Waitlist controlAfter an initial enrollment message, participants will receive no contact from study staff except for 1-month and 7-month follow-up assessments. At the end of the study data collection period, they will receive information on how to sign up for This is Quitting if they are interested in the program. |
Who may qualify
- Ages
- 13 to 17 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (4 listed)
- Age 13-17
- Past 30-day use of e-cigarettes containing nicotine
- Interest in quitting e-cigarette use in the next 30 days
- US residence
Key exclusion criteria (1 listed)
- Failure to confirm mobile number after initial sign-up
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| This is QuittingText message-based intervention for quit vaping support. | Behavioural | This is Quitting |
| Assessment only controlAssessment only | Other | Assessment only control |
| Waitlist controlNo contact until follow-up survey, waitlisted to receive intervention post study | Other | Waitlist control |
Primary outcome
Self-reported 30-day Point Prevalence Abstinence
Time frame: 7 months post enrollment
In the past 30 days, did you vape at all, even a puff of someone else's?
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Mar 2025.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Background: PubMed 39110436Graham AL, Cha S, Jacobs MA, Amato MS, Funsten AL, Edwards G, Papandonatos GD. A Vaping Cessation Text Message Program for Adolescent E-Cigarette Users: A Randomized Clinical Trial. JAMA. 2024 Sep 3;332(9):713-721. doi: 10.1001/jama.2024.11057.
- Derived from this study: PubMed 41177894Graham AL, Cha S, Do EK, Jacobs MA, Edwards G, Papandonatos GD. Dual abstinence from nicotine vaping and cannabis use among young people: secondary analyses from two U.S.-based randomized controlled trials of vaping cessation. Subst Abuse Treat Prev Policy. 2025 Nov 3;20(1):48. doi: 10.1186/s13011-025-00679-1.
- Individual participant dataSharing planned: No. IPD are not available to other researchers. For access to deidentified dataset, please contact study administrator for more information.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing This is Quitting in people with Vaping and Cessation, Tobacco, run by Truth Initiative at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 12 Mar 2025). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Self-reported 30-day Point Prevalence Abstinence (time frame: 7 months post enrollment). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04919590, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Mar 2025.