Vitamin D DeficiencyNCT04944212
Prevalence of Vitamin D Deficiency in Pregnant Women and Their Fetus in North Jordan
An observational study of Vitamin D Deficiency, run by Jordan University of Science and Technology at 1 site in Jordan.
Trial summary
In Jordan, there are few data about the prevalence of hypovitaminosis D in pregnant women and their newborns and factors that affect their levels. Hence, in this study, investigators will : 1. Determine vitamin D levels among newborns born in north Jordan 2. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Vitamin D Deficiency
- What is being tested?
- Measuring vitamin D serum level using ELIZA
- How many people
- 396 participants
- Where
- 1 siteJordan
- Study dates
- 31 Oct 2021to 30 Jul 2022
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Pregnant women with singleton live fetuses who attended to labour ward
Who may be able to join
- All pregnant women who attend to labour ward with singleton alive pregnancies
Who cannot join
- women with multiple pregnancies or with dead fetuses
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Prevalence of Vitamin D Deficiency in Pregnant Women and Their Newborns and Their Association With Maternal and Newborns Characteristics
In Jordan, there are few data about the prevalence of hypovitaminosis D in pregnant women and their newborns and factors that affect their levels. Hence, in this study, investigators will :
- Determine vitamin D levels among newborns born in north Jordan
- Determine vitamin D levels among pregnant women in north Jordan
- Study the association between maternal and infants levels of vitamin D
- Explore the association between maternal and fetal characteristics and maternal and/or fetal vitamin D level
- Study the effect of low fetal vitamin D on newborn anthropometry
- Study the effect of maternal vitamin D supplement use during pregnancy in raising cord serum vitamin D levels
Read the detailed description
This is a cross-sectional study that will be carried out at King Abdullah University Hospital (KAUH). After being approved by the Institutional Review Board (IRB) of KAUH, written informed consents will be obtained from the newborns' mothers.
5 ml of venous blood will be obtained from pregnant women at the time of admission and 3 ml of venous blood will be obtained from the umbilical cord veins of the newborns immediately after their delivery. The quantitative measurement of 25OHD in serum will be performed using ELIZA.
Investigators will determine the means, medians and standard deviations of 25OHD levels among pregnant women and infants in Jordan. In addition, investigators will study the association between maternal and infants levels of 25OHD. Moreover, investigators will investigate the association between maternal level of vitamin D and elective maternal variables including vitamin D supplements during and before pregnancy, sun exposure, age, weight, parity, BMI, \& maternal medical problems. In addition, investigators will study the effect of low fetal vitamin D on newborn anthropometry. Finally, investigators will study the effect of maternal vitamin D supplements use during pregnancy in raising cord serum vitamin D levels
- Conditions
- Vitamin D Deficiency
- Being tested
- Measuring vitamin D serum level using ELIZA
- Medical subject headings
- Vitamin D Deficiency
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Measuring vitamin D serum level using ELIZADiagnostic test
Venous blood will be obtained from pregnant women at the time of admission and from the umbilical cord veins of the newborns immediately after their delivery. The quantitative measurement of 25OHD in serum will be performed using ELIZA.
What is being measured
The primary outcome is the main question the study is designed to answer.
Determine maternal and fetal vitamin D level among pregnant women and their newborns in north Jordan
Measurement of vitamin D using ELIZA
Measured: 5 minutes
Secondary outcomes (1)
Study the association between maternal and infants levels of vitamin D. Study factors that affect maternal and fetal vitamin D level
Both are measured using ELIZA
Measured: 5 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jun 2021
- Study start31 Oct 2021
- Primary completion30 Jul 2022
- Study completion30 Jul 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Vitamin D DeficiencyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 396 participants (actual)
Sponsor and investigators
- Lead sponsor
- Jordan University of Science and Technology
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Rawan A Obeidat, Dr, Principal investigator, Jordan University of Science and Technology
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04944212
- Sponsor's protocol ID
- 39/131/2020
- Status last verified
- Mar 2023
- First submitted
- 21 Jun 2021
- Last updated
- 10 Mar 2023
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Obeidat RA, Sakee B, Alguzo S, Alshwayyat S, Altal OF, Rawashdeh H. Vitamin D status at birth among pregnant women and their newborns in Jordan: a cross-sectional study. Front Med (Lausanne). 2026 Jun 9;13:1864210. doi: 10.3389/fmed.2026.1864210. eCollection 2026.
PubMed 42344505
Study at a glance
From the registry record, last updated by the sponsor on 10 Mar 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prevalence of Vitamin D Deficiency in Pregnant Women and Their Newborns and Their Association With Maternal and Newborns Characteristics
- ClinicalTrials.gov ID
- NCT04944212
- Acronym / sponsor ID
- 39/131/2020
- Conditions
- Vitamin D Deficiency
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 396 participants (actual)
- Lead sponsor
- Jordan University of Science and TechnologyUniversity, hospital or other
- Study start
- 31 Oct 2021 (actual)
- Primary completion
- 30 Jul 2022 (actual)
- Study completion
- 30 Jul 2022 (actual)
- First posted
- 29 Jun 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In Jordan, there are few data about the prevalence of hypovitaminosis D in pregnant women and their newborns and factors that affect their levels. Hence, in this study, investigators will :
- Determine vitamin D levels among newborns born in north Jordan
- Determine vitamin D levels among pregnant women in north Jordan
- Study the association between maternal and infants levels of vitamin D
- Explore the association between maternal and fetal characteristics and maternal and/or fetal vitamin D level
- Study the effect of low fetal vitamin D on newborn anthropometry
- Study the effect of maternal vitamin D supplement use during pregnancy in raising cord serum vitamin D levels
Detailed description
This is a cross-sectional study that will be carried out at King Abdullah University Hospital (KAUH). After being approved by the Institutional Review Board (IRB) of KAUH, written informed consents will be obtained from the newborns' mothers.
5 ml of venous blood will be obtained from pregnant women at the time of admission and 3 ml of venous blood will be obtained from the umbilical cord veins of the newborns immediately after their delivery. The quantitative measurement of 25OHD in serum will be performed using ELIZA.
Investigators will determine the means, medians and standard deviations of 25OHD levels among pregnant women and infants in Jordan. In addition, investigators will study the association between maternal and infants levels of 25OHD. Moreover, investigators will investigate the association between maternal level of vitamin D and elective maternal variables including vitamin D supplements during and before pregnancy, sun exposure, age, weight, parity, BMI, \& maternal medical problems. In addition, investigators will study the effect of low fetal vitamin D on newborn anthropometry. Finally, investigators will study the effect of maternal vitamin D supplements use during pregnancy in raising cord serum vitamin D levels
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Pregnant women with singleton live fetuses who attended to labour ward
Key inclusion criteria (1 listed)
- All pregnant women who attend to labour ward with singleton alive pregnancies
Key exclusion criteria (1 listed)
- women with multiple pregnancies or with dead fetuses
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Measuring vitamin D serum level using ELIZAVenous blood will be obtained from pregnant women at the time of admission and from the umbilical cord veins of the newborns immediately after their delivery. The quantitative measurement of 25OHD in serum will be performed using ELIZA. | Diagnostic test | – |
Primary outcome
Determine maternal and fetal vitamin D level among pregnant women and their newborns in north Jordan
Time frame: 5 minutes
Measurement of vitamin D using ELIZA
1 secondary outcome
Study the association between maternal and infants levels of vitamin D. Study factors that affect maternal and fetal vitamin D level
Time frame: 5 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Mar 2023.
- Derived from this study: PubMed 42344505Obeidat RA, Sakee B, Alguzo S, Alshwayyat S, Altal OF, Rawashdeh H. Vitamin D status at birth among pregnant women and their newborns in Jordan: a cross-sectional study. Front Med (Lausanne). 2026 Jun 9;13:1864210. doi: 10.3389/fmed.2026.1864210. eCollection 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Rawan A Obeidat, Dr principal investigator
Jordan University of Science and Technology
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Vitamin D Deficiency, run by Jordan University of Science and Technology at 1 site in Jordan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 10 Mar 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Jordan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Determine maternal and fetal vitamin D level among pregnant women and their newborns in north Jordan (time frame: 5 minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04944212, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Mar 2023.