Substance-Related DisorderswebCHATNCT04959461
Preventing Impaired Driving Among Adolescents
A study testing webCHAT in people with Substance-Related Disorders, run by Stanford University at 2 sites in United States.
Trial summary
The primary goal of this project is to evaluate the efficacy of webCHAT, a single-session web-intervention, on reducing impaired driving among adolescents receiving behind-the-wheel training at driver education programs. Read more about this study
- Who is it for?
- Ages 15 to 17 yearsHealthy volunteers can take part
- Conditions the study is for
- Substance-Related Disorders
- What is being tested?
- webCHAT
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 198 participants
- Where
- 2 sitesUnited States
- Study dates
- 1 Jan 2022to 31 Aug 2025
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 15 to 17 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
- 15.5-17 year olds enrolled in driver education school
- Access to a computer or smartphone
- Within one month of taking their driver's licensing exam
Who cannot join
- Under 15.5 or over 17 years old
- Not enrolled in one of the participating schools
- Non-English speaking
Trial locations and contacts
2 sites in 1 country.
United States2 sites
DriveSafe Driving School
Dearborn, Michigan, 48126
DriveSafe Driving School
Denver, Colorado, 80220
About this study
Official title: A Pilot Trial to Prevent Intoxicated and Impaired Driving Among Adolescents
The primary goal of this project is to evaluate the efficacy of webCHAT, a single-session web-intervention, on reducing impaired driving among adolescents receiving behind-the-wheel training at driver education programs.
Read the detailed description
Alcohol and marijuana (AM) are the most commonly used substances among adolescents in the U.S. The consequences of AM use are significantly higher relative to use of either substance alone. This study builds on effective interventions that have demonstrated reductions in alcohol and/or marijuana use and reduced consequences one year later, and proposes to adapt one of those interventions, CHAT, to the web (web-CHAT). The investigators will evaluate the efficacy of web-CHAT among 15.5-17-year-old adolescents (n=150) recruited when teen participants are attending behind-the-wheel training. The study has the potential to promote public welfare by improving adolescent health outcomes and reducing risky driving behaviors that can have substantial monetary and social costs, as well as by providing unique insight into what mediates reduced risky driving attitudes behaviors among those in the intervention. The study is innovative because it is for both youth who are at risk for substance use as well as those who are not, and it is delivered during a teachable moment when adolescents receive driver's education. Finally, this study can provide unique insights about the efficacy of web-CHAT to reduce marijuana initiation, use, and risky driving attitudes in the context of a changing marijuana policy climate. A 3-year study is proposed to test the feasibility of research procedures in a driver education setting and pilot the efficacy of web-CHAT. The investigators will test whether web-CHAT reduces alcohol and/or marijuana initiation or use compared to teens in UC, at three and six-month follow-up.
- Conditions
- Substance-Related Disorders
- Being tested
- webCHAT, Usual Care
- Keywords
- impaired driving
- Medical subject headings
- Substance-Related Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
webCHATBehavioural
A self-guided, single session web intervention that utilizes a motivational interviewing style to prevent impaired driving
Usual CareBehavioural
6 hours of driver education
| Study group | Role | What they receive |
|---|---|---|
| webCHAT | Experimental | Single session 20-40minute self-guided web program that discusses promotes healthy decision making around driving and discusses the risks of alcohol and cannabis-influenced driving. Receives: Behavioral: webCHAT |
| Usual Care | Active comparator | Existing driving school education Receives: Behavioral: Usual Care |
What is being measured
The primary outcome is the main question the study is designed to answer.
Alcohol and/or Cannabis Use
Total number of participants who self-reported an increased frequency of using the specified substance or substance combination in the past 3 months at 3- and/or 6-month-follow-up when compared to baseline, as denoted by a binary variable (1 = increased frequency; 0 = maintained or decreased frequency)
Measured: Baseline through 6-month-follow-up
Secondary outcomes (3)
Driving Under the Influence
Number and percentage of participants who drove under the influence of alcohol and/or cannabis in the past 90 days
Measured: Assessed at 6 month follow-up
Riding With Impaired Driver
Total number of participants who self-reported an increased frequency of riding with an impaired driver (RWID) who had consumed the specified substance or combination of substances in the past 3 months at 3- and/or 6-month-follow-up when compared to baseline as indicated by a binary (1 = increased frequency; 0 = maintained or reduced frequency)
Measured: Baseline through month 6
Perceived Descriptive Norms
Percentage of their peers (0% of their peers-100% of their peers) participants believe have consumed alcohol, cannabis, or both simultaneously in past month
Measured: 6 month follow-up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Jul 2021
- Study start1 Jan 2022
- Primary completion30 Mar 2025
- Study completion31 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Substance-Related DisordersStudies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Teen participants will be randomized to a single-session, self-guided web-intervention called webCHAT or usual care after completing an online baseline survey. Participants will complete follow-up surveys 3 and 6-months after baseline.
- Masking
- None (open label)
- Enrolment
- 198 participants (actual)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Responsible party
- Principal investigator, Karen Osilla, Stanford University
- Investigators
- Karen Osilla, PhD, Principal investigator, Professor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04959461
- Sponsor's protocol ID
- 61874
- Other IDs
- R34AA027689
- Acronym
- webCHAT
- Status last verified
- Mar 2026
- First submitted
- 16 Jun 2021
- Last updated
- 27 Mar 2026
- Results posted
- Yes, on ClinicalTrials.gov
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Nameth K, Ueland E, D'Amico EJ, Osilla KC. Feasibility and acceptability of a web-intervention to prevent alcohol and cannabis-impaired driving among adolescents in driver education. Addict Sci Clin Pract. 2024 Nov 18;19(1):83. doi: 10.1186/s13722-024-00513-2.
PubMed 39558402Osilla KC, Nameth K, Rodriguez A, Hummer JF, D'Amico EJ. Preventing alcohol and cannabis-impaired driving among adolescents: Effects of a web-intervention in a driver education program. J Subst Use Addict Treat. 2026 Jul;186:209945. doi: 10.1016/j.josat.2026.209945. Epub 2026 Mar 17.
PubMed 41850531Osilla KC, D'Amico EJ, Smart R, Rodriguez A, Nameth K, Hummer J. Study design to evaluate a web-intervention to prevent alcohol and cannabis-impaired driving and use among adolescents in driver education. Addict Sci Clin Pract. 2023 Mar 24;18(1):17. doi: 10.1186/s13722-023-00373-2.
PubMed 36964608
Study at a glance
From the registry record, last updated by the sponsor on 27 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Pilot Trial to Prevent Intoxicated and Impaired Driving Among Adolescents
- ClinicalTrials.gov ID
- NCT04959461
- Acronym / sponsor ID
- webCHAT / 61874
- Conditions
- Substance-Related Disorders
- Keywords
- impaired driving
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 198 participants (actual)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Collaborators
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Study start
- 1 Jan 2022 (actual)
- Primary completion
- 30 Mar 2025 (actual)
- Study completion
- 31 Aug 2025 (actual)
- First posted
- 13 Jul 2021 (actual)
- Results
- Posted 27 Mar 2026
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The primary goal of this project is to evaluate the efficacy of webCHAT, a single-session web-intervention, on reducing impaired driving among adolescents receiving behind-the-wheel training at driver education programs.
Detailed description
Alcohol and marijuana (AM) are the most commonly used substances among adolescents in the U.S. The consequences of AM use are significantly higher relative to use of either substance alone. This study builds on effective interventions that have demonstrated reductions in alcohol and/or marijuana use and reduced consequences one year later, and proposes to adapt one of those interventions, CHAT, to the web (web-CHAT). The investigators will evaluate the efficacy of web-CHAT among 15.5-17-year-old adolescents (n=150) recruited when teen participants are attending behind-the-wheel training. The study has the potential to promote public welfare by improving adolescent health outcomes and reducing risky driving behaviors that can have substantial monetary and social costs, as well as by providing unique insight into what mediates reduced risky driving attitudes behaviors among those in the intervention. The study is innovative because it is for both youth who are at risk for substance use as well as those who are not, and it is delivered during a teachable moment when adolescents receive driver's education. Finally, this study can provide unique insights about the efficacy of web-CHAT to reduce marijuana initiation, use, and risky driving attitudes in the context of a changing marijuana policy climate. A 3-year study is proposed to test the feasibility of research procedures in a driver education setting and pilot the efficacy of web-CHAT. The investigators will test whether web-CHAT reduces alcohol and/or marijuana initiation or use compared to teens in UC, at three and six-month follow-up.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Teen participants will be randomized to a single-session, self-guided web-intervention called webCHAT or usual care after completing an online baseline survey. Participants will complete follow-up surveys 3 and 6-months after baseline.
| Arm | Type | Receives |
|---|---|---|
| webCHAT | Experimental | Behavioral: webCHATSingle session 20-40minute self-guided web program that discusses promotes healthy decision making around driving and discusses the risks of alcohol and cannabis-influenced driving. |
| Usual Care | Active comparator | Behavioral: Usual CareExisting driving school education |
Who may qualify
- Ages
- 15 to 17 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (3 listed)
- 15.5-17 year olds enrolled in driver education school
- Access to a computer or smartphone
- Within one month of taking their driver's licensing exam
Key exclusion criteria (3 listed)
- Under 15.5 or over 17 years old
- Not enrolled in one of the participating schools
- Non-English speaking
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| webCHATA self-guided, single session web intervention that utilizes a motivational interviewing style to prevent impaired driving | Behavioural | webCHAT |
| Usual Care6 hours of driver education | Behavioural | Usual Care |
Primary outcome
Alcohol and/or Cannabis Use
Time frame: Baseline through 6-month-follow-up
Total number of participants who self-reported an increased frequency of using the specified substance or substance combination in the past 3 months at 3- and/or 6-month-follow-up when compared to baseline, as denoted by a binary variable (1 = increased frequency; 0 = maintained or decreased frequency)
3 secondary outcomes
Driving Under the Influence
Time frame: Assessed at 6 month follow-up
Riding With Impaired Driver
Time frame: Baseline through month 6
Perceived Descriptive Norms
Time frame: 6 month follow-up
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Mar 2026.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Background: PubMed 39558402Nameth K, Ueland E, D'Amico EJ, Osilla KC. Feasibility and acceptability of a web-intervention to prevent alcohol and cannabis-impaired driving among adolescents in driver education. Addict Sci Clin Pract. 2024 Nov 18;19(1):83. doi: 10.1186/s13722-024-00513-2.
- Derived from this study: PubMed 41850531Osilla KC, Nameth K, Rodriguez A, Hummer JF, D'Amico EJ. Preventing alcohol and cannabis-impaired driving among adolescents: Effects of a web-intervention in a driver education program. J Subst Use Addict Treat. 2026 Jul;186:209945. doi: 10.1016/j.josat.2026.209945. Epub 2026 Mar 17.
- Derived from this study: PubMed 36964608Osilla KC, D'Amico EJ, Smart R, Rodriguez A, Nameth K, Hummer J. Study design to evaluate a web-intervention to prevent alcohol and cannabis-impaired driving and use among adolescents in driver education. Addict Sci Clin Pract. 2023 Mar 24;18(1):17. doi: 10.1186/s13722-023-00373-2.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Karen Osilla, PhD principal investigator
Professor
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing webCHAT in people with Substance-Related Disorders, run by Stanford University at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 27 Mar 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Alcohol and/or Cannabis Use (time frame: Baseline through 6-month-follow-up). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04959461, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Mar 2026; AzTrials last refreshed its copy on 4 Nov 2026.